{"id":120531,"date":"2025-05-27T14:28:15","date_gmt":"2025-05-27T07:28:15","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=120531"},"modified":"2025-07-24T13:13:27","modified_gmt":"2025-07-24T06:13:27","slug":"freclovir-400","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/freclovir-400\/","title":{"rendered":"FRECLOVIR 400"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>FRECLOVIR 400 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Fremed, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-36126-22.<\/strong><\/p>\n<h2>FRECLOVIR 400 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Freclovir 400 l\u00e0 thu\u1ed1c vi\u00ean n\u00e9n ch\u1ee9a Acyclovir 400mg.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-36126-22<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_120532\" aria-describedby=\"caption-attachment-120532\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-120532\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Frecovir-4.jpg\" alt=\"FRECLOVIR 400 \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m virus Herpes\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Frecovir-4.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Frecovir-4-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Frecovir-4-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Frecovir-4-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-120532\" class=\"wp-caption-text\">FRECLOVIR 400 \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m virus Herpes<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c FRECLOVIR 400<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<ul>\n<li>Acyclovir l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c kh\u00e1ng virus t\u1ed5ng h\u1ee3p, c\u00f3 c\u1ea5u tr\u00fac t\u01b0\u01a1ng t\u1ef1 nucleoside purin. N\u00f3 th\u1ec3 hi\u1ec7n kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf m\u1ea1nh m\u1ebd virus Herpes simplex lo\u1ea1i 1 (HSV-1), lo\u1ea1i 2 (HSV-2) v\u00e0 virus Varicella-zoster (VZV) c\u1ea3 trong \u1ed1ng nghi\u1ec7m (in vitro) v\u00e0 tr\u00ean c\u01a1 th\u1ec3 s\u1ed1ng (in vivo).<\/li>\n<li>Kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf virus c\u1ee7a Acyclovir c\u00f3 t\u00ednh ch\u1ecdn l\u1ecdc cao nh\u1edd \u00e1i l\u1ef1c \u0111\u1eb7c bi\u1ec7t c\u1ee7a n\u00f3 v\u1edbi enzyme thymidine kinase (TK) do virus HSV v\u00e0 VZV t\u1ea1o ra. Enzyme n\u00e0y \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong vi\u1ec7c bi\u1ebfn \u0111\u1ed5i Acyclovir:\n<ul>\n<li>Acyclovir \u0111\u01b0\u1ee3c enzyme TK c\u1ee7a virus phosphoryl h\u00f3a th\u00e0nh acyclovir monophosphate.<\/li>\n<li>Ti\u1ebfp theo, acyclovir monophosphate \u0111\u01b0\u1ee3c c\u00e1c enzyme trong t\u1ebf b\u00e0o chuy\u1ec3n \u0111\u1ed5i th\u00e0nh diphosphate (nh\u1edd guanylate kinase) v\u00e0 cu\u1ed1i c\u00f9ng l\u00e0 triphosphate.<\/li>\n<\/ul>\n<\/li>\n<li>Acyclovir triphosphate l\u00e0 d\u1ea1ng c\u00f3 ho\u1ea1t t\u00ednh, can thi\u1ec7p v\u00e0o qu\u00e1 tr\u00ecnh sao ch\u00e9p DNA c\u1ee7a virus Herpes theo ba c\u01a1 ch\u1ebf ch\u00ednh:\n<ul>\n<li>\u1ee8c ch\u1ebf c\u1ea1nh tranh: C\u1ea1nh tranh v\u1edbi DNA polymerase c\u1ee7a virus, l\u00e0m gi\u00e1n \u0111o\u1ea1n qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p DNA.<\/li>\n<li>K\u1ebft th\u00fac chu\u1ed7i: G\u1eafn v\u00e0o chu\u1ed7i DNA c\u1ee7a virus \u0111ang \u0111\u01b0\u1ee3c t\u1ed5ng h\u1ee3p, l\u00e0m d\u1eebng qu\u00e1 tr\u00ecnh sao ch\u00e9p.<\/li>\n<li>B\u1ea5t ho\u1ea1t enzyme: L\u00e0m m\u1ea5t ho\u1ea1t t\u00ednh c\u1ee7a DNA polymerase c\u1ee7a virus.<\/li>\n<\/ul>\n<\/li>\n<li>Acyclovir c\u00f3 ho\u1ea1t t\u00ednh kh\u00e1ng HSV m\u1ea1nh h\u01a1n so v\u1edbi kh\u00e1ng VZV do qu\u00e1 tr\u00ecnh phosphoryl h\u00f3a b\u1edfi enzyme TK c\u1ee7a virus HSV hi\u1ec7u qu\u1ea3 h\u01a1n.<\/li>\n<\/ul>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu: Khi d\u00f9ng qua \u0111\u01b0\u1eddng u\u1ed1ng, sinh kh\u1ea3 d\u1ee5ng c\u1ee7a Acyclovir t\u01b0\u01a1ng \u0111\u1ed1i th\u1ea5p, kho\u1ea3ng 20% (dao \u0111\u1ed9ng t\u1eeb 15% \u0111\u1ebfn 30%). \u0110i\u1ec1u \u0111\u00e1ng ch\u00fa \u00fd l\u00e0 s\u1ef1 h\u1ea5p thu c\u1ee7a thu\u1ed1c kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi th\u1ee9c \u0103n. N\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u1ec9nh sau kho\u1ea3ng 1,5 \u0111\u1ebfn 2 gi\u1edd.<\/li>\n<li>Ph\u00e2n b\u1ed1: Acyclovir ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i kh\u1eafp c\u00e1c d\u1ecbch c\u01a1 th\u1ec3 v\u00e0 c\u00e1c c\u01a1 quan, bao g\u1ed3m n\u00e3o, th\u1eadn, ph\u1ed5i, gan, l\u00e1 l\u00e1ch, ru\u1ed9t, c\u01a1 b\u1eafp, t\u1eed cung, ni\u00eam m\u1ea1c, d\u1ecbch \u00e2m \u0111\u1ea1o, n\u01b0\u1edbc m\u1eaft, th\u1ee7y d\u1ecbch, tinh d\u1ecbch v\u00e0 d\u1ecbch n\u00e3o t\u1ee7y. T\u1ef7 l\u1ec7 li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng c\u1ee7a Acyclovir th\u1ea5p, ch\u1ec9 t\u1eeb 9% \u0111\u1ebfn 33%.<\/li>\n<li>Chuy\u1ec3n h\u00f3a v\u00e0 th\u1ea3i tr\u1eeb: M\u1ed9t l\u01b0\u1ee3ng nh\u1ecf Acyclovir \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a t\u1ea1i gan, ph\u1ea7n l\u1edbn (kho\u1ea3ng 30% \u0111\u1ebfn 90% li\u1ec1u d\u00f9ng) \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua th\u1eadn d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i th\u00f4ng qua b\u00e0i ti\u1ebft ch\u1ee7 \u0111\u1ed9ng \u1edf \u1ed1ng th\u1eadn. Th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a thu\u1ed1c kho\u1ea3ng 3 gi\u1edd \u1edf ng\u01b0\u1eddi l\u1edbn, 2-3 gi\u1edd \u1edf tr\u1ebb em, v\u00e0 kho\u1ea3ng 4 gi\u1edd \u1edf tr\u1ebb s\u01a1 sinh.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c FRECLOVIR 400 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Freclovir 400 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng c\u00e1c b\u1ec7nh l\u00fd do virus g\u00e2y ra:<\/p>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb:\n<ul>\n<li>B\u1ec7nh th\u1ee7y \u0111\u1eadu (nhi\u1ec5m Varicella): Gi\u00fap l\u00e0m gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng v\u00e0 r\u00fat ng\u1eafn th\u1eddi gian b\u1ec7nh.<\/li>\n<li>B\u1ec7nh Zona (Herpes zoster): H\u1ed7 tr\u1ee3 \u0111i\u1ec1u tr\u1ecb c\u00e1c tr\u01b0\u1eddng h\u1ee3p zona c\u1ea5p t\u00ednh, zona m\u1eaft v\u00e0 vi\u00eam ph\u1ed5i do Herpes zoster.<\/li>\n<li>Nhi\u1ec5m Herpes simplex: Bao g\u1ed3m nhi\u1ec5m Herpes simplex \u1edf ni\u00eam m\u1ea1c (k\u1ec3 c\u1ea3 c\u01a1 quan sinh d\u1ee5c) v\u00e0 da, c\u1ea3 kh\u1edfi ph\u00e1t v\u00e0 t\u00e1i ph\u00e1t. (Kh\u00f4ng \u00e1p d\u1ee5ng cho tr\u1ebb b\u1ecb suy gi\u1ea3m mi\u1ec5n d\u1ecbch n\u1eb7ng ho\u1eb7c tr\u1ebb s\u01a1 sinh nhi\u1ec5m HSV n\u1eb7ng).<\/li>\n<li>Vi\u00eam n\u00e3o Herpes simplex.<\/li>\n<\/ul>\n<\/li>\n<li>D\u1ef1 ph\u00f2ng:\n<ul>\n<li>Ng\u01b0\u1eddi c\u00f3 mi\u1ec5n d\u1ecbch b\u00ecnh th\u01b0\u1eddng: Ng\u0103n ng\u1eeba t\u00e1i nhi\u1ec5m Herpes simplex.<\/li>\n<li>Ng\u01b0\u1eddi c\u00f3 mi\u1ec5n d\u1ecbch suy gi\u1ea3m: Ph\u00f2ng ng\u1eeba nhi\u1ec5m Herpes simplex, bao g\u1ed3m c\u1ea3 ng\u01b0\u1eddi c\u1ea5y gh\u00e9p n\u1ed9i t\u1ea1ng ph\u1ea3i d\u00f9ng thu\u1ed1c \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch, ng\u01b0\u1eddi nhi\u1ec5m HIV, ho\u1eb7c ng\u01b0\u1eddi \u0111ang h\u00f3a tr\u1ecb li\u1ec7u.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c FRECLOVIR 400<\/h2>\n<p>Freclovir 400 \u0111\u01b0\u1ee3c d\u00f9ng qua \u0111\u01b0\u1eddng u\u1ed1ng. Li\u1ec1u l\u01b0\u1ee3ng c\u1ee5 th\u1ec3 ph\u1ee5 thu\u1ed9c v\u00e0o t\u00ecnh tr\u1ea1ng b\u1ec7nh v\u00e0 \u0111\u1ed1i t\u01b0\u1ee3ng s\u1eed d\u1ee5ng:<\/p>\n<h3>Li\u1ec1u d\u00f9ng cho ng\u01b0\u1eddi l\u1edbn<\/h3>\n<ul>\n<li>Nhi\u1ec5m virus Herpes simplex:\n<ul>\n<li>Li\u1ec1u th\u00f4ng th\u01b0\u1eddng: 200mg (n\u1eeda vi\u00ean) m\u1ed7i 4 gi\u1edd, d\u00f9ng 5 l\u1ea7n\/ng\u00e0y. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb 5 ng\u00e0y, c\u00f3 th\u1ec3 k\u00e9o d\u00e0i n\u1ebfu tri\u1ec7u ch\u1ee9ng ban \u0111\u1ea7u n\u1eb7ng.<\/li>\n<li>Ng\u01b0\u1eddi suy gi\u1ea3m mi\u1ec5n d\u1ecbch: C\u00f3 th\u1ec3 t\u0103ng li\u1ec1u l\u00ean 400mg (1 vi\u00ean) m\u1ed7i l\u1ea7n, d\u00f9ng 5 l\u1ea7n\/ng\u00e0y.<\/li>\n<\/ul>\n<\/li>\n<li>Nhi\u1ec5m Herpes zoster (b\u1ec7nh Zona) v\u00e0 th\u1ee7y \u0111\u1eadu:\n<ul>\n<li>800mg (2 vi\u00ean) m\u1ed7i 4 gi\u1edd, d\u00f9ng 5 l\u1ea7n\/ng\u00e0y. N\u00ean b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb trong v\u00f2ng 24 gi\u1edd sau khi ph\u00e1t ban v\u00e0 k\u00e9o d\u00e0i 7 ng\u00e0y.<\/li>\n<li>Ng\u01b0\u1eddi suy gi\u1ea3m mi\u1ec5n d\u1ecbch n\u1eb7ng: C\u1ea7n c\u00e2n nh\u1eafc s\u1eed d\u1ee5ng d\u1ea1ng ti\u00eam t\u0129nh m\u1ea1ch.<\/li>\n<\/ul>\n<\/li>\n<li>Ph\u00f2ng ng\u1eeba t\u00e1i nhi\u1ec5m Herpes simplex \u1edf ng\u01b0\u1eddi mi\u1ec5n d\u1ecbch b\u00ecnh th\u01b0\u1eddng: 400mg (1 vi\u00ean) x 2 l\u1ea7n\/ng\u00e0y, c\u00e1ch nhau 12 gi\u1edd.<\/li>\n<li>Ph\u00f2ng nhi\u1ec5m Herpes simplex \u1edf b\u1ec7nh nh\u00e2n suy gi\u1ea3m mi\u1ec5n d\u1ecbch: 200mg (n\u1eeda vi\u00ean) m\u1ed7i 6 gi\u1edd, d\u00f9ng 4 l\u1ea7n\/ng\u00e0y, ho\u1eb7c 400mg (1 vi\u00ean) m\u1ed7i 6 gi\u1edd, d\u00f9ng 4 l\u1ea7n\/ng\u00e0y.<\/li>\n<\/ul>\n<h3>Li\u1ec1u d\u00f9ng cho tr\u1ebb em<\/h3>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng nhi\u1ec5m Herpes simplex \u1edf tr\u1ebb c\u00f3 mi\u1ec5n d\u1ecbch k\u00e9m:\n<ul>\n<li>Tr\u1ebb tr\u00ean 2 tu\u1ed5i: Li\u1ec1u d\u00f9ng t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh.<\/li>\n<li>Tr\u1ebb d\u01b0\u1edbi 2 tu\u1ed5i: B\u1eb1ng 1\/2 li\u1ec1u ng\u01b0\u1eddi l\u1edbn.<\/li>\n<\/ul>\n<\/li>\n<li>Nhi\u1ec5m Varicella (th\u1ee7y \u0111\u1eadu):\n<ul>\n<li>Tr\u1ebb tr\u00ean 6 tu\u1ed5i: 800mg (2 vi\u00ean) x 4 l\u1ea7n\/ng\u00e0y.<\/li>\n<li>Tr\u1ebb 2 &#8211; 5 tu\u1ed5i: 400mg (1 vi\u00ean) x 4 l\u1ea7n\/ng\u00e0y.<\/li>\n<li>Tr\u1ebb d\u01b0\u1edbi 2 tu\u1ed5i: 200mg (n\u1eeda vi\u00ean) x 4 l\u1ea7n\/ng\u00e0y.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h3>Li\u1ec1u d\u00f9ng cho ng\u01b0\u1eddi suy th\u1eadn<\/h3>\n<p>C\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u d\u1ef1a tr\u00ean \u0111\u1ed9 thanh th\u1ea3i creatinin:<\/p>\n<ul>\n<li>\u0110\u1ed9 thanh th\u1ea3i creatinin 10 &#8211; 25 ml\/ph\u00fat: U\u1ed1ng 1 l\u1ea7n m\u1ed7i 8 gi\u1edd.<\/li>\n<li>\u0110\u1ed9 thanh th\u1ea3i creatinin d\u01b0\u1edbi 10 ml\/ph\u00fat: U\u1ed1ng 1 l\u1ea7n m\u1ed7i 12 gi\u1edd.<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c FRECLOVIR 400 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Freclovir 400 cho ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed m\u1eabn c\u1ea3m ho\u1eb7c d\u1ecb \u1ee9ng v\u1edbi Acyclovir ho\u1eb7c Valaciclovir.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c FRECLOVIR 400<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>C\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u cho ng\u01b0\u1eddi suy th\u1eadn v\u00e0 ng\u01b0\u1eddi cao tu\u1ed5i (do ch\u1ee9c n\u0103ng th\u1eadn suy gi\u1ea3m). Tr\u00e1nh d\u00f9ng l\u1eb7p l\u1ea1i ho\u1eb7c \u0111i\u1ec1u tr\u1ecb k\u00e9o d\u00e0i kh\u00f4ng c\u1ea7n thi\u1ebft.<\/li>\n<li>Kh\u00f4ng n\u00ean d\u00f9ng \u0111\u1ed3ng th\u1eddi Freclovir 400 v\u1edbi c\u00e1c thu\u1ed1c c\u00f3 \u0111\u1ed9c t\u00ednh tr\u00ean th\u1eadn \u0111\u1ec3 tr\u00e1nh l\u00e0m t\u0103ng nguy c\u01a1 suy th\u1eadn.<\/li>\n<li>V\u1edbi li\u1ec1u cao, c\u1ea7n duy tr\u00ec \u0111\u1ee7 l\u01b0\u1ee3ng n\u01b0\u1edbc u\u1ed1ng h\u00e0ng ng\u00e0y \u0111\u1ec3 ph\u00f2ng ng\u1eeba ng\u1ed9 \u0111\u1ed9c th\u1eadn.<\/li>\n<li>\u1ede ng\u01b0\u1eddi suy gi\u1ea3m mi\u1ec5n d\u1ecbch, vi\u1ec7c d\u00f9ng thu\u1ed1c k\u00e9o d\u00e0i c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn s\u1ef1 ch\u1ecdn l\u1ecdc c\u00e1c ch\u1ee7ng virus kh\u00e1ng thu\u1ed1c.<\/li>\n<li>\u0110\u1ed1i v\u1edbi tr\u1ebb nh\u1ecf, ch\u1ec9 n\u00ean d\u00f9ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m Herpes simplex \u1edf ni\u00eam m\u1ea1c v\u00e0 da kh\u00f4ng nghi\u00eam tr\u1ecdng.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>Th\u01b0\u1eddng g\u1eb7p: Ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, ng\u1ee9a, ph\u00e1t ban, s\u1ed1t, m\u1ec7t m\u1ecfi.<\/li>\n<li>\u00cdt g\u1eb7p: M\u00e0y \u0111ay, r\u1ee5ng t\u00f3c.<\/li>\n<li>Hi\u1ebfm g\u1eb7p: Ph\u00f9 m\u1ea1ch, t\u0103ng men gan, ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7, kh\u00f3 th\u1edf.<\/li>\n<li>R\u1ea5t hi\u1ebfm g\u1eb7p: Suy th\u1eadn c\u1ea5p, gi\u1ea3m ti\u1ec3u c\u1ea7u, gi\u1ea3m b\u1ea1ch c\u1ea7u, vi\u00eam da, vi\u00eam gan, lo\u1ea1n th\u1ea7n, \u1ea3o gi\u00e1c, co gi\u1eadt, lo\u1ea1n v\u1eadn ng\u00f4n, l\u00fa l\u1eabn, h\u00f4n m\u00ea, k\u00edch \u0111\u1ed9ng, b\u1ec7nh n\u00e3o, m\u1ea5t \u0111i\u1ec1u h\u00f2a, ng\u1ee7 g\u00e0, run.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Freclovir 400 c\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi m\u1ed9t s\u1ed1 thu\u1ed1c kh\u00e1c:<\/p>\n<ul>\n<li>Cimetidine v\u00e0 Probenecid: C\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Acyclovir trong m\u00e1u do c\u1ea1nh tranh \u0111\u00e0o th\u1ea3i qua th\u1eadn.<\/li>\n<li>Zidovudine: D\u00f9ng \u0111\u1ed3ng th\u1eddi c\u00f3 th\u1ec3 g\u00e2y t\u0103ng \u0111\u1ed9c t\u00ednh tr\u00ean th\u1ea7n kinh.<\/li>\n<li>Methotrexate: C\u1ea7n th\u1eadn tr\u1ecdng do c\u00f3 th\u1ec3 t\u0103ng nguy c\u01a1 \u0111\u1ed9c th\u1eadn.<\/li>\n<li>Theophylline: C\u00f3 th\u1ec3 l\u00e0m t\u0103ng di\u1ec7n t\u00edch d\u01b0\u1edbi \u0111\u01b0\u1eddng cong (AUC) c\u1ee7a Theophylline.<\/li>\n<li>Amphotericin B v\u00e0 Ketoconazole: C\u00f3 th\u1ec3 l\u00e0m t\u0103ng hi\u1ec7u l\u1ef1c kh\u00e1ng virus c\u1ee7a Acyclovir.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<ul>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai: Ch\u1ec9 n\u00ean s\u1eed d\u1ee5ng Freclovir 400 khi l\u1ee3i \u00edch \u0111i\u1ec1u tr\u1ecb cho m\u1eb9 v\u01b0\u1ee3t tr\u1ed9i so v\u1edbi r\u1ee7i ro ti\u1ec1m \u1ea9n cho thai nhi. Hi\u1ec7n ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u an to\u00e0n \u0111\u1ea7y \u0111\u1ee7, nh\u01b0ng c\u00e1c nghi\u00ean c\u1ee9u tr\u00ean s\u1ed1 l\u01b0\u1ee3ng h\u1ea1n ch\u1ebf ph\u1ee5 n\u1eef mang thai ch\u01b0a ghi nh\u1eadn s\u1ef1 t\u0103ng t\u1ea7n su\u1ea5t d\u1ecb t\u1eadt ho\u1eb7c \u1ea3nh h\u01b0\u1edfng c\u1ee7a thu\u1ed1c \u0111\u1ebfn thai nhi.<\/li>\n<li>Ph\u1ee5 n\u1eef cho con b\u00fa: Thu\u1ed1c b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9. C\u1ea7n th\u1eadn tr\u1ecdng v\u00e0 ch\u1ec9 s\u1eed d\u1ee5ng khi c\u00f3 ch\u1ec9 \u0111\u1ecbnh r\u00f5 r\u00e0ng t\u1eeb b\u00e1c s\u0129.<\/li>\n<\/ul>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Qu\u00e1 li\u1ec1u Freclovir 400 th\u01b0\u1eddng g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng b\u1ea5t l\u1ee3i tr\u00ean th\u1ea7n kinh (nh\u01b0 l\u00fa l\u1eabn, \u0111au \u0111\u1ea7u) ho\u1eb7c bu\u1ed3n n\u00f4n, n\u00f4n. X\u1eed tr\u00ed b\u1eb1ng c\u00e1ch \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng, ho\u1eb7c c\u00e2n nh\u1eafc th\u1ea9m t\u00e1ch m\u00e1u trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p suy th\u1eadn.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c FRECLOVIR 400<\/h2>\n<p><a href=\"https:\/\/vnras.com\/drug\/acyclovir-400-vidipha\/\">Acyclovir 400 Vidipha<\/a> c\u00f9ng th\u00e0nh ph\u1ea7n, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Trung \u01b0\u01a1ng VIDIPHA, \u0111i\u1ec1u tr\u1ecb th\u1ee7y \u0111\u1eadu, zona th\u1ea7n kinh.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Maud Maillard, Li Gong, Rina Nishii, Jun J Yang, Michelle Whirl-Carrillo, Teri E Klein. PharmGKB summary: acyclovir\/ganciclovir pathway, truy c\u1eadp ng\u00e0y 26 th\u00e1ng 05 n\u0103m 2025 t\u1eeb\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35665708\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/35665708\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c FRECLOVIR 400 l\u00e0 thu\u1ed1c vi\u00ean n\u00e9n ch\u1ee9a Acyclovir 400mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Fremed, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-36126-22.<\/p>\n","protected":false},"author":1,"featured_media":120533,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-120531","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/120531","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=120531"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/120533"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=120531"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=120531"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=120531"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}