{"id":109015,"date":"2025-01-23T13:50:54","date_gmt":"2025-01-23T06:50:54","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=109015"},"modified":"2025-07-24T13:22:40","modified_gmt":"2025-07-24T06:22:40","slug":"saditazo","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/saditazo\/","title":{"rendered":"Saditazo"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Saditazo \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Sakar Healthcare Pvt. Ltd, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-19526-15<\/strong><\/p>\n

Saditazo l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n
Th\u00e0nh ph\u1ea7n<\/h3>\n
Thu\u1ed1c Saditazo<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n
\n
Piperacillin (d\u01b0\u1edbi d\u1ea1ng piperacillin natri) 4g<\/li>\n
Tazobactam (d\u01b0\u1edbi d\u1ea1ng Tazobactam natri) 0,5g<\/li>\n
T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7<\/li>\n<\/ul>\n
D\u1ea1ng b\u00e0o ch\u1ebf: B\u1ed9t pha ti\u00eam<\/p>\n
Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: VN-19526-15<\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd b\u1ed9t pha ti\u00eam<\/p>\n
Xu\u1ea5t x\u1ee9: \u1ea4n \u0110\u1ed9<\/p>\n
T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Saditazo<\/h2>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n
Piperacillin:<\/p>\n
\n
\u1ee8c ch\u1ebf t\u1ed5ng h\u1ee3p th\u00e0nh t\u1ebf b\u00e0o vi khu\u1ea9n: Piperacillin ng\u0103n c\u1ea3n qu\u00e1 tr\u00ecnh x\u00e2y d\u1ef1ng th\u00e0nh t\u1ebf b\u00e0o m\u1edbi c\u1ee7a vi khu\u1ea9n, d\u1eabn \u0111\u1ebfn vi khu\u1ea9n b\u1ecb ph\u00e1 h\u1ee7y<\/li>\n
Ph\u1ed5 kh\u00e1ng khu\u1ea9n r\u1ed9ng: Thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng tr\u00ean nhi\u1ec1u lo\u1ea1i vi khu\u1ea9n, bao g\u1ed3m c\u1ea3 vi khu\u1ea9n Gram d\u01b0\u01a1ng v\u00e0 Gram \u00e2m<\/li>\n<\/ul>\n
Tazobactam:<\/p>\n
\n
\u1ee8c ch\u1ebf beta-lactamase: Tazobactam ng\u0103n ch\u1eb7n ho\u1ea1t \u0111\u1ed9ng c\u1ee7a c\u00e1c enzyme beta-lactamase do vi khu\u1ea9n ti\u1ebft ra, gi\u00fap b\u1ea3o v\u1ec7 piperacillin kh\u1ecfi b\u1ecb ph\u00e2n h\u1ee7y<\/li>\n
M\u1edf r\u1ed9ng ph\u1ed5 kh\u00e1ng khu\u1ea9n: Nh\u1edd t\u00e1c d\u1ee5ng c\u1ee7a tazobactam, ph\u1ed5 kh\u00e1ng khu\u1ea9n c\u1ee7a piperacilin \u0111\u01b0\u1ee3c m\u1edf r\u1ed9ng, bao g\u1ed3m c\u1ea3 c\u00e1c vi khu\u1ea9n kh\u00e1ng v\u1edbi c\u00e1c kh\u00e1ng sinh beta-lactam kh\u00e1c<\/li>\n<\/ul>\n
S\u1ef1 k\u1ebft h\u1ee3p gi\u1eefa Piperacillin v\u00e0 Tazobactam t\u1ea1o ra hi\u1ec7u qu\u1ea3 hi\u1ec7p \u0111\u1ed3ng, t\u0103ng c\u01b0\u1eddng kh\u1ea3 n\u0103ng di\u1ec7t khu\u1ea9n c\u0169ng nh\u01b0 kh\u1eafc ph\u1ee5c t\u00ecnh tr\u1ea1ng kh\u00e1ng thu\u1ed1c c\u1ee7a vi khu\u1ea9n, \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00e1c vi khu\u1ea9n s\u1ea3n sinh beta-lactamase.<\/p>\n
\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n\n\n\n\n\n\n\n\n\n\n\n
D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/strong><\/td>\n Piperacillin<\/strong><\/td>\n Tazobactam<\/strong><\/td>\n<\/tr>\n
H\u1ea5p thu<\/td>\n N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh \u0111\u1ea1t \u0111\u01b0\u1ee3c nhanh sau khi ti\u00eam truy\u1ec1n<\/td>\n<\/tr>\n
Ph\u00e2n b\u1ed1<\/td>\n R\u1ed9ng trong c\u00e1c m\u00f4 v\u00e0 d\u1ecbch c\u01a1 th\u1ec3<\/td>\n<\/tr>\n
Li\u00ean k\u1ebft protein<\/td>\n Kho\u1ea3ng 21%<\/td>\n Kho\u1ea3ng 23%<\/td>\n<\/tr>\n
Chuy\u1ec3n h\u00f3a<\/td>\n Th\u00e0nh desethyl piperacillin (\u00edt ho\u1ea1t t\u00ednh)<\/td>\n Th\u00e0nh ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh<\/td>\n<\/tr>\n
Th\u1ea3i tr\u1eeb<\/td>\n Ch\u1ee7 y\u1ebfu qua th\u1eadn d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i<\/td>\n Ch\u1ee7 y\u1ebfu qua th\u1eadn d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a<\/td>\n<\/tr>\n
Th\u1eddi gian b\u00e1n th\u1ea3i<\/td>\n Kho\u1ea3ng 0.7-1.2 gi\u1edd<\/td>\n<\/tr>\n
\u1ea2nh h\u01b0\u1edfng c\u1ee7a b\u1ec7nh l\u00fd<\/td>\n T\u0103ng th\u1eddi gian b\u00e1n th\u1ea3i \u1edf ng\u01b0\u1eddi suy th\u1eadn<\/td>\n<\/tr>\n
\u1ea2nh h\u01b0\u1edfng c\u1ee7a tu\u1ed5i<\/td>\n \u1ede tr\u1ebb s\u01a1 sinh, thanh th\u1ea3i ch\u1eadm h\u01a1n so v\u1edbi tr\u1ebb l\u1edbn<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Thu\u1ed1c Saditazo \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n
Thu\u1ed1c Saditazo<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb m\u1ed9t lo\u1ea1t c\u00e1c nhi\u1ec5m khu\u1ea9n do vi khu\u1ea9n g\u00e2y ra, bao g\u1ed3m nhi\u1ec5m khu\u1ea9n da v\u00e0 m\u00f4 m\u1ec1m, nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p d\u01b0\u1edbi, nhi\u1ec5m khu\u1ea9n huy\u1ebft, nhi\u1ec5m khu\u1ea9n \u1ed5 b\u1ee5ng, nhi\u1ec5m khu\u1ea9n s\u1ea3n ph\u1ee5 khoa, nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u, v\u00e0 nhi\u1ec5m tr\u00f9ng h\u1ed7n h\u1ee3p.<\/p>\n
Thu\u1ed1c Saditazo \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 th\u1ebf n\u00e0o?<\/h2>\n
Li\u1ec1u d\u00f9ng<\/h3>\n
Ng\u01b0\u1eddi l\u1edbn & tr\u1ebb t\u1eeb 12 tu\u1ed5i (ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng): 4,5g ng\u00e0y 3 l\u1ea7n<\/p>\n
B\u1ea1ch c\u1ea7u trung t\u00ednh gi\u1ea3m: 4,5g m\u1ed7i 6 gi\u1edd, k\u1ebft h\u1ee3p aminoglycoside<\/p>\n
T\u1ed5ng li\u1ec1u h\u00e0ng ng\u00e0y: 2,25g – 4,5g ng\u00e0y 3-4 l\u1ea7n<\/p>\n
Tr\u1ebb < 12 tu\u1ed5i: Ch\u1ec9 d\u00f9ng cho tr\u1ebb b\u1ecb gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh<\/p>\n
Tr\u1ebb > 50kg: D\u00f9ng theo li\u1ec1u ng\u01b0\u1eddi l\u1edbn (kh\u00f4ng k\u1ebft h\u1ee3p aminoglycoside)<\/p>\n
Tr\u1ebb < 30kg (ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng): 90mg\/kg (80mg piperacillin + 10mg tazobactam) m\u1ed7i 6 gi\u1edd, k\u1ebft h\u1ee3p aminoglycoside<\/p>\n
Tr\u1ebb < 2 th\u00e1ng tu\u1ed5i: Kh\u00f4ng khuy\u1ebfn ngh\u1ecb s\u1eed d\u1ee5ng<\/p>\n
Ng\u01b0\u1eddi cao tu\u1ed5i: D\u00f9ng theo li\u1ec1u ng\u01b0\u1eddi l\u1edbn, tr\u1eeb khi c\u00f3 suy th\u1eadn<\/p>\n
B\u1ea3ng \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u cho b\u1ec7nh nh\u00e2n suy th\u1eadn:<\/p>\n\n\n\n\n\n\n\n\n\n\n
\u0110\u1ed1i t\u01b0\u1ee3ng<\/td>\n CrCl (ml\/ph\u00fat)<\/td>\n Li\u1ec1u d\u00f9ng<\/td>\n<\/tr>\n
Ng\u01b0\u1eddi l\u1edbn & tr\u1ebb > 50kg<\/td>\n 20 – 80<\/td>\n 4g piperacillin + 0,5g tazobactam x 3 l\u1ea7n\/ng\u00e0y<\/td>\n<\/tr>\n
< 20<\/td>\n 4g piperacillin + 0,5g tazobactam x 2 l\u1ea7n\/ng\u00e0y<\/td>\n<\/tr>\n
Ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o<\/td>\n T\u1ed1i \u0111a 8g piperacillin + 1g tazobactam\/ng\u00e0y.B\u1ed5 sung 2g piperacillin + 0,25g tazobactam sau m\u1ed7i l\u1ea7n ch\u1ea1y th\u1eadn<\/td>\n<\/tr>\n
Tr\u1ebb < 50kg<\/td>\n 40 – 80<\/td>\n 90mg\/kg x 4 l\u1ea7n\/ng\u00e0y<\/td>\n<\/tr>\n
20 – 40<\/td>\n 90mg\/kg x 3 l\u1ea7n\/ng\u00e0y<\/td>\n<\/tr>\n
< 20<\/td>\n 90mg\/kg x 2 l\u1ea7n\/ng\u00e0y<\/td>\n<\/tr>\n
Ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o<\/td>\n 45mg\/kg (40mg piperacillin + 5mg tazobactam) x 3 l\u1ea7n\/ng\u00e0y<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb: D\u00f9ng \u00edt nh\u1ea5t 48 gi\u1edd sau khi h\u1ebft s\u1ed1t ho\u1eb7c c\u00e1c tri\u1ec7u ch\u1ee9ng nhi\u1ec5m tr\u00f9ng.<\/p>\n
C\u00e1ch d\u00f9ng<\/h3>\n
Pha ch\u1ebf: Pha m\u1ed7i l\u1ecd 4.5g thu\u1ed1c v\u1edbi 20ml dung d\u1ecbch NaCl 0.9% ho\u1eb7c n\u01b0\u1edbc c\u1ea5t v\u00f4 tr\u00f9ng.<\/p>\n
Ti\u00eam:<\/p>\n
\n
Ti\u00eam m\u1ea1ch ch\u1eadm: Pha m\u1ed7i l\u1ecd 4,5g v\u1edbi 20ml n\u01b0\u1edbc c\u1ea5t ho\u1eb7c NaCl 0,9%, ti\u00eam ch\u1eadm trong 3 – 5 ph\u00fat<\/li>\n
Truy\u1ec1n t\u0129nh m\u1ea1ch: Pha m\u1ed7i l\u1ecd 4,5g v\u1edbi 20ml n\u01b0\u1edbc c\u1ea5t ho\u1eb7c NaCl 0,9%, sau \u0111\u00f3 pha lo\u00e3ng th\u00e0nh \u00edt nh\u1ea5t 50ml v\u1edbi dung m\u00f4i t\u01b0\u01a1ng th\u00edch (Dextrose 5% + NaCl 0,9%; Dextrose 5%; NaCl 0,9%), truy\u1ec1n trong 20 – 30 ph\u00fat<\/li>\n<\/ul>\n
L\u01b0u \u00fd:<\/p>\n
\n
Kh\u00f4ng pha chung v\u1edbi thu\u1ed1c kh\u00e1c.<\/li>\n
Kh\u00f4ng pha v\u1edbi dung d\u1ecbch natri bicarbonat.<\/li>\n<\/ul>\n
Dung d\u1ecbch sau pha lo\u00e3ng:<\/p>\n
\n
\u1ed4n \u0111\u1ecbnh trong 12 gi\u1edd \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng<\/li>\n
B\u1ea3o qu\u1ea3n l\u1ea1nh (2 – 8\u00b0C) gi\u1eef \u0111\u01b0\u1ee3c 24 gi\u1edd<\/li>\n<\/ul>\n
$\"Thu\u1ed1c$
Thu\u1ed1c Saditazo ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh g\u00ec?<\/figcaption><\/figure>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Saditazo trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n
Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng thu\u1ed1c Saditazo:<\/p>\n
Ng\u01b0\u1eddi m\u1eabn c\u1ea3m v\u1edbi penicillin, cephalosporin ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c<\/p>\n
Tr\u1ebb s\u01a1 sinh d\u01b0\u1edbi 2 th\u00e1ng tu\u1ed5i<\/p>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Saditazo<\/h2>\n
Th\u1eadn tr\u1ecdng<\/h3>\n
Tr\u01b0\u1edbc khi d\u00f9ng, c\u1ea7n h\u1ecfi k\u1ef9 v\u1ec1 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi penicillin, cephalosporin ho\u1eb7c c\u00e1c d\u1ecb nguy\u00ean kh\u00e1c. N\u1ebfu c\u00f3 ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng, ph\u1ea3i ng\u1eebng thu\u1ed1c Saditazo ngay; tr\u01b0\u1eddng h\u1ee3p nghi\u00eam tr\u1ecdng c\u00f3 th\u1ec3 c\u1ea7n d\u00f9ng adrenalin v\u00e0 c\u00e1c bi\u1ec7n ph\u00e1p c\u1ea5p c\u1ee9u.<\/p>\n
D\u00f9 c\u00f3 \u0111\u1ed9c t\u00ednh th\u1ea5p nh\u01b0 c\u00e1c kh\u00e1ng sinh h\u1ecd penicillin, v\u1eabn c\u1ea7n ki\u1ec3m tra \u0111\u1ecbnh k\u1ef3 ch\u1ee9c n\u0103ng gan, th\u1eadn v\u00e0 h\u1ec7 t\u1ea1o m\u00e1u khi \u0111i\u1ec1u tr\u1ecb d\u00e0i ng\u00e0y. \u1ede b\u1ec7nh nh\u00e2n suy th\u1eadn ho\u1eb7c suy gan, n\u00ean \u0111o n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ec3 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u ph\u00f9 h\u1ee3p.<\/p>\n
Nguy c\u01a1 ch\u1ea3y m\u00e1u: M\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n d\u00f9ng kh\u00e1ng sinh beta-lactam c\u00f3 th\u1ec3 g\u1eb7p r\u1ed1i lo\u1ea1n \u0111\u00f4ng m\u00e1u, nh\u1ea5t l\u00e0 \u1edf ng\u01b0\u1eddi suy th\u1eadn. N\u1ebfu xu\u1ea5t huy\u1ebft x\u1ea3y ra do thu\u1ed1c, c\u1ea7n ng\u1eebng \u0111i\u1ec1u tr\u1ecb v\u00e0 c\u00f3 bi\u1ec7n ph\u00e1p x\u1eed l\u00fd th\u00edch h\u1ee3p.<\/p>\n
Khi s\u1eed d\u1ee5ng k\u00e9o d\u00e0i, c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n vi khu\u1ea9n kh\u00e1ng thu\u1ed1c. N\u1ebfu x\u1ea3y ra, c\u1ea7n thay \u0111\u1ed5i ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb.
\nKh\u00e1ng sinh, bao g\u1ed3m Piperacillin, c\u00f3 li\u00ean quan \u0111\u1ebfn vi\u00eam ru\u1ed9t k\u1ebft m\u00e0ng gi\u1ea3 do Clostridium difficile, c\u00f3 th\u1ec3 g\u00e2y ti\u00eau ch\u1ea3y t\u1eeb nh\u1eb9 \u0111\u1ebfn n\u1eb7ng, th\u1eadm ch\u00ed \u0111e d\u1ecda t\u00ednh m\u1ea1ng. Tr\u01b0\u1eddng h\u1ee3p nh\u1eb9 ch\u1ec9 c\u1ea7n ng\u1eebng thu\u1ed1c, nh\u01b0ng n\u1ebfu n\u1eb7ng, c\u1ea7n d\u00f9ng kh\u00e1ng sinh \u0111\u1eb7c hi\u1ec7u ch\u1ed1ng C. difficile.<\/p>\n
Gi\u1ed1ng c\u00e1c penicillin kh\u00e1c, li\u1ec1u cao qua \u0111\u01b0\u1eddng ti\u00eam t\u0129nh m\u1ea1ch c\u00f3 th\u1ec3 g\u00e2y k\u00edch \u0111\u1ed9ng th\u1ea7n kinh c\u01a1 ho\u1eb7c co gi\u1eadt.<\/p>\n
M\u1ed7i l\u1ecd 4,5g ch\u1ee9a 216mg natri, c\u00f3 th\u1ec3 l\u00e0m t\u0103ng h\u1ea5p thu natri. Do \u0111\u00f3, c\u1ea7n ki\u1ec3m so\u00e1t l\u01b0\u1ee3ng mu\u1ed1i trong ch\u1ebf \u0111\u1ed9 \u0103n, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n h\u1ea1n ch\u1ebf mu\u1ed1i.<\/p>\n
N\u00ean theo d\u00f5i ion \u0111\u1ed3 \u0111\u1ecbnh k\u1ef3 \u1edf b\u1ec7nh nh\u00e2n c\u00f3 d\u1ef1 tr\u1eef kali th\u1ea5p, nh\u1eefng ng\u01b0\u1eddi \u0111ang d\u00f9ng thu\u1ed1c l\u1ee3i ti\u1ec3u ho\u1eb7c h\u00f3a tr\u1ecb.<\/p>\n
\u1ea2nh h\u01b0\u1edfng ch\u1ee9c n\u0103ng gan: C\u00f3 th\u1ec3 l\u00e0m t\u0103ng nh\u1eb9 ch\u1ec9 s\u1ed1 ch\u1ee9c n\u0103ng gan.<\/p>\n
\u1ea2nh h\u01b0\u1edfng \u0111\u1ebfn ch\u1ea9n \u0111o\u00e1n giang mai: Li\u1ec1u cao ng\u1eafn ng\u00e0y \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb l\u1eadu c\u00f3 th\u1ec3 che gi\u1ea5u ho\u1eb7c l\u00e0m ch\u1eadm bi\u1ec3u hi\u1ec7n giang mai. V\u00ec v\u1eady, c\u1ea7n x\u00e9t nghi\u1ec7m giang mai tr\u01b0\u1edbc khi \u0111i\u1ec1u tr\u1ecb v\u00e0 theo d\u00f5i huy\u1ebft thanh \u00edt nh\u1ea5t 4 th\u00e1ng sau \u0111\u00f3.<\/p>\n
Gi\u1ea3m b\u1ea1ch c\u1ea7u: C\u00f3 th\u1ec3 x\u1ea3y ra, \u0111\u1eb7c bi\u1ec7t khi d\u00f9ng thu\u1ed1c k\u00e9o d\u00e0i, n\u00ean c\u1ea7n ki\u1ec3m tra c\u00f4ng th\u1ee9c m\u00e1u \u0111\u1ecbnh k\u1ef3.<\/p>\n
Hi\u1ec7n ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u \u0111\u00e1nh gi\u00e1 t\u00e1c \u0111\u1ed9ng c\u1ee7a thu\u1ed1c \u0111\u1ebfn vi\u1ec7c l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n
T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/h3>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
C\u01a1 quan<\/td>\n Th\u01b0\u1eddng g\u1eb7p<\/td>\n \u00cdt g\u1eb7p<\/td>\n Hi\u1ebfm g\u1eb7p<\/td>\n<\/tr>\n
Chuy\u1ec3n h\u00f3a<\/td>\n <\/td>\n Vi\u00eam khi gi\u1ea3m albumin huy\u1ebft, glucose m\u00e1u v\u00e0 protein m\u00e1u<\/td>\n Gi\u1ea3m kali huy\u1ebft<\/td>\n<\/tr>\n
C\u01a1 x\u01b0\u01a1ng<\/td>\n Vi\u00eam kh\u1edbp, \u0111au m\u1ecfi c\u01a1, gi\u00e3n c\u01a1 k\u00e9o d\u00e0i<\/td>\n <\/td>\n <\/td>\n<\/tr>\n
Da<\/td>\n M\u1ea9n ng\u1ee9a, ban \u0111\u1ecf, ng\u1ee9a, ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng, v\u00e3 ti\u1ebft m\u1ed3 h\u00f4i<\/td>\n Ban \u0111\u1ecf \u0111a h\u00ecnh, ch\u00e0m, d\u00e1t s\u1ea7n, ngo\u1ea1i ban<\/td>\n H\u1ed9i ch\u1ee9ng ho\u1ea1i t\u1eed th\u01b0\u1ee3ng b\u00ec nhi\u1ec5m \u0111\u1ed9c<\/td>\n<\/tr>\n
Gan<\/td>\n T\u0103ng men gan, bilirubin trong huy\u1ebft thanh<\/td>\n <\/td>\n <\/td>\n<\/tr>\n
Huy\u1ebft h\u1ecdc<\/td>\n Gi\u1ea3m t\u1ea1m th\u1eddi s\u1ed1 l\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u, b\u1ea1ch c\u1ea7u \u01b0a axit t\u0103ng, gi\u1ea3m\/t\u0103ng s\u1ed1 l\u01b0\u1ee3ng ti\u1ec3u c\u1ea7u<\/td>\n Test Coombs (+)<\/td>\n <\/td>\n<\/tr>\n
M\u1ea1ch<\/td>\n Vi\u00eam t\u0129nh m\u1ea1ch n\u00f4ng, h\u1ea1 huy\u1ebft \u00e1p, huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u<\/td>\n <\/td>\n <\/td>\n<\/tr>\n
Mi\u1ec5n d\u1ecbch<\/td>\n Qu\u00e1 m\u1eabn<\/td>\n <\/td>\n S\u1ed1c<\/td>\n<\/tr>\n
Ph\u1ee5 khoa<\/td>\n <\/td>\n Nhi\u1ec5m n\u1ea5m Candida (\u0111\u1eb7c bi\u1ec7t khi \u0111i\u1ec1u tr\u1ecb d\u00e0i ng\u00e0y)<\/td>\n <\/td>\n<\/tr>\n
T\u1ea1i ch\u1ed7<\/td>\n \u0110au, vi\u00eam t\u1ea1i ch\u1ed7 ti\u00eam<\/td>\n <\/td>\n <\/td>\n<\/tr>\n
Th\u1eadn<\/td>\n R\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng th\u1eadn<\/td>\n Vi\u00eam th\u1eadn k\u1ebd, suy th\u1eadn<\/td>\n <\/td>\n<\/tr>\n
Th\u1ea7n kinh<\/td>\n Y\u1ebfu c\u01a1, \u1ea3o gi\u00e1c, nh\u1ee9c \u0111\u1ea7u, m\u1ea5t ng\u1ee7, suy nh\u01b0\u1ee3c, ch\u00f3ng m\u1eb7t<\/td>\n <\/td>\n <\/td>\n<\/tr>\n
Ti\u00eau h\u00f3a<\/td>\n \u0110i ngo\u00e0i ph\u00e2n l\u1ecfng, mu\u1ed1n n\u00f4n, tr\u1edb, m\u1ec1 \u0111ay<\/td>\n Vi\u00eam ni\u00eam m\u1ea1c mi\u1ec7ng, kh\u00f3 \u0111\u1ea1i ti\u1ec7n, \u0111\u1ea7y b\u1ee5ng, \u0111i ngo\u00e0i ra m\u00e1u, \u0111au b\u1ee5ng<\/td>\n Vi\u00eam m\u00e0ng gi\u1ea3<\/td>\n<\/tr>\n
To\u00e0n th\u00e2n<\/td>\n T\u0103ng t\u1ef7 l\u1ec7 s\u1ed1t, m\u1ea9n ng\u1ee9a<\/td>\n <\/td>\n <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h3>\n\n\n\n\n\n\n\n\n\n\n
Thu\u1ed1c k\u1ebft h\u1ee3p<\/td>\n T\u01b0\u01a1ng t\u00e1c<\/td>\n<\/tr>\n
Vecuronium<\/td>\n K\u00e9o d\u00e0i th\u1eddi gian t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c gi\u00e3n c\u01a1<\/td>\n<\/tr>\n
Vancomycin<\/td>\n Kh\u00f4ng c\u00f3 t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc \u0111\u00e1ng k\u1ec3<\/td>\n<\/tr>\n
Probenecid<\/td>\n T\u0103ng th\u1eddi gian b\u00e1n h\u1ee7y v\u00e0 t\u1ed1c \u0111\u1ed9 thanh th\u1ea3i c\u1ee7a Piperacillin v\u00e0 Tazobactam, kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh<\/td>\n<\/tr>\n
Methotrexate<\/td>\n Gi\u1ea3m thanh th\u1ea3i methotrexate, t\u0103ng nguy c\u01a1 \u0111\u1ed9c t\u00ednh<\/td>\n<\/tr>\n
Heparin v\u00e0 thu\u1ed1c kh\u00e1ng \u0111\u00f4ng \u0111\u01b0\u1eddng u\u1ed1ng<\/td>\n T\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u, c\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd th\u00f4ng s\u1ed1 \u0111\u00f4ng m\u00e1u<\/td>\n<\/tr>\n
C\u00e1c thu\u1ed1c kh\u00e1c<\/td>\n C\u00f3 th\u1ec3 g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m glucose ni\u1ec7u<\/td>\n<\/tr>\n
Aminoglycoside (v\u00ed d\u1ee5: Tobramycin)<\/td>\n C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1eeda \u0111\u1eddi th\u1ea3i tr\u1eeb v\u00e0 t\u0103ng thanh th\u1ea3i to\u00e0n ph\u1ea7n c\u1ee7a aminoglycosid \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn n\u1eb7ng<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/h3>\n
Ph\u1ee5 n\u1eef mang thai: Do ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u v\u1ec1 t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c \u0111\u1ed1i v\u1edbi thai nhi, ch\u1ec9 n\u00ean s\u1eed d\u1ee5ng Piperacillin\/Tazobactam khi th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft v\u00e0 d\u01b0\u1edbi s\u1ef1 c\u00e2n nh\u1eafc k\u1ef9 l\u01b0\u1ee1ng c\u1ee7a b\u00e1c s\u0129.<\/p>\n
Ph\u1ee5 n\u1eef cho con b\u00fa: M\u1ed9t l\u01b0\u1ee3ng nh\u1ecf thu\u1ed1c c\u00f3 th\u1ec3 \u0111i v\u00e0o s\u1eefa m\u1eb9. \u0110\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n cho tr\u1ebb, n\u00ean ng\u1eebng cho con b\u00fa trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Piperacillin\/Tazobactam.<\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n
Khi d\u00f9ng qu\u00e1 li\u1ec1u Piperacillin\/Tazobactam, b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 g\u1eb7p c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0:<\/p>\n
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Ti\u00eau h\u00f3a: Bu\u1ed3n n\u00f4n, n\u00f4n, ti\u00eau ch\u1ea3y<\/li>\n
Th\u1ea7n kinh: Co gi\u1eadt, k\u00edch th\u00edch th\u1ea7n kinh c\u01a1 (\u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn suy gi\u1ea3m)<\/li>\n<\/ul>\n
X\u1eed tr\u00ed:<\/p>\n
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N\u1ebfu b\u1ec7nh nh\u00e2n u\u1ed1ng qu\u00e1 li\u1ec1u, c\u00f3 th\u1ec3 th\u1ef1c hi\u1ec7n r\u1eeda d\u1ea1 d\u00e0y<\/li>\n
Th\u1ea9m t\u00e1ch m\u00e1u trong tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u n\u1eb7ng<\/li>\n
\u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng:\n
\n
K\u00edch \u0111\u1ed9ng th\u1ea7n kinh c\u01a1, co gi\u1eadt: S\u1eed d\u1ee5ng thu\u1ed1c ch\u1ed1ng co gi\u1eadt<\/li>\n
Ti\u00eau ch\u1ea3y n\u1eb7ng: Ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c, \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng kh\u00e1ng sinh kh\u00e1c<\/li>\n
C\u1ea5p c\u1ee9u theo ph\u00e1c \u0111\u1ed3 s\u1ed1c ph\u1ea3n v\u1ec7<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n
Thu\u1ed1c Saditazo gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n
Thu\u1ed1c Saditazo hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n
Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Saditazo t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Saditazo nh\u01b0:<\/p>\n
Thu\u1ed1c Zavicefta 2g\/0,5g<\/a> do ACS Dobfar S.P.A s\u1ea3n xu\u1ea5t v\u1edbi gi\u00e1 29.100.000\u0111\/h\u1ed9p, ch\u1ee9a Ceftazidime 2g v\u00e0 Avibactam 0,5g, c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u00e1c nhi\u1ec5m tr\u00f9ng trong \u1ed5 b\u1ee5ng, nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u, vi\u00eam ph\u1ed5i m\u1eafc ph\u1ea3i t\u1ea1i b\u1ec7nh vi\u1ec7n v\u00e0 nhi\u1ec5m tr\u00f9ng do vi khu\u1ea9n Gram \u00e2m hi\u1ebfu kh\u00ed, ch\u1ec9 \u0111\u1ecbnh cho ng\u01b0\u1eddi l\u1edbn b\u1ecb nhi\u1ec5m tr\u00f9ng ph\u1ee9c t\u1ea1p v\u00e0 kh\u00e1ng thu\u1ed1c.<\/p>\n
Thu\u1ed1c Unasyn 1,5g<\/a> do Haupt Pharma Latina S.r.l \u2013 Italy s\u1ea3n xu\u1ea5t v\u1edbi gi\u00e1 150.000\u0111\/h\u1ed9p, ch\u1ee9a Sulbactam 0,5g v\u00e0 Ampicillin 1g, c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u00e1c nhi\u1ec5m khu\u1ea9n h\u00f4 h\u1ea5p, huy\u1ebft, da, ti\u1ebft ni\u1ec7u, \u1ed5 b\u1ee5ng, x\u01b0\u01a1ng kh\u1edbp, l\u1eadu c\u1ea7u, v\u00e0 d\u1ef1 ph\u00f2ng nhi\u1ec5m khu\u1ea9n sau ph\u1eabu thu\u1eadt \u1edf b\u1ec7nh nh\u00e2n m\u1eafc khu\u1ea9n nh\u1ea1y c\u1ea3m.<\/p>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n
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Alfred Gin, Leanne Dilay, James A Karlowsky, Andrew Walkty, Ethan Rubinstein, George G Zhanel. (Th\u00e1ng 6 n\u0103m 2007). Piperacillin-tazobactam: a beta-lactam\/beta-lactamase inhibitor combination.<\/em> Truy c\u1eadp ng\u00e0y 23 th\u00e1ng 1 n\u0103m 2025, t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/17547502\/<\/a><\/li>\n
Kohei Takimoto, Qianzhi Wang, Daisuke Suzuki, Mitsuya Katayama, Yoshiro Hayashi. (Ng\u00e0y 23 th\u00e1ng 6 n\u0103m 2017). Clinical efficacy of piperacillin\/tazobactam in the treatment of complicated skin and soft tissue infections<\/em>. Truy c\u1eadp ng\u00e0y 23 th\u00e1ng 1 n\u0103m 2025, t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/28627952\/\u00a0<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"
Thu\u1ed1c Saditazo \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb m\u1ed9t lo\u1ea1t c\u00e1c nhi\u1ec5m khu\u1ea9n do vi khu\u1ea9n g\u00e2y ra, bao g\u1ed3m nhi\u1ec5m khu\u1ea9n da v\u00e0 m\u00f4 m\u1ec1m, nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p d\u01b0\u1edbi, nhi\u1ec5m khu\u1ea9n huy\u1ebft, nhi\u1ec5m khu\u1ea9n \u1ed5 b\u1ee5ng, nhi\u1ec5m khu\u1ea9n s\u1ea3n ph\u1ee5 khoa, nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u, v\u00e0 nhi\u1ec5m tr\u00f9ng h\u1ed7n h\u1ee3p<\/span><\/p>\n","protected":false},"author":1,"featured_media":109016,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-109015","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/109015","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=109015"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/109016"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=109015"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=109015"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=109015"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

Tr\u00ecnh b\u00e0y<\/h3>\nS\u0110K: VN-19526-15<\/p>\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd b\u1ed9t pha ti\u00eam<\/p>\nXu\u1ea5t x\u1ee9: \u1ea4n \u0110\u1ed9<\/p>\n

T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Saditazo<\/h2>\n

L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Saditazo<\/h2>\n

Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: VN-19526-15<\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd b\u1ed9t pha ti\u00eam<\/p>\n
Xu\u1ea5t x\u1ee9: \u1ea4n \u0110\u1ed9<\/p>\n