{"id":121387,"date":"2025-05-31T16:05:06","date_gmt":"2025-05-31T09:05:06","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=121387"},"modified":"2025-12-23T14:07:03","modified_gmt":"2025-12-23T07:07:03","slug":"lisiplus-hct-20-12-5","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/lisiplus-hct-20-12-5\/","title":{"rendered":"Lisiplus HCT 20\/12.5"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Lisiplus HCT 20\/12.5 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean Doanh Stellapharm &#8211; Chi nh\u00e1nh 1, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110914724 (VD-18111-12).<\/strong><\/p>\n<h2>Lisiplus HCT 20\/12.5 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Lisiplus HCT 20\/12.5<\/strong> ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li><strong>Lisinopril<\/strong>: 20mg<\/li>\n<li>Hydrochlorothiazide: 12.5mg<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110914724 (VD-18111-12)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_121388\" aria-describedby=\"caption-attachment-121388\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-121388\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/lisiplus-1.jpg\" alt=\"Lisiplus HCT 20\/12.5 \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/lisiplus-1.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/lisiplus-1-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/lisiplus-1-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/lisiplus-1-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-121388\" class=\"wp-caption-text\">Lisiplus HCT 20\/12.5 \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Lisiplus HCT 20\/12.5<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<ul>\n<li>Lisinopril: Ho\u1ea1t ch\u1ea5t n\u00e0y thu\u1ed9c nh\u00f3m thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n angiotensin (ACEI). C\u01a1 ch\u1ebf ch\u00ednh l\u00e0 ng\u0103n ch\u1eb7n h\u1ec7 th\u1ed1ng Renin-Angiotensin-Aldosterone, gi\u00fap l\u00e0m gi\u00e3n m\u1ea1ch m\u00e1u v\u00e0 gi\u1ea3m huy\u1ebft \u00e1p. Lisinopril c\u00f3 th\u1ec3 h\u1ea1 huy\u1ebft \u00e1p ngay c\u1ea3 \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 n\u1ed3ng \u0111\u1ed9 renin th\u1ea5p.<\/li>\n<li>Hydrochlorothiazide: \u0110\u00e2y l\u00e0 m\u1ed9t thu\u1ed1c l\u1ee3i ti\u1ec3u nh\u00f3m thiazide. C\u01a1 ch\u1ebf h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a thiazide ch\u01b0a \u0111\u01b0\u1ee3c hi\u1ec3u r\u00f5 ho\u00e0n to\u00e0n, nh\u01b0ng ch\u00fang l\u00e0m t\u0103ng b\u00e0i ti\u1ebft natri v\u00e0 clorua qua n\u01b0\u1edbc ti\u1ec3u. Ho\u1ea1t \u0111\u1ed9ng l\u1ee3i ti\u1ec3u n\u00e0y gi\u00e1n ti\u1ebfp l\u00e0m gi\u1ea3m th\u1ec3 t\u00edch huy\u1ebft t\u01b0\u01a1ng, t\u1eeb \u0111\u00f3 gi\u1ea3m huy\u1ebft \u00e1p. Khi k\u1ebft h\u1ee3p v\u1edbi Lisinopril, t\u00e1c d\u1ee5ng l\u1ee3i ti\u1ec3u c\u1ee7a Hydrochlorothiazide gi\u00fap t\u0103ng c\u01b0\u1eddng hi\u1ec7u qu\u1ea3 ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p v\u00e0 c\u00f3 xu h\u01b0\u1edbng b\u00f9 \u0111\u1eafp l\u1ea1i s\u1ef1 m\u1ea5t kali do thu\u1ed1c l\u1ee3i ti\u1ec3u g\u00e2y ra.<\/li>\n<\/ul>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>Lisinopril:\n<ul>\n<li>H\u1ea5p thu: Thu\u1ed1c h\u1ea5p thu ch\u1eadm v\u00e0 kh\u00f4ng ho\u00e0n to\u00e0n khi d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng, v\u1edbi \u0111\u1ed9 h\u1ea5p thu trung b\u00ecnh kho\u1ea3ng 25%. N\u1ed3ng \u0111\u1ed9 thu\u1ed1c t\u1ed1i \u0111a trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau kho\u1ea3ng 7 gi\u1edd.<\/li>\n<li>Ph\u00e2n b\u1ed1: Lisinopril kh\u00f4ng g\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng.<\/li>\n<li>Th\u1ea3i tr\u1eeb: Thu\u1ed1c \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i. Th\u1eddi gian b\u00e1n th\u1ea3i hi\u1ec7u qu\u1ea3 l\u00e0 12 gi\u1edd \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng.<\/li>\n<\/ul>\n<\/li>\n<li>Hydrochlorothiazide:\n<ul>\n<li>H\u1ea5p thu: H\u1ea5p thu kh\u00e1 nhanh qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a v\u1edbi sinh kh\u1ea3 d\u1ee5ng kho\u1ea3ng 65-70%.<\/li>\n<li>Ph\u00e2n b\u1ed1: Thu\u1ed1c c\u00f3 th\u1ec3 \u0111i qua nhau thai v\u00e0 ph\u00e2n b\u1ed1 v\u00e0o s\u1eefa m\u1eb9.<\/li>\n<li>Th\u1ea3i tr\u1eeb: \u0110\u01b0\u1ee3c b\u00e0i ti\u1ebft d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i qua n\u01b0\u1edbc ti\u1ec3u. Th\u1eddi gian b\u00e1n th\u1ea3i trong huy\u1ebft t\u01b0\u01a1ng dao \u0111\u1ed9ng t\u1eeb 5 \u0111\u1ebfn 15 gi\u1edd.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Lisiplus HCT 20\/12.5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Lisiplus HCT 20\/12.5 \u0111\u01b0\u1ee3c d\u00f9ng cho c\u00e1c tr\u01b0\u1eddng h\u1ee3p t\u0103ng huy\u1ebft \u00e1p nh\u1eb9 v\u00e0 v\u1eeba m\u00e0 li\u1ec7u ph\u00e1p \u0111\u01a1n tr\u1ecb kh\u00f4ng th\u1ec3 ki\u1ec3m so\u00e1t hi\u1ec7u qu\u1ea3.<\/p>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Lisiplus HCT 20\/12.5<\/h2>\n<ul>\n<li>Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng.<\/li>\n<li>Li\u1ec1u kh\u1edfi \u0111\u1ea7u th\u00f4ng th\u01b0\u1eddng l\u00e0 1 vi\u00ean x 1 l\u1ea7n\/ng\u00e0y, n\u00ean u\u1ed1ng v\u00e0o c\u00f9ng m\u1ed9t th\u1eddi \u0111i\u1ec3m m\u1ed7i ng\u00e0y. N\u1ebfu sau 2-4 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb m\u00e0 hi\u1ec7u qu\u1ea3 ch\u01b0a \u0111\u1ea1t \u0111\u01b0\u1ee3c, c\u00f3 th\u1ec3 t\u0103ng li\u1ec1u l\u00ean 2 vi\u00ean x 1 l\u1ea7n\/ng\u00e0y.<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Lisiplus HCT 20\/12.5 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>B\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>B\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed ph\u00f9 th\u1ea7n kinh m\u1ea1ch li\u00ean quan \u0111\u1ebfn vi\u1ec7c s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n angiotensin (ACEI) tr\u01b0\u1edbc \u0111\u00f3, ho\u1eb7c b\u1ec7nh nh\u00e2n b\u1ecb ph\u00f9 m\u1ea1ch di truy\u1ec1n\/t\u1ef1 ph\u00e1t.<\/li>\n<li>B\u1ec7nh nh\u00e2n m\u1eabn c\u1ea3m v\u1edbi c\u00e1c d\u1eabn xu\u1ea5t sulfonamide kh\u00e1c.<\/li>\n<li>B\u1ec7nh nh\u00e2n v\u00f4 ni\u1ec7u.<\/li>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai: Thu\u1ed1c ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh cho ph\u1ee5 n\u1eef c\u00f3 thai. C\u1ea7n ng\u01b0ng thu\u1ed1c ngay l\u1eadp t\u1ee9c n\u1ebfu nghi ng\u1edd c\u00f3 thai.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Lisiplus HCT 20\/12.5<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>H\u1ea1 huy\u1ebft \u00e1p v\u00e0 m\u1ea5t c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i\/d\u1ecbch: C\u00f3 th\u1ec3 x\u1ea3y ra h\u1ea1 huy\u1ebft \u00e1p tri\u1ec7u ch\u1ee9ng \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n. C\u1ea7n ki\u1ec3m tra \u0111\u1ecbnh k\u1ef3 \u0111i\u1ec7n gi\u1ea3i huy\u1ebft thanh. B\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 h\u1ea1 huy\u1ebft \u00e1p cao c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i ch\u1eb7t ch\u1ebd khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u00e0 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u. C\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng thu\u1ed1c cho b\u1ec7nh nh\u00e2n thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9 c\u01a1 tim ho\u1eb7c b\u1ec7nh m\u1ea1ch m\u00e1u n\u00e3o.<\/li>\n<li>B\u1ec7nh nh\u00e2n suy ch\u1ee9c n\u0103ng th\u1eadn: Thiazide kh\u00f4ng th\u00edch h\u1ee3p cho b\u1ec7nh nh\u00e2n suy th\u1eadn n\u1eb7ng (\u0111\u1ed9 thanh th\u1ea3i creatinine \u2264 30ml\/ph\u00fat). C\u1ea7n b\u1eaft \u0111\u1ea7u v\u1edbi li\u1ec1u th\u1ea5p v\u00e0 d\u01b0\u1edbi s\u1ef1 gi\u00e1m s\u00e1t y t\u1ebf ch\u1eb7t ch\u1ebd, theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn trong nh\u1eefng tu\u1ea7n \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb.<\/li>\n<li>B\u1ec7nh nh\u00e2n c\u00f3 b\u1ec7nh gan: Th\u1eadn tr\u1ecdng khi d\u00f9ng thiazide cho b\u1ec7nh nh\u00e2n suy ch\u1ee9c n\u0103ng gan ho\u1eb7c b\u1ec7nh gan ti\u1ebfn tri\u1ec3n, v\u00ec thay \u0111\u1ed5i nh\u1ecf trong c\u00e2n b\u1eb1ng d\u1ecbch v\u00e0 \u0111i\u1ec7n gi\u1ea3i c\u00f3 th\u1ec3 g\u00e2y h\u00f4n m\u00ea gan.<\/li>\n<li>T\u00e1c \u0111\u1ed9ng tr\u00ean chuy\u1ec3n h\u00f3a v\u00e0 n\u1ed9i ti\u1ebft:<\/li>\n<li>Thiazide c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m b\u00e0i ti\u1ebft canxi ni\u1ec7u v\u00e0 g\u00e2y t\u0103ng nh\u1eb9 canxi huy\u1ebft t\u01b0\u01a1ng. C\u1ea7n ng\u01b0ng thiazide tr\u01b0\u1edbc khi x\u00e9t nghi\u1ec7m tuy\u1ebfn c\u1eadn gi\u00e1p.<\/li>\n<li>C\u00f3 th\u1ec3 t\u0103ng n\u1ed3ng \u0111\u1ed9 cholesterol v\u00e0 triglyceride.<\/li>\n<li>Thiazide c\u00f3 th\u1ec3 l\u00e0m t\u0103ng acid uric huy\u1ebft ho\u1eb7c g\u00e2y b\u1ec7nh g\u00fat, tuy nhi\u00ean Lisinopril c\u00f3 th\u1ec3 gi\u00fap gi\u1ea3m t\u00e1c d\u1ee5ng n\u00e0y.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>Th\u01b0\u1eddng g\u1eb7p\n<ul>\n<li>Th\u1ea7n kinh: Ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, m\u1ec7t m\u1ecfi.<\/li>\n<li>H\u00f4 h\u1ea5p: Ho khan.<\/li>\n<li>Tim m\u1ea1ch: H\u1ea1 huy\u1ebft \u00e1p (bao g\u1ed3m h\u1ea1 huy\u1ebft \u00e1p th\u1ebf \u0111\u1ee9ng).<\/li>\n<li>Kh\u00e1c: Gi\u1ea3m nh\u1eb9 hemoglobin v\u00e0 th\u1ec3 t\u00edch huy\u1ebft c\u1ea7u \u0111\u1eb7c.<\/li>\n<\/ul>\n<\/li>\n<li>\u00cdt x\u1ea3y ra h\u01a1n\n<ul>\n<li>Ti\u00eau h\u00f3a: Ti\u00eau ch\u1ea3y, bu\u1ed3n n\u00f4n, n\u00f4n.<\/li>\n<li>Da: Ph\u00e1t ban.<\/li>\n<li>Kh\u00e1c: Kh\u00f4 mi\u1ec7ng, b\u1ec7nh g\u00fat (th\u1ed1ng phong), \u0111\u00e1nh tr\u1ed1ng ng\u1ef1c, n\u1eb7ng ng\u1ef1c, chu\u1ed9t r\u00fat, d\u1ecb c\u1ea3m, suy nh\u01b0\u1ee3c, b\u1ea5t l\u1ef1c. C\u00f3 th\u1ec3 g\u00e2y t\u0103ng \u0111\u01b0\u1eddng huy\u1ebft, t\u0103ng acid uric huy\u1ebft, t\u0103ng ho\u1eb7c gi\u1ea3m kali huy\u1ebft.<\/li>\n<\/ul>\n<\/li>\n<li>Hi\u1ebfm g\u1eb7p: T\u0103ng men gan, vi\u00eam t\u1ee5y, m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t.<\/li>\n<li>C\u00e1c x\u00e9t nghi\u1ec7m\n<ul>\n<li>T\u0103ng nh\u1eb9 v\u00e0 tho\u00e1ng qua ure, nitrogen m\u00e1u, creatinine huy\u1ebft thanh c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ghi nh\u1eadn \u1edf b\u1ec7nh nh\u00e2n kh\u00f4ng c\u00f3 ti\u1ec1n s\u1eed suy th\u1eadn.<\/li>\n<li>\u1ee8c ch\u1ebf t\u1ee7y x\u01b0\u01a1ng (thi\u1ebfu m\u00e1u, gi\u1ea3m ti\u1ec3u c\u1ea7u, gi\u1ea3m b\u1ea1ch c\u1ea7u) \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o.<\/li>\n<\/ul>\n<\/li>\n<li>Ph\u00f9 th\u1ea7n kinh m\u1ea1ch c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n \u1edf m\u1eb7t, t\u1ee9 chi, m\u00f4i, l\u01b0\u1ee1i, thanh m\u00f4n v\u00e0\/ho\u1eb7c thanh qu\u1ea3n, m\u1eb7c d\u00f9 r\u1ea5t hi\u1ebfm. M\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p hi\u1ebfm h\u01a1n n\u1eefa l\u00e0 ph\u00f9 m\u1ea1ch ti\u00eau h\u00f3a. M\u1ed9t s\u1ed1 bi\u1ec3u hi\u1ec7n ph\u1ee9c h\u1ee3p c\u00f3 th\u1ec3 bao g\u1ed3m s\u1ed1t, vi\u00eam m\u1ea1ch, \u0111au c\u01a1, \u0111au kh\u1edbp\/vi\u00eam kh\u1edbp, x\u00e9t nghi\u1ec7m ANA d\u01b0\u01a1ng t\u00ednh, t\u0103ng t\u1ed1c \u0111\u1ed9 l\u1eafng m\u00e1u (ESR), t\u0103ng b\u1ea1ch c\u1ea7u \u01b0a acid, ph\u00e1t ban, nh\u1ea1y c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>C\u00e1c thu\u1ed1c l\u00e0m t\u0103ng kali huy\u1ebft thanh: Th\u1eadn tr\u1ecdng khi d\u00f9ng \u0111\u1ed3ng th\u1eddi, \u0111\u1eb7c bi\u1ec7t v\u1edbi thu\u1ed1c l\u1ee3i ti\u1ec3u gi\u1eef kali ho\u1eb7c c\u00e1c ch\u1ea5t thay th\u1ebf mu\u1ed1i ch\u1ee9a kali, v\u00ec c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn t\u0103ng kali huy\u1ebft thanh \u0111\u00e1ng k\u1ec3.<\/li>\n<li>C\u00e1c t\u00e1c nh\u00e2n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ho\u1ea1t t\u00ednh giao c\u1ea3m: C\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng. Thu\u1ed1c ch\u1eb9n beta-adrenergic c\u00f3 th\u1ec3 t\u0103ng c\u01b0\u1eddng t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a Lisinopril.<\/li>\n<li>Indomethacin: C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a Lisinopril.<\/li>\n<li>Lithium: Kh\u00f4ng n\u00ean d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi thu\u1ed1c l\u1ee3i ti\u1ec3u ho\u1eb7c ACEI v\u00ec c\u00f3 th\u1ec3 gi\u1ea3m \u0111\u1ed9 thanh th\u1ea3i lithium qua th\u1eadn v\u00e0 t\u0103ng nguy c\u01a1 \u0111\u1ed9c t\u00ednh lithium.<\/li>\n<li>Corticosteroid (ACTH): T\u0103ng nguy c\u01a1 m\u1ea5t \u0111i\u1ec7n gi\u1ea3i, \u0111\u1eb7c bi\u1ec7t h\u1ea1 kali huy\u1ebft.<\/li>\n<li>Thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00f4ng steroid (NSAID): \u1ede b\u1ec7nh nh\u00e2n suy th\u1eadn, d\u00f9ng \u0111\u1ed3ng th\u1eddi Lisinopril v\u1edbi NSAID c\u00f3 th\u1ec3 l\u00e0m suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn.<\/li>\n<li>Tubocurarine: Thiazide c\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u0111\u00e1p \u1ee9ng c\u1ee7a Tubocurarine.<\/li>\n<li>Insulin: Thiazide c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m dung n\u1ea1p glucose, c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u insulin ho\u1eb7c c\u00e1c thu\u1ed1c tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng kh\u00e1c.<\/li>\n<li>R\u01b0\u1ee3u, Barbiturate, Narcotic: S\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a thiazide c\u00f3 th\u1ec3 g\u00e2y h\u1ea1 huy\u1ebft \u00e1p th\u1ebf \u0111\u1ee9ng.<\/li>\n<li>Thu\u1ed1c t\u0103ng \u00e1p amine: Thiazide c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m \u0111\u00e1p \u1ee9ng v\u1edbi c\u00e1c thu\u1ed1c t\u0103ng \u00e1p amine.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<ul>\n<li>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u1edbi ph\u1ee5 n\u1eef c\u00f3 thai.<\/li>\n<li>Ph\u1ee5 n\u1eef cho con b\u00fa: Hydrochlorothiazide b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9, c\u00f2n Lisinopril th\u00ec ch\u01b0a r\u00f5. C\u1ea7n c\u00e2n nh\u1eafc l\u1ee3i \u00edch\/nguy c\u01a1 v\u00e0 quy\u1ebft \u0111\u1ecbnh ng\u1eebng thu\u1ed1c ho\u1eb7c ng\u1eebng cho con b\u00fa.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c: Thu\u1ed1c c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh \u0111\u1ebfn kh\u1ea3 n\u0103ng n\u00e0y, t\u01b0\u01a1ng t\u1ef1 nh\u01b0 c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p kh\u00e1c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Hi\u1ec7n ch\u01b0a c\u00f3 th\u00f4ng tin c\u1ee5 th\u1ec3 v\u1ec1 \u0111i\u1ec1u tr\u1ecb qu\u00e1 li\u1ec1u Lisiplus HCT 20\/12.5. Trong tr\u01b0\u1eddng h\u1ee3p n\u00e0y, c\u1ea7n \u0111i\u1ec1u tr\u1ecb theo tri\u1ec7u ch\u1ee9ng v\u00e0 h\u1ed7 tr\u1ee3. N\u00ean ng\u01b0ng d\u00f9ng thu\u1ed1c v\u00e0 theo d\u00f5i b\u1ec7nh nh\u00e2n ch\u1eb7t ch\u1ebd. C\u00e1c bi\u1ec7n ph\u00e1p c\u00f3 th\u1ec3 bao g\u1ed3m g\u00e2y n\u00f4n ho\u1eb7c r\u1eeda d\u1ea1 d\u00e0y, v\u00e0 \u0111i\u1ec1u ch\u1ec9nh t\u00ecnh tr\u1ea1ng m\u1ea5t n\u01b0\u1edbc, m\u1ea5t c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i, ho\u1eb7c h\u1ea1 huy\u1ebft \u00e1p.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Lisiplus HCT 20\/12.5<\/h2>\n<p>Thu\u1ed1c<a href=\"https:\/\/vnras.com\/drug\/umenohct-20-125\/\"> UmenoHCT 20\/12,5<\/a> ch\u1ee9a th\u00e0nh ph\u1ea7n Lisinopril (d\u01b0\u1edbi d\u1ea1ng Lisinopril dihydrat) 20mg, Hydroclorothiazid 12,5mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m SaVi, d\u00f9ng cho b\u1ec7nh nh\u00e2n t\u0103ng huy\u1ebft \u00e1p m\u1ee9c \u0111\u1ed9 nh\u1eb9 v\u00e0 trung b\u00ecnh.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Brandon J Sonn, Jessica L Saben, Glenn McWilliams, Shelby K Shelton, Hania K Flaten, Angelo D&#8217;Alessandro, Andrew A Monte. Predicting response to lisinopril in treating hypertension: a pilot study, truy c\u1eadp ng\u00e0y 31 th\u00e1ng 05 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31583478\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/31583478\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Lisiplus HCT 20\/12.5 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean Doanh Stellapharm &#8211; Chi nh\u00e1nh 1, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110914724 (VD-18111-12).<\/p>\n","protected":false},"author":1,"featured_media":121389,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-121387","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/121387","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=121387"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/121389"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=121387"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=121387"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=121387"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}