{"id":117855,"date":"2025-05-06T11:38:53","date_gmt":"2025-05-06T04:38:53","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=117855"},"modified":"2026-03-06T08:09:53","modified_gmt":"2026-03-06T01:09:53","slug":"celosti-200mg-dhg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/celosti-200mg-dhg\/","title":{"rendered":"Celosti 200mg DHG"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Celosti 200mg DHG \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng Ty C\u1ed5 Ph\u1ea7n D\u01b0\u1ee3c H\u1eadu Giang \u2013 Chi nh\u00e1nh nh\u00e0 m\u00e1y d\u01b0\u1ee3c ph\u1ea9m DHG t\u1ea1i H\u1eadu Giang, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110268423 (VD-25557-16).<\/strong><\/p>\n<h2>Celosti 200mg DHG l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean nang c\u1ee9ng <strong>Celosti 200 DHG<\/strong> ch\u1ee9a:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t: <strong>Celecoxib<\/strong> h\u00e0m l\u01b0\u1ee3ng 200mg.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110268423 (VD-25557-16)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 2 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Celosti 200mg DHG<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Celecoxib l\u00e0 m\u1ed9t ho\u1ea1t ch\u1ea5t c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc enzyme cyclooxygenase-2 (COX-2). Th\u00f4ng qua c\u01a1 ch\u1ebf n\u00e0y, thu\u1ed1c gi\u00fap gi\u1ea3m vi\u00eam, h\u1ea1 s\u1ed1t v\u00e0 gi\u1ea3m \u0111au. B\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf COX-2, celecoxib l\u00e0m gi\u1ea3m qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p prostaglandin, l\u00e0 c\u00e1c ch\u1ea5t trung gian g\u00e2y vi\u00eam. Do \u00edt t\u00e1c \u0111\u1ed9ng l\u00ean enzyme COX-1, celecoxib \u0111\u01b0\u1ee3c cho l\u00e0 c\u00f3 nguy c\u01a1 th\u1ea5p h\u01a1n g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean ni\u00eam m\u1ea1c d\u1ea1 d\u00e0y v\u00e0 ch\u1ee9c n\u0103ng ti\u1ec3u c\u1ea7u so v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00f4ng steroid (NSAIDs) truy\u1ec1n th\u1ed1ng.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu: Celecoxib \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh ch\u00f3ng sau khi u\u1ed1ng. Khi b\u1ee5ng \u0111\u00f3i, n\u1ed3ng \u0111\u1ed9 cao nh\u1ea5t c\u1ee7a thu\u1ed1c trong m\u00e1u th\u01b0\u1eddng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau kho\u1ea3ng 2 \u0111\u1ebfn 3 gi\u1edd sau khi u\u1ed1ng m\u1ed9t li\u1ec1u duy nh\u1ea5t 200mg. N\u1ed3ng \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh trong huy\u1ebft t\u01b0\u01a1ng th\u01b0\u1eddng \u0111\u1ea1t \u0111\u01b0\u1ee3c trong v\u00f2ng 5 ng\u00e0y s\u1eed d\u1ee5ng li\u00ean t\u1ee5c m\u00e0 kh\u00f4ng c\u00f3 d\u1ea5u hi\u1ec7u t\u00edch l\u0169y \u0111\u00e1ng k\u1ec3. Sinh kh\u1ea3 d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng c\u1ee7a vi\u00ean nang celecoxib l\u00e0 kho\u1ea3ng 99%.<\/li>\n<li>Ph\u00e2n b\u1ed1: Kho\u1ea3ng 97% celecoxib g\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng. Thu\u1ed1c kh\u00f4ng c\u00f3 xu h\u01b0\u1edbng g\u1eafn k\u1ebft \u01b0u ti\u00ean v\u1edbi t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u.<\/li>\n<li>Chuy\u1ec3n h\u00f3a: Celecoxib ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a \u1edf gan th\u00f4ng qua h\u1ec7 th\u1ed1ng enzyme cytochrome P450 2C9. C\u00e1c nghi\u00ean c\u1ee9u \u0111\u00e3 x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c ba ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00f4ng c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf COX-1 ho\u1eb7c COX-2 trong huy\u1ebft t\u01b0\u01a1ng ng\u01b0\u1eddi, bao g\u1ed3m m\u1ed9t alcol b\u1eadc nh\u1ea5t, m\u1ed9t acid carboxylic v\u00e0 m\u1ed9t d\u1ea1ng k\u1ebft h\u1ee3p glucuronide c\u1ee7a n\u00f3.<\/li>\n<li>Th\u1ea3i tr\u1eeb: Celecoxib \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a \u1edf gan, v\u1edbi d\u01b0\u1edbi 1% li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua n\u01b0\u1edbc ti\u1ec3u \u1edf d\u1ea1ng kh\u00f4ng \u0111\u1ed5i. Th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a celecoxib sau khi u\u1ed1ng l\u00e0 kho\u1ea3ng 8 \u0111\u1ebfn 12 gi\u1edd v\u00e0 c\u00f3 th\u1ec3 k\u00e9o d\u00e0i h\u01a1n \u1edf nh\u1eefng ng\u01b0\u1eddi b\u1ecb suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn ho\u1eb7c gan. Kho\u1ea3ng 27% li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 57% qua ph\u00e2n, trong \u0111\u00f3 d\u01b0\u1edbi 3% l\u00e0 \u1edf d\u1ea1ng thu\u1ed1c kh\u00f4ng b\u1ecb chuy\u1ec3n h\u00f3a.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Celosti 200mg DHG \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<figure id=\"attachment_117856\" aria-describedby=\"caption-attachment-117856\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-117856\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Celosti-200mg-DHG.jpg\" alt=\"Celosti 200mg DHG \u0111i\u1ec1u tr\u1ecb vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Celosti-200mg-DHG.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Celosti-200mg-DHG-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Celosti-200mg-DHG-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/05\/Celosti-200mg-DHG-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-117856\" class=\"wp-caption-text\">Celosti 200mg DHG \u0111i\u1ec1u tr\u1ecb vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p<\/figcaption><\/figure>\n<ul>\n<li>Gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh tho\u00e1i h\u00f3a kh\u1edbp (osteoarthritis &#8211; OA) v\u00e0 vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p (rheumatoid arthritis &#8211; RA).<\/li>\n<li>H\u1ed7 tr\u1ee3 l\u00e0m gi\u1ea3m nh\u1eb9 c\u00e1c d\u1ea5u hi\u1ec7u v\u00e0 tri\u1ec7u ch\u1ee9ng c\u1ee7a vi\u00eam kh\u1edbp t\u1ef1 ph\u00e1t \u1edf tr\u1ebb em (juvenile idiopathic arthritis &#8211; JIA) cho tr\u1ebb t\u1eeb 2 tu\u1ed5i tr\u1edf l\u00ean v\u1edbi c\u00e2n n\u1eb7ng t\u1ed1i thi\u1ec3u 10 kg.<\/li>\n<li>Gi\u1ea3m nh\u1eb9 c\u00e1c d\u1ea5u hi\u1ec7u v\u00e0 tri\u1ec7u ch\u1ee9ng c\u1ee7a vi\u00eam c\u1ed9t s\u1ed1ng d\u00ednh kh\u1edbp (ankylosing spondylitis).<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb \u0111au b\u1ee5ng kinh nguy\u00ean ph\u00e1t (primary dysmenorrhea).<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Celosti 200mg DHG<\/h2>\n<h3>Ng\u01b0\u1eddi l\u1edbn<\/h3>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng tho\u00e1i h\u00f3a kh\u1edbp: 200mg m\u1ed9t l\u1ea7n m\u1ed7i ng\u00e0y ho\u1eb7c 100mg hai l\u1ea7n m\u1ed7i ng\u00e0y.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p: 100mg ho\u1eb7c 200mg hai l\u1ea7n m\u1ed7i ng\u00e0y.<\/li>\n<li>Vi\u00eam c\u1ed9t s\u1ed1ng d\u00ednh kh\u1edbp: 200mg m\u1ed9t l\u1ea7n m\u1ed7i ng\u00e0y ho\u1eb7c 100mg hai l\u1ea7n m\u1ed7i ng\u00e0y. M\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 \u0111\u00e1p \u1ee9ng t\u1ed1t h\u01a1n v\u1edbi t\u1ed5ng li\u1ec1u 400mg m\u1ed7i ng\u00e0y.<\/li>\n<li>Ki\u1ec3m so\u00e1t \u0111au c\u1ea5p t\u00ednh: Li\u1ec1u kh\u1edfi \u0111\u1ea7u 400mg, c\u00f3 th\u1ec3 d\u00f9ng th\u00eam 200mg trong ng\u00e0y \u0111\u1ea7u ti\u00ean n\u1ebfu c\u1ea7n. Nh\u1eefng ng\u00e0y ti\u1ebfp theo, li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 200mg hai l\u1ea7n m\u1ed7i ng\u00e0y khi c\u1ea7n.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb \u0111au b\u1ee5ng kinh nguy\u00ean ph\u00e1t: Li\u1ec1u kh\u1edfi \u0111\u1ea7u 400mg, c\u00f3 th\u1ec3 d\u00f9ng th\u00eam 200mg trong ng\u00e0y \u0111\u1ea7u ti\u00ean n\u1ebfu c\u1ea7n. Nh\u1eefng ng\u00e0y ti\u1ebfp theo, li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 200mg hai l\u1ea7n m\u1ed7i ng\u00e0y khi c\u1ea7n.<\/li>\n<li>Li\u1ec1u th\u00f4ng th\u01b0\u1eddng \u1edf ng\u01b0\u1eddi l\u1edbn: 400mg cho li\u1ec1u \u0111\u1ea7u ti\u00ean, sau \u0111\u00f3 200mg n\u1ebfu c\u1ea7n trong ng\u00e0y \u0111\u1ea7u. \u0110\u1ec3 ti\u1ebfp t\u1ee5c gi\u1ea3m \u0111au, c\u00f3 th\u1ec3 d\u00f9ng 200mg hai l\u1ea7n m\u1ed7i ng\u00e0y n\u1ebfu c\u1ea7n.<\/li>\n<\/ul>\n<h3>Ng\u01b0\u1eddi c\u00f3 chuy\u1ec3n h\u00f3a k\u00e9m CYP2C9<\/h3>\n<p>C\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng celecoxib v\u00e0 n\u00ean b\u1eaft \u0111\u1ea7u v\u1edbi n\u1eeda li\u1ec1u khuy\u1ebfn c\u00e1o th\u1ea5p nh\u1ea5t.<\/p>\n<h3>D\u00f9ng k\u1ebft h\u1ee3p v\u1edbi fluconazole<\/h3>\n<p>N\u00ean d\u00f9ng n\u1eeda li\u1ec1u khuy\u1ebfn c\u00e1o.<\/p>\n<h3>Tr\u1ebb em t\u1eeb 2 tu\u1ed5i tr\u1edf l\u00ean<\/h3>\n<p>Vi\u00eam kh\u1edbp t\u1ef1 ph\u00e1t thi\u1ebfu ni\u00ean:<\/p>\n<ul>\n<li>C\u00e2n n\u1eb7ng 10kg \u0111\u1ebfn 25kg: 50mg hai l\u1ea7n m\u1ed7i ng\u00e0y.<\/li>\n<li>C\u00e2n n\u1eb7ng tr\u00ean 25kg: 100mg hai l\u1ea7n m\u1ed7i ng\u00e0y.<\/li>\n<\/ul>\n<h3>Ng\u01b0\u1eddi cao tu\u1ed5i<\/h3>\n<p>Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u \u1edf ng\u01b0\u1eddi tr\u00ean 65 tu\u1ed5i. Tuy nhi\u00ean, \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi cao tu\u1ed5i c\u00f3 c\u00e2n n\u1eb7ng d\u01b0\u1edbi 50kg, n\u00ean b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u1edbi li\u1ec1u khuy\u1ebfn c\u00e1o th\u1ea5p nh\u1ea5t.<\/p>\n<h3>Ng\u01b0\u1eddi suy gan<\/h3>\n<p>Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u \u1edf b\u1ec7nh nh\u00e2n suy gan nh\u1eb9. \u1ede b\u1ec7nh nh\u00e2n suy gan v\u1eeba, n\u00ean d\u00f9ng n\u1eeda li\u1ec1u. Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c \u1edf b\u1ec7nh nh\u00e2n suy gan n\u1eb7ng.<\/p>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Celosti 200mg DHG<\/h2>\n<p>Thu\u1ed1c Celosti 200mg DHG d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng, c\u00f3 th\u1ec3 u\u1ed1ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng v\u1edbi th\u1ee9c \u0103n. \u0110\u1ed1i v\u1edbi ng\u01b0\u1eddi b\u1ec7nh g\u1eb7p kh\u00f3 kh\u0103n khi nu\u1ed1t vi\u00ean nang, c\u00f3 th\u1ec3 m\u1edf vi\u00ean nang v\u00e0 tr\u1ed9n thu\u1ed1c b\u00ean trong v\u1edbi m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf sinh t\u1ed1, ch\u00e1o, s\u1eefa chua ho\u1eb7c chu\u1ed1i nghi\u1ec1n \u0111\u1ec3 d\u1ec5 u\u1ed1ng h\u01a1n.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Celosti 200mg DHG trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>C\u00f3 ti\u1ec1n s\u1eed m\u1eabn c\u1ea3m v\u1edbi celecoxib ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>C\u00f3 ti\u1ec1n s\u1eed m\u1eabn c\u1ea3m v\u1edbi c\u00e1c sulfonamid.<\/li>\n<li>\u0110\u00e3 t\u1eebng b\u1ecb hen suy\u1ec5n, n\u1ed5i m\u1ec1 \u0111ay ho\u1eb7c c\u00e1c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng kh\u00e1c sau khi d\u00f9ng aspirin ho\u1eb7c c\u00e1c thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00f4ng steroid kh\u00e1c.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb \u0111au sau ph\u1eabu thu\u1eadt gh\u00e9p m\u1ea1ch v\u00e0nh nh\u00e2n t\u1ea1o (CABG).<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Celosti 200mg DHG<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Nguy c\u01a1 tim m\u1ea1ch: Thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 huy\u1ebft kh\u1ed1i, nh\u1ed3i m\u00e1u c\u01a1 tim, \u0111\u1ed9t qu\u1ef5, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi d\u00f9ng li\u1ec1u cao, k\u00e9o d\u00e0i v\u00e0 c\u00f3 s\u1eb5n y\u1ebfu t\u1ed1 nguy c\u01a1 tim m\u1ea1ch ho\u1eb7c ti\u1ec1n s\u1eed b\u1ec7nh tim. C\u1ea7n d\u00f9ng li\u1ec1u th\u1ea5p nh\u1ea5t, th\u1eddi gian ng\u1eafn nh\u1ea5t v\u00e0 theo d\u00f5i ch\u1eb7t ch\u1ebd.<\/li>\n<li>T\u0103ng huy\u1ebft \u00e1p, \u1ee9 d\u1ecbch, ph\u00f9: C\u1ea7n theo d\u00f5i huy\u1ebft \u00e1p v\u00e0 t\u00ecnh tr\u1ea1ng \u1ee9 d\u1ecbch \u1edf b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed t\u0103ng huy\u1ebft \u00e1p ho\u1eb7c suy tim.<\/li>\n<li>T\u00e1c \u0111\u1ed9ng ti\u00eau h\u00f3a: T\u0103ng nguy c\u01a1 th\u1ee7ng, lo\u00e9t, ch\u1ea3y m\u00e1u \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi l\u1edbn tu\u1ed5i, c\u00f3 ti\u1ec1n s\u1eed b\u1ec7nh tim m\u1ea1ch ho\u1eb7c \u0111ang d\u00f9ng aspirin, corticosteroid.<\/li>\n<li>T\u00e1c \u0111\u1ed9ng th\u1eadn: C\u00f3 th\u1ec3 g\u00e2y \u0111\u1ed9c th\u1eadn, c\u1ea7n th\u1eadn tr\u1ecdng \u1edf ng\u01b0\u1eddi m\u1ea5t n\u01b0\u1edbc ho\u1eb7c c\u00f3 b\u1ec7nh th\u1eadn ti\u1ebfn tri\u1ec3n v\u00e0 theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn.<\/li>\n<li>Kh\u00f4ng dung n\u1ea1p lactose: Kh\u00f4ng d\u00f9ng cho ng\u01b0\u1eddi c\u00f3 v\u1ea5n \u0111\u1ec1 v\u1ec1 dung n\u1ea1p lactose do t\u00e1 d\u01b0\u1ee3c trong thu\u1ed1c.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<h3>Th\u01b0\u1eddng g\u1eb7p<\/h3>\n<ul>\n<li>Ti\u00eau h\u00f3a: \u0110au b\u1ee5ng, ti\u00eau ch\u1ea3y, kh\u00f3 ti\u00eau, \u0111\u1ea7y h\u01a1i, bu\u1ed3n n\u00f4n.<\/li>\n<li>Tim m\u1ea1ch: Nh\u1ed3i m\u00e1u c\u01a1 tim, \u0111au th\u1eaft ng\u1ef1c.<\/li>\n<li>R\u1ed1i lo\u1ea1n m\u1ea1ch: T\u0103ng huy\u1ebft \u00e1p.<\/li>\n<li>H\u00f4 h\u1ea5p: Kh\u00f3 th\u1edf.<\/li>\n<li>Th\u1ea7n kinh: M\u1ea5t ng\u1ee7, ch\u00f3ng m\u1eb7t, nh\u1ee9c \u0111\u1ea7u.<\/li>\n<li>Da: Ph\u00e1t ban.<\/li>\n<li>R\u1ed1i lo\u1ea1n chung: \u0110au l\u01b0ng, ph\u00f9 ngo\u1ea1i bi\u00ean.<\/li>\n<li>Nhi\u1ec5m tr\u00f9ng v\u00e0 nhi\u1ec5m k\u00fd sinh: Nhi\u1ec5m khu\u1ea9n tai, nhi\u1ec5m n\u1ea5m.<\/li>\n<\/ul>\n<h3>\u00cdt g\u1eb7p<\/h3>\n<ul>\n<li>Nhi\u1ec5m tr\u00f9ng v\u00e0 nhi\u1ec5m k\u00fd sinh: Nhi\u1ec5m Helicobacter, Herpes zoster, vi\u00eam l\u1ee3i, vi\u00eam tai trong.<\/li>\n<li>Kh\u1ed1i u l\u00e0nh t\u00ednh: U m\u1ee1.<\/li>\n<li>Th\u1ea7n kinh: R\u1ed1i lo\u1ea1n gi\u1ea5c ng\u1ee7, nh\u1ed3i m\u00e1u n\u00e3o.<\/li>\n<li>M\u1eaft: Xu\u1ea5t huy\u1ebft k\u1ebft m\u1ea1c.<\/li>\n<li>Tai: Gi\u1ea3m th\u00ednh l\u1ef1c.<\/li>\n<li>R\u1ed1i lo\u1ea1n m\u1ea1ch: T\u1ee5 m\u00e1u.<\/li>\n<li>H\u00f4 h\u1ea5p: Kh\u00f3 ph\u00e1t \u00e2m.<\/li>\n<\/ul>\n<h3>Hi\u1ebfm g\u1eb7p<\/h3>\n<ul>\n<li>Tim m\u1ea1ch: Ng\u1ea5t, suy tim sung huy\u1ebft, rung th\u1ea5t, vi\u00eam t\u0129nh m\u1ea1ch huy\u1ebft kh\u1ed1i, vi\u00eam m\u1ea1ch.<\/li>\n<li>Ti\u00eau h\u00f3a: ch\u1ea3y m\u00e1u \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, vi\u00eam \u0111\u1ea1i tr\u00e0ng ch\u1ea3y m\u00e1u, th\u1ee7ng th\u1ef1c qu\u1ea3n.<\/li>\n<li>Gan m\u1eadt: B\u1ec7nh s\u1ecfi m\u1eadt, v\u00e0ng da, vi\u00eam gan, suy gan.<\/li>\n<li>M\u00e1u v\u00e0 h\u1ec7 b\u1ea1ch huy\u1ebft: Gi\u1ea3m ti\u1ec3u c\u1ea7u, m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t, gi\u1ea3m b\u1ea1ch c\u1ea7u.<\/li>\n<li>Chuy\u1ec3n h\u00f3a: Gi\u1ea3m glucose huy\u1ebft.<\/li>\n<li>Th\u1ea7n kinh: hoang t\u01b0\u1edfng.<\/li>\n<li>Th\u1eadn: Suy th\u1eadn c\u1ea5p, vi\u00eam th\u1eadn k\u1ebd.<\/li>\n<li>Da: Ban \u0111\u1ecf \u0111a d\u1ea1ng, vi\u00eam da tr\u00f3c, h\u1ed9i ch\u1ee9ng Stevens &#8211; Johnson.<\/li>\n<li>R\u1ed1i lo\u1ea1n chung: Nhi\u1ec5m khu\u1ea9n, ph\u1ea3n \u1ee9ng d\u1ea1ng ph\u1ea3n v\u1ec7, ph\u00f9 m\u1ea1ch.<\/li>\n<li>Tim m\u1ea1ch: Nguy c\u01a1 huy\u1ebft kh\u1ed1i tim m\u1ea1ch.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>\u0110\u00e3 c\u00f3 b\u00e1o c\u00e1o v\u1ec1 c\u00e1c bi\u1ebfn ch\u1ee9ng ch\u1ea3y m\u00e1u k\u1ebft h\u1ee3p v\u1edbi t\u0103ng th\u1eddi gian prothrombin \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n cao tu\u1ed5i khi d\u00f9ng \u0111\u1ed3ng th\u1eddi celecoxib v\u1edbi warfarin.<\/li>\n<li>Celecoxib c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m s\u1ef1 thanh th\u1ea3i th\u1eadn c\u1ee7a lithium, d\u1eabn \u0111\u1ebfn t\u0103ng n\u1ed3ng \u0111\u1ed9 lithium trong huy\u1ebft t\u01b0\u01a1ng.<\/li>\n<li>S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi celecoxib v\u00e0 aspirin c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 lo\u00e9t \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/li>\n<li>Celecoxib c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n angiotensin (ACE inhibitors).<\/li>\n<li>Celecoxib c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 \u0111\u1ed9c t\u00ednh tr\u00ean th\u1eadn c\u1ee7a cyclosporin.<\/li>\n<li>D\u00f9ng \u0111\u1ed3ng th\u1eddi celecoxib v\u1edbi fluconazole ho\u1eb7c ketoconazole c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn t\u0103ng n\u1ed3ng \u0111\u1ed9 celecoxib trong huy\u1ebft t\u01b0\u01a1ng.<\/li>\n<li>Celecoxib c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a dextromethorphan v\u00e0 metoprolol.<\/li>\n<li>Celecoxib c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng l\u1ee3i ti\u1ec3u natri c\u1ee7a furosemide v\u00e0 c\u00e1c thiazide.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Tr\u00e1nh d\u00f9ng trong qu\u00fd ba thai k\u1ef3 do nguy c\u01a1 cho thai nhi. C\u00e2n nh\u1eafc ng\u1eebng cho con b\u00fa do thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n cho tr\u1ebb.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<ul>\n<li>Tri\u1ec7u ch\u1ee9ng: Qu\u00e1 li\u1ec1u thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00f4ng steroid c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 ng\u1ee7 g\u00e0, l\u01a1 m\u01a1, bu\u1ed3n n\u00f4n, n\u00f4n v\u00e0 \u0111au v\u00f9ng th\u01b0\u1ee3ng v\u1ecb. C\u00e1c tri\u1ec7u ch\u1ee9ng n\u00e0y th\u01b0\u1eddng c\u00f3 th\u1ec3 h\u1ed3i ph\u1ee5c khi \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3. C\u00e1c tri\u1ec7u ch\u1ee9ng \u00edt g\u1eb7p h\u01a1n bao g\u1ed3m t\u0103ng huy\u1ebft \u00e1p, suy th\u1eadn c\u1ea5p, \u1ee9c ch\u1ebf h\u00f4 h\u1ea5p v\u00e0 h\u00f4n m\u00ea. C\u00e1c ph\u1ea3n \u1ee9ng d\u1ea1ng ph\u1ea3n v\u1ec7 c\u0169ng \u0111\u00e3 \u0111\u01b0\u1ee3c ghi nh\u1eadn v\u1edbi li\u1ec1u \u0111i\u1ec1u tr\u1ecb c\u1ee7a NSAIDs v\u00e0 c\u00f3 th\u1ec3 x\u1ea3y ra khi d\u00f9ng qu\u00e1 li\u1ec1u.<\/li>\n<li>X\u1eed tr\u00ed: \u0110i\u1ec1u tr\u1ecb ch\u1ee7 y\u1ebfu l\u00e0 h\u1ed7 tr\u1ee3 v\u00e0 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng. Hi\u1ec7n ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u cho celecoxib. Trong v\u00f2ng 4 gi\u1edd \u0111\u1ea7u sau khi d\u00f9ng qu\u00e1 li\u1ec1u, c\u00f3 th\u1ec3 c\u00e2n nh\u1eafc vi\u1ec7c g\u00e2y n\u00f4n v\u00e0\/ho\u1eb7c s\u1eed d\u1ee5ng than ho\u1ea1t t\u00ednh, v\u00e0\/ho\u1eb7c thu\u1ed1c nhu\u1eadn tr\u00e0ng th\u1ea9m th\u1ea5u cho nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 bi\u1ec3u hi\u1ec7n b\u1ec7nh l\u00fd ho\u1eb7c \u0111\u00e3 u\u1ed1ng m\u1ed9t l\u01b0\u1ee3ng thu\u1ed1c l\u1edbn.<\/li>\n<\/ul>\n<h2>S\u1ea3n ph\u1ea9m thay th\u1ebf Celosti 200mg DHG?<\/h2>\n<p><a href=\"https:\/\/vnras.com\/drug\/celebrex\/\">Celebrex<\/a> c\u00f3 th\u00e0nh ph\u1ea7n Celecoxib 200mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Pfizer Limited, d\u00f9ng \u0111i\u1ec1u tr\u1ecb vi\u00eam kh\u1edbp.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Kate Rowan-Robinson (2019) Celecoxib for osteoarthritis, truy c\u1eadp ng\u00e0y 06 th\u00e1ng 05 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31604050\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/31604050\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>M\u1ed7i vi\u00ean nang c\u1ee9ng Celosti 200 DHG ch\u1ee9a ho\u1ea1t ch\u1ea5t Celecoxib h\u00e0m l\u01b0\u1ee3ng 200mg v\u00e0 t\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean. Celecoxib l\u00e0 m\u1ed9t ho\u1ea1t ch\u1ea5t c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc enzyme cyclooxygenase-2 (COX-2).<\/p>\n","protected":false},"author":1,"featured_media":117862,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-117855","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/117855","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=117855"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/117862"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=117855"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=117855"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=117855"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}