{"id":122038,"date":"2025-06-05T15:17:04","date_gmt":"2025-06-05T08:17:04","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=122038"},"modified":"2025-07-24T13:13:13","modified_gmt":"2025-07-24T06:13:13","slug":"zurelsavi-5","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/zurelsavi-5\/","title":{"rendered":"Zurelsavi 5"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <\/strong><a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/zurelsavi-5\/\">Zurelsavi 5<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m SaVi, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD3-170-22.<\/strong><\/p>\n<h2>Zurelsavi 5 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Thu\u1ed1c <strong>Zurelsavi 5<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n: Prasugrel (d\u01b0\u1edbi d\u1ea1ng prasugrel hydroclorid) 5 mg<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD3-170-22<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 03 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Zurelsavi 5<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Prasugrel l\u00e0 ho\u1ea1t ch\u1ea5t thu\u1ed9c nh\u00f3m \u1ee9c ch\u1ebf ho\u1ea1t h\u00f3a v\u00e0 k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u nh\u1edd c\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng kh\u00f4ng ph\u1ee5c h\u1ed3i do ch\u1ea5t chuy\u1ec3n h\u00f3a li\u00ean k\u1ebft v\u1edbi nh\u00f3m th\u1ee5 th\u1ec3 ADP P2Y12 tr\u00ean ti\u1ec3u c\u1ea7u. Theo ph\u1ea3n \u1ee9ng sinh l\u00fd b\u00ecnh th\u01b0\u1eddng c\u1ee7a c\u01a1 th\u1ec3, ti\u1ec3u c\u1ea7u tham gia v\u00e0o qu\u00e1 tr\u00ecnh ti\u1ebfn tri\u1ec3n c\u1ee7a c\u00e1c bi\u1ebfn ch\u1ee9ng huy\u1ebft kh\u1ed1i \u1edf b\u1ec7nh nh\u00e2n x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch, do \u0111\u00f3, \u1ee9c ch\u1ebf ch\u1ee9c n\u0103ng ti\u1ec3u c\u1ea7u gi\u00fap gi\u1ea3m thi\u1ec3u c\u00e1c bi\u1ebfn c\u1ed1 tim m\u1ea1ch nh\u01b0 nh\u1ed3i m\u00e1u c\u01a1 tim, \u0111\u1ed9t qu\u1ef5, t\u1eed vong.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Prasugrel h\u1ea5p thu nhanh ch\u00f3ng khi s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng, n\u1ed3ng \u0111\u1ed9 thu\u1ed1c \u0111\u1ea1t \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau kho\u1ea3ng 30 ph\u00fat. T\u1ef7 l\u1ec7 ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a Prasugrel v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 98%. Thu\u1ed1c chuy\u1ec3n h\u00f3a ch\u00ednh t\u1ea1i gan, qua CYP450, ph\u1ea3n \u1ee9ng li\u00ean h\u1ee3p,\u2026 Sau \u0111\u00f3, thu\u1ed1c \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb ch\u00ednh qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 ph\u00e2n, t\u1ef7 l\u1ec7 t\u01b0\u01a1ng \u1ee9ng kho\u1ea3ng 68% v\u00e0 27%. Th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh kho\u1ea3ng 7,4 gi\u1edd.<\/p>\n<h2>Thu\u1ed1c Zurelsavi 5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p><strong>Thu\u1ed1c <\/strong><strong>Zurelsavi 5<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng trong tr\u01b0\u1eddng h\u1ee3p ph\u00f2ng ng\u1eeba c\u00e1c bi\u1ebfn c\u1ed1 tim m\u1ea1ch, bao g\u1ed3m huy\u1ebft kh\u1ed1i, x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch, th\u01b0\u1eddng g\u1eb7p \u1edf b\u1ec7nh nh\u00e2n b\u1ecb nh\u1ed3i m\u00e1u c\u01a1 tim, \u0111au th\u1eaft ng\u1ef1c kh\u00f4ng \u1ed5n \u0111\u1ecbnh.<\/p>\n<figure id=\"attachment_122039\" aria-describedby=\"caption-attachment-122039\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-122039\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Zurelsavi-5.jpg\" alt=\"Ch\u1ec9 \u0111\u1ecbnh d\u00f9ng thu\u1ed1c Zurelsavi 5\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Zurelsavi-5.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Zurelsavi-5-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Zurelsavi-5-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Zurelsavi-5-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-122039\" class=\"wp-caption-text\">Ch\u1ec9 \u0111\u1ecbnh d\u00f9ng thu\u1ed1c Zurelsavi 5<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Zurelsavi 5<\/h2>\n<ul>\n<li>Li\u1ec1u d\u00f9ng cho ng\u01b0\u1eddi l\u1edbn: Kh\u1edfi \u0111\u1ea7u v\u1edbi li\u1ec1u n\u1ea1p 60mg duy nh\u1ea5t, sau \u0111\u00f3 s\u1eed d\u1ee5ng 10 mg\/ng\u00e0y<\/li>\n<li>Li\u1ec1u d\u00f9ng cho b\u1ec7nh nh\u00e2n tr\u00ean 75 tu\u1ed5i: kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng thu\u1ed1c Zurelsavi 5 cho nh\u00f3m b\u1ec7nh nh\u00e2n n\u00e0y<\/li>\n<li>Li\u1ec1u d\u00f9ng cho b\u1ec7nh nh\u00e2n d\u01b0\u1edbi 60kg: Kh\u1edfi \u0111\u1ea7u v\u1edbi li\u1ec1u n\u1ea1p 60mg duy nh\u1ea5t, sau \u0111\u00f3 s\u1eed d\u1ee5ng 5 mg\/ng\u00e0y<\/li>\n<li>Li\u1ec1u d\u00f9ng cho b\u1ec7nh nh\u00e2n suy gan, suy th\u1eadn: Kh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u d\u00f9ng Zurelsavi 5 cho b\u1ec7nh nh\u00e2n suy gi\u1ea3m ch\u1ee9c n\u0103ng gan, suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn.<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Zurelsavi 5 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng thu\u1ed1c Zurelsavi 5 cho b\u1ec7nh nh\u00e2n d\u1ecb \u1ee9ng v\u1edbi Prasugrel ho\u1eb7c b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c n\u00e0o trong thu\u1ed1c<\/li>\n<li>Kh\u00f4ng d\u00f9ng thu\u1ed1c cho b\u1ec7nh nh\u00e2n suy gan n\u1eb7ng, c\u00f3 ti\u1ec1n s\u1eed \u0111\u1ed9t qu\u1ef5, thi\u1ebfu m\u00e1u n\u00e3o, xu\u1ea5t huy\u1ebft<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Zurelsavi 5<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Th\u1eadn tr\u1ecdng khi d\u00f9ng thu\u1ed1c Zurelsavi 5 cho b\u1ec7nh nh\u00e2n tr\u00ean 75 tu\u1ed5i, d\u01b0\u1edbi 60kg, xu\u1ea5t huy\u1ebft \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, c\u00f3 nguy c\u01a1 t\u00e1i ph\u00e1t vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng, suy gan, \u0111ang s\u1eed d\u1ee5ng thu\u1ed1c l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u,\u2026 do c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u \u1edf b\u1ec7nh nh\u00e2n.<\/li>\n<li>T\u00ecnh tr\u1ea1ng ph\u00f9 m\u1ea1ch \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o, th\u1eadn tr\u1ecdng khi d\u00f9ng thu\u1ed1c cho b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng thienopyridine<\/li>\n<li>B\u1ec7nh nh\u00e2n nghi ng\u1edd xu\u1ea5t huy\u1ebft gi\u1ea3m ti\u1ec3u c\u1ea7u huy\u1ebft kh\u1ed1i c\u1ea7n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb k\u1ecbp th\u1eddi.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Zurelsavi 5 bao g\u1ed3m thi\u1ebfu m\u00e1u, t\u1ee5 m\u00e1u, xu\u1ea5t huy\u1ebft ti\u00eau h\u00f3a, b\u1ea7m t\u00edm, ti\u1ec3u m\u00e1u, l\u00fa l\u1eabn, qu\u00e1 m\u1eabn, ho ra m\u00e1u, ch\u1ea3y m\u00e1u sau th\u1ee7 thu\u1eadt, gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng ti\u1ec3u c\u1ea7u, t\u1ee5 m\u00e1u d\u01b0\u1edbi da, xu\u1ea5t huy\u1ebft gi\u1ea3m ti\u1ec3u c\u1ea7u huy\u1ebft kh\u1ed1i.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<table>\n<tbody>\n<tr>\n<td width=\"312\">Thu\u1ed1c<\/td>\n<td width=\"312\">T\u01b0\u01a1ng t\u00e1c<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">Wafarin<\/td>\n<td width=\"312\">Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi do l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">NSAID<\/td>\n<td width=\"312\">C\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u, th\u1eadn tr\u1ecdng khi k\u1ebft h\u1ee3p<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">Heparin<\/td>\n<td width=\"312\">C\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">Statin, thu\u1ed1c l\u00e0m t\u0103ng pH d\u1ea1 d\u00e0y<\/td>\n<td width=\"312\">L\u00e0m \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1c th\u00f4ng s\u1ed1 d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a Zurelsavi 5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Hi\u1ec7n t\u1ea1i ch\u01b0a c\u00f3 \u0111\u1ea7y \u0111\u1ee7 nghi\u00ean c\u1ee9u v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c Zurelsavi 5 cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 \u0111ang cho con b\u00fa, tham kh\u1ea3o \u00fd ki\u1ebfn c\u1ee7a b\u00e1c s\u0129 tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c Zurelsavi 5 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng ho\u1eb7c \u1ea3nh h\u01b0\u1edfng kh\u00f4ng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>S\u1eed d\u1ee5ng qu\u00e1 li\u1ec1u Zurelsavi 5 g\u00e2y k\u00e9o d\u00e0i th\u1eddi gian ch\u1ea3y m\u00e1u, t\u0103ng nguy c\u01a1 bi\u1ebfn ch\u1ee9ng ch\u1ea3y m\u00e1u. B\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb v\u00e0 h\u1ed7 tr\u1ee3 k\u1ecbp th\u1eddi, c\u00e2n nh\u1eafc truy\u1ec1n ti\u1ec3u c\u1ea7u n\u1ebfu c\u1ea7n thi\u1ebft.<\/p>\n<h2>Thu\u1ed1c Zurelsavi 5 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Thu\u1ed1c Zurelsavi 5 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>Dobesh PP. Pharmacokinetics and pharmacodynamics of prasugrel, a thienopyridine P2Y12 inhibitor. Pharmacotherapy, truy c\u1eadp ng\u00e0y 04 th\u00e1ng 06 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19698014\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/19698014\/<\/a><\/li>\n<li>Schr\u00f6r K, Siller-Matula JM, Huber K. Pharmacokinetic basis of the antiplatelet action of prasugrel. Fundam Clin Pharmacol, truy c\u1eadp ng\u00e0y 04 th\u00e1ng 06 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21895761\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/21895761\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Zurelsavi 5 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m SaVi, ph\u00f2ng ng\u1eeba c\u00e1c bi\u1ebfn c\u1ed1 tim m\u1ea1ch, bao g\u1ed3m huy\u1ebft kh\u1ed1i, x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch, th\u01b0\u1eddng g\u1eb7p \u1edf b\u1ec7nh nh\u00e2n b\u1ecb nh\u1ed3i m\u00e1u c\u01a1 tim,&#8230;<\/p>\n","protected":false},"author":1,"featured_media":122040,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-122038","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/122038","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=122038"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/122040"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=122038"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=122038"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=122038"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}