{"id":114100,"date":"2025-04-08T15:11:40","date_gmt":"2025-04-08T08:11:40","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=114100"},"modified":"2025-07-24T13:16:47","modified_gmt":"2025-07-24T06:16:47","slug":"graxostat-40mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/graxostat-40mg\/","title":{"rendered":"Graxostat 40mg"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, <\/b>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Graxostat 40mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Gracure Pharmaceuticals Ltd, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 890110188223.<\/b><\/p>\n

Graxostat 40mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n

Th\u00e0nh ph\u1ea7n<\/h3>\n

Vi\u00ean u\u1ed1ng Graxostat 40mg <\/b>g\u1ed3m c\u00e1c th\u00e0nh ph\u1ea7n sau:<\/p>\n\n\n\n\n\n
Th\u00e0nh ph\u1ea7n<\/td>\nH\u00e0m l\u01b0\u1ee3ng<\/td>\n<\/tr>\n
Febuxostat<\/td>\n40mg<\/td>\n<\/tr>\n
T\u00e1 d\u01b0\u1ee3c<\/td>\nV\u1eeba \u0111\u1ee7<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim.<\/p>\n

Tr\u00ecnh b\u00e0y<\/h3>\n

S\u0110K: 890110188223.<\/p>\n

Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean.<\/p>\n

Xu\u1ea5t x\u1ee9: \u1ea4n \u0110\u1ed9.<\/p>\n

T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Graxostat 40mg<\/h2>\n

C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n

Acid uric l\u00e0 s\u1ea3n ph\u1ea9m cu\u1ed1i c\u00f9ng trong qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a purin \u1edf con ng\u01b0\u1eddi, n\u00f3 \u0111\u01b0\u1ee3c t\u1ea1o ra d\u1ef1a v\u00e0o 2 giai \u0111o\u1ea1n v\u00e0 c\u00e1c giai \u0111o\u1ea1n \u0111\u1ec1u do xanthin oxidase (XO) x\u00fac t\u00e1c. M\u1ed9t lo\u1ea1i d\u1eabn xu\u1ea5t c\u1ee7a 2-arythiazon v\u1edbi t\u00ean g\u1ecdi Febuxostat c\u00f3 hi\u1ec7u qu\u1ea3 t\u1ed1t trong l\u00e0m gi\u1ea3m l\u01b0\u1ee3ng acid uric trong huy\u1ebft t\u01b0\u01a1ng, t\u00e1c \u0111\u1ed9ng n\u00e0y nh\u1edd kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf c\u00f3 ch\u1ecdn l\u1ecdc c\u1ee7a thu\u1ed1c tr\u00ean XO.<\/p>\n

V\u1edbi li\u1ec1u \u0111i\u1ec1u tr\u1ecb, Febuxostat kh\u00f4ng c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf nh\u1eefng men chuy\u1ec3n h\u00f3a pyrimidin hay purin.<\/p>\n

D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n

H\u1ea5p thu: S\u1ef1 h\u1ea5p thu Febuxostat c\u1ee7a c\u01a1 th\u1ec3 di\u1ec5n ra nhanh v\u00e0 m\u1ea1nh, gi\u00e1 tr\u1ecb tmax c\u00f3 sau 1 t\u1edbi 1,5 ti\u1ebfng, sinh kh\u1ea3 d\u1ee5ng kho\u1ea3ng 84%.<\/p>\n

Ph\u00e2n b\u1ed1: Vd c\u1ee7a Febuxostat khi d\u00f9ng \u1edf kho\u1ea3ng li\u1ec1u 10-300mg \u0111\u01b0\u1eddng u\u1ed1ng \u0111\u1ea1t t\u1eeb 29 t\u1edbi 75 l\u00edt. L\u00ean \u0111\u1ebfn 99,2% thu\u1ed1c g\u1eafn v\u1edbi protein \u1edf huy\u1ebft t\u01b0\u01a1ng, trong \u0111\u00f3 ch\u1ee7 y\u1ebfu l\u00e0 albumin.<\/p>\n

Chuy\u1ec3n h\u00f3a: S\u1ef1 chuy\u1ec3n h\u00f3a c\u1ee7a Febuxostat l\u00e0 qu\u00e1 tr\u00ecnh li\u00ean h\u1ee3p th\u00f4ng qua UDPGT ho\u1eb7c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a do CYP450 x\u00fac t\u00e1c. \u0110\u00e3 x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c 4 ch\u1ea5t chuy\u1ec3n h\u00f3a hydroxyl, trong \u0111\u00f3 c\u00f3 2 ch\u1ea5t hi\u1ec7n di\u1ec7n \u1edf huy\u1ebft t\u01b0\u01a1ng c\u1ee7a ng\u01b0\u1eddi.<\/p>\n

Th\u1ea3i tr\u1eeb: Th\u1ea3i tr\u1eeb c\u1ee7a Febuxostat di\u1ec5n ra \u1edf c\u1ea3 th\u1eadn l\u1eabn gan. Sau khi u\u1ed1ng 80mg thu\u1ed1c, c\u00f3 t\u1edbi 49% li\u1ec1u xu\u1ea5t hi\u1ec7n \u1edf n\u01b0\u1edbc ti\u1ec3u, 45% thu\u1ed1c th\u1ea5y trong ph\u00e2n. Th\u1eddi gian b\u00e1n h\u1ee7y trong kho\u1ea3ng 5 t\u1edbi 8 ti\u1ebfng.<\/p>\n

Thu\u1ed1c Graxostat 40mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n

Thu\u1ed1c Graxostat 40mg \u0111\u01b0\u1ee3c d\u00f9ng nh\u1eb1m ch\u1eefa tr\u1ecb t\u00ecnh tr\u1ea1ng t\u0103ng acid uric huy\u1ebft tr\u00ean c\u00e1c b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh g\u00fat m\u1ea1n t\u00ednh.<\/p>\n

\"Thu\u1ed1c
Thu\u1ed1c Graxostat 40mg \u0111i\u1ec1u tr\u1ecb t\u0103ng acid uric huy\u1ebft tr\u00ean c\u00e1c b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh g\u00fat m\u1ea1n t\u00ednh<\/figcaption><\/figure>\n

C\u00e1ch d\u00f9ng v\u00e0 li\u1ec1u d\u00f9ng thu\u1ed1c Graxostat 40mg<\/h2>\n

Li\u1ec1u d\u00f9ng<\/h3>\n

Ng\u01b0\u1eddi l\u1edbn: Khuy\u1ebfn c\u00e1o d\u00f9ng kh\u1edfi \u0111\u1ea7u b\u1eb1ng 1 vi\u00ean Graxostat 40mg m\u1ed7i ng\u00e0y. Sau 2 tu\u1ea7n ch\u1eefa tr\u1ecb v\u1edbi li\u1ec1u 40mg\/ng\u00e0y, v\u1edbi nh\u1eefng ng\u01b0\u1eddi m\u00e0 ch\u01b0a c\u00f3 \u0111\u01b0\u1ee3c ch\u1ec9 s\u1ed1 acid uric huy\u1ebft d\u01b0\u1edbi 6mg\/dl th\u00ec n\u00ean u\u1ed1ng 2 vi\u00ean Graxostat 40mg\/l\u1ea7n\/ng\u00e0y.<\/p>\n

Ng\u01b0\u1eddi cao tu\u1ed5i d\u00f9ng gi\u1ed1ng ng\u01b0\u1eddi l\u1edbn.<\/p>\n

Ng\u01b0\u1eddi suy th\u1eadn, gan: B\u1ecb suy th\u1eadn v\u00e0 gan m\u1ee9c \u0111\u1ed9 nh\u1eb9 t\u1edbi v\u1eeba th\u00ec d\u00f9ng b\u00ecnh th\u01b0\u1eddng. Ch\u01b0a r\u00f5 an to\u00e0n, hi\u1ec7u qu\u1ea3 c\u1ee7a Febuxostat tr\u00ean c\u00e1c tr\u01b0\u1eddng h\u1ee3p b\u1ecb suy gan v\u00e0 th\u1eadn n\u1eb7ng.<\/p>\n

C\u00e1ch d\u00f9ng<\/h3>\n

Thu\u1ed1c Graxostat 40mg d\u00f9ng ngo\u00e0i hay trong b\u1eefa \u0103n theo \u0111\u01b0\u1eddng u\u1ed1ng.<\/p>\n

Kh\u00f4ng s\u1eed d\u1ee5ng Graxostat 40mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n

Ng\u01b0\u1eddi m\u1eabn c\u1ea3m v\u1edbi Febuxostat hay t\u00e1 d\u01b0\u1ee3c c\u1ee7a thu\u1ed1c Graxostat 40mg.<\/p>\n

Ng\u01b0\u1eddi b\u1ec7nh \u0111ang ph\u1ea3i \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Mercaptopurrin hay Azathioprin.<\/p>\n

L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Graxostat 40mg<\/h2>\n

Th\u1eadn tr\u1ecdng<\/h3>\n

Tr\u00e1nh d\u00f9ng Febuxostat \u0111\u1edbi v\u1edbi ng\u01b0\u1eddi \u0111ang thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9 ho\u1eb7c b\u1ec7nh l\u00fd suy tim sung huy\u1ebft.<\/p>\n

C\u00e1c ph\u1ea3n \u1ee9ng n\u1eb7ng nh\u01b0 h\u1ed9i ch\u1ee9ng SJS,…hi\u1ebfm x\u1ea3y ra. C\u1ea7n th\u00f4ng b\u00e1o t\u1edbi ng\u01b0\u1eddi b\u1ec7nh c\u00e1c d\u1ea5u hi\u1ec7u c\u1ee7a ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng v\u00e0 c\u1ea7n d\u1eebng thu\u1ed1c ngay khi c\u00f3 c\u00e1c d\u1ea5u hi\u1ec7u n\u00e0y.<\/p>\n

Kh\u00f4ng n\u00ean b\u1eaft \u0111\u1ea7u d\u00f9ng Febuxostat n\u1ebfu \u0111ang x\u1ea3y ra c\u01a1n g\u00fat c\u1ea5p, ch\u1ec9 n\u00ean d\u00f9ng khi c\u01a1n g\u00fat c\u1ea5p \u0111\u00e3 d\u1ecbu xu\u1ed1ng.<\/p>\n

Kh\u00f4ng n\u00ean d\u00f9ng Febuxostat cho nh\u1eefng ng\u01b0\u1eddi c\u00f3 urat h\u00ecnh th\u00e0nh nhanh ch\u00f3ng.<\/p>\n

Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng Graxostat 40mg v\u1edbi nh\u1eefng ng\u01b0\u1eddi gh\u00e9p t\u1ea1ng.<\/p>\n

N\u00ean \u0111\u00e1nh gi\u00e1 ch\u1ee9c n\u0103ng c\u1ee7a gan c\u1ea3 tr\u01b0\u1edbc v\u00e0 \u0111\u1ecbnh k\u1ef3 trong l\u00fac ch\u1eefa tr\u1ecb v\u1edbi Febuxostat.<\/p>\n

Th\u1eadn tr\u1ecdng khi d\u00f9ng Graxostat 40mg v\u1edbi ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng tuy\u1ebfn gi\u00e1p thay \u0111\u1ed5i.<\/p>\n

T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n

Th\u01b0\u1eddng g\u1eb7p nh\u01b0 nh\u1ee9c \u0111\u1ea7u, bu\u1ed3n \u00f3i, n\u1ed5i ban, c\u00f3 c\u01a1n g\u00fat c\u1ea5p t\u00ednh v\u00e0 ch\u1ee9c n\u0103ng gan b\u1ea5t th\u01b0\u1eddng.<\/p>\n

\u00cdt g\u1eb7p nh\u01b0 ng\u1ee9a, \u0111au b\u1ee5ng, t\u0103ng c\u00e2n, m\u1ea5t ng\u1ee7, gi\u1ea3m hemoglobin, s\u1ecfi m\u1eadt, proetin ni\u1ec7u, r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng d\u01b0\u01a1ng, t\u0103ng ch\u1ec9 s\u1ed1 creatinin, kali m\u00e1u,…<\/p>\n

Hi\u1ebfm g\u1eb7p: \u00d9 tai, h\u1ed9i ch\u1ee9ng SJS, ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7, v\u00e0ng da vi\u00eam gan, ti\u00eau c\u01a1 v\u00e2n, c\u1ee9ng c\u01a1, vi\u00eam th\u1eadn,…<\/p>\n

T\u01b0\u01a1ng t\u00e1c<\/h3>\n\n\n\n\n\n\n
Thu\u1ed1c<\/td>\nT\u01b0\u01a1ng t\u00e1c<\/td>\n<\/tr>\n
Mercaptopurrin hay Azathioprin<\/td>\nFebuxostat c\u00f3 th\u1ec3 khi\u1ebfn n\u1ed3ng \u0111\u1ed9 Mercaptopurrin hay Azathioprin \u1edf huy\u1ebft t\u01b0\u01a1ng t\u0103ng cao, b\u1edfi v\u1eady kh\u00f4ng \u0111\u01b0\u1ee3c ph\u1ed1i h\u1ee3p<\/td>\n<\/tr>\n
C\u00e1c thu\u1ed1c c\u1ea3m \u1ee9ng glucuronid h\u00f3a<\/td>\nC\u00f3 th\u1ec3 g\u00e2y t\u0103ng n\u1ed3ng \u0111\u1ed9, \u0111\u1ed3ng th\u1eddi g\u00e2y gi\u1ea3m hi\u1ec7u l\u1ef1c Febuxostat<\/td>\n<\/tr>\n
Thu\u1ed1c kh\u00e1ng acid<\/td>\nC\u00f3 th\u1ec3 l\u00e0m t\u1ed1c \u0111\u1ed9 h\u1ea5p thu Febuxostat ch\u1eadm h\u01a1n. Tuy nhi\u00ean v\u1eabn c\u00f3 th\u1ec3 d\u00f9ng \u0111\u1ed3ng th\u1eddi<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho m\u1eb9 mang thai v\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n

Kh\u00f4ng n\u00ean d\u00f9ng Graxostat 40mg tr\u00ean b\u00e0 m\u1eb9 c\u00f3 con b\u00fa ho\u1eb7c \u1edf thai k\u1ef3.<\/p>\n

L\u01b0u \u00fd s\u1eed d\u1ee5ng khi \u0111ang l\u00e1i xe, v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n

C\u1ea7n ph\u1ea3i c\u1ea9n tr\u1ecdng do thu\u1ed1c Graxostat 40mg c\u00f3 th\u1ec3 g\u00e2y m\u1edd m\u1eaft, bu\u1ed3n ng\u1ee7, d\u1ecb c\u1ea3m,…<\/p>\n

Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n

C\u1ea7n ti\u1ebfn h\u00e0nh theo d\u00f5i, h\u1ed7 tr\u1ee3 c\u0169ng nh\u01b0 \u0111i\u1ec1u tr\u1ecb c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a ng\u01b0\u1eddi qu\u00e1 li\u1ec1u thu\u1ed1c Febuxostat.<\/p>\n

Thu\u1ed1c Graxostat 40mg gi\u00e1 bao nhi\u00eau? mua \u1edf \u0111\u00e2u?<\/h2>\n

Thu\u1ed1c Graxostat 40mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Graxostat 40mg <\/b>c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadt t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n

Tr\u01b0\u1eddng h\u1ee3p Graxostat 40mg t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng v\u1edbi Graxostat 40mg nh\u01b0:<\/p>\n