{"id":122373,"date":"2025-06-07T15:21:06","date_gmt":"2025-06-07T08:21:06","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=122373"},"modified":"2025-12-23T15:26:30","modified_gmt":"2025-12-23T08:26:30","slug":"ursobil-300","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/ursobil-300\/","title":{"rendered":"URSOBIL 300"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>URSOBIL 300 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi ABC Farmaceutici S.P.A, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 800110022025 (VN-20260-17).<\/strong><\/p>\n<h2>URSOBIL 300 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean n\u00e9n<strong> Ursobil 300<\/strong> ch\u1ee9a 300mg <strong>Acid ursodeoxycholic<\/strong> (UDCA). Ngo\u00e0i ra, thu\u1ed1c c\u00f2n c\u00f3 c\u00e1c t\u00e1 d\u01b0\u1ee3c nh\u01b0 lactose, tinh b\u1ed9t ng\u00f4, polyvinylpyrrolidon, b\u1ed9t talc v\u00e0 magnesi stearat.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 800110022025 (VN-20260-17)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Italy<\/p>\n<figure id=\"attachment_122374\" aria-describedby=\"caption-attachment-122374\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-122374\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Usobil-300.jpg\" alt=\"URSOBIL 300 \u0111i\u1ec1u tr\u1ecb x\u01a1 m\u1eadt nguy\u00ean ph\u00e1t\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Usobil-300.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Usobil-300-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Usobil-300-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Usobil-300-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-122374\" class=\"wp-caption-text\">URSOBIL 300 \u0111i\u1ec1u tr\u1ecb x\u01a1 m\u1eadt nguy\u00ean ph\u00e1t<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c URSOBIL 300<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Acid ursodeoxycholic (UDCA) l\u00e0 m\u1ed9t acid m\u1eadt \u01b0a n\u01b0\u1edbc t\u1ef1 nhi\u00ean c\u00f3 trong d\u1ecbch m\u1eadt ng\u01b0\u1eddi. Khi \u0111\u01b0\u1ee3c h\u1ea5p thu v\u00e0o c\u01a1 th\u1ec3, UDCA tr\u1edf th\u00e0nh acid m\u1eadt ch\u00ednh, gi\u00fap:<\/p>\n<ul>\n<li>Thay th\u1ebf c\u00e1c acid m\u1eadt \u0111\u1ed9c h\u1ea1i: UDCA chi\u1ebfm ch\u1ed7 v\u00e0 thay th\u1ebf c\u00e1c acid m\u1eadt \u01b0a n\u01b0\u1edbc n\u1ed9i sinh \u0111\u1ed9c h\u1ea1i th\u01b0\u1eddng t\u00edch t\u1ee5 trong c\u00e1c b\u1ec7nh l\u00fd gan \u1ee9 m\u1eadt, t\u1eeb \u0111\u00f3 gi\u1ea3m g\u00e1nh n\u1eb7ng cho gan.<\/li>\n<li>B\u1ea3o v\u1ec7 t\u1ebf b\u00e0o gan v\u00e0 \u1ed1ng m\u1eadt: Thu\u1ed1c b\u1ea3o v\u1ec7 c\u00e1c t\u1ebf b\u00e0o bi\u1ec3u m\u00f4 c\u1ee7a \u1ed1ng d\u1eabn m\u1eadt b\u1ecb t\u1ed5n th\u01b0\u01a1ng ch\u1ed1ng l\u1ea1i t\u00e1c \u0111\u1ed9ng \u0111\u1ed9c c\u1ee7a c\u00e1c acid m\u1eadt, \u0111\u1ed3ng th\u1eddi \u1ee9c ch\u1ebf s\u1ef1 t\u1ef1 h\u1ee7y ho\u1ea1i c\u1ee7a t\u1ebf b\u00e0o gan.<\/li>\n<li>\u0110i\u1ec1u h\u00f2a mi\u1ec5n d\u1ecbch v\u00e0 k\u00edch th\u00edch ti\u1ebft m\u1eadt: UDCA c\u00f3 t\u00e1c \u0111\u1ed9ng \u0111i\u1ec1u h\u00f2a ch\u1ee9c n\u0103ng mi\u1ec5n d\u1ecbch v\u00e0 k\u00edch th\u00edch qu\u00e1 tr\u00ecnh ti\u1ebft m\u1eadt t\u1eeb t\u1ebf b\u00e0o gan v\u00e0 t\u1ebf b\u00e0o l\u00f3t c\u1ee7a \u1ed1ng d\u1eabn m\u1eadt, gi\u00fap c\u1ea3i thi\u1ec7n l\u01b0u l\u01b0\u1ee3ng m\u1eadt.<\/li>\n<li>H\u00f2a tan s\u1ecfi cholesterol: UDCA l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng h\u00f2a tan cholesterol trong m\u1eadt b\u1eb1ng c\u00e1ch gi\u1ea3m b\u00e0i ti\u1ebft cholesterol v\u00e0o m\u1eadt (qua vi\u1ec7c gi\u1ea3m h\u1ea5p thu cholesterol trong ru\u1ed9t v\u00e0 t\u1ed5ng h\u1ee3p \u1edf gan), c\u0169ng nh\u01b0 t\u0103ng l\u01b0\u1ee3ng acid m\u1eadt to\u00e0n ph\u1ea7n \u0111\u1ec3 h\u00f2a tan cholesterol \u1edf d\u1ea1ng mixen. \u0110i\u1ec1u n\u00e0y gi\u00fap chuy\u1ec3n m\u1eadt c\u00f3 s\u1ecfi th\u00e0nh m\u1eadt kh\u00f4ng s\u1ecfi, gi\u1ea3m s\u1ef1 b\u00e3o h\u00f2a cholesterol trong m\u1eadt v\u00e0 t\u0103ng c\u01b0\u1eddng mu\u1ed1i m\u1eadt, t\u1eeb \u0111\u00f3 c\u1ea3i thi\u1ec7n l\u01b0u th\u00f4ng m\u1eadt v\u00e0 l\u00e0m r\u1ed7ng t\u00fai m\u1eadt.<\/li>\n<\/ul>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu: UDCA d\u1ec5 d\u00e0ng \u0111\u01b0\u1ee3c h\u1ea5p thu qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, ch\u1ee7 y\u1ebfu b\u1eb1ng khu\u1ebfch t\u00e1n th\u1ee5 \u0111\u1ed9ng. M\u1ee9c \u0111\u1ed9 h\u1ea5p thu kho\u1ea3ng 50% \u1edf ng\u01b0\u1eddi kh\u00f4ng b\u1ec7nh gan v\u00e0 gi\u1ea3m khi b\u1ec7nh gan tr\u1edf n\u1eb7ng.<\/li>\n<li>Ph\u00e2n b\u1ed1 v\u00e0 chuy\u1ec3n h\u00f3a: Sau khi h\u1ea5p thu, UDCA qua gan, k\u1ebft h\u1ee3p v\u1edbi glycin ho\u1eb7c taurin, sau \u0111\u00f3 \u0111\u01b0\u1ee3c ti\u1ebft v\u00e0o m\u1eadt. D\u1ea1ng li\u00ean h\u1ee3p n\u00e0y ti\u1ebfp t\u1ee5c \u0111\u01b0\u1ee3c h\u1ea5p thu \u1edf ru\u1ed9t non. Ph\u1ea7n UDCA kh\u00f4ng \u0111\u01b0\u1ee3c h\u1ea5p thu s\u1ebd \u0111i \u0111\u1ebfn ru\u1ed9t k\u1ebft, n\u01a1i n\u00f3 \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a th\u00e0nh acid lithocholic. M\u1ed9t ph\u1ea7n nh\u1ecf acid lithocholic \u0111\u01b0\u1ee3c t\u00e1i h\u1ea5p thu v\u00e0 li\u00ean h\u1ee3p \u1edf gan tr\u01b0\u1edbc khi b\u00e0i ti\u1ebft qua m\u1eadt ho\u1eb7c ph\u00e2n.<\/li>\n<li>Th\u1ea3i tr\u1eeb: Ursobil v\u00e0 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua m\u1eadt v\u00e0 ph\u00e2n. Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, l\u01b0\u1ee3ng thu\u1ed1c b\u00e0i ti\u1ebft qua n\u01b0\u1edbc ti\u1ec3u c\u00f3 th\u1ec3 t\u0103ng nh\u01b0ng th\u01b0\u1eddng d\u01b0\u1edbi 1%, tr\u1eeb tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh gan \u1ee9 m\u1eadt n\u1eb7ng.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c URSOBIL 300 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb x\u01a1 gan m\u1eadt nguy\u00ean ph\u00e1t (PBC): Thu\u1ed1c gi\u00fap c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng gan, b\u1ea3o v\u1ec7 t\u1ebf b\u00e0o gan v\u00e0 \u1ed1ng d\u1eabn m\u1eadt kh\u1ecfi t\u00e1c \u0111\u1ed9ng c\u1ee7a c\u00e1c acid m\u1eadt \u0111\u1ed9c h\u1ea1i t\u00edch t\u1ee5.<\/li>\n<li>L\u00e0m tan s\u1ecfi m\u1eadt: \u0110\u1eb7c bi\u1ec7t hi\u1ec7u qu\u1ea3 v\u1edbi s\u1ecfi cholesterol kh\u00f4ng b\u1ecb v\u00f4i h\u00f3a, kh\u00f4ng c\u1ea3n tia X-quang, c\u00f3 \u0111\u01b0\u1eddng k\u00ednh d\u01b0\u1edbi 20mm. Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng cho nh\u1eefng tr\u01b0\u1eddng h\u1ee3p s\u1ecfi trong t\u00fai m\u1eadt khi ch\u1ee9c n\u0103ng t\u00fai m\u1eadt c\u00f2n t\u1ed1t, s\u1ecfi v\u1ee5n ho\u1eb7c s\u1ecfi t\u00e1i ph\u00e1t trong \u1ed1ng d\u1eabn m\u1eadt sau ph\u1eabu thu\u1eadt, ho\u1eb7c cho nh\u1eefng ng\u01b0\u1eddi kh\u00f4ng th\u1ec3 ph\u1eabu thu\u1eadt c\u1eaft b\u1ecf t\u00fai m\u1eadt.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c URSOBIL 300<\/h2>\n<ul>\n<li>\u0110\u1ed1i v\u1edbi x\u01a1 gan m\u1eadt nguy\u00ean ph\u00e1t:\n<ul>\n<li>Li\u1ec1u d\u00f9ng cho ng\u01b0\u1eddi l\u1edbn l\u00e0 13 &#8211; 15 mg UDCA\/kg th\u1ec3 tr\u1ecdng m\u1ed7i ng\u00e0y, chia l\u00e0m 2-4 l\u1ea7n.<\/li>\n<li>C\u1ea7n ki\u1ec3m tra ch\u1ee9c n\u0103ng gan (\u03b3-GT, phosphatase ki\u1ec1m, AST, ALT) v\u00e0 bilirubin m\u1ed7i th\u00e1ng trong 6 th\u00e1ng \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb, sau \u0111\u00f3 ki\u1ec3m tra \u0111\u1ecbnh k\u1ef3 6 th\u00e1ng m\u1ed9t l\u1ea7n.<\/li>\n<\/ul>\n<\/li>\n<li>\u0110\u1ed1i v\u1edbi l\u00e0m tan s\u1ecfi m\u1eadt:\n<ul>\n<li>Li\u1ec1u d\u00f9ng cho ng\u01b0\u1eddi l\u1edbn l\u00e0 t\u1eeb 8 \u0111\u1ebfn 12 mg UDCA\/kg th\u1ec3 tr\u1ecdng m\u1ed7i ng\u00e0y, chia ra 2-3 l\u1ea7n u\u1ed1ng.<\/li>\n<li>C\u1ea7n ki\u1ec3m tra ti\u1ebfn tri\u1ec3n s\u1ecfi m\u1eadt qua si\u00eau \u00e2m v\u00e0o th\u00e1ng th\u1ee9 6 v\u00e0 12, sau \u0111\u00f3 m\u1ed7i 1-3 th\u00e1ng.<\/li>\n<li>Sau khi s\u1ecfi tan ho\u00e0n to\u00e0n, c\u1ea7n ti\u1ebfp t\u1ee5c s\u1eed d\u1ee5ng thu\u1ed1c th\u00eam 3-4 th\u00e1ng \u0111\u1ec3 ng\u0103n ng\u1eeba t\u00e1i ph\u00e1t. N\u1ebfu sau 12 th\u00e1ng \u0111i\u1ec1u tr\u1ecb m\u00e0 s\u1ecfi m\u1eadt kh\u00f4ng c\u00f3 d\u1ea5u hi\u1ec7u tan, li\u1ec7u ph\u00e1p UDCA c\u00f3 th\u1ec3 kh\u00f4ng hi\u1ec7u qu\u1ea3 v\u00e0 c\u1ea7n c\u00e2n nh\u1eafc ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb kh\u00e1c.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c URSOBIL 300<\/h2>\n<p>Ursobil 300 \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng. \u0110\u1ec3 \u0111\u1ea1t hi\u1ec7u qu\u1ea3 t\u1ed1t nh\u1ea5t, b\u1ea1n n\u00ean u\u1ed1ng thu\u1ed1c sau b\u1eefa \u0103n, \u0111\u1eb7c bi\u1ec7t li\u1ec1u cu\u1ed1i c\u00f9ng trong ng\u00e0y n\u00ean u\u1ed1ng sau b\u1eefa t\u1ed1i.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c URSOBIL 300 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Qu\u00e1 m\u1eabn v\u1edbi UDCA, c\u00e1c acid m\u1eadt kh\u00e1c ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>Vi\u00eam t\u00fai m\u1eadt ho\u1eb7c \u1ed1ng d\u1eabn m\u1eadt c\u1ea5p t\u00ednh.<\/li>\n<li>T\u1eafc \u1ed1ng d\u1eabn m\u1eadt ho\u00e0n to\u00e0n.<\/li>\n<li>C\u01a1n \u0111au qu\u1eb7n m\u1eadt th\u01b0\u1eddng xuy\u00ean.<\/li>\n<li>S\u1ecfi m\u1eadt v\u00f4i h\u00f3a th\u1ea5y tr\u00ean X-quang.<\/li>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai, \u0111ang cho con b\u00fa ho\u1eb7c d\u1ef1 \u0111\u1ecbnh c\u00f3 thai.<\/li>\n<li>Tr\u1ebb em d\u01b0\u1edbi 12 tu\u1ed5i.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c URSOBIL 300<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Theo d\u00f5i ch\u1ee9c n\u0103ng gan: Trong 3 th\u00e1ng \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb, c\u1ea7n theo d\u00f5i c\u00e1c th\u00f4ng s\u1ed1 ch\u1ee9c n\u0103ng gan (AST, ALT, \u03b3-GT) m\u1ed7i 4 tu\u1ea7n, sau \u0111\u00f3 m\u1ed7i 3 th\u00e1ng. Vi\u1ec7c n\u00e0y gi\u00fap \u0111\u00e1nh gi\u00e1 \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u tr\u1ecb v\u00e0 ph\u00e1t hi\u1ec7n s\u1edbm t\u00ecnh tr\u1ea1ng suy gan.<\/li>\n<li>Ki\u1ec3m tra s\u1ecfi m\u1eadt: Khi d\u00f9ng \u0111\u1ec3 t\u00e1n s\u1ecfi cholesterol, khuy\u1ebfn c\u00e1o kh\u1ea3o s\u00e1t t\u00fai m\u1eadt t\u1ed5ng qu\u00e1t (ch\u1ee5p X-quang) sau 6-10 th\u00e1ng \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 ti\u1ebfn tri\u1ec3n v\u00e0 ph\u00e1t hi\u1ec7n v\u00f4i h\u00f3a s\u1ecfi m\u1eadt.<\/li>\n<li>Ti\u00eau ch\u1ea3y k\u00e9o d\u00e0i: N\u1ebfu b\u1ecb ti\u00eau ch\u1ea3y, c\u1ea7n gi\u1ea3m li\u1ec1u v\u00e0 ng\u1eebng \u0111i\u1ec1u tr\u1ecb n\u1ebfu ti\u00eau ch\u1ea3y k\u00e9o d\u00e0i.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c lactose: Thu\u1ed1c c\u00f3 ch\u1ee9a lactose, kh\u00f4ng n\u00ean d\u00f9ng cho b\u1ec7nh nh\u00e2n c\u00f3 v\u1ea5n \u0111\u1ec1 di truy\u1ec1n hi\u1ebfm g\u1eb7p v\u1ec1 kh\u00f4ng dung n\u1ea1p galactose, thi\u1ebfu h\u1ee5t Lapp lactase ho\u1eb7c k\u00e9m h\u1ea5p thu glucose-galactose.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>Th\u01b0\u1eddng g\u1eb7p: Ti\u00eau ch\u1ea3y, ph\u00e2n nh\u00e3o.<\/li>\n<li>Hi\u1ebfm g\u1eb7p: \u0110au b\u1ee5ng tr\u00ean b\u00ean ph\u1ea3i tr\u1ea7m tr\u1ecdng, v\u00f4i h\u00f3a s\u1ecfi m\u1eadt, x\u01a1 gan m\u1ea5t b\u00f9 (th\u01b0\u1eddng ph\u1ee5c h\u1ed3i sau khi ng\u1eebng thu\u1ed1c), n\u1ed5i m\u1ec1 \u0111ay.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Cholestyramin, Colestipol ho\u1eb7c thu\u1ed1c kh\u00e1ng acid ch\u1ee9a nh\u00f4m hydroxid\/smectit: C\u00e1c thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 g\u1eafn k\u1ebft v\u1edbi UDCA trong ru\u1ed9t, l\u00e0m gi\u1ea3m h\u1ea5p thu v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a Ursobil. N\u00ean u\u1ed1ng c\u00e1ch nhau \u00edt nh\u1ea5t 2 gi\u1edd.<\/li>\n<li>Cyclosporin: Ursobil c\u00f3 th\u1ec3 l\u00e0m t\u0103ng h\u1ea5p thu cyclosporin t\u1eeb ru\u1ed9t. C\u1ea7n ki\u1ec3m tra n\u1ed3ng \u0111\u1ed9 cyclosporin trong m\u00e1u v\u00e0 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u n\u1ebfu c\u1ea7n.<\/li>\n<li>Ciprofloxacin: Ursobil c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m h\u1ea5p thu ciprofloxacin.<\/li>\n<li>Nitrendipin: Ursobil l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh v\u00e0 di\u1ec7n t\u00edch d\u01b0\u1edbi \u0111\u01b0\u1eddng cong c\u1ee7a nitrendipin.<\/li>\n<li>Dapson: \u0110\u00e3 c\u00f3 b\u00e1o c\u00e1o v\u1ec1 t\u01b0\u01a1ng t\u00e1c l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u1ee7a dapson.<\/li>\n<li>Estrogen, thu\u1ed1c tr\u00e1nh thai n\u1ed9i ti\u1ebft t\u1ed1, m\u1ed9t s\u1ed1 thu\u1ed1c h\u1ea1 cholesterol m\u00e1u (nh\u01b0 clofibrat): C\u00e1c thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 l\u00e0m t\u0103ng s\u1ecfi m\u1eadt, \u0111\u1ed1i kh\u00e1ng v\u1edbi t\u00e1c d\u1ee5ng l\u00e0m tan s\u1ecfi c\u1ee7a UDCA. N\u00ean tr\u00e1nh k\u1ebft h\u1ee3p.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<ul>\n<li>Th\u1eddi k\u1ef3 mang thai: Ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng UDCA trong thai k\u1ef3, \u0111\u1eb7c bi\u1ec7t 3 th\u00e1ng \u0111\u1ea7u. Kh\u00f4ng d\u00f9ng thu\u1ed1c trong th\u1eddi k\u1ef3 mang thai tr\u1eeb khi l\u1ee3i \u00edch r\u00f5 r\u00e0ng v\u01b0\u1ee3t tr\u1ed9i. Ph\u1ee5 n\u1eef trong \u0111\u1ed9 tu\u1ed5i sinh \u0111\u1ebb c\u1ea7n s\u1eed d\u1ee5ng bi\u1ec7n ph\u00e1p ng\u1eeba thai \u0111\u00e1ng tin c\u1eady (\u01b0u ti\u00ean kh\u00f4ng n\u1ed9i ti\u1ebft t\u1ed1 \u0111\u1ec3 tr\u00e1nh t\u0103ng nguy c\u01a1 s\u1ecfi m\u1eadt).<\/li>\n<li>Th\u1eddi k\u1ef3 cho con b\u00fa: Ch\u01b0a x\u00e1c \u0111\u1ecbnh li\u1ec7u UDCA c\u00f3 \u0111i v\u00e0o s\u1eefa m\u1eb9 hay kh\u00f4ng. Kh\u00f4ng n\u00ean d\u00f9ng thu\u1ed1c khi \u0111ang cho con b\u00fa. N\u1ebfu b\u1eaft bu\u1ed9c ph\u1ea3i \u0111i\u1ec1u tr\u1ecb, c\u1ea7n ng\u01b0ng cho con b\u00fa.<\/li>\n<\/ul>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>D\u00f9ng qu\u00e1 li\u1ec1u Ursobil 300 c\u00f3 th\u1ec3 g\u00e2y ti\u00eau ch\u1ea3y. C\u00e1c tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u kh\u00e1c th\u01b0\u1eddng \u00edt x\u1ea3y ra do kh\u1ea3 n\u0103ng h\u1ea5p thu c\u1ee7a thu\u1ed1c gi\u1ea3m khi li\u1ec1u t\u0103ng, v\u00e0 ph\u1ea7n l\u1edbn thu\u1ed1c s\u1ebd \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua ph\u00e2n. Khi g\u1eb7p ti\u00eau ch\u1ea3y, ch\u1ee7 y\u1ebfu c\u1ea7n b\u00f9 n\u01b0\u1edbc v\u00e0 \u0111i\u1ec7n gi\u1ea3i. Trong tr\u01b0\u1eddng h\u1ee3p v\u00f4 t\u00ecnh u\u1ed1ng li\u1ec1u cao, khuy\u1ebfn c\u00e1o th\u1ef1c hi\u1ec7n c\u00e1c bi\u1ec7n ph\u00e1p x\u1eed tr\u00ed nh\u01b0 ng\u1ed9 \u0111\u1ed9c th\u00f4ng th\u01b0\u1eddng v\u00e0 c\u00f3 th\u1ec3 d\u00f9ng cholestyramin.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c URSOBIL 300<\/h2>\n<p><a href=\"https:\/\/vnras.com\/drug\/ursocure-300mg\/\">Thu\u1ed1c Ursocure 300mg<\/a>, ch\u1ee9a th\u00e0nh ph\u1ea7n Ursodeoxycholic acid 300mg, ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb x\u01a1 gan m\u1eadt nguy\u00ean ph\u00e1t, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Gracure Pharmaceuticals Ltd, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 890110524924.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Thomas Pusl, Ulrich Beuers. Ursodeoxycholic acid treatment of vanishing bile duct syndromes, truy c\u1eadp ng\u00e0y 07 th\u00e1ng 06 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16773706\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/16773706\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ursobil 300 (Acid ursodeoxycholic) l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ph\u1ed5 bi\u1ebfn \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd v\u1ec1 gan v\u00e0 \u0111\u01b0\u1eddng m\u1eadt, \u0111\u1eb7c bi\u1ec7t l\u00e0 x\u01a1 gan m\u1eadt nguy\u00ean ph\u00e1t v\u00e0 s\u1ecfi m\u1eadt.<\/p>\n","protected":false},"author":1,"featured_media":122375,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-122373","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/122373","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=122373"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/122375"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=122373"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=122373"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=122373"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}