{"id":117907,"date":"2025-05-06T14:33:01","date_gmt":"2025-05-06T07:33:01","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=117907"},"modified":"2025-07-24T13:16:28","modified_gmt":"2025-07-24T06:16:28","slug":"tiepanem-neropenem-1g","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/tiepanem-neropenem-1g\/","title":{"rendered":"Tiepanem Meropenem 1g"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Tiepanem Meropenem 1g \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi ACS DOBFAR S.P.A., c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-18440-14.<\/strong><\/p>\n<h2>Tiepanem Meropenem 1g l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i l\u1ecd b\u1ed9t pha ti\u00eam truy\u1ec1n <strong>Tiepanem Meropenem 1g<\/strong> ch\u1ee9a th\u00e0nh ph\u1ea7n ch\u00ednh:<\/p>\n<ul>\n<li><strong>Meropenem<\/strong> (d\u01b0\u1edbi d\u1ea1ng Meropenem trihydrat): 1g<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: v\u1eeba \u0111\u1ee7<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-18440-14<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 l\u1ecd<\/p>\n<p>Xu\u1ea5t x\u1ee9: Italy<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Tiepanem Meropenem 1g<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<ul>\n<li>Meropenem l\u00e0 m\u1ed9t kh\u00e1ng sinh t\u1ed5ng h\u1ee3p thu\u1ed9c nh\u00f3m carbapenem. C\u01a1 ch\u1ebf di\u1ec7t khu\u1ea9n c\u1ee7a thu\u1ed1c d\u1ef1a tr\u00ean kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p v\u00e1ch t\u1ebf b\u00e0o vi khu\u1ea9n. Meropenem g\u1eafn k\u1ebft v\u00e0 l\u00e0m b\u1ea5t ho\u1ea1t c\u00e1c protein li\u00ean k\u1ebft penicillin (PBPs), \u0111\u1eb7c bi\u1ec7t l\u00e0 PBP 2, 3 v\u00e0 4 \u1edf vi khu\u1ea9n E. coli v\u00e0 P. aeruginosa. Thu\u1ed1c c\u00f3 ph\u1ed5 kh\u00e1ng khu\u1ea9n r\u1ed9ng, bao g\u1ed3m vi khu\u1ea9n Gram \u00e2m, Gram d\u01b0\u01a1ng v\u00e0 m\u1ed9t s\u1ed1 vi khu\u1ea9n k\u1ef5 kh\u00ed. Meropenem c\u00f3 kh\u1ea3 n\u0103ng b\u1ec1n v\u1eefng v\u1edbi nhi\u1ec1u lo\u1ea1i enzym beta-lactamase, tuy nhi\u00ean kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng v\u1edbi metallo-beta lactamase.<\/li>\n<li>So v\u1edbi imipenem, meropenem cho th\u1ea5y hi\u1ec7u qu\u1ea3 cao h\u01a1n \u0111\u1ed1i v\u1edbi c\u00e1c vi khu\u1ea9n thu\u1ed9c h\u1ecd Enterobacteriaceae, nh\u01b0ng l\u1ea1i c\u00f3 ho\u1ea1t t\u00ednh k\u00e9m h\u01a1n tr\u00ean vi khu\u1ea9n Gram d\u01b0\u01a1ng. Thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng tr\u00ean nhi\u1ec1u ch\u1ee7ng vi khu\u1ea9n nh\u01b0 Streptococcus pneumoniae, Staphylococcus aureus, E. coli, Pseudomonas aeruginosa v\u00e0 m\u1ed9t s\u1ed1 vi khu\u1ea9n k\u1ef5 kh\u00ed. T\u00ecnh tr\u1ea1ng kh\u00e1ng thu\u1ed1c c\u00f3 th\u1ec3 ph\u00e1t tri\u1ec3n do c\u01a1 ch\u1ebf gi\u1ea3m kh\u1ea3 n\u0103ng th\u1ea5m c\u1ee7a m\u00e0ng t\u1ebf b\u00e0o vi khu\u1ea9n ho\u1eb7c do vi khu\u1ea9n s\u1ea3n xu\u1ea5t enzym beta-lactamase. Tuy nhi\u00ean, kh\u00f4ng ghi nh\u1eadn hi\u1ec7n t\u01b0\u1ee3ng kh\u00e1ng ch\u00e9o gi\u1eefa meropenem v\u1edbi c\u00e1c nh\u00f3m kh\u00e1ng sinh quinolon, aminoglycosid, macrolid v\u00e0 tetracyclin.<\/li>\n<\/ul>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu: Meropenem \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng b\u1eb1ng \u0111\u01b0\u1eddng ti\u00eam t\u0129nh m\u1ea1ch v\u00e0 kh\u00f4ng h\u1ea5p thu qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Sau khi ti\u00eam, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh c\u1ee7a thu\u1ed1c trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c r\u1ea5t nhanh ch\u00f3ng, th\u01b0\u1eddng trong v\u00f2ng v\u00e0i ph\u00fat. Khi truy\u1ec1n t\u0129nh m\u1ea1ch, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh \u0111\u1ea1t \u0111\u01b0\u1ee3c s\u1ebd th\u1ea5p h\u01a1n so v\u1edbi ti\u00eam tr\u1ef1c ti\u1ebfp.<\/li>\n<li>Ph\u00e2n b\u1ed1: Meropenem c\u00f3 kh\u1ea3 n\u0103ng ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i trong c\u00e1c m\u00f4 v\u00e0 d\u1ecbch c\u1ee7a c\u01a1 th\u1ec3, bao g\u1ed3m c\u1ea3 d\u1ecbch n\u00e3o t\u1ee7y v\u00e0 m\u1eadt. Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 \u1edf ng\u01b0\u1eddi l\u1edbn dao \u0111\u1ed9ng t\u1eeb 15 \u0111\u1ebfn 20 l\u00edt, trong khi \u1edf tr\u1ebb em l\u00e0 kho\u1ea3ng 0,3 \u0111\u1ebfn 0,4 l\u00edt\/kg. T\u1ef7 l\u1ec7 li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng c\u1ee7a meropenem th\u1ea5p, ch\u1ec9 kho\u1ea3ng 2%, \u0111i\u1ec1u n\u00e0y cho ph\u00e9p m\u1ed9t l\u01b0\u1ee3ng l\u1edbn thu\u1ed1c duy tr\u00ec ho\u1ea1t t\u00ednh trong c\u01a1 th\u1ec3.<\/li>\n<li>Chuy\u1ec3n h\u00f3a: Meropenem \u00edt b\u1ecb chuy\u1ec3n h\u00f3a trong c\u01a1 th\u1ec3. Ph\u1ea7n l\u1edbn thu\u1ed1c t\u1ed3n t\u1ea1i \u1edf d\u1ea1ng kh\u00f4ng \u0111\u1ed5i v\u00e0 \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb m\u00e0 kh\u00f4ng tr\u1ea3i qua qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a \u0111\u00e1ng k\u1ec3 th\u00e0nh c\u00e1c ch\u1ea5t kh\u00e1c.<\/li>\n<li>Th\u1ea3i tr\u1eeb: Con \u0111\u01b0\u1eddng th\u1ea3i tr\u1eeb ch\u00ednh c\u1ee7a meropenem l\u00e0 qua th\u1eadn. Kho\u1ea3ng 70% li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i qua n\u01b0\u1edbc ti\u1ec3u trong v\u00f2ng 12 gi\u1edd. M\u1ed9t l\u01b0\u1ee3ng nh\u1ecf, kho\u1ea3ng 2% li\u1ec1u d\u00f9ng, \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua ph\u00e2n. Meropenem c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf kh\u1ecfi c\u01a1 th\u1ec3 b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p th\u1ea9m t\u00e1ch m\u00e1u. Th\u1eddi gian b\u00e1n th\u1ea3i trong huy\u1ebft thanh c\u1ee7a thu\u1ed1c kho\u1ea3ng 1 gi\u1edd v\u00e0 c\u00f3 th\u1ec3 k\u00e9o d\u00e0i \u1edf b\u1ec7nh nh\u00e2n suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Tiepanem Meropenem 1g \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<figure id=\"attachment_117908\" aria-describedby=\"caption-attachment-117908\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-117908\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Tiepanem-Meropenem-1g.jpg\" alt=\"Tiepanem Meropenem 1g \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Tiepanem-Meropenem-1g.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Tiepanem-Meropenem-1g-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Tiepanem-Meropenem-1g-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Tiepanem-Meropenem-1g-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-117908\" class=\"wp-caption-text\">Tiepanem Meropenem 1g \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n nh\u1ea1y c\u1ea3m<\/figcaption><\/figure>\n<p>Tiepanem 1g \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh nhi\u1ec5m khu\u1ea9n g\u00e2y ra b\u1edfi c\u00e1c vi khu\u1ea9n Gram \u00e2m v\u00e0 Gram d\u01b0\u01a1ng nh\u1ea1y c\u1ea3m v\u1edbi meropenem \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 3 th\u00e1ng tu\u1ed5i tr\u1edf l\u00ean. C\u1ee5 th\u1ec3, thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n<ul>\n<li>Vi\u00eam ph\u1ed5i m\u1eafc ph\u1ea3i t\u1ea1i c\u1ed9ng \u0111\u1ed3ng v\u00e0 vi\u00eam ph\u1ed5i b\u1ec7nh vi\u1ec7n.<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u c\u00f3 bi\u1ebfn ch\u1ee9ng.<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n \u1ed5 b\u1ee5ng c\u00f3 bi\u1ebfn ch\u1ee9ng.<\/li>\n<li>Vi\u00eam m\u00e0ng n\u00e3o do vi khu\u1ea9n c\u1ea5p t\u00ednh.<\/li>\n<li>S\u1ed1t do gi\u1ea3m b\u1ea1ch c\u1ea7u.<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n trong v\u00e0 sau sinh.<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n da v\u00e0 m\u00f4 m\u1ec1m c\u00f3 bi\u1ebfn ch\u1ee9ng.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Tiepanem Meropenem 1g<\/h2>\n<ul>\n<li>Ng\u01b0\u1eddi l\u1edbn:\n<ul>\n<li>Nhi\u1ec5m khu\u1ea9n da v\u00e0 c\u1ea5u tr\u00fac da, nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u, nhi\u1ec5m khu\u1ea9n ph\u1ee5 khoa, vi\u00eam ph\u1ed5i: 500mg m\u1ed7i 8 gi\u1edd.<\/li>\n<li>Vi\u00eam ph\u00fac m\u1ea1c, vi\u00eam ph\u1ed5i b\u1ec7nh vi\u1ec7n, nhi\u1ec5m khu\u1ea9n huy\u1ebft, nhi\u1ec5m khu\u1ea9n \u1edf b\u1ec7nh nh\u00e2n suy gi\u1ea3m b\u1ea1ch c\u1ea7u: 1g m\u1ed7i 8 gi\u1edd.<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n \u1edf b\u1ec7nh nh\u00e2n x\u01a1 h\u00f3a nang, vi\u00eam m\u00e0ng n\u00e3o: 2g m\u1ed7i 8 gi\u1edd.<\/li>\n<\/ul>\n<\/li>\n<li>B\u1ec7nh nh\u00e2n suy th\u1eadn: Li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh d\u1ef1a tr\u00ean \u0111\u1ed9 thanh th\u1ea3i creatinin:\n<ul>\n<li>\u0110\u1ed9 thanh th\u1ea3i creatinin 26 \u2013 50 ml\/ph\u00fat: Li\u1ec1u t\u01b0\u01a1ng \u1ee9ng (500mg, 1g ho\u1eb7c 2g) m\u1ed7i 12 gi\u1edd.<\/li>\n<li>\u0110\u1ed9 thanh th\u1ea3i creatinin 10 \u2013 25 ml\/ph\u00fat: N\u1eeda li\u1ec1u t\u01b0\u01a1ng \u1ee9ng m\u1ed7i 12 gi\u1edd.<\/li>\n<li>\u0110\u1ed9 thanh th\u1ea3i creatinin d\u01b0\u1edbi 10 ml\/ph\u00fat: N\u1eeda li\u1ec1u t\u01b0\u01a1ng \u1ee9ng m\u1ed7i 24 gi\u1edd.<\/li>\n<\/ul>\n<\/li>\n<li>Tr\u1ebb em:\n<ul>\n<li>Tr\u1ebb t\u1eeb 3 th\u00e1ng \u0111\u1ebfn 12 tu\u1ed5i: 10 \u2013 20mg\/kg c\u00e2n n\u1eb7ng m\u1ed7i 8 gi\u1edd.<\/li>\n<li>Tr\u1ebb t\u1eeb 50kg tr\u1edf l\u00ean: S\u1eed d\u1ee5ng li\u1ec1u nh\u01b0 ng\u01b0\u1eddi l\u1edbn.<\/li>\n<li>Vi\u00eam m\u00e0ng n\u00e3o: 40mg\/kg c\u00e2n n\u1eb7ng m\u1ed7i 8 gi\u1edd.<\/li>\n<\/ul>\n<\/li>\n<li>Li\u1ec1u d\u00f9ng c\u1ee5 th\u1ec3 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh b\u1edfi b\u00e1c s\u0129 t\u00f9y thu\u1ed9c v\u00e0o m\u1ee9c \u0111\u1ed9 nhi\u1ec5m khu\u1ea9n v\u00e0 t\u00ecnh tr\u1ea1ng s\u1ee9c kh\u1ecfe c\u1ee7a t\u1eebng b\u1ec7nh nh\u00e2n.<\/li>\n<\/ul>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Tiepanem Meropenem 1g<\/h2>\n<p>Thu\u1ed1c Tiepanem 1g \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng ti\u00eam t\u0129nh m\u1ea1ch v\u00e0 quy tr\u00ecnh ti\u00eam truy\u1ec1n ph\u1ea3i \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi nh\u00e2n vi\u00ean y t\u1ebf c\u00f3 chuy\u00ean m\u00f4n.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Tiepanem Meropenem 1g trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Tiepanem 1g cho c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng sau:<\/p>\n<ul>\n<li>Ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn v\u1edbi meropenem, b\u1ea5t k\u1ef3 thu\u1ed1c n\u00e0o thu\u1ed9c nh\u00f3m carbapenem ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>Ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7 khi s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c nh\u00f3m beta-lactam.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Tiepanem Meropenem 1g<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Kh\u00f4ng tr\u1ed9n l\u1eabn Tiepanem 1g v\u1edbi b\u1ea5t k\u1ef3 thu\u1ed1c n\u00e0o kh\u00e1c ngo\u00e0i dung d\u1ecbch natri clorid 0,9% ho\u1eb7c glucose 5%.<\/li>\n<li>C\u1ea7n theo d\u00f5i n\u1ed3ng \u0111\u1ed9 bilirubin v\u00e0 transaminase \u1edf b\u1ec7nh nh\u00e2n c\u00f3 b\u1ec7nh l\u00fd gan trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb v\u1edbi Tiepanem 1g.<\/li>\n<li>Theo d\u00f5i ch\u1eb7t ch\u1ebd b\u1ec7nh nh\u00e2n trong su\u1ed1t qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 ph\u00e1t hi\u1ec7n s\u1edbm c\u00e1c d\u1ea5u hi\u1ec7u b\u1ed9i nhi\u1ec5m.<\/li>\n<li>Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng thu\u1ed1c cho b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, \u0111\u1eb7c bi\u1ec7t l\u00e0 vi\u00eam \u0111\u1ea1i tr\u00e0ng, do Tiepanem c\u00f3 th\u1ec3 g\u00e2y vi\u00eam \u0111\u1ea1i tr\u00e0ng gi\u1ea3 m\u1ea1c v\u1edbi bi\u1ec3u hi\u1ec7n ti\u00eau ch\u1ea3y.<\/li>\n<li>Khi \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p do Pseudomonas aeruginosa, c\u1ea7n th\u1eadn tr\u1ecdng v\u00e0 th\u01b0\u1eddng xuy\u00ean ki\u1ec3m tra \u0111\u1ed9 nh\u1ea1y c\u1ea3m c\u1ee7a vi khu\u1ea9n.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>C\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u00f3 th\u1ec3 x\u1ea3y ra khi s\u1eed d\u1ee5ng Tiepanem 1g bao g\u1ed3m:<\/p>\n<ul>\n<li>Th\u01b0\u1eddng g\u1eb7p: T\u0103ng s\u1ed1 l\u01b0\u1ee3ng ti\u1ec3u c\u1ea7u, \u0111au \u0111\u1ea7u, t\u00e1o b\u00f3n, ti\u00eau ch\u1ea3y, bu\u1ed3n n\u00f4n, n\u00f4n, ph\u00e1t ban, vi\u00eam v\u00e0 \u0111au t\u1ea1i v\u1ecb tr\u00ed ti\u00eam.<\/li>\n<li>\u00cdt g\u1eb7p: Nhi\u1ec5m n\u1ea5m Candida, gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u, c\u1ea3m gi\u00e1c b\u1ea5t th\u01b0\u1eddng (d\u1ecb c\u1ea3m), t\u0103ng bilirubin huy\u1ebft thanh, vi\u00eam t\u0129nh m\u1ea1ch huy\u1ebft kh\u1ed1i.<\/li>\n<li>Hi\u1ebfm g\u1eb7p: M\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t, ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng nghi\u00eam tr\u1ecdng (ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7), co gi\u1eadt, vi\u00eam \u0111\u1ea1i tr\u00e0ng gi\u1ea3 m\u1ea1c, h\u1ed9i ch\u1ee9ng Stevens-Johnson.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Aminoglycosid: C\u00f3 th\u1ec3 hi\u1ec7p \u0111\u1ed3ng t\u00e1c d\u1ee5ng kh\u00e1ng khu\u1ea9n tr\u00ean Pseudomonas aeruginosa.<\/li>\n<li>Probenecid: L\u00e0m gi\u1ea3m s\u1ef1 b\u00e0i ti\u1ebft meropenem qua th\u1eadn, d\u1eabn \u0111\u1ebfn t\u0103ng n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00e1u v\u00e0 k\u00e9o d\u00e0i th\u1eddi gian th\u1ea3i tr\u1eeb. N\u00ean tr\u00e1nh d\u00f9ng \u0111\u1ed3ng th\u1eddi.<\/li>\n<li>Acid valproic: Meropenem c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 acid valproic xu\u1ed1ng d\u01b0\u1edbi m\u1ee9c \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3, c\u1ea7n th\u1eadn tr\u1ecdng khi ph\u1ed1i h\u1ee3p v\u1edbi acid valproic.<\/li>\n<li>Thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u (warfarin): Meropenem c\u00f3 th\u1ec3 l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng ch\u1ed1ng \u0111\u00f4ng c\u1ee7a warfarin, c\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>C\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng v\u00e0 ch\u1ec9 d\u00f9ng khi l\u1ee3i \u00edch \u0111i\u1ec1u tr\u1ecb v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1 ti\u1ec1m \u1ea9n cho thai nhi ho\u1eb7c tr\u1ebb b\u00fa m\u1eb9, d\u01b0\u1edbi s\u1ef1 gi\u00e1m s\u00e1t c\u1ee7a b\u00e1c s\u0129.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Khi s\u1eed d\u1ee5ng qu\u00e1 li\u1ec1u Tiepanem 1g (meropenem), c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 tr\u1edf n\u00ean nghi\u00eam tr\u1ecdng h\u01a1n. Tuy nhi\u00ean, c\u00e1c tri\u1ec7u ch\u1ee9ng n\u00e0y th\u01b0\u1eddng gi\u1ea3m \u0111i khi ng\u1eebng thu\u1ed1c ho\u1eb7c gi\u1ea3m li\u1ec1u. Trong tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u, \u0111i\u1ec1u tr\u1ecb ch\u1ee7 y\u1ebfu l\u00e0 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 h\u1ed7 tr\u1ee3. \u1ede b\u1ec7nh nh\u00e2n c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng, thu\u1ed1c s\u1ebd \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb nhanh ch\u00f3ng qua th\u1eadn. Th\u1ea9m t\u00e1ch m\u00e1u c\u00f3 th\u1ec3 gi\u00fap lo\u1ea1i b\u1ecf meropenem v\u00e0 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a n\u00f3.<\/p>\n<h2>S\u1ea3n ph\u1ea9m thay th\u1ebf thu\u1ed1c Tiepanem Meropenem 1g?<\/h2>\n<p><a href=\"https:\/\/vnras.com\/drug\/meropenem-kabi-1g\/\">Meropenem Kabi 1g<\/a> c\u00f3 th\u00e0nh ph\u1ea7n Meropenem 1g, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Facta Farmaceutici S.p.A, d\u00f9ng \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n cho ng\u01b0\u1edbi l\u1edbn v\u00e0 tr\u1ebb em tr\u00ean 3 th\u00e1ng tu\u1ed5i.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Nadine A Steffens, Estevan S Zimmermann, Sabrina M Nichelle, Nat\u00e1lia Brucker. Meropenem use and therapeutic drug monitoring in clinical practice: a literature review, truy c\u1eadp ng\u00e0y 06 th\u00e1ng 05 n\u0103m 2025 t\u1eeb<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33533509\/\" rel=\"noopener\"> https:\/\/pubmed.ncbi.nlm.nih.gov\/33533509\/ <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>M\u1ed7i l\u1ecd b\u1ed9t pha ti\u00eam truy\u1ec1n Tiepanem Meropenem 1g ch\u1ee9a th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Meropenem (d\u01b0\u1edbi d\u1ea1ng Meropenem trihydrat) 1g v\u00e0 t\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7. Meropenem l\u00e0 m\u1ed9t kh\u00e1ng sinh t\u1ed5ng h\u1ee3p thu\u1ed9c nh\u00f3m carbapenem<\/p>\n","protected":false},"author":1,"featured_media":117910,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-117907","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/117907","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=117907"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/117910"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=117907"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=117907"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=117907"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}