{"id":108454,"date":"2025-01-11T13:48:30","date_gmt":"2025-01-11T06:48:30","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=108454"},"modified":"2025-07-24T13:22:43","modified_gmt":"2025-07-24T06:22:43","slug":"pizulen-1g","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/pizulen-1g\/","title":{"rendered":"Pizulen 1g"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m <a href=\"https:\/\/vnras.com\/drug\/pizulen-1g\/\">thu\u1ed1c Pizulen 1g<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Demo S.A. Pharmaceutical Industry, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 520110071823<\/strong><\/p>\n<h2>Pizulen 1g l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Thu\u1ed1c Pizulen 1g<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li>Meropenem (d\u01b0\u1edbi d\u1ea1ng Meropenem trihydrat) 1000mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Thu\u1ed1c b\u1ed9t pha ti\u00eam ho\u1eb7c ti\u00eam truy\u1ec1n<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 520110071823<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd, H\u1ed9p 10 l\u1ecd, H\u1ed9p 50 l\u1ecd.<\/p>\n<p>Xu\u1ea5t x\u1ee9: Hy L\u1ea1p<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Pizulen 1g<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p><strong>Meropenem<\/strong> l\u00e0 m\u1ed9t kh\u00e1ng sinh carbapenem, c\u00f3 c\u1ea5u tr\u00fac b\u1ec1n v\u1eefng, kh\u00f3 b\u1ecb c\u00e1c enzyme c\u1ee7a vi khu\u1ea9n ph\u00e2n h\u1ee7y.<\/p>\n<p>Thu\u1ed1c g\u1eafn k\u1ebft v\u1edbi c\u00e1c protein li\u00ean k\u1ebft penicillin (PBPs) tr\u00ean th\u00e0nh t\u1ebf b\u00e0o vi khu\u1ea9n, \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p peptidoglycan &#8211; th\u00e0nh ph\u1ea7n ch\u00ednh c\u1ee7a v\u00e1ch t\u1ebf b\u00e0o vi khu\u1ea9n.<\/p>\n<p>Nh\u1edd c\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng n\u00e0y, Meropenem c\u00f3 kh\u1ea3 n\u0103ng ti\u00eau di\u1ec7t nhi\u1ec1u lo\u1ea1i vi khu\u1ea9n g\u00e2y b\u1ec7nh, k\u1ec3 c\u1ea3 nh\u1eefng vi khu\u1ea9n \u0111\u00e3 kh\u00e1ng thu\u1ed1c v\u1edbi c\u00e1c lo\u1ea1i kh\u00e1ng sinh kh\u00e1c.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu v\u00e0 ph\u00e2n b\u1ed1<\/p>\n<ul>\n<li>H\u1ea5p thu: Khi ti\u00eam t\u0129nh m\u1ea1ch, Meropenem \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng nhanh ch\u00f3ng, th\u01b0\u1eddng trong v\u00f2ng 5 ph\u00fat. N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec1u d\u00f9ng.<\/li>\n<li>Ph\u00e2n b\u1ed1: Meropenem ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i \u0111\u1ebfn h\u1ea7u h\u1ebft c\u00e1c m\u00f4 v\u00e0 d\u1ecbch c\u01a1 th\u1ec3, bao g\u1ed3m c\u1ea3 d\u1ecbch n\u00e3o t\u1ee7y, \u0111\u1eb7c bi\u1ec7t h\u1eefu \u00edch trong \u0111i\u1ec1u tr\u1ecb c\u00e1c nhi\u1ec5m khu\u1ea9n h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng.<\/li>\n<\/ul>\n<p>Chuy\u1ec3n h\u00f3a v\u00e0 th\u1ea3i tr\u1eeb<\/p>\n<ul>\n<li>Chuy\u1ec3n h\u00f3a: Meropenem ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i qua th\u1eadn.<\/li>\n<li>Th\u1ea3i tr\u1eeb: Kho\u1ea3ng 70% li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua n\u01b0\u1edbc ti\u1ec3u trong v\u00f2ng 12 gi\u1edd \u0111\u1ea7u.<\/li>\n<li>Th\u1eddi gian b\u00e1n th\u1ea3i: Kho\u1ea3ng 1-2 gi\u1edd \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh kh\u1ecfe m\u1ea1nh v\u00e0 c\u00f3 th\u1ec3 k\u00e9o d\u00e0i \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn.<\/li>\n<\/ul>\n<p>\u1ea2nh h\u01b0\u1edfng c\u1ee7a c\u00e1c y\u1ebfu t\u1ed1 \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/p>\n<ul>\n<li>Li\u1ec1u d\u00f9ng: N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng t\u1ef7 l\u1ec7 thu\u1eadn v\u1edbi li\u1ec1u d\u00f9ng<\/li>\n<li>Ch\u1ee9c n\u0103ng th\u1eadn: \u0110\u1ed9 thanh th\u1ea3i c\u1ee7a Meropenem gi\u1ea3m \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn, c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u<\/li>\n<li>Tu\u1ed5i: \u0110\u1ed9 thanh th\u1ea3i c\u1ee7a Meropenem gi\u1ea3m nh\u1eb9 \u1edf ng\u01b0\u1eddi cao tu\u1ed5i<\/li>\n<li>B\u1ec7nh gan kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a Meropenem<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Pizulen 1g \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p><strong>Thu\u1ed1c ti\u00eam truy\u1ec1n Pizulen 1g<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh nhi\u1ec5m tr\u00f9ng sau:<\/p>\n<ul>\n<li>Nhi\u1ec5m khu\u1ea9n n\u1eb7ng:\n<ul>\n<li>Nhi\u1ec5m khu\u1ea9n da v\u00e0 m\u00f4 m\u1ec1m<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u (c\u00f3 bi\u1ebfn ch\u1ee9ng ho\u1eb7c kh\u00f4ng bi\u1ebfn ch\u1ee9ng)<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n huy\u1ebft<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n \u1ed5 b\u1ee5ng<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n ph\u1ee5 khoa (vi\u00eam m\u00e0ng trong d\u1ea1 con, vi\u00eam v\u00f9ng ch\u1eadu)<\/li>\n<li>Vi\u00eam m\u00e0ng n\u00e3o<\/li>\n<li>Vi\u00eam ph\u1ed5i (kh\u00e1ng thu\u1ed1c, b\u1ec7nh vi\u1ec7n, do suy gi\u1ea3m mi\u1ec5n d\u1ecbch)<\/li>\n<\/ul>\n<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n \u0111\u1eb7c bi\u1ec7t:\n<ul>\n<li>Nhi\u1ec5m khu\u1ea9n \u1edf b\u1ec7nh nh\u00e2n x\u01a1 nang<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p d\u01b0\u1edbi m\u1ea1n t\u00ednh<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n h\u1ed7n h\u1ee3p<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Pizulen 1g<\/h2>\n<p>Li\u1ec1u d\u00f9ng c\u00f3 th\u1ec3 thay \u0111\u1ed5i t\u00f9y thu\u1ed9c v\u00e0o:<\/p>\n<ul>\n<li>\u0110\u1ed9 tu\u1ed5i c\u1ee7a b\u1ec7nh nh\u00e2n<\/li>\n<li>M\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a nhi\u1ec5m khu\u1ea9n<\/li>\n<li>Ch\u1ee9c n\u0103ng th\u1eadn v\u00e0 gan<\/li>\n<li>\u0110\u1ed9 nh\u1ea1y c\u1ea3m c\u1ee7a vi khu\u1ea9n<\/li>\n<\/ul>\n<p>Ng\u01b0\u1eddi l\u1edbn:<\/p>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 55.288%;\">Lo\u1ea1i nhi\u1ec5m khu\u1ea9n<\/td>\n<td style=\"width: 23.8431%;\">Li\u1ec1u d\u00f9ng (g)<\/td>\n<td style=\"width: 20.8688%;\">T\u1ea7n su\u1ea5t<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 55.288%;\">Vi\u00eam ph\u1ed5i, nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u, nhi\u1ec5m khu\u1ea9n ph\u1ee5 khoa, nhi\u1ec5m tr\u00f9ng da<\/td>\n<td style=\"width: 23.8431%;\">0,5<\/td>\n<td style=\"width: 20.8688%;\" rowspan=\"3\">3 l\u1ea7n\/ng\u00e0y<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 55.288%;\">Vi\u00eam ph\u1ed5i b\u1ec7nh vi\u1ec7n, vi\u00eam ph\u00fac m\u1ea1c, nhi\u1ec5m khu\u1ea9n huy\u1ebft, nhi\u1ec5m khu\u1ea9n \u1edf b\u1ec7nh nh\u00e2n gi\u1ea3m b\u1ea1ch c\u1ea7u<\/td>\n<td style=\"width: 23.8431%;\">1<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 55.288%;\">Vi\u00eam m\u00e0ng n\u00e3o v\u00e0 nhi\u1ec5m khu\u1ea9n ph\u1ed5i \u1edf b\u1ec7nh nh\u00e2n x\u01a1 nang<\/td>\n<td style=\"width: 23.8431%;\">2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>L\u01b0u \u00fd: Khi d\u00f9ng Meropenem cho b\u1ec7nh nh\u00e2n nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p do Pseudomonas aeruginosa c\u1ea7n gi\u00e1m s\u00e1t th\u01b0\u1eddng xuy\u00ean kh\u1ea3 n\u0103ng nh\u1ea1y c\u1ea3m c\u1ee7a vi khu\u1ea9n n\u00e0y v\u1edbi thu\u1ed1c.<\/p>\n<p>Ph\u01b0\u01a1ng ph\u00e1p ti\u00eam:<\/p>\n<p>Ti\u00eam t\u0129nh m\u1ea1ch tr\u1ef1c ti\u1ebfp (bolus) trong kho\u1ea3ng h\u01a1n 5 ph\u00fat ho\u1eb7c truy\u1ec1n t\u0129nh m\u1ea1ch t\u1eeb 15-30 ph\u00fat.<\/p>\n<p>Ng\u01b0\u1eddi l\u1edbn suy th\u1eadn<\/p>\n<p>Gi\u1ea3m li\u1ec1u \u1edf b\u1ec7nh nh\u00e2n c\u00f3 \u0111\u1ed9 thanh th\u1ea3i creatinin d\u01b0\u1edbi 51 ml\/ph\u00fat:<\/p>\n<ul>\n<li>26-50 ml\/ph\u00fat: 1 \u0111\u01a1n v\u1ecb li\u1ec1u c\u00e1ch 12 gi\u1edd<\/li>\n<li>10-25 ml\/ph\u00fat: \u00bd \u0111\u01a1n v\u1ecb li\u1ec1u c\u00e1ch 12 gi\u1edd<\/li>\n<li>&lt;10 ml\/ph\u00fat: \u00bd \u0111\u01a1n v\u1ecb li\u1ec1u c\u00e1ch 24 gi\u1edd<\/li>\n<\/ul>\n<p>\u0110\u1ec3 \u0111\u1ea3m b\u1ea3o n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00e1u lu\u00f4n \u1ed5n \u0111\u1ecbnh, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o, c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u d\u00f9ng Meropenem v\u00e0 c\u00f3 th\u1ec3 c\u1ea7n b\u1ed5 sung th\u00eam 1 li\u1ec1u sau m\u1ed7i l\u1ea7n l\u1ecdc m\u00e1u.<\/p>\n<p>Ng\u01b0\u1eddi l\u1edbn suy gan: Kh\u00f4ng c\u1ea7n ch\u1ec9nh li\u1ec1u.<\/p>\n<p>Ng\u01b0\u1eddi cao tu\u1ed5i: Kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u n\u1ebfu ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng ho\u1eb7c \u0111\u1ed9 thanh th\u1ea3i creatinine tr\u00ean 50 ml\/ph\u00fat.<\/p>\n<p>Tr\u1ebb em<\/p>\n<ul>\n<li>3 th\u00e1ng \u0111\u1ebfn 12 tu\u1ed5i: D\u00f9ng 10-40 mg\/kg m\u1ed7i 8 gi\u1edd t\u00f9y lo\u1ea1i nhi\u1ec5m khu\u1ea9n v\u00e0 t\u00ecnh tr\u1ea1ng b\u1ec7nh.<\/li>\n<li>Tr\u1ecdng l\u01b0\u1ee3ng &gt; 50kg: D\u00f9ng li\u1ec1u t\u01b0\u01a1ng \u0111\u01b0\u01a1ng ng\u01b0\u1eddi l\u1edbn.<\/li>\n<li>S\u1ed1t gi\u1ea3m b\u1ea1ch c\u1ea7u: Li\u1ec1u khuy\u1ebfn ngh\u1ecb l\u00e0 40 mg\/kg x 3 l\u1ea7n\/ng\u00e0y.<\/li>\n<\/ul>\n<p>Ti\u00eam t\u0129nh m\u1ea1ch tr\u1ef1c ti\u1ebfp (bolus) trong h\u01a1n 5 ph\u00fat ho\u1eb7c truy\u1ec1n t\u1eeb 15-30 ph\u00fat.<\/p>\n<p>H\u01b0\u1edbng d\u1eabn pha dung d\u1ecbch ti\u00eam truy\u1ec1n Pizulen 1g:<\/p>\n<ul>\n<li>Ti\u00eam bolus: Pha Meropenem v\u1edbi n\u01b0\u1edbc pha ti\u00eam (5ml cho m\u1ed7i 250mg), t\u1ea1o dung d\u1ecbch 50 mg\/ml.<\/li>\n<li>Truy\u1ec1n t\u0129nh m\u1ea1ch: Pha v\u1edbi 50-200ml NaCl 0,9% ho\u1eb7c dung d\u1ecbch t\u01b0\u01a1ng th\u00edch kh\u00e1c.<\/li>\n<li>B\u1ea3o qu\u1ea3n: S\u1eed d\u1ee5ng ngay sau khi pha. N\u1ebfu c\u1ea7n, c\u00f3 th\u1ec3 b\u1ea3o qu\u1ea3n \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng d\u01b0\u1edbi 25\u00b0C ho\u1eb7c trong t\u1ee7 l\u1ea1nh d\u01b0\u1edbi 4\u00b0C, kh\u00f4ng \u0111\u01b0\u1ee3c \u0111\u1ec3 \u0111\u00f4ng l\u1ea1nh.<\/li>\n<li>Kh\u00f4ng tr\u1ed9n l\u1eabn ho\u1eb7c k\u1ebft h\u1ee3p Pizulen v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c.<\/li>\n<\/ul>\n<figure id=\"attachment_108488\" aria-describedby=\"caption-attachment-108488\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-108488\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/01\/pizulen-1g-11.jpg\" alt=\"Thu\u1ed1c Pizulen 1g\" width=\"1200\" height=\"1200\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/01\/pizulen-1g-11.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/01\/pizulen-1g-11-400x400.jpg 400w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/01\/pizulen-1g-11-800x800.jpg 800w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/01\/pizulen-1g-11-280x280.jpg 280w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/01\/pizulen-1g-11-768x768.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/01\/pizulen-1g-11-350x350.jpg 350w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/01\/pizulen-1g-11-100x100.jpg 100w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-108488\" class=\"wp-caption-text\">Thu\u1ed1c Pizulen 1g d\u00e0nh cho \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0o?<\/figcaption><\/figure>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Pizulen 1g trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng <strong>Pizulen 1000mg<\/strong> cho b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi meropenem, carbapenem ho\u1eb7c c\u00e1c kh\u00e1ng sinh nh\u00f3m beta-lactam.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Pizulen 1g<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Ng\u01b0\u1eddi t\u1eebng d\u1ecb \u1ee9ng v\u1edbi penicillin ho\u1eb7c c\u00e1c kh\u00e1ng sinh beta-lactam kh\u00e1c c\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng Pizulen do nguy c\u01a1 ph\u1ea3n \u1ee9ng ch\u00e9o.<\/p>\n<p>Nh\u01b0 nhi\u1ec1u kh\u00e1ng sinh kh\u00e1c, vi\u1ec7c ph\u00e1t tri\u1ec3n qu\u00e1 m\u1ee9c c\u00e1c ch\u1ee7ng vi khu\u1ea9n kh\u00e1ng thu\u1ed1c c\u00f3 th\u1ec3 x\u1ea3y ra n\u00ean c\u1ea7n gi\u00e1m s\u00e1t b\u1ec7nh nh\u00e2n th\u01b0\u1eddng xuy\u00ean.<\/p>\n<p>Tr\u00e1nh s\u1eed d\u1ee5ng thu\u1ed1c Pizulen 1g cho b\u1ec7nh nh\u00e2n nhi\u1ec5m Staphylococcus kh\u00e1ng methicillin (MRSA).<\/p>\n<p>M\u1eb7c d\u00f9 hi\u1ebfm g\u1eb7p, vi\u00eam \u0111\u1ea1i tr\u00e0ng gi\u1ea3 m\u1ea1c v\u1eabn c\u00f3 th\u1ec3 x\u1ea3y ra khi s\u1eed d\u1ee5ng Pizulen v\u00e0 c\u1ea7n \u0111\u01b0\u1ee3c xem x\u00e9t n\u1ebfu b\u1ec7nh nh\u00e2n xu\u1ea5t hi\u1ec7n tri\u1ec7u ch\u1ee9ng ti\u00eau ch\u1ea3y.<\/p>\n<p>Khi s\u1eed d\u1ee5ng Pizulen, c\u1ea7n th\u1eadn tr\u1ecdng v\u1edbi b\u1ec7nh nh\u00e2n suy th\u1eadn ho\u1eb7c \u0111ang s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c c\u00f3 kh\u1ea3 n\u0103ng g\u00e2y h\u1ea1i cho th\u1eadn.<\/p>\n<p>Kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng thu\u1ed1c Pizulen 1g cho tr\u1ebb em d\u01b0\u1edbi 3 th\u00e1ng tu\u1ed5i do ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u v\u1ec1 \u0111\u1ed9 an to\u00e0n.<\/p>\n<h2>T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/h2>\n<p>Ph\u1ea3n \u1ee9ng t\u1ea1i v\u1ecb tr\u00ed ti\u00eam: Vi\u00eam t\u1ea1i ch\u1ed7, vi\u00eam t\u0129nh m\u1ea1ch huy\u1ebft kh\u1ed1i, \u0111au<\/p>\n<p>Ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng to\u00e0n th\u00e2n: Ph\u00f9 m\u1ea1ch, s\u1ed1c ph\u1ea3n v\u1ec7<\/p>\n<p>Da: Ban \u0111\u1ecf, ng\u1ee9a, m\u1ec1 \u0111ay; hi\u1ebfm khi c\u00f3 ban \u0111\u1ecf \u0111a h\u00ecnh, h\u1ed9i ch\u1ee9ng Steven Johnson, ho\u1ea1i t\u1eed da<\/p>\n<p>Ti\u00eau h\u00f3a: \u0110au b\u1ee5ng, n\u00f4n nao, \u00f3i, \u1ec9a ch\u1ea3y<\/p>\n<p>Huy\u1ebft h\u1ecdc: Ti\u1ec3u c\u1ea7u t\u0103ng, t\u0103ng eosinophil, gi\u1ea3m ti\u1ec3u c\u1ea7u, b\u1ea1ch c\u1ea7u gi\u1ea3m, gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh<\/p>\n<p>D\u01b0\u01a1ng t\u00ednh th\u1eed nghi\u1ec7m Coombs, gi\u1ea3m th\u1eddi gian thromboplastin<\/p>\n<p>Ch\u1ee9c n\u0103ng gan: T\u0103ng bilirubin, transaminase, ALP, lactate dehydrogenase<\/p>\n<p>H\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng: R\u1ed1i lo\u1ea1n c\u1ea3m gi\u00e1c, nh\u1ee9c \u0111\u1ea7u; hi\u1ebfm khi c\u00f3 co gi\u1eadt (ch\u01b0a x\u00e1c \u0111\u1ecbnh quan h\u1ec7 nh\u00e2n qu\u1ea3)<\/p>\n<p>Kh\u00e1c: Nhi\u1ec5m Candida \u00e2m \u0111\u1ea1o v\u00e0 mi\u1ec7ng<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h3>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 22.5684%;\">T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/td>\n<td style=\"width: 45.2313%;\">\u1ea2nh h\u01b0\u1edfng<\/td>\n<td style=\"width: 32.2002%;\">Khuy\u1ebfn c\u00e1o<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 22.5684%;\">Probenecid<\/td>\n<td style=\"width: 45.2313%;\">\u1ee8c ch\u1ebf b\u00e0i ti\u1ebft Meropenem qua th\u1eadn, l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 v\u00e0 T\u00bd c\u1ee7a Meropenem<\/td>\n<td style=\"width: 32.2002%;\">Kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 22.5684%;\">Acid valproic<\/td>\n<td style=\"width: 45.2313%;\">N\u1ed3ng \u0111\u1ed9 Acid Valproic trong huy\u1ebft thanh gi\u1ea3m<\/td>\n<td style=\"width: 32.2002%;\">C\u1ea7n theo d\u00f5i n\u1ed3ng \u0111\u1ed9 Acid Valproic<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 22.5684%;\">C\u00e1c thu\u1ed1c kh\u00e1c<\/td>\n<td style=\"width: 45.2313%;\">Ch\u01b0a c\u00f3 b\u00e1o c\u00e1o v\u1ec1 t\u01b0\u01a1ng t\u00e1c \u0111\u00e1ng k\u1ec3<\/td>\n<td style=\"width: 32.2002%;\">Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c, \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00e1c thu\u1ed1c c\u00f3 li\u00ean quan \u0111\u1ebfn ch\u1ee9c n\u0103ng th\u1eadn ho\u1eb7c gan<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/h3>\n<p>Pizulen c\u00f3 th\u1ec3 b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9. Do \u0111\u00f3, kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng thu\u1ed1c cho ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa tr\u1eeb khi l\u1ee3i \u00edch \u0111i\u1ec1u tr\u1ecb cho m\u1eb9 l\u1edbn h\u01a1n nguy c\u01a1 \u0111\u1ed1i v\u1edbi tr\u1ebb.&#8221;<\/p>\n<p>N\u00ean t\u1ea1m ng\u1eebng cho con b\u00fa ho\u1eb7c ng\u01b0ng s\u1eed d\u1ee5ng thu\u1ed1c khi \u0111ang \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Pizulen. H\u00e3y tham kh\u1ea3o \u00fd ki\u1ebfn b\u00e1c s\u0129 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n c\u1ee5 th\u1ec3.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Vi\u1ec7c s\u1eed d\u1ee5ng qu\u00e1 li\u1ec1u Pizulen 1g c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00f4ng mong mu\u1ed1n. \u1ede nh\u1eefng b\u1ec7nh nh\u00e2n suy th\u1eadn, vi\u1ec7c \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u v\u00e0 c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 nh\u01b0 th\u1ea9m t\u00e1ch m\u00e1u c\u00f3 th\u1ec3 c\u1ea7n thi\u1ebft.<\/p>\n<h2>Thu\u1ed1c Pizulen 1g gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Thu\u1ed1c Pizulen 1g hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Pizulen 1g t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Pizulen 1g nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/meropenem-kabi-1g\/\">Thu\u1ed1c Meropenem Kabi 1g<\/a> do Facta Farmaceutici S.p.A s\u1ea3n xu\u1ea5t, gi\u00e1 kho\u1ea3ng 3.500.000\u0111\/h\u1ed9p, ch\u1ee9a Meropenem trihydrat 1g, l\u00e0 kh\u00e1ng sinh beta lactam ph\u1ed5 r\u1ed9ng di\u1ec7t khu\u1ea9n nh\u1edd \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p v\u00e1ch t\u1ebf b\u00e0o vi khu\u1ea9n Gram d\u01b0\u01a1ng, Gram \u00e2m v\u00e0 y\u1ebfm kh\u00ed, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam ph\u1ed5i n\u1eb7ng, vi\u00eam m\u00e0ng n\u00e3o, nhi\u1ec5m tr\u00f9ng \u1ed5 b\u1ee5ng, ti\u1ebft ni\u1ec7u, da, ph\u1ebf qu\u1ea3n-ph\u1ed5i v\u00e0 nhi\u1ec5m tr\u00f9ng sau sinh \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em tr\u00ean 3 th\u00e1ng tu\u1ed5i.<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/meronem-1g\/\">Thu\u1ed1c Meronem 1g<\/a> do ACS Dobfar S.P.A s\u1ea3n xu\u1ea5t, gi\u00e1 kho\u1ea3ng 680.000\u0111\/h\u1ed9p, ch\u1ee9a Meropenem trihydrat 1g thu\u1ed9c nh\u00f3m kh\u00e1ng sinh carbapenem, ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p th\u00e0nh t\u1ebf b\u00e0o vi khu\u1ea9n, c\u00f3 ph\u1ed5 kh\u00e1ng khu\u1ea9n r\u1ed9ng g\u1ed3m vi khu\u1ea9n Gram \u00e2m, Gram d\u01b0\u01a1ng, hi\u1ebfu kh\u00ed v\u00e0 k\u1ef5 kh\u00ed, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam ph\u1ed5i, vi\u00eam m\u00e0ng n\u00e3o, nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u, \u1ed5 b\u1ee5ng, da, m\u00f4 m\u1ec1m, ph\u1ee5 khoa v\u00e0 nhi\u1ec5m khu\u1ea9n huy\u1ebft do vi khu\u1ea9n nh\u1ea1y c\u1ea3m.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>Nadine A Steffens, Estevan S Zimmermann, Sabrina M Nichelle, Nat\u00e1lia Brucker. (Th\u00e1ng 6 n\u0103m 2021). <em>Meropenem use and therapeutic drug monitoring in clinical practice: a literature review.<\/em> Truy c\u1eadp ng\u00e0y 11 th\u00e1ng 1 n\u0103m 2025, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33533509\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33533509\/<\/a><\/li>\n<li>Zhenwei Yu, Xiaoping Pang, Xuqi Wu, Chunlei Shan, Saiping Jiang. (Ng\u00e0y 30 th\u00e1ng 7 n\u0103m 2018). <em>Clinical outcomes of prolonged infusion (extended infusion or continuous infusion) versus intermittent bolus of meropenem in severe infection: A meta-analysis<\/em>. Truy c\u1eadp ng\u00e0y 11 th\u00e1ng 1 n\u0103m 2025, t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30059536\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30059536\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Pizulen 1g \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb m\u1ed9t lo\u1ea1t c\u00e1c b\u1ec7nh nhi\u1ec5m tr\u00f9ng nghi\u00eam tr\u1ecdng, t\u1eeb nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p nh\u01b0 vi\u00eam ph\u1ed5i \u0111\u1ebfn nhi\u1ec5m khu\u1ea9n to\u00e0n th\u00e2n nh\u01b0 nhi\u1ec5m khu\u1ea9n huy\u1ebft<\/p>\n","protected":false},"author":1,"featured_media":108462,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-108454","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/108454","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=108454"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/108462"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=108454"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=108454"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=108454"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}