Esomeprazol\u2026\u2026\u2026\u2026\u2026\u2026\u2026..40 mg<\/p>\n
D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean nang bao tan trong ru\u1ed9t<\/p>\n
Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: VD-22917-15<\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n
Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n
H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n
T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Ezdixum 40<\/h2>\nC\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n
Esomeprazole l\u00e0 1 d\u1ea1ng \u0111\u1ed3ng ph\u00e2n S c\u1ee7a ho\u1ea1t ch\u1ea5t omeprazole, c\u00f3 kh\u1ea3 n\u0103ng ch\u1ecdn l\u1ecdc g\u1eafn v\u00e0o enzyme H+\/K+-ATPase t\u1ea1i t\u1ebf b\u00e0o th\u00e0nh c\u1ee7a d\u1ea1 d\u00e0y. Qua \u0111\u00f3, thu\u1ed1c ng\u0103n ch\u1eb7n giai \u0111o\u1ea1n cu\u1ed1i c\u00f9ng trong qu\u00e1 tr\u00ecnh ti\u1ebft acid, l\u00e0m gi\u1ea3m c\u1ea3 ti\u1ebft acid c\u01a1 b\u1ea3n v\u00e0 do k\u00edch th\u00edch. Nh\u1edd ho\u1ea1t t\u00ednh n\u00e0y, Ezdixum 40 gi\u00fap l\u00e0m d\u1ecbu c\u00e1c tri\u1ec7u ch\u1ee9ng v\u00e0 h\u1ed7 tr\u1ee3 l\u00e0m l\u00e0nh ni\u00eam m\u1ea1c b\u1ecb t\u1ed5n th\u01b0\u01a1ng.<\/p>\n
\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n
H\u1ea5p thu: Sau khi u\u1ed1ng, esomeprazole \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh ch\u00f3ng v\u1edbi n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau kho\u1ea3ng t\u1eeb 1 \u0111\u1ebfn 2 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng c\u1ee7a thu\u1ed1c thay \u0111\u1ed5i t\u00f9y theo li\u1ec1u, t\u0103ng l\u00ean khi d\u00f9ng li\u1ec1u cao ho\u1eb7c s\u1eed d\u1ee5ng nhi\u1ec1u ng\u00e0y li\u00ean ti\u1ebfp. Th\u1ee9c \u0103n c\u00f3 th\u1ec3 l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh h\u1ea5p thu nh\u01b0ng kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb.<\/p>\n
Ph\u00e2n b\u1ed1: T\u1ef7 l\u1ec7 esomeprazole g\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t kho\u1ea3ng 97%. Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 \u01b0\u1edbc t\u00ednh v\u00e0o kho\u1ea3ng 16 l\u00edt, cho th\u1ea5y thu\u1ed1c ph\u00e2n b\u1ed1 ch\u1ee7 y\u1ebfu trong d\u1ecbch c\u01a1 th\u1ec3 v\u00e0 c\u00e1c m\u00f4 gi\u00e0u m\u1ea1ch m\u00e1u.<\/p>\n
Chuy\u1ec3n h\u00f3a: Thu\u1ed1c chuy\u1ec3n h\u00f3a g\u1ea7n nh\u01b0 ho\u00e0n to\u00e0n \u1edf gan th\u00f4ng qua h\u1ec7 enzyme cytochrome P450, ch\u1ee7 y\u1ebfu l\u00e0 CYP2C19. Qu\u00e1 tr\u00ecnh n\u00e0y t\u1ea1o ra c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00f4ng c\u00f2n ho\u1ea1t t\u00ednh. M\u1ed9t ph\u1ea7n nh\u1ecf thu\u1ed1c c\u00f2n \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a b\u1edfi CYP3A4 th\u00e0nh d\u1ea1ng sulfone. \u1ede m\u1ed9t s\u1ed1 ng\u01b0\u1eddi chuy\u1ec3n h\u00f3a ch\u1eadm (nh\u1ea5t l\u00e0 ng\u01b0\u1eddi ch\u00e2u \u00c1 thi\u1ebfu men CYP2C19), n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00e1u c\u00f3 th\u1ec3 cao h\u01a1n b\u00ecnh th\u01b0\u1eddng.<\/p>\n
Th\u1ea3i tr\u1eeb: Th\u1eddi gian b\u00e1n th\u1ea3i trong huy\u1ebft t\u01b0\u01a1ng trung b\u00ecnh l\u00e0 kho\u1ea3ng 1,3 gi\u1edd. Kho\u1ea3ng 80% l\u01b0\u1ee3ng thu\u1ed1c \u0111\u00e3 d\u00f9ng \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng ch\u1ea5t chuy\u1ec3n h\u00f3a, ph\u1ea7n c\u00f2n l\u1ea1i \u0111\u01b0\u1ee3c th\u1ea3i ra ngo\u00e0i qua ph\u00e2n. L\u01b0\u1ee3ng thu\u1ed1c c\u00f2n nguy\u00ean v\u1eb9n trong n\u01b0\u1edbc ti\u1ec3u r\u1ea5t nh\u1ecf, d\u01b0\u1edbi 1%.<\/p>\n
Thu\u1ed1c Ezdixum 40 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n\n- Vi\u00eam th\u1ef1c qu\u1ea3n do tr\u00e0o ng\u01b0\u1ee3c m\u1ee9c \u0111\u1ed9 n\u1eb7ng (c\u00f3 tr\u1ee3t x\u01b0\u1edbc ho\u1eb7c bi\u1ebfn ch\u1ee9ng n\u1ed9i soi).<\/li>\n
- Lo\u00e9t d\u1ea1 d\u00e0y \u2013 t\u00e1 tr\u00e0ng li\u00ean quan \u0111\u1ebfn vi khu\u1ea9n Helicobacter pylori (ph\u1ed1i h\u1ee3p kh\u00e1ng sinh).<\/li>\n
- H\u1ed9i ch\u1ee9ng Zollinger-Ellison ho\u1eb7c c\u00e1c t\u00ecnh tr\u1ea1ng t\u0103ng ti\u1ebft acid d\u1ea1 d\u00e0y b\u1ec7nh l\u00fd kh\u00e1c.<\/li>\n<\/ul>\n
![\"Ezdixum](\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Ezdixum-40.jpg\" "\\"\\"")
Ezdixum 40 l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd d\u1ea1 d\u00e0y nh\u01b0 vi\u00eam th\u1ef1c qu\u1ea3n tr\u00e0o ng\u01b0\u1ee3c, lo\u00e9t do vi khu\u1ea9n HP v\u00e0 h\u1ed9i ch\u1ee9ng t\u0103ng ti\u1ebft acid \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean nang<\/figcaption><\/figure>\nLi\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\nLi\u1ec1u d\u00f9ng<\/h3>\n\n- Tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y \u2013 th\u1ef1c qu\u1ea3n c\u00f3 vi\u00eam th\u1ef1c qu\u1ea3n: U\u1ed1ng 1 vi\u00ean 40mg\/ng\u00e0y, trong 4\u20138 tu\u1ea7n; c\u00f3 th\u1ec3 k\u00e9o d\u00e0i th\u00eam n\u1ebfu c\u1ea7n thi\u1ebft d\u1ef1a tr\u00ean \u0111\u00e1nh gi\u00e1 l\u00e2m s\u00e0ng.<\/li>\n
- Lo\u00e9t do H. pylori: D\u00f9ng ph\u1ed1i h\u1ee3p theo ph\u00e1c \u0111\u1ed3 3 thu\u1ed1c (th\u01b0\u1eddng c\u00f9ng amoxicillin v\u00e0 clarithromycin), d\u00f9ng li\u1ec1u t\u01b0\u01a1ng t\u1ef1 tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y-th\u1ef1c qu\u1ea3n trong 10 ng\u00e0y.<\/li>\n
- H\u1ed9i ch\u1ee9ng Zollinger-Ellison: Kh\u1edfi \u0111\u1ea7u v\u1edbi 1 vi\u00ean 40mg\/ng\u00e0y, sau \u0111\u00f3 \u0111i\u1ec1u ch\u1ec9nh t\u00f9y theo \u0111\u00e1p \u1ee9ng. N\u1ebfu t\u1ed5ng li\u1ec1u v\u01b0\u1ee3t 2 vi\u00ean\/ng\u00e0y (80mg) n\u00ean chia l\u00e0m 2 l\u1ea7n u\u1ed1ng.<\/li>\n<\/ul>\n
C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n\n- D\u00f9ng Ezdixum 40 tr\u01b0\u1edbc b\u1eefa \u0103n kho\u1ea3ng 1 gi\u1edd.<\/li>\n
- N\u00ean nu\u1ed1t nguy\u00ean vi\u00ean nang, kh\u00f4ng nhai ho\u1eb7c nghi\u1ec1n. V\u1edbi b\u1ec7nh nh\u00e2n kh\u00f3 nu\u1ed1t, c\u00f3 th\u1ec3 m\u1edf nang v\u00e0 r\u1eafc h\u1ea1t thu\u1ed1c v\u00e0o s\u1eefa chua ho\u1eb7c sinh t\u1ed1 \u0111\u1ec3 u\u1ed1ng ngay.<\/li>\n<\/ul>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Ezdixum 40 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n\n- Ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi esomeprazole, c\u00e1c thu\u1ed1c c\u00f9ng nh\u00f3m \u1ee9c ch\u1ebf b\u01a1m proton ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o trong c\u00f4ng th\u1ee9c thu\u1ed1c.<\/li>\n
- B\u1ec7nh nh\u00e2n suy gan n\u1eb7ng c\u1ea7n tr\u00e1nh s\u1eed d\u1ee5ng li\u1ec1u cao, li\u1ec1u t\u1ed1i \u0111a khuy\u1ebfn ngh\u1ecb l\u00e0 \u00bd vi\u00ean\/ng\u00e0y (~ 20mg)<\/li>\n
- Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng cho tr\u1ebb em d\u01b0\u1edbi 12 tu\u1ed5i do ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u an to\u00e0n.<\/li>\n<\/ul>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\nTh\u1eadn tr\u1ecdng<\/h3>\n\n- C\u00f3 th\u1ec3 c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u, \u0111\u1eb7c bi\u1ec7t trong suy gan n\u1eb7ng. Theo d\u00f5i ch\u1ee9c n\u0103ng gan v\u00e0 th\u1eadn n\u1ebfu d\u00f9ng k\u00e9o d\u00e0i.<\/li>\n
- C\u1ea7n th\u1eadn tr\u1ecdng v\u1edbi ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.
\nPh\u1ea3i ng\u1eebng thu\u1ed1c ngay n\u1ebfu c\u00f3 d\u1ea5u hi\u1ec7u ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng.<\/li>\n - C\u1ea7n theo d\u00f5i \u0111\u1ecbnh k\u1ef3 n\u1ebfu d\u00f9ng l\u00e2u d\u00e0i v\u00ec nguy c\u01a1 thi\u1ebfu h\u1ee5t vitamin B12, magnesi ho\u1eb7c lo\u00e3ng x\u01b0\u01a1ng<\/li>\n<\/ul>\n
T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n
Th\u01b0\u1eddng g\u1eb7p (\u22651\/100):<\/p>\n
\n- To\u00e0n th\u00e2n: \u0110au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, n\u1ed5i ban.<\/li>\n
- Ti\u00eau h\u00f3a: Bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, t\u00e1o b\u00f3n, \u0111\u1ea7y h\u01a1i, kh\u00f4 mi\u1ec7ng.<\/li>\n<\/ul>\n
\u00cdt g\u1eb7p (\u22651\/1000 \u0111\u1ebfn <1\/100):<\/p>\n
\n- To\u00e0n th\u00e2n: M\u1ec7t m\u1ecfi, m\u1ea5t ng\u1ee7, bu\u1ed3n ng\u1ee7, ng\u1ee9a, ph\u00e1t ban, r\u1ed1i lo\u1ea1n th\u1ecb l\u1ef1c.<\/li>\n<\/ul>\n
Hi\u1ebfm g\u1eb7p (<1\/1000):<\/p>\n
\n- To\u00e0n th\u00e2n: S\u1ed1t, \u0111\u1ed5 m\u1ed3 h\u00f4i, ph\u00f9 ngo\u1ea1i bi\u00ean, ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng nh\u01b0 m\u1ec1 \u0111ay, ph\u00f9 m\u1ea1ch, co th\u1eaft ph\u1ebf qu\u1ea3n, s\u1ed1c ph\u1ea3n v\u1ec7, m\u1eabn c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng.<\/li>\n
- Th\u1ea7n kinh trung \u01b0\u01a1ng: K\u00edch \u0111\u1ed9ng, tr\u1ea7m c\u1ea3m, l\u00fa l\u1eabn tho\u00e1ng qua, \u1ea3o gi\u00e1c \u1edf b\u1ec7nh nh\u00e2n n\u1eb7ng.<\/li>\n
- Huy\u1ebft h\u1ecdc: Gi\u1ea3m b\u1ea1ch c\u1ea7u, gi\u1ea3m ti\u1ec3u c\u1ea7u, m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t.<\/li>\n
- Gan: T\u0103ng men gan, vi\u00eam gan, v\u00e0ng da, suy gan.<\/li>\n
- Ti\u00eau h\u00f3a: R\u1ed1i lo\u1ea1n v\u1ecb gi\u00e1c.<\/li>\n
- C\u01a1 x\u01b0\u01a1ng kh\u1edbp: \u0110au c\u01a1, \u0111au kh\u1edbp.<\/li>\n
- Th\u1eadn: Vi\u00eam th\u1eadn k\u1ebd.<\/li>\n
- Da: Ph\u1ea3n \u1ee9ng n\u1eb7ng nh\u01b0 h\u1ed9i ch\u1ee9ng Stevens-Johnson, ban ph\u1ed3ng r\u1ed9p, ho\u1ea1i t\u1eed bi\u1ec3u b\u00ec nhi\u1ec5m \u0111\u1ed9c, vi\u00eam da.<\/li>\n<\/ul>\n
L\u01b0u \u00fd: C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton nh\u01b0 esomeprazole c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m \u0111\u1ed9 acid c\u1ee7a d\u1ecbch v\u1ecb, t\u1eeb \u0111\u00f3 l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/p>\n
T\u01b0\u01a1ng t\u00e1c<\/h3>\n\n- Esomeprazole c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 h\u1ea5p thu c\u1ee7a c\u00e1c thu\u1ed1c ph\u1ee5 thu\u1ed9c v\u00e0o \u0111\u1ed9 acid c\u1ee7a d\u1ea1 d\u00e0y nh\u01b0 ketoconazole, mu\u1ed1i s\u1eaft ho\u1eb7c digoxin.<\/li>\n
- Khi s\u1eed d\u1ee5ng ph\u1ed1i h\u1ee3p v\u1edbi clarithromycin v\u00e0 amoxicillin, n\u1ed3ng \u0111\u1ed9 esomeprazole trong m\u00e1u c\u00f3 th\u1ec3 t\u0103ng nh\u1eb9.<\/li>\n
- Thu\u1ed1c c\u00f2n l\u00e0m gi\u1ea3m \u0111\u1ed9 thanh th\u1ea3i c\u1ee7a diazepam khi d\u00f9ng chung do t\u01b0\u01a1ng t\u00e1c t\u1ea1i enzym CYP2C19.<\/li>\n<\/ul>\n
L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n
Ph\u1ee5 n\u1eef c\u00f3 thai:<\/p>\n
Hi\u1ec7n ch\u01b0a c\u00f3 \u0111\u1ee7 b\u1eb1ng ch\u1ee9ng l\u00e2m s\u00e0ng \u0111\u1ec3 kh\u1eb3ng \u0111\u1ecbnh m\u1ee9c \u0111\u1ed9 an to\u00e0n khi s\u1eed d\u1ee5ng esomeprazole trong thai k\u1ef3. Do \u0111\u00f3, thu\u1ed1c ch\u1ec9 n\u00ean \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho ph\u1ee5 n\u1eef \u0111ang mang thai trong nh\u1eefng t\u00ecnh hu\u1ed1ng th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft v\u00e0 ph\u1ea3i \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc k\u1ef9 l\u01b0\u1ee1ng.<\/p>\n
Ph\u1ee5 n\u1eef cho con b\u00fa:<\/p>\n
D\u1eef li\u1ec7u v\u1ec1 vi\u1ec7c esomeprazole c\u00f3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 c\u00f2n h\u1ea1n ch\u1ebf. Tuy nhi\u00ean, do kh\u1ea3 n\u0103ng b\u00e0i ti\u1ebft c\u1ee7a thu\u1ed1c qua s\u1eefa kh\u00f4ng th\u1ec3 lo\u1ea1i tr\u1eeb, c\u1ea7n \u0111\u01b0a ra quy\u1ebft \u0111\u1ecbnh gi\u1eefa vi\u1ec7c t\u1ea1m ng\u1eebng cho con b\u00fa ho\u1eb7c ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c, t\u00f9y theo t\u1ea7m quan tr\u1ecdng c\u1ee7a vi\u1ec7c \u0111i\u1ec1u tr\u1ecb \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi m\u1eb9.<\/p>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n
Thu\u1ed1c kh\u00f4ng \u1ea3nh h\u01b0\u1edfng tr\u1ef1c ti\u1ebfp \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe hay l\u00e0m vi\u1ec7c v\u1edbi m\u00e1y m\u00f3c. Tuy nhi\u00ean, n\u1ebfu xu\u1ea5t hi\u1ec7n c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 ch\u00f3ng m\u1eb7t, m\u1ec7t m\u1ecfi, n\u00ean tr\u00e1nh th\u1ef1c hi\u1ec7n c\u00e1c c\u00f4ng vi\u1ec7c \u0111\u00f2i h\u1ecfi s\u1ef1 t\u1ec9nh t\u00e1o cao cho \u0111\u1ebfn khi n\u1eafm \u0111\u01b0\u1ee3c t\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean th\u1ea7n kinh c\u1ee7a thu\u1ed1c \u0111\u1ed1i v\u1edbi b\u1ea3n th\u00e2n ch\u00ednh ng\u01b0\u1eddi b\u1ec7nh.<\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n
D\u1eef li\u1ec7u v\u1ec1 t\u00ecnh tr\u1ea1ng d\u00f9ng qu\u00e1 li\u1ec1u esomeprazole c\u00f2n h\u1ea1n ch\u1ebf. Tr\u01b0\u1eddng h\u1ee3p hi\u1ebfm ghi nh\u1eadn li\u1ec1u l\u00ean \u0111\u1ebfn 280mg c\u00f3 th\u1ec3 g\u00e2y ra tri\u1ec7u ch\u1ee9ng nh\u01b0 m\u1ec7t m\u1ecfi v\u00e0 r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a. C\u00e1c li\u1ec1u \u0111\u01a1n \u0111\u1ebfn 80mg v\u1eabn \u0111\u01b0\u1ee3c xem l\u00e0 an to\u00e0n.<\/p>\n
Esomeprazole li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng, n\u00ean vi\u1ec7c lo\u1ea1i b\u1ecf b\u1eb1ng l\u1ecdc m\u00e1u l\u00e0 kh\u00f4ng hi\u1ec7u qu\u1ea3. Hi\u1ec7n ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u. N\u1ebfu qu\u00e1 li\u1ec1u x\u1ea3y ra, n\u00ean \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 v\u00e0 theo d\u00f5i tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng.<\/p>\n
B\u1ea3o qu\u1ea3n<\/h3>\n\n- Gi\u1eef Ezdixum 40 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (<30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/li>\n
- Kh\u00f4ng \u0111\u1ec3 Ezdixum 40 trong t\u1ea7m v\u1edbi tr\u1ebb em<\/li>\n
- Kh\u00f4ng s\u1eed d\u1ee5ng Ezdixum 40 khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/li>\n<\/ul>\n
Thu\u1ed1c Ezdixum 40 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n
Ezdixum 40 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Ezdixum 40 c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n
Tr\u01b0\u1eddng h\u1ee3p Ezdixum 40 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Ezdixum 40 nh\u01b0:<\/p>\n
Esomeprazol 20 \u2013 US<\/a> c\u00f3 th\u00e0nh ph\u1ea7n l\u00e0 Esomeprazol v\u1edbi h\u00e0m l\u01b0\u1ee3ng l\u00e0 20mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH US Pharma USA, gi\u00fap \u0111i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng lo\u00e9t d\u1ea1 d\u00e0y – t\u00e1 tr\u00e0ng.<\/p>\n
Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\nLi\u1ec1u d\u00f9ng<\/h3>\n\n- Tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y \u2013 th\u1ef1c qu\u1ea3n c\u00f3 vi\u00eam th\u1ef1c qu\u1ea3n: U\u1ed1ng 1 vi\u00ean 40mg\/ng\u00e0y, trong 4\u20138 tu\u1ea7n; c\u00f3 th\u1ec3 k\u00e9o d\u00e0i th\u00eam n\u1ebfu c\u1ea7n thi\u1ebft d\u1ef1a tr\u00ean \u0111\u00e1nh gi\u00e1 l\u00e2m s\u00e0ng.<\/li>\n
- Lo\u00e9t do H. pylori: D\u00f9ng ph\u1ed1i h\u1ee3p theo ph\u00e1c \u0111\u1ed3 3 thu\u1ed1c (th\u01b0\u1eddng c\u00f9ng amoxicillin v\u00e0 clarithromycin), d\u00f9ng li\u1ec1u t\u01b0\u01a1ng t\u1ef1 tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y-th\u1ef1c qu\u1ea3n trong 10 ng\u00e0y.<\/li>\n
- H\u1ed9i ch\u1ee9ng Zollinger-Ellison: Kh\u1edfi \u0111\u1ea7u v\u1edbi 1 vi\u00ean 40mg\/ng\u00e0y, sau \u0111\u00f3 \u0111i\u1ec1u ch\u1ec9nh t\u00f9y theo \u0111\u00e1p \u1ee9ng. N\u1ebfu t\u1ed5ng li\u1ec1u v\u01b0\u1ee3t 2 vi\u00ean\/ng\u00e0y (80mg) n\u00ean chia l\u00e0m 2 l\u1ea7n u\u1ed1ng.<\/li>\n<\/ul>\n
C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n\n- D\u00f9ng Ezdixum 40 tr\u01b0\u1edbc b\u1eefa \u0103n kho\u1ea3ng 1 gi\u1edd.<\/li>\n
- N\u00ean nu\u1ed1t nguy\u00ean vi\u00ean nang, kh\u00f4ng nhai ho\u1eb7c nghi\u1ec1n. V\u1edbi b\u1ec7nh nh\u00e2n kh\u00f3 nu\u1ed1t, c\u00f3 th\u1ec3 m\u1edf nang v\u00e0 r\u1eafc h\u1ea1t thu\u1ed1c v\u00e0o s\u1eefa chua ho\u1eb7c sinh t\u1ed1 \u0111\u1ec3 u\u1ed1ng ngay.<\/li>\n<\/ul>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Ezdixum 40 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n\n- Ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi esomeprazole, c\u00e1c thu\u1ed1c c\u00f9ng nh\u00f3m \u1ee9c ch\u1ebf b\u01a1m proton ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o trong c\u00f4ng th\u1ee9c thu\u1ed1c.<\/li>\n
- B\u1ec7nh nh\u00e2n suy gan n\u1eb7ng c\u1ea7n tr\u00e1nh s\u1eed d\u1ee5ng li\u1ec1u cao, li\u1ec1u t\u1ed1i \u0111a khuy\u1ebfn ngh\u1ecb l\u00e0 \u00bd vi\u00ean\/ng\u00e0y (~ 20mg)<\/li>\n
- Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng cho tr\u1ebb em d\u01b0\u1edbi 12 tu\u1ed5i do ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u an to\u00e0n.<\/li>\n<\/ul>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\nTh\u1eadn tr\u1ecdng<\/h3>\n\n- C\u00f3 th\u1ec3 c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u, \u0111\u1eb7c bi\u1ec7t trong suy gan n\u1eb7ng. Theo d\u00f5i ch\u1ee9c n\u0103ng gan v\u00e0 th\u1eadn n\u1ebfu d\u00f9ng k\u00e9o d\u00e0i.<\/li>\n
- C\u1ea7n th\u1eadn tr\u1ecdng v\u1edbi ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.
\nPh\u1ea3i ng\u1eebng thu\u1ed1c ngay n\u1ebfu c\u00f3 d\u1ea5u hi\u1ec7u ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng.<\/li>\n - C\u1ea7n theo d\u00f5i \u0111\u1ecbnh k\u1ef3 n\u1ebfu d\u00f9ng l\u00e2u d\u00e0i v\u00ec nguy c\u01a1 thi\u1ebfu h\u1ee5t vitamin B12, magnesi ho\u1eb7c lo\u00e3ng x\u01b0\u01a1ng<\/li>\n<\/ul>\n
T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n
Th\u01b0\u1eddng g\u1eb7p (\u22651\/100):<\/p>\n
\n- To\u00e0n th\u00e2n: \u0110au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, n\u1ed5i ban.<\/li>\n
- Ti\u00eau h\u00f3a: Bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, t\u00e1o b\u00f3n, \u0111\u1ea7y h\u01a1i, kh\u00f4 mi\u1ec7ng.<\/li>\n<\/ul>\n
\u00cdt g\u1eb7p (\u22651\/1000 \u0111\u1ebfn <1\/100):<\/p>\n
\n- To\u00e0n th\u00e2n: M\u1ec7t m\u1ecfi, m\u1ea5t ng\u1ee7, bu\u1ed3n ng\u1ee7, ng\u1ee9a, ph\u00e1t ban, r\u1ed1i lo\u1ea1n th\u1ecb l\u1ef1c.<\/li>\n<\/ul>\n
Hi\u1ebfm g\u1eb7p (<1\/1000):<\/p>\n
\n- To\u00e0n th\u00e2n: S\u1ed1t, \u0111\u1ed5 m\u1ed3 h\u00f4i, ph\u00f9 ngo\u1ea1i bi\u00ean, ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng nh\u01b0 m\u1ec1 \u0111ay, ph\u00f9 m\u1ea1ch, co th\u1eaft ph\u1ebf qu\u1ea3n, s\u1ed1c ph\u1ea3n v\u1ec7, m\u1eabn c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng.<\/li>\n
- Th\u1ea7n kinh trung \u01b0\u01a1ng: K\u00edch \u0111\u1ed9ng, tr\u1ea7m c\u1ea3m, l\u00fa l\u1eabn tho\u00e1ng qua, \u1ea3o gi\u00e1c \u1edf b\u1ec7nh nh\u00e2n n\u1eb7ng.<\/li>\n
- Huy\u1ebft h\u1ecdc: Gi\u1ea3m b\u1ea1ch c\u1ea7u, gi\u1ea3m ti\u1ec3u c\u1ea7u, m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t.<\/li>\n
- Gan: T\u0103ng men gan, vi\u00eam gan, v\u00e0ng da, suy gan.<\/li>\n
- Ti\u00eau h\u00f3a: R\u1ed1i lo\u1ea1n v\u1ecb gi\u00e1c.<\/li>\n
- C\u01a1 x\u01b0\u01a1ng kh\u1edbp: \u0110au c\u01a1, \u0111au kh\u1edbp.<\/li>\n
- Th\u1eadn: Vi\u00eam th\u1eadn k\u1ebd.<\/li>\n
- Da: Ph\u1ea3n \u1ee9ng n\u1eb7ng nh\u01b0 h\u1ed9i ch\u1ee9ng Stevens-Johnson, ban ph\u1ed3ng r\u1ed9p, ho\u1ea1i t\u1eed bi\u1ec3u b\u00ec nhi\u1ec5m \u0111\u1ed9c, vi\u00eam da.<\/li>\n<\/ul>\n
L\u01b0u \u00fd: C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton nh\u01b0 esomeprazole c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m \u0111\u1ed9 acid c\u1ee7a d\u1ecbch v\u1ecb, t\u1eeb \u0111\u00f3 l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/p>\n
T\u01b0\u01a1ng t\u00e1c<\/h3>\n\n- Esomeprazole c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 h\u1ea5p thu c\u1ee7a c\u00e1c thu\u1ed1c ph\u1ee5 thu\u1ed9c v\u00e0o \u0111\u1ed9 acid c\u1ee7a d\u1ea1 d\u00e0y nh\u01b0 ketoconazole, mu\u1ed1i s\u1eaft ho\u1eb7c digoxin.<\/li>\n
- Khi s\u1eed d\u1ee5ng ph\u1ed1i h\u1ee3p v\u1edbi clarithromycin v\u00e0 amoxicillin, n\u1ed3ng \u0111\u1ed9 esomeprazole trong m\u00e1u c\u00f3 th\u1ec3 t\u0103ng nh\u1eb9.<\/li>\n
- Thu\u1ed1c c\u00f2n l\u00e0m gi\u1ea3m \u0111\u1ed9 thanh th\u1ea3i c\u1ee7a diazepam khi d\u00f9ng chung do t\u01b0\u01a1ng t\u00e1c t\u1ea1i enzym CYP2C19.<\/li>\n<\/ul>\n
L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n
Ph\u1ee5 n\u1eef c\u00f3 thai:<\/p>\n
Hi\u1ec7n ch\u01b0a c\u00f3 \u0111\u1ee7 b\u1eb1ng ch\u1ee9ng l\u00e2m s\u00e0ng \u0111\u1ec3 kh\u1eb3ng \u0111\u1ecbnh m\u1ee9c \u0111\u1ed9 an to\u00e0n khi s\u1eed d\u1ee5ng esomeprazole trong thai k\u1ef3. Do \u0111\u00f3, thu\u1ed1c ch\u1ec9 n\u00ean \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho ph\u1ee5 n\u1eef \u0111ang mang thai trong nh\u1eefng t\u00ecnh hu\u1ed1ng th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft v\u00e0 ph\u1ea3i \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc k\u1ef9 l\u01b0\u1ee1ng.<\/p>\n
Ph\u1ee5 n\u1eef cho con b\u00fa:<\/p>\n
D\u1eef li\u1ec7u v\u1ec1 vi\u1ec7c esomeprazole c\u00f3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 c\u00f2n h\u1ea1n ch\u1ebf. Tuy nhi\u00ean, do kh\u1ea3 n\u0103ng b\u00e0i ti\u1ebft c\u1ee7a thu\u1ed1c qua s\u1eefa kh\u00f4ng th\u1ec3 lo\u1ea1i tr\u1eeb, c\u1ea7n \u0111\u01b0a ra quy\u1ebft \u0111\u1ecbnh gi\u1eefa vi\u1ec7c t\u1ea1m ng\u1eebng cho con b\u00fa ho\u1eb7c ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c, t\u00f9y theo t\u1ea7m quan tr\u1ecdng c\u1ee7a vi\u1ec7c \u0111i\u1ec1u tr\u1ecb \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi m\u1eb9.<\/p>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n
Thu\u1ed1c kh\u00f4ng \u1ea3nh h\u01b0\u1edfng tr\u1ef1c ti\u1ebfp \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe hay l\u00e0m vi\u1ec7c v\u1edbi m\u00e1y m\u00f3c. Tuy nhi\u00ean, n\u1ebfu xu\u1ea5t hi\u1ec7n c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 ch\u00f3ng m\u1eb7t, m\u1ec7t m\u1ecfi, n\u00ean tr\u00e1nh th\u1ef1c hi\u1ec7n c\u00e1c c\u00f4ng vi\u1ec7c \u0111\u00f2i h\u1ecfi s\u1ef1 t\u1ec9nh t\u00e1o cao cho \u0111\u1ebfn khi n\u1eafm \u0111\u01b0\u1ee3c t\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean th\u1ea7n kinh c\u1ee7a thu\u1ed1c \u0111\u1ed1i v\u1edbi b\u1ea3n th\u00e2n ch\u00ednh ng\u01b0\u1eddi b\u1ec7nh.<\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n
D\u1eef li\u1ec7u v\u1ec1 t\u00ecnh tr\u1ea1ng d\u00f9ng qu\u00e1 li\u1ec1u esomeprazole c\u00f2n h\u1ea1n ch\u1ebf. Tr\u01b0\u1eddng h\u1ee3p hi\u1ebfm ghi nh\u1eadn li\u1ec1u l\u00ean \u0111\u1ebfn 280mg c\u00f3 th\u1ec3 g\u00e2y ra tri\u1ec7u ch\u1ee9ng nh\u01b0 m\u1ec7t m\u1ecfi v\u00e0 r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a. C\u00e1c li\u1ec1u \u0111\u01a1n \u0111\u1ebfn 80mg v\u1eabn \u0111\u01b0\u1ee3c xem l\u00e0 an to\u00e0n.<\/p>\n
Esomeprazole li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng, n\u00ean vi\u1ec7c lo\u1ea1i b\u1ecf b\u1eb1ng l\u1ecdc m\u00e1u l\u00e0 kh\u00f4ng hi\u1ec7u qu\u1ea3. Hi\u1ec7n ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u. N\u1ebfu qu\u00e1 li\u1ec1u x\u1ea3y ra, n\u00ean \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 v\u00e0 theo d\u00f5i tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng.<\/p>\n
B\u1ea3o qu\u1ea3n<\/h3>\n\n- Gi\u1eef Ezdixum 40 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (<30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/li>\n
- Kh\u00f4ng \u0111\u1ec3 Ezdixum 40 trong t\u1ea7m v\u1edbi tr\u1ebb em<\/li>\n
- Kh\u00f4ng s\u1eed d\u1ee5ng Ezdixum 40 khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/li>\n<\/ul>\n
Thu\u1ed1c Ezdixum 40 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n
Ezdixum 40 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Ezdixum 40 c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n
Tr\u01b0\u1eddng h\u1ee3p Ezdixum 40 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Ezdixum 40 nh\u01b0:<\/p>\n
Esomeprazol 20 \u2013 US<\/a> c\u00f3 th\u00e0nh ph\u1ea7n l\u00e0 Esomeprazol v\u1edbi h\u00e0m l\u01b0\u1ee3ng l\u00e0 20mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH US Pharma USA, gi\u00fap \u0111i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng lo\u00e9t d\u1ea1 d\u00e0y – t\u00e1 tr\u00e0ng.<\/p>\n
- \n
- Tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y \u2013 th\u1ef1c qu\u1ea3n c\u00f3 vi\u00eam th\u1ef1c qu\u1ea3n: U\u1ed1ng 1 vi\u00ean 40mg\/ng\u00e0y, trong 4\u20138 tu\u1ea7n; c\u00f3 th\u1ec3 k\u00e9o d\u00e0i th\u00eam n\u1ebfu c\u1ea7n thi\u1ebft d\u1ef1a tr\u00ean \u0111\u00e1nh gi\u00e1 l\u00e2m s\u00e0ng.<\/li>\n
- Lo\u00e9t do H. pylori: D\u00f9ng ph\u1ed1i h\u1ee3p theo ph\u00e1c \u0111\u1ed3 3 thu\u1ed1c (th\u01b0\u1eddng c\u00f9ng amoxicillin v\u00e0 clarithromycin), d\u00f9ng li\u1ec1u t\u01b0\u01a1ng t\u1ef1 tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y-th\u1ef1c qu\u1ea3n trong 10 ng\u00e0y.<\/li>\n
- H\u1ed9i ch\u1ee9ng Zollinger-Ellison: Kh\u1edfi \u0111\u1ea7u v\u1edbi 1 vi\u00ean 40mg\/ng\u00e0y, sau \u0111\u00f3 \u0111i\u1ec1u ch\u1ec9nh t\u00f9y theo \u0111\u00e1p \u1ee9ng. N\u1ebfu t\u1ed5ng li\u1ec1u v\u01b0\u1ee3t 2 vi\u00ean\/ng\u00e0y (80mg) n\u00ean chia l\u00e0m 2 l\u1ea7n u\u1ed1ng.<\/li>\n<\/ul>\n
C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n
- \n
- D\u00f9ng Ezdixum 40 tr\u01b0\u1edbc b\u1eefa \u0103n kho\u1ea3ng 1 gi\u1edd.<\/li>\n
- N\u00ean nu\u1ed1t nguy\u00ean vi\u00ean nang, kh\u00f4ng nhai ho\u1eb7c nghi\u1ec1n. V\u1edbi b\u1ec7nh nh\u00e2n kh\u00f3 nu\u1ed1t, c\u00f3 th\u1ec3 m\u1edf nang v\u00e0 r\u1eafc h\u1ea1t thu\u1ed1c v\u00e0o s\u1eefa chua ho\u1eb7c sinh t\u1ed1 \u0111\u1ec3 u\u1ed1ng ngay.<\/li>\n<\/ul>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Ezdixum 40 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n
- \n
- Ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi esomeprazole, c\u00e1c thu\u1ed1c c\u00f9ng nh\u00f3m \u1ee9c ch\u1ebf b\u01a1m proton ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o trong c\u00f4ng th\u1ee9c thu\u1ed1c.<\/li>\n
- B\u1ec7nh nh\u00e2n suy gan n\u1eb7ng c\u1ea7n tr\u00e1nh s\u1eed d\u1ee5ng li\u1ec1u cao, li\u1ec1u t\u1ed1i \u0111a khuy\u1ebfn ngh\u1ecb l\u00e0 \u00bd vi\u00ean\/ng\u00e0y (~ 20mg)<\/li>\n
- Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng cho tr\u1ebb em d\u01b0\u1edbi 12 tu\u1ed5i do ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u an to\u00e0n.<\/li>\n<\/ul>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n
Th\u1eadn tr\u1ecdng<\/h3>\n
- \n
- C\u00f3 th\u1ec3 c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u, \u0111\u1eb7c bi\u1ec7t trong suy gan n\u1eb7ng. Theo d\u00f5i ch\u1ee9c n\u0103ng gan v\u00e0 th\u1eadn n\u1ebfu d\u00f9ng k\u00e9o d\u00e0i.<\/li>\n
- C\u1ea7n th\u1eadn tr\u1ecdng v\u1edbi ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.
\nPh\u1ea3i ng\u1eebng thu\u1ed1c ngay n\u1ebfu c\u00f3 d\u1ea5u hi\u1ec7u ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng.<\/li>\n - C\u1ea7n theo d\u00f5i \u0111\u1ecbnh k\u1ef3 n\u1ebfu d\u00f9ng l\u00e2u d\u00e0i v\u00ec nguy c\u01a1 thi\u1ebfu h\u1ee5t vitamin B12, magnesi ho\u1eb7c lo\u00e3ng x\u01b0\u01a1ng<\/li>\n<\/ul>\n
T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n
Th\u01b0\u1eddng g\u1eb7p (\u22651\/100):<\/p>\n
- \n
- To\u00e0n th\u00e2n: \u0110au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, n\u1ed5i ban.<\/li>\n
- Ti\u00eau h\u00f3a: Bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, t\u00e1o b\u00f3n, \u0111\u1ea7y h\u01a1i, kh\u00f4 mi\u1ec7ng.<\/li>\n<\/ul>\n
\u00cdt g\u1eb7p (\u22651\/1000 \u0111\u1ebfn <1\/100):<\/p>\n
- \n
- To\u00e0n th\u00e2n: M\u1ec7t m\u1ecfi, m\u1ea5t ng\u1ee7, bu\u1ed3n ng\u1ee7, ng\u1ee9a, ph\u00e1t ban, r\u1ed1i lo\u1ea1n th\u1ecb l\u1ef1c.<\/li>\n<\/ul>\n
Hi\u1ebfm g\u1eb7p (<1\/1000):<\/p>\n
- \n
- To\u00e0n th\u00e2n: S\u1ed1t, \u0111\u1ed5 m\u1ed3 h\u00f4i, ph\u00f9 ngo\u1ea1i bi\u00ean, ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng nh\u01b0 m\u1ec1 \u0111ay, ph\u00f9 m\u1ea1ch, co th\u1eaft ph\u1ebf qu\u1ea3n, s\u1ed1c ph\u1ea3n v\u1ec7, m\u1eabn c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng.<\/li>\n
- Th\u1ea7n kinh trung \u01b0\u01a1ng: K\u00edch \u0111\u1ed9ng, tr\u1ea7m c\u1ea3m, l\u00fa l\u1eabn tho\u00e1ng qua, \u1ea3o gi\u00e1c \u1edf b\u1ec7nh nh\u00e2n n\u1eb7ng.<\/li>\n
- Huy\u1ebft h\u1ecdc: Gi\u1ea3m b\u1ea1ch c\u1ea7u, gi\u1ea3m ti\u1ec3u c\u1ea7u, m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t.<\/li>\n
- Gan: T\u0103ng men gan, vi\u00eam gan, v\u00e0ng da, suy gan.<\/li>\n
- Ti\u00eau h\u00f3a: R\u1ed1i lo\u1ea1n v\u1ecb gi\u00e1c.<\/li>\n
- C\u01a1 x\u01b0\u01a1ng kh\u1edbp: \u0110au c\u01a1, \u0111au kh\u1edbp.<\/li>\n
- Th\u1eadn: Vi\u00eam th\u1eadn k\u1ebd.<\/li>\n
- Da: Ph\u1ea3n \u1ee9ng n\u1eb7ng nh\u01b0 h\u1ed9i ch\u1ee9ng Stevens-Johnson, ban ph\u1ed3ng r\u1ed9p, ho\u1ea1i t\u1eed bi\u1ec3u b\u00ec nhi\u1ec5m \u0111\u1ed9c, vi\u00eam da.<\/li>\n<\/ul>\n
L\u01b0u \u00fd: C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton nh\u01b0 esomeprazole c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m \u0111\u1ed9 acid c\u1ee7a d\u1ecbch v\u1ecb, t\u1eeb \u0111\u00f3 l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/p>\n
T\u01b0\u01a1ng t\u00e1c<\/h3>\n
- \n
- Esomeprazole c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 h\u1ea5p thu c\u1ee7a c\u00e1c thu\u1ed1c ph\u1ee5 thu\u1ed9c v\u00e0o \u0111\u1ed9 acid c\u1ee7a d\u1ea1 d\u00e0y nh\u01b0 ketoconazole, mu\u1ed1i s\u1eaft ho\u1eb7c digoxin.<\/li>\n
- Khi s\u1eed d\u1ee5ng ph\u1ed1i h\u1ee3p v\u1edbi clarithromycin v\u00e0 amoxicillin, n\u1ed3ng \u0111\u1ed9 esomeprazole trong m\u00e1u c\u00f3 th\u1ec3 t\u0103ng nh\u1eb9.<\/li>\n
- Thu\u1ed1c c\u00f2n l\u00e0m gi\u1ea3m \u0111\u1ed9 thanh th\u1ea3i c\u1ee7a diazepam khi d\u00f9ng chung do t\u01b0\u01a1ng t\u00e1c t\u1ea1i enzym CYP2C19.<\/li>\n<\/ul>\n
L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n
Ph\u1ee5 n\u1eef c\u00f3 thai:<\/p>\n
Hi\u1ec7n ch\u01b0a c\u00f3 \u0111\u1ee7 b\u1eb1ng ch\u1ee9ng l\u00e2m s\u00e0ng \u0111\u1ec3 kh\u1eb3ng \u0111\u1ecbnh m\u1ee9c \u0111\u1ed9 an to\u00e0n khi s\u1eed d\u1ee5ng esomeprazole trong thai k\u1ef3. Do \u0111\u00f3, thu\u1ed1c ch\u1ec9 n\u00ean \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho ph\u1ee5 n\u1eef \u0111ang mang thai trong nh\u1eefng t\u00ecnh hu\u1ed1ng th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft v\u00e0 ph\u1ea3i \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc k\u1ef9 l\u01b0\u1ee1ng.<\/p>\n
Ph\u1ee5 n\u1eef cho con b\u00fa:<\/p>\n
D\u1eef li\u1ec7u v\u1ec1 vi\u1ec7c esomeprazole c\u00f3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 c\u00f2n h\u1ea1n ch\u1ebf. Tuy nhi\u00ean, do kh\u1ea3 n\u0103ng b\u00e0i ti\u1ebft c\u1ee7a thu\u1ed1c qua s\u1eefa kh\u00f4ng th\u1ec3 lo\u1ea1i tr\u1eeb, c\u1ea7n \u0111\u01b0a ra quy\u1ebft \u0111\u1ecbnh gi\u1eefa vi\u1ec7c t\u1ea1m ng\u1eebng cho con b\u00fa ho\u1eb7c ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c, t\u00f9y theo t\u1ea7m quan tr\u1ecdng c\u1ee7a vi\u1ec7c \u0111i\u1ec1u tr\u1ecb \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi m\u1eb9.<\/p>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n
Thu\u1ed1c kh\u00f4ng \u1ea3nh h\u01b0\u1edfng tr\u1ef1c ti\u1ebfp \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe hay l\u00e0m vi\u1ec7c v\u1edbi m\u00e1y m\u00f3c. Tuy nhi\u00ean, n\u1ebfu xu\u1ea5t hi\u1ec7n c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 ch\u00f3ng m\u1eb7t, m\u1ec7t m\u1ecfi, n\u00ean tr\u00e1nh th\u1ef1c hi\u1ec7n c\u00e1c c\u00f4ng vi\u1ec7c \u0111\u00f2i h\u1ecfi s\u1ef1 t\u1ec9nh t\u00e1o cao cho \u0111\u1ebfn khi n\u1eafm \u0111\u01b0\u1ee3c t\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean th\u1ea7n kinh c\u1ee7a thu\u1ed1c \u0111\u1ed1i v\u1edbi b\u1ea3n th\u00e2n ch\u00ednh ng\u01b0\u1eddi b\u1ec7nh.<\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n
D\u1eef li\u1ec7u v\u1ec1 t\u00ecnh tr\u1ea1ng d\u00f9ng qu\u00e1 li\u1ec1u esomeprazole c\u00f2n h\u1ea1n ch\u1ebf. Tr\u01b0\u1eddng h\u1ee3p hi\u1ebfm ghi nh\u1eadn li\u1ec1u l\u00ean \u0111\u1ebfn 280mg c\u00f3 th\u1ec3 g\u00e2y ra tri\u1ec7u ch\u1ee9ng nh\u01b0 m\u1ec7t m\u1ecfi v\u00e0 r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a. C\u00e1c li\u1ec1u \u0111\u01a1n \u0111\u1ebfn 80mg v\u1eabn \u0111\u01b0\u1ee3c xem l\u00e0 an to\u00e0n.<\/p>\n
Esomeprazole li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng, n\u00ean vi\u1ec7c lo\u1ea1i b\u1ecf b\u1eb1ng l\u1ecdc m\u00e1u l\u00e0 kh\u00f4ng hi\u1ec7u qu\u1ea3. Hi\u1ec7n ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u. N\u1ebfu qu\u00e1 li\u1ec1u x\u1ea3y ra, n\u00ean \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 v\u00e0 theo d\u00f5i tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng.<\/p>\n
B\u1ea3o qu\u1ea3n<\/h3>\n
- \n
- Gi\u1eef Ezdixum 40 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (<30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/li>\n
- Kh\u00f4ng \u0111\u1ec3 Ezdixum 40 trong t\u1ea7m v\u1edbi tr\u1ebb em<\/li>\n
- Kh\u00f4ng s\u1eed d\u1ee5ng Ezdixum 40 khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/li>\n<\/ul>\n
Thu\u1ed1c Ezdixum 40 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n
Ezdixum 40 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Ezdixum 40 c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n
Tr\u01b0\u1eddng h\u1ee3p Ezdixum 40 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Ezdixum 40 nh\u01b0:<\/p>\n
Esomeprazol 20 \u2013 US<\/a> c\u00f3 th\u00e0nh ph\u1ea7n l\u00e0 Esomeprazol v\u1edbi h\u00e0m l\u01b0\u1ee3ng l\u00e0 20mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH US Pharma USA, gi\u00fap \u0111i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng lo\u00e9t d\u1ea1 d\u00e0y – t\u00e1 tr\u00e0ng.<\/p>\n
- To\u00e0n th\u00e2n: M\u1ec7t m\u1ecfi, m\u1ea5t ng\u1ee7, bu\u1ed3n ng\u1ee7, ng\u1ee9a, ph\u00e1t ban, r\u1ed1i lo\u1ea1n th\u1ecb l\u1ef1c.<\/li>\n<\/ul>\n