{"id":122697,"date":"2025-06-10T13:35:39","date_gmt":"2025-06-10T06:35:39","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=122697"},"modified":"2025-07-24T13:13:04","modified_gmt":"2025-07-24T06:13:04","slug":"tonios-0-5","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/tonios-0-5\/","title":{"rendered":"Tonios-0.5"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Tonios-0.5 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893114594024 (S\u0110K c\u0169: VD3-44-20)<\/strong><\/p>\n<h2>Tonios-0.5 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ng Tonios-0.5<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<p>Entecavir (d\u01b0\u1edbi d\u1ea1ng Entecavir monohydrat) 0.5mg<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893114594024 (S\u0110K c\u0169: VD3-44-20)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 4 v\u1ec9 x 7 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<p>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Tonios-0,5<\/p>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng: Entecavir l\u00e0 m\u1ed9t ch\u1ea5t t\u01b0\u01a1ng t\u1ef1 nucleosid guanosin, ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf enzyme HBV polymerase, bao g\u1ed3m 3 b\u01b0\u1edbc:<\/p>\n<ul>\n<li>\u1ee8c ch\u1ebf kh\u1ea3 n\u0103ng cung c\u1ea5p base.<\/li>\n<li>\u1ee8c ch\u1ebf sao ch\u00e9p ng\u01b0\u1ee3c chu\u1ed7i \u00e2m t\u1eeb mARN.<\/li>\n<li>\u1ee8c ch\u1ebf t\u1ed5ng h\u1ee3p chu\u1ed7i d\u01b0\u01a1ng DNA HBV.<\/li>\n<\/ul>\n<p>Hi\u1ec7u qu\u1ea3 \u1ee9c ch\u1ebf: Ki c\u1ee7a entecavir \u0111\u1ed1i v\u1edbi HBV DNA polymerase l\u00e0 0,0012 \u00b5M. T\u00e1c \u0111\u1ed9ng \u0111\u1ebfn c\u00e1c DNA polymerase c\u1ee7a ng\u01b0\u1eddi (alpha, beta, delta) \u1edf n\u1ed3ng \u0111\u1ed9 cao h\u01a1n nhi\u1ec1u (Ki 18-40 \u00b5M).<\/p>\n<p>Kh\u00e1ng thu\u1ed1c: C\u00e1c \u0111\u1ed9t bi\u1ebfn k\u1ebft h\u1ee3p (nh\u01b0 rtM204V + rtL180M + rtT184\/S202\/M250) l\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 t\u00ednh nh\u1ea1y c\u1ea3m c\u1ee7a HBV v\u1edbi entecavir (gi\u1ea3m 16-741 l\u1ea7n). Tuy nhi\u00ean, c\u00e1c \u0111\u1ed9t bi\u1ebfn \u0111\u01a1n l\u1ebb \u00edt \u1ea3nh h\u01b0\u1edfng.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu:<\/p>\n<ul>\n<li>N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng: 0,5 \u2013 1,5 gi\u1edd sau khi u\u1ed1ng.<\/li>\n<li>Sinh kh\u1ea3 d\u1ee5ng \u01b0\u1edbc t\u00ednh \u2265 70%.<\/li>\n<li>Th\u1ee9c \u0103n l\u00e0m gi\u1ea3m h\u1ea5p thu: gi\u1ea3m Cmax 44-46%, gi\u1ea3m AUC 18-20%.<\/li>\n<\/ul>\n<p>Ph\u00e2n b\u1ed1:<\/p>\n<ul>\n<li>Ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i v\u00e0o m\u00f4 (Vd &gt; t\u1ed5ng l\u01b0\u1ee3ng n\u01b0\u1edbc c\u01a1 th\u1ec3).<\/li>\n<li>G\u1eafn k\u1ebft protein huy\u1ebft t\u01b0\u01a1ng ~13%.<\/li>\n<\/ul>\n<p>Chuy\u1ec3n h\u00f3a \u2013 Th\u1ea3i tr\u1eeb:<\/p>\n<ul>\n<li>Kh\u00f4ng chuy\u1ec3n h\u00f3a qua CYP450, ch\u1ee7 y\u1ebfu b\u00e0i ti\u1ebft d\u01b0\u1edbi d\u1ea1ng nguy\u00ean v\u1eb9n qua th\u1eadn (62\u201373% li\u1ec1u d\u00f9ng).<\/li>\n<li>Th\u1eddi gian b\u00e1n th\u1ea3i pha cu\u1ed1i: 128\u2013149 gi\u1edd.<\/li>\n<li>Th\u1eddi gian b\u00e1n th\u1ea3i t\u00edch l\u0169y th\u1ef1c t\u1ebf: ~24 gi\u1edd (d\u00f9ng li\u1ec1u l\u1eb7p).<\/li>\n<li>\u0110\u1ed9 thanh th\u1ea3i qua th\u1eadn: 360\u2013471 ml\/ph\u00fat.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Tonios-0.5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p><strong>Vi\u00ean n\u00e9n Tonios-0.5<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam gan B m\u1ea1n t\u00ednh \u1edf ng\u01b0\u1eddi l\u1edbn c\u00f3 b\u1eb1ng ch\u1ee9ng ho\u1ea1t \u0111\u1ed9ng virus, men gan t\u0103ng k\u00e9o d\u00e0i v\u00e0 t\u1ed5n th\u01b0\u01a1ng gan m\u00f4 h\u1ecdc, bao g\u1ed3m c\u1ea3 tr\u01b0\u1eddng h\u1ee3p kh\u00e1ng lamivudin.<\/p>\n<figure id=\"attachment_122706\" aria-describedby=\"caption-attachment-122706\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-122706\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Tonios-05.jpg\" alt=\"Tonios-0,5\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Tonios-05.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Tonios-05-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Tonios-05-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Tonios-05-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-122706\" class=\"wp-caption-text\">Thu\u1ed1c Tonios-0.5 l\u00e0 thu\u1ed1c kh\u00e1ng virus ch\u1ee9a Entecavir, c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf s\u1ef1 nh\u00e2n l\u00ean c\u1ee7a virus vi\u00eam gan B, gi\u00fap ki\u1ec3m so\u00e1t b\u1ec7nh v\u00e0 l\u00e0m ch\u1eadm ti\u1ebfn tri\u1ec3n c\u1ee7a t\u1ed5n th\u01b0\u01a1ng gan.<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<ul>\n<li>Ng\u01b0\u1eddi l\u1edbn\/tr\u1ebb \u22652 tu\u1ed5i ch\u01b0a d\u00f9ng nucleosid: 0,5 mg\/ng\u00e0y.<\/li>\n<li>Ng\u01b0\u1eddi l\u1edbn\/tr\u1ebb \u22652 tu\u1ed5i kh\u00e1ng lamivudin: 1 mg\/ng\u00e0y.<\/li>\n<li>N\u00ean ph\u1ed1i h\u1ee3p v\u1edbi thu\u1ed1c kh\u00e1ng virus kh\u00e1c kh\u00f4ng c\u00f3 kh\u00e1ng ch\u00e9o trong tr\u01b0\u1eddng h\u1ee3p kh\u00e1ng lamivudin.<\/li>\n<\/ul>\n<p><strong><em>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb:<\/em><\/strong><\/p>\n<p>Ng\u01b0\u1eddi l\u1edbn:<\/p>\n<ul>\n<li>HBeAg (+): \u00edt nh\u1ea5t 12 th\u00e1ng sau chuy\u1ec3n \u0111\u1ed5i huy\u1ebft thanh HBe ho\u1eb7c \u0111\u1ebfn khi m\u1ea5t HBsAg.<\/li>\n<li>HBeAg (\u2013): \u0111\u1ebfn khi m\u1ea5t HBsAg ho\u1eb7c m\u1ea5t hi\u1ec7u l\u1ef1c.<\/li>\n<li>Kh\u00f4ng khuy\u1ebfn c\u00e1o ng\u1eebng \u0111i\u1ec1u tr\u1ecb n\u1ebfu c\u00f3 x\u01a1 gan ho\u1eb7c b\u1ec7nh gan m\u1ea5t b\u00f9.<\/li>\n<\/ul>\n<p>Tr\u1ebb em:<\/p>\n<ul>\n<li>HBeAg (+): t\u01b0\u01a1ng t\u1ef1 ng\u01b0\u1eddi l\u1edbn, n\u00ean theo d\u00f5i sau khi ng\u01b0ng.<\/li>\n<li>HBeAg (\u2013): \u0111\u1ebfn khi m\u1ea5t HBsAg ho\u1eb7c m\u1ea5t hi\u1ec7u l\u1ef1c.<\/li>\n<li>D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc ch\u01b0a \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u \u1edf tr\u1ebb suy gan\/th\u1eadn.<\/li>\n<\/ul>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>U\u1ed1ng vi\u00ean n\u00e9n Tonios khi b\u1ee5ng \u0111\u00f3i (\u00edt nh\u1ea5t 2 gi\u1edd tr\u01b0\u1edbc\/sau \u0103n).<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Tonios-0.5 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi Entecavir c\u00f3 trong Tonios<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng thu\u1ed1c, c\u1ea7n \u0111\u00e1nh gi\u00e1 k\u1ef9 t\u00ecnh tr\u1ea1ng s\u1ee9c kh\u1ecfe t\u1ed5ng qu\u00e1t c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh, \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00e1c b\u1ec7nh l\u00fd gan, th\u1eadn ho\u1eb7c r\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a.<br \/>\nVi\u1ec7c s\u1eed d\u1ee5ng k\u00e9o d\u00e0i ho\u1eb7c v\u01b0\u1ee3t qu\u00e1 li\u1ec1u khuy\u1ebfn c\u00e1o c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 g\u1eb7p t\u00e1c d\u1ee5ng ngo\u1ea1i \u00fd.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng thu\u1ed1c cho ng\u01b0\u1eddi cao tu\u1ed5i, tr\u1ebb em, ho\u1eb7c b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<br \/>\nTrong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, n\u1ebfu xu\u1ea5t hi\u1ec7n bi\u1ec3u hi\u1ec7n b\u1ea5t th\u01b0\u1eddng, c\u1ea7n ng\u1eebng thu\u1ed1c v\u00e0 th\u00f4ng b\u00e1o v\u1edbi b\u00e1c s\u0129.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>M\u1ed9t s\u1ed1 ng\u01b0\u1eddi d\u00f9ng c\u00f3 th\u1ec3 g\u1eb7p c\u00e1c ph\u1ea3n \u1ee9ng kh\u00f4ng mong mu\u1ed1n nh\u01b0 bu\u1ed3n n\u00f4n, ch\u00f3ng m\u1eb7t, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a ho\u1eb7c n\u1ed5i m\u1ea9n da. Trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p hi\u1ebfm, c\u00f3 th\u1ec3 x\u1ea3y ra ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn, bao g\u1ed3m kh\u00f3 th\u1edf, ph\u00f9 m\u1eb7t ho\u1eb7c ph\u00e1t ban to\u00e0n th\u00e2n. N\u1ebfu g\u1eb7p b\u1ea5t k\u1ef3 d\u1ea5u hi\u1ec7u n\u00e0o nghi ng\u1edd l\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a thu\u1ed1c, c\u1ea7n ng\u01b0ng s\u1eed d\u1ee5ng v\u00e0 \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf g\u1ea7n nh\u1ea5t \u0111\u1ec3 \u0111\u01b0\u1ee3c x\u1eed l\u00fd k\u1ecbp th\u1eddi.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Th\u1eadn tr\u1ecdng khi d\u00f9ng chung v\u1edbi thu\u1ed1c g\u00e2y suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn ho\u1eb7c c\u1ea1nh tranh b\u00e0i ti\u1ebft \u1edf \u1ed1ng th\u1eadn.<\/li>\n<li>Kh\u00f4ng c\u00f3 t\u01b0\u01a1ng t\u00e1c \u0111\u00e1ng k\u1ec3 v\u1edbi lamivudin, adefovir dipivoxil ho\u1eb7c tenofovir disoproxil fumarat.<\/li>\n<li>N\u00ean theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn n\u1ebfu ph\u1ed1i h\u1ee3p thu\u1ed1c \u0111\u00e0o th\u1ea3i qua th\u1eadn.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<ul>\n<li>Ph\u1ee5 n\u1eef trong \u0111\u1ed9 tu\u1ed5i sinh \u0111\u1ebb: C\u1ea7n bi\u1ec7n ph\u00e1p tr\u00e1nh thai hi\u1ec7u qu\u1ea3.<\/li>\n<li>Ph\u1ee5 n\u1eef mang thai: Ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u an to\u00e0n, ch\u1ec9 s\u1eed d\u1ee5ng n\u1ebfu th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft.<\/li>\n<li>Chuy\u1ec3n d\u1ea1 \u2013 sinh n\u1edf: Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u v\u1ec1 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn l\u00e2y truy\u1ec1n HBV t\u1eeb m\u1eb9 sang con, n\u00ean \u00e1p d\u1ee5ng bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba th\u00edch h\u1ee3p.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y c\u1ea3m gi\u00e1c m\u1ec7t m\u1ecfi, bu\u1ed3n ng\u1ee7 ho\u1eb7c gi\u1ea3m kh\u1ea3 n\u0103ng t\u1eadp trung \u1edf m\u1ed9t s\u1ed1 ng\u01b0\u1eddi d\u00f9ng. Do \u0111\u00f3, c\u1ea7n c\u1ea9n tr\u1ecdng khi s\u1eed d\u1ee5ng thu\u1ed1c n\u1ebfu b\u1ea1n \u0111ang \u0111i\u1ec1u khi\u1ec3n ph\u01b0\u01a1ng ti\u1ec7n giao th\u00f4ng ho\u1eb7c l\u00e0m vi\u1ec7c v\u1edbi m\u00e1y m\u00f3c n\u1eb7ng. N\u00ean theo d\u00f5i ph\u1ea3n \u1ee9ng c\u1ee7a c\u01a1 th\u1ec3 trong l\u1ea7n d\u00f9ng \u0111\u1ea7u ti\u00ean \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh m\u1ee9c \u0111\u1ed9 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e0m vi\u1ec7c<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Khi s\u1eed d\u1ee5ng qu\u00e1 li\u1ec1u, ng\u01b0\u1eddi b\u1ec7nh c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 bu\u1ed3n n\u00f4n nghi\u00eam tr\u1ecdng, n\u00f4n li\u00ean t\u1ee5c, ti\u00eau ch\u1ea3y, r\u1ed1i lo\u1ea1n nh\u1ecbp tim ho\u1eb7c ng\u1ea5t x\u1ec9u. Trong tr\u01b0\u1eddng h\u1ee3p nghi ng\u1edd qu\u00e1 li\u1ec1u, c\u1ea7n \u0111\u01b0a ng\u01b0\u1eddi b\u1ec7nh \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf ngay l\u1eadp t\u1ee9c \u0111\u1ec3 \u0111\u01b0\u1ee3c h\u1ed7 tr\u1ee3 y t\u1ebf k\u1ecbp th\u1eddi. Vi\u1ec7c x\u1eed tr\u00ed bao g\u1ed3m \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 h\u1ed7 tr\u1ee3 ch\u1ee9c n\u0103ng s\u1ed1ng, c\u00f3 th\u1ec3 c\u1ea7n bi\u1ec7n ph\u00e1p lo\u1ea1i b\u1ecf thu\u1ed1c ra kh\u1ecfi c\u01a1 th\u1ec3 n\u1ebfu \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n s\u1edbm.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<ul>\n<li>Gi\u1eef Tonios-0.5 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/li>\n<li>Kh\u00f4ng \u0111\u1ec3 Tonios-0.5 trong t\u1ea7m v\u1edbi tr\u1ebb em<\/li>\n<li>Kh\u00f4ng s\u1eed d\u1ee5ng Tonios-0.5 khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Tonios-0.5 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Tonios-0.5 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Tonios-0.5 c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p Tonios-0.5 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Tonios-0.5 nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/entecavir-teva-0-5mg\/\">Entecavir Teva 0.5mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n l\u00e0 Entecavir 0.5 mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Remedica Ltd., \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam gan B m\u00e3n t\u00ednh (HBV).<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/entecavir-stada\/\">Entecavir Stella 0,5mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n l\u00e0 Entecavir 0.5 mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Chi nh\u00e1nh C\u00f4ng ty TNHH LD Stella-Vi\u1ec7t Nam, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam gan B m\u00e3n t\u00ednh (HBV).<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Dimou E, Papadimitropoulos V, Hadziyannis SJ (2007). The role of entecavir in the treatment of chronic hepatitis B. Ther Clin Risk Manag. Truy c\u1eadp ng\u00e0y 4 th\u00e1ng 6 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2387288\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2387288\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Tonios-0,5 l\u00e0 thu\u1ed1c kh\u00e1ng virus ch\u1ee9a Entecavir, c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf s\u1ef1 nh\u00e2n l\u00ean c\u1ee7a virus vi\u00eam gan B, gi\u00fap ki\u1ec3m so\u00e1t b\u1ec7nh v\u00e0 l\u00e0m ch\u1eadm ti\u1ebfn tri\u1ec3n c\u1ee7a t\u1ed5n th\u01b0\u01a1ng gan.<\/p>\n","protected":false},"author":1,"featured_media":123993,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-122697","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/122697","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=122697"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/123993"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=122697"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=122697"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=122697"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}