{"id":108279,"date":"2025-01-08T15:57:43","date_gmt":"2025-01-08T08:57:43","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=108279"},"modified":"2025-07-24T13:22:44","modified_gmt":"2025-07-24T06:22:44","slug":"trajenta-duo-25mg-850mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/trajenta-duo-25mg-850mg\/","title":{"rendered":"Trajenta Duo 2,5mg\/850mg"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Trajenta Duo 2,5mg\/850mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Boehringer Ingelheim Promeco S.A. de C.V, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 750110167400<\/strong><\/p>\n

Trajenta Duo 2,5mg\/850mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n
Th\u00e0nh ph\u1ea7n<\/h3>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/850mg<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n
\n
Linagliptin 2,5mg<\/li>\n
Metformin hydrochloride 850mg<\/li>\n
T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean<\/li>\n<\/ul>\n
D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n
Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: 750110167400<\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd 14 vi\u00ean; H\u1ed9p 1 l\u1ecd 60 vi\u00ean<\/p>\n
Xu\u1ea5t x\u1ee9: Mexico<\/p>\n
T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Trajenta Duo 2,5mg\/850mg<\/h2>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n
Linagliptin, m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf DPP-4 ch\u1ecdn l\u1ecdc cao, ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf s\u1ef1 ph\u00e2n h\u1ee7y c\u1ee7a c\u00e1c hormone incretin nh\u01b0 GLP-1 v\u00e0 GIP. \u0110i\u1ec1u n\u00e0y d\u1eabn \u0111\u1ebfn t\u0103ng n\u1ed3ng \u0111\u1ed9 v\u00e0 k\u00e9o d\u00e0i th\u1eddi gian t\u1ed3n t\u1ea1i c\u1ee7a c\u00e1c hormone n\u00e0y, t\u1eeb \u0111\u00f3 t\u0103ng c\u01b0\u1eddng b\u00e0i ti\u1ebft insulin ph\u1ee5 thu\u1ed9c glucose v\u00e0 \u1ee9c ch\u1ebf b\u00e0i ti\u1ebft glucagon, c\u1ea3i thi\u1ec7n ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft.<\/p>\n
Metformin l\u00e0 m\u1ed9t biguanide c\u00f3 t\u00e1c d\u1ee5ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft \u0111a chi\u1ec1u. Thu\u1ed1c gi\u1ea3m s\u1ea3n sinh glucose \u1edf gan th\u00f4ng qua \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh gluconeogenesis v\u00e0 glycogenolysis. \u0110\u1ed3ng th\u1eddi, metformin t\u0103ng c\u01b0\u1eddng s\u1eed d\u1ee5ng glucose \u1edf ngo\u1ea1i bi\u00ean b\u1eb1ng c\u00e1ch c\u1ea3i thi\u1ec7n \u0111\u1ed9 nh\u1ea1y c\u1ea3m v\u1edbi insulin v\u00e0 \u1ee9c ch\u1ebf h\u1ea5p thu glucose \u1edf ru\u1ed9t.<\/p>\n
\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n\n\n\n\n\n\n\n\n
D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/strong><\/td>\n Linagliptin<\/strong><\/td>\n Metformin<\/strong><\/td>\n<\/tr>\n
H\u1ea5p thu<\/td>\n Sinh kh\u1ea3 d\u1ee5ng kho\u1ea3ng 30%.<\/p>\n
C\u00f3 th\u1ec3 d\u00f9ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng v\u1edbi th\u1ee9c \u0103n.<\/td>\n
Sinh kh\u1ea3 d\u1ee5ng 50-60%.<\/p>\n
H\u1ea5p thu kh\u00f4ng ho\u00e0n to\u00e0n, c\u00f3 th\u1ec3 b\u00e3o h\u00f2a.<\/td>\n<\/tr>\n
Ph\u00e2n b\u1ed1<\/td>\n R\u1ed9ng r\u00e3i \u0111\u1ebfn c\u00e1c m\u00f4.<\/p>\n
Li\u00ean k\u1ebft protein huy\u1ebft t\u01b0\u01a1ng ph\u1ee5 thu\u1ed9c n\u1ed3ng \u0111\u1ed9.<\/td>\n
Kh\u00f4ng g\u1eafn \u0111\u00e1ng k\u1ec3 v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng.<\/p>\n
Ph\u00e2n b\u1ed1 v\u00e0o h\u1ed3ng c\u1ea7u.<\/td>\n<\/tr>\n
Chuy\u1ec3n h\u00f3a<\/td>\n Chuy\u1ec3n h\u00f3a \u00edt.<\/p>\n
Ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh d\u01b0\u1ee3c l\u00fd.<\/td>\n
Kh\u00f4ng c\u00f3 ch\u1ea5t chuy\u1ec3n h\u00f3a \u1edf ng\u01b0\u1eddi.<\/td>\n<\/tr>\n
Th\u1ea3i tr\u1eeb<\/td>\n Qua ph\u00e2n (80%) v\u00e0 n\u01b0\u1edbc ti\u1ec3u (5%).<\/p>\n
Thanh th\u1ea3i qua th\u1eadn kho\u1ea3ng 70ml\/ph\u00fat.<\/td>\n
Ho\u00e0n to\u00e0n qua th\u1eadn d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i.<\/p>\n
Thanh th\u1ea3i qua th\u1eadn >400ml\/ph\u00fat.<\/td>\n<\/tr>\n
\u1ea2nh h\u01b0\u1edfng c\u1ee7a b\u1ec7nh l\u00fd<\/td>\n Suy gan\/th\u1eadn: Kh\u00f4ng c\u1ea7n ch\u1ec9nh li\u1ec1u<\/td>\n Suy th\u1eadn: C\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u<\/p>\n
Suy gan: Kh\u00f4ng c\u1ea7n ch\u1ec9nh li\u1ec1u<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/850mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n
Thu\u1ed1c Trajenta Duo<\/strong> 2.5mg\/850mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh nh\u01b0 m\u1ed9t li\u1ec7u ph\u00e1p k\u1ebft h\u1ee3p \u0111\u1ec3 c\u1ea3i thi\u1ec7n ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft \u1edf b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng type 2 tr\u01b0\u1edfng th\u00e0nh, bao g\u1ed3m nh\u1eefng b\u1ec7nh nh\u00e2n ch\u01b0a \u0111\u1ea1t \u0111\u01b0\u1ee3c m\u1ee5c ti\u00eau ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft khi \u0111i\u1ec1u tr\u1ecb b\u1eb1ng metformin \u0111\u01a1n tr\u1ecb ho\u1eb7c khi k\u1ebft h\u1ee3p linagliptin v\u00e0 metformin ri\u00eang l\u1ebb.<\/p>\n
Ngo\u00e0i ra, thu\u1ed1c Trajenta Duo 2,5mg\/850mg c\u00f2n \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh k\u1ebft h\u1ee3p v\u1edbi sulfonylurea \u0111\u1ec3 t\u0103ng c\u01b0\u1eddng hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n ch\u01b0a ki\u1ec3m so\u00e1t t\u1ed1t \u0111\u01b0\u1eddng huy\u1ebft.<\/p>\n
Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Trajenta Duo 2,5mg\/850mg<\/h2>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/850mg n\u00ean \u0111\u01b0\u1ee3c u\u1ed1ng nguy\u00ean vi\u00ean c\u00f9ng v\u1edbi b\u1eefa \u0103n, v\u00e0 n\u00e2ng li\u1ec1u t\u1eeb t\u1eeb theo ch\u1ec9 d\u1eabn c\u1ee7a b\u00e1c s\u0129 \u0111\u1ec3 gi\u1ea3m thi\u1ec3u c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 l\u00ean \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/p>\n
$\"Thu\u1ed1c$
Thu\u1ed1c Trajenta Duo 2,5mg\/850mg d\u00e0nh cho \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0o?<\/figcaption><\/figure>\n
Li\u1ec1u d\u00f9ng<\/p>\n\n\n\n\n\n\n\n\n\n\n\n
\u0110\u1ed1i t\u01b0\u1ee3ng<\/td>\n Li\u1ec1u kh\u1edfi \u0111\u1ea7u<\/td>\n Li\u1ec1u t\u1ed1i \u0111a<\/td>\n<\/tr>\n
M\u1edbi d\u00f9ng metformin<\/td>\n 1 vi\u00ean Trajenta Duo 2,5mg\/850mg x 2 l\u1ea7n\/ng\u00e0y<\/td>\n 5mg linagliptin\/ 2000mg metformin<\/td>\n<\/tr>\n
Ch\u01b0a ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft t\u1ed1t v\u1edbi Metformin \u0111\u01a1n tr\u1ecb<\/td>\n Linagliptin 2,5mg x 2 l\u1ea7n\/ng\u00e0y<\/p>\n
Metformin: duy tr\u00ec li\u1ec1u hi\u1ec7n t\u1ea1i<\/td>\n<\/tr>\n
Chuy\u1ec3n t\u1eeb ph\u1ed1i h\u1ee3p Linagliptin v\u00e0 Metformin ri\u00eang l\u1ebb<\/td>\n B\u1eaft \u0111\u1ea7u \u1edf li\u1ec1u \u0111ang d\u00f9ng<\/td>\n<\/tr>\n
Ch\u01b0a ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft t\u1ed1t v\u1edbi Metformin v\u00e0 Sulfonylurea<\/td>\n Linagliptin 2,5mg x 2 l\u1ea7n\/ng\u00e0y<\/p>\n
Metformin: duy tr\u00ec li\u1ec1u hi\u1ec7n t\u1ea1i<\/p>\n
Sulfonylurea: c\u00f3 th\u1ec3 gi\u1ea3m li\u1ec1u<\/td>\n<\/tr>\n
Suy th\u1eadn (CrCl 45-59 mL\/ph\u00fat)<\/td>\n Metformin t\u1ed1i \u0111a 500mg x 2 l\u1ea7n\/ng\u00e0y<\/td>\n 5mg linagliptin\/ 1000mg metformin<\/td>\n<\/tr>\n
Ng\u01b0\u1eddi cao tu\u1ed5i<\/td>\n Theo li\u1ec1u khuy\u1ebfn c\u00e1o<\/td>\n 5mg linagliptin\/ 2000mg metformin<\/td>\n<\/tr>\n
Suy gan<\/td>\n Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh<\/td>\n –<\/td>\n<\/tr>\n
Tr\u1ebb em v\u00e0 thanh thi\u1ebfu ni\u00ean<\/td>\n Kh\u00f4ng khuy\u1ebfn c\u00e1o<\/td>\n –<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Trajenta Duo 2,5mg\/850mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/850mg<\/strong> kh\u00f4ng d\u00f9ng cho:<\/p>\n
\n
D\u1ecb \u1ee9ng v\u1edbi linagliptin ho\u1eb7c metformin ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n ph\u1ee5 n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n
Toan ceton do \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng<\/li>\n
Giai \u0111o\u1ea1n ti\u1ec1n h\u00f4n m\u00ea do ti\u1ec3u \u0111\u01b0\u1eddng<\/li>\n
Th\u1eadn ho\u1ea1t \u0111\u1ed9ng k\u00e9m, kh\u1ea3 n\u0103ng l\u1ecdc th\u1ea3i ch\u1ea5t th\u1ea3i gi\u1ea3m s\u00fat nghi\u00eam tr\u1ecdng, t\u1ed5n th\u01b0\u01a1ng th\u1eadn \u1edf m\u1ee9c \u0111\u1ed9 cao<\/li>\n
T\u1ed5n th\u01b0\u01a1ng gan<\/li>\n
L\u1ea1m d\u1ee5ng r\u01b0\u1ee3u<\/li>\n
Ng\u1ed9 \u0111\u1ed9c r\u01b0\u1ee3u c\u1ea5p t\u00ednh<\/li>\n
C\u00e1c b\u1ec7nh l\u00fd g\u00e2y thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9 m\u00f4, t\u00ecnh tr\u1ea1ng gi\u1ea3m oxy cung c\u1ea5p cho c\u00e1c t\u1ebf b\u00e0o, suy gi\u1ea3m ch\u1ee9c n\u0103ng c\u00e1c c\u01a1 quan do thi\u1ebfu oxy<\/li>\n
C\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 g\u00e2y t\u1ed5n th\u01b0\u01a1ng th\u1eadn c\u1ea5p t\u00ednh bao g\u1ed3m: m\u1ea5t n\u01b0\u1edbc nghi\u00eam tr\u1ecdng, nhi\u1ec5m tr\u00f9ng to\u00e0n th\u00e2n, s\u1ed1c huy\u1ebft \u00e1p, ti\u00eam thu\u1ed1c c\u1ea3n quang<\/li>\n<\/ul>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Trajenta Duo 2,5mg\/850mg<\/h2>\n
Th\u1eadn tr\u1ecdng<\/h3>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/850mg kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng cho b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 1 v\u00e0 nh\u1eefng ng\u01b0\u1eddi \u0111ang b\u1ecb nhi\u1ec5m toan ceton.<\/p>\n
Khi k\u1ebft h\u1ee3p Trajenta Duo 2,5mg\/850mg v\u1edbi insulin, \u0111\u1eb7c bi\u1ec7t \u1edf nh\u1eefng ng\u01b0\u1eddi b\u1ecb suy th\u1eadn n\u1eb7ng, nguy c\u01a1 \u0111\u01b0\u1eddng huy\u1ebft gi\u1ea3m qu\u00e1 th\u1ea5p s\u1ebd cao h\u01a1n. V\u00ec v\u1eady, c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u l\u01b0\u1ee3ng insulin \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n.<\/p>\n
Ng\u01b0\u1eddi cao tu\u1ed5i, ng\u01b0\u1eddi \u1ed1m y\u1ebfu ho\u1eb7c c\u00f3 c\u00e1c b\u1ec7nh l\u00fd n\u1ec1n nh\u01b0 suy tuy\u1ebfn y\u00ean, th\u01b0\u1ee3ng th\u1eadn c\u0169ng d\u1ec5 b\u1ecb h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft khi s\u1eed d\u1ee5ng thu\u1ed1c n\u00e0y.<\/p>\n
Ng\u01b0\u1eddi cao tu\u1ed5i v\u00e0 b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng thu\u1ed1c ch\u1eb9n beta c\u00f3 th\u1ec3 kh\u00f4ng nh\u1eadn bi\u1ebft \u0111\u01b0\u1ee3c c\u00e1c tri\u1ec7u ch\u1ee9ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft.<\/p>\n
Suy th\u1eadn, tu\u1ed5i cao, b\u1ec7nh l\u00fd tim m\u1ea1ch, s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi ch\u1ea5t \u1ee9c ch\u1ebf carbonic anhydrase, t\u00ecnh tr\u1ea1ng gi\u1ea3m oxy h\u00f3a v\u00e0 c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 kh\u00e1c l\u00e0 nh\u1eefng \u0111i\u1ec1u ki\u1ec7n thu\u1eadn l\u1ee3i d\u1eabn \u0111\u1ebfn nhi\u1ec5m toan lactic khi s\u1eed d\u1ee5ng metformin.<\/p>\n
Nguy c\u01a1 nhi\u1ec5m toan lactic do metformin gia t\u0103ng \u0111\u00e1ng k\u1ec3 \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn. Kh\u1ea3 n\u0103ng th\u1ea3i tr\u1eeb metformin qua th\u1eadn suy gi\u1ea3m d\u1eabn \u0111\u1ebfn t\u00edch t\u1ee5 thu\u1ed1c v\u00e0 t\u0103ng nguy c\u01a1 bi\u1ebfn ch\u1ee9ng n\u00e0y. Do \u0111\u00f3, vi\u1ec7c \u0111\u00e1nh gi\u00e1 ch\u1ee9c n\u0103ng th\u1eadn tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u v\u00e0 trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb b\u1eb1ng metformin l\u00e0 v\u00f4 c\u00f9ng quan tr\u1ecdng.<\/p>\n
Vi\u1ec7c s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi metformin v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c ho\u1eb7c th\u1ef1c hi\u1ec7n c\u00e1c x\u00e9t nghi\u1ec7m ch\u1ea9n \u0111o\u00e1n, ph\u1eabu thu\u1eadt c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m toan lactic, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n cao tu\u1ed5i v\u00e0 suy th\u1eadn. Do \u0111\u00f3, c\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng metformin \u1edf nh\u1eefng \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y v\u00e0 t\u1ea1m d\u1eebng thu\u1ed1c tr\u01b0\u1edbc khi th\u1ef1c hi\u1ec7n c\u00e1c th\u1ee7 thu\u1eadt x\u00e2m l\u1ea5n.<\/p>\n
C\u00e1c t\u00ecnh tr\u1ea1ng thi\u1ebfu oxy nh\u01b0 suy tim c\u1ea5p, s\u1ed1c, nhi\u1ec5m tr\u00f9ng n\u1eb7ng l\u00e0m t\u0103ng \u0111\u00e1ng k\u1ec3 nguy c\u01a1 nhi\u1ec5m toan lactic khi s\u1eed d\u1ee5ng Metformin, ph\u1ea3i th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng metformin \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n n\u00e0y v\u00e0 t\u1ea1m d\u1eebng thu\u1ed1c khi c\u00f3 c\u00e1c bi\u1ebfn c\u1ed1 tr\u00ean.<\/p>\n
Vi\u1ec7c ti\u00eau th\u1ee5 r\u01b0\u1ee3u v\u00e0 suy gan l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m toan lactic khi s\u1eed d\u1ee5ng metformin do gi\u1ea3m kh\u1ea3 n\u0103ng chuy\u1ec3n h\u00f3a lactate, ph\u1ea3i th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng metformin \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n n\u00e0y v\u00e0 c\u00e2n nh\u1eafc k\u1ef9 l\u01b0\u1ee1ng l\u1ee3i \u00edch v\u00e0 nguy h\u1ea1i tr\u01b0\u1edbc khi quy\u1ebft \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n
C\u00f3 tr\u01b0\u1eddng h\u1ee3p b\u1ec7nh nh\u00e2n d\u00f9ng thu\u1ed1c Linagliptin b\u1ecb vi\u00eam t\u1ee5y, ph\u1ea3i ch\u00fa \u00fd \u0111\u1ebfn c\u00e1c d\u1ea5u hi\u1ec7u c\u1ee7a b\u1ec7nh n\u00e0y.<\/p>\n
Ng\u01b0\u1eddi b\u1ec7nh suy tim m\u00e3n t\u00ednh c\u00f3 th\u1ec3 d\u00f9ng thu\u1ed1c nh\u01b0ng c\u1ea7n theo d\u00f5i s\u1ee9c kh\u1ecfe th\u01b0\u1eddng xuy\u00ean. Tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng d\u00f9ng thu\u1ed1c n\u00e0y cho ng\u01b0\u1eddi b\u1ec7nh suy tim c\u1ea5p ho\u1eb7c kh\u00f4ng \u1ed5n \u0111\u1ecbnh.<\/p>\n
Vi\u1ec7c d\u00f9ng Linagliptin ti\u1ec1m \u1ea9n nguy c\u01a1 g\u00e2y b\u1ec7nh b\u1ecdng n\u01b0\u1edbc pemphigoid, \u0111\u00f2i h\u1ecfi b\u1ec7nh nh\u00e2n c\u1ea7n theo d\u00f5i s\u00e1t sao v\u00e0 ng\u1eebng thu\u1ed1c Trajenta Duo 2,5mg\/850mg khi c\u1ea7n thi\u1ebft; \u0111\u1ed3ng th\u1eddi, ch\u01b0a c\u00f3 \u0111\u1ee7 b\u1eb1ng ch\u1ee9ng v\u1ec1 t\u00e1c \u0111\u1ed9ng c\u1ee7a thu\u1ed1c l\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe.<\/p>\n
T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/h3>\n
Chuy\u1ec3n h\u00f3a: R\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a acid lactic, suy gi\u1ea3m h\u1ea5p thu vitamin B12<\/p>\n
Da: Ng\u1ee9a, ban \u0111\u1ecf, n\u1ed5i m\u1ec1 \u0111ay, b\u1ecdng n\u01b0\u1edbc<\/p>\n
H\u00f4 h\u1ea5p: Vi\u00eam m\u0169i h\u1ecdng, ho<\/p>\n
Gan m\u1eadt: Suy gi\u1ea3m ch\u1ee9c n\u0103ng gan, vi\u00eam gan<\/p>\n
Mi\u1ec5n d\u1ecbch: Qu\u00e1 m\u1eabn, s\u01b0ng ph\u00f9 m\u1ea1ch<\/p>\n
Th\u1ea7n kinh: V\u1ecb gi\u00e1c r\u1ed1i lo\u1ea1n<\/p>\n
Ti\u00eau h\u00f3a: Ch\u00e1n \u0103n, \u0111au b\u1ee5ng, \u0111i ngo\u00e0i ph\u00e2n l\u1ecfng, bu\u1ed3n n\u00f4n, vi\u00eam t\u1ee5y, \u00f3i, lo\u00e9t mi\u1ec7ng<\/p>\n
T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h3>\n\n\n\n\n\n\n\n\n\n\n
Thu\u1ed1c<\/td>\n T\u01b0\u01a1ng t\u00e1c v\u1edbi<\/td>\n T\u00e1c d\u1ee5ng khi t\u01b0\u01a1ng t\u00e1c<\/td>\n L\u01b0u \u00fd<\/td>\n<\/tr>\n
Linagliptin<\/td>\n CYP3A4<\/td>\n \u1ee8c ch\u1ebf y\u1ebfu<\/td>\n \u00cdt \u1ea3nh h\u01b0\u1edfng l\u00e2m s\u00e0ng<\/td>\n<\/tr>\n
P-glycoprotein<\/td>\n \u1ee8c ch\u1ebf y\u1ebfu<\/td>\n \u00cdt \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1c c\u01a1 ch\u1ea5t P-gp kh\u00e1c<\/td>\n<\/tr>\n
Digoxin, Glibenclamide, Metformin, Pioglitazone, Simvastatin, Thu\u1ed1c tr\u00e1nh thai \u0111\u01b0\u1eddng u\u1ed1ng, Warfarin<\/td>\n Kh\u00f4ng c\u00f3 t\u01b0\u01a1ng t\u00e1c l\u00e2m s\u00e0ng \u0111\u00e1ng k\u1ec3<\/td>\n <\/td>\n<\/tr>\n
Metformin<\/td>\n R\u01b0\u1ee3u<\/td>\n T\u0103ng nguy c\u01a1 nhi\u1ec5m toan lactic<\/td>\n Tr\u00e1nh u\u1ed1ng r\u01b0\u1ee3u<\/td>\n<\/tr>\n
Thu\u1ed1c c\u1ea3n quang ch\u1ee9a iod<\/td>\n Suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn, g\u00e2y toan lactic<\/td>\n Ng\u1eebng d\u00f9ng metformin tr\u01b0\u1edbc khi ch\u1ee5p, \u0111\u00e1nh gi\u00e1 l\u1ea1i ch\u1ee9c n\u0103ng th\u1eadn sau ch\u1ee5p<\/td>\n<\/tr>\n
Thu\u1ed1c g\u1ed1c cation (Cimetidine)<\/td>\n C\u1ea1nh tranh h\u1ec7 th\u1ed1ng v\u1eadn chuy\u1ec3n \u1edf \u1ed1ng th\u1eadn<\/td>\n Theo d\u00f5i \u0111\u01b0\u1eddng huy\u1ebft, \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u<\/td>\n<\/tr>\n
Thu\u1ed1c \u1ee9c ch\u1ebf carbonic anhydrase (Acetazolamide, Dichlorphenamide, Topiramate, Zonisamide)<\/td>\n G\u00e2y toan chuy\u1ec3n h\u00f3a<\/td>\n Th\u1eadn tr\u1ecdng, c\u00f3 th\u1ec3 t\u0103ng nguy c\u01a1 nhi\u1ec5m toan lactic<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/h3>\n
Thai k\u1ef3: Trong qu\u00e1 tr\u00ecnh mang thai, vi\u1ec7c ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft b\u1eb1ng insulin l\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o \u0111\u1ec3 gi\u1ea3m thi\u1ec3u nguy c\u01a1 d\u1ecb t\u1eadt b\u1ea9m sinh \u1edf thai nhi. Do \u0111\u00f3, kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng Trajenta Duo 2,5mg\/850mg trong th\u1eddi k\u1ef3 n\u00e0y.<\/p>\n
Cho con b\u00fa: \u0110\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n cho tr\u1ebb s\u01a1 sinh, kh\u00f4ng n\u00ean d\u00f9ng Trajenta Duo 2,5mg\/850mg khi \u0111ang cho con b\u00fa. Metformin \u0111\u00e3 \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong s\u1eefa m\u1eb9, v\u00e0 vi\u1ec7c linagliptin c\u00f3 truy\u1ec1n qua s\u1eefa m\u1eb9 hay kh\u00f4ng v\u1eabn ch\u01b0a r\u00f5 r\u00e0ng.<\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n
Qu\u00e1 li\u1ec1u Linagliptin: Ngay c\u1ea3 khi d\u00f9ng li\u1ec1u linagliptin cao g\u1ea5p 120 l\u1ea7n li\u1ec1u khuy\u1ebfn c\u00e1o, ng\u01b0\u1eddi b\u1ec7nh v\u1eabn dung n\u1ea1p t\u1ed1t. Ch\u01b0a c\u00f3 b\u00e1o c\u00e1o v\u1ec1 c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng khi d\u00f9ng qu\u00e1 li\u1ec1u thu\u1ed1c n\u00e0y.<\/p>\n
Qu\u00e1 li\u1ec1u Metformin: Vi\u1ec7c d\u00f9ng qu\u00e1 li\u1ec1u metformin c\u00f3 th\u1ec3 g\u00e2y ra t\u00ecnh tr\u1ea1ng nhi\u1ec5m toan lactic, \u0111e d\u1ecda t\u00ednh m\u1ea1ng ng\u01b0\u1eddi b\u1ec7nh. Trong tr\u01b0\u1eddng h\u1ee3p n\u00e0y, c\u1ea7n ti\u1ebfn h\u00e0nh c\u00e1c bi\u1ec7n ph\u00e1p c\u1ea5p c\u1ee9u nh\u01b0 lo\u1ea1i b\u1ecf thu\u1ed1c ch\u01b0a h\u1ea5p thu v\u00e0 l\u1ecdc m\u00e1u.<\/p>\n
X\u1eed tr\u00ed qu\u00e1 li\u1ec1u: Trong tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u Trajenta Duo 2,5mg\/850mg, c\u00e1c bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 s\u1ebd \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n. Tuy nhi\u00ean, l\u1ecdc m\u00e1u l\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb \u0111\u1eb7c hi\u1ec7u v\u00e0 hi\u1ec7u qu\u1ea3 nh\u1ea5t \u0111\u1ec3 lo\u1ea1i b\u1ecf lactate v\u00e0 metformin, gi\u00fap ng\u0103n ng\u1eeba c\u00e1c bi\u1ebfn ch\u1ee9ng nghi\u00eam tr\u1ecdng.<\/p>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/850mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/850mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n
Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Trajenta Duo 2,5mg\/850mg t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Trajenta Duo 2,5mg\/850mg nh\u01b0:<\/p>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/500mg<\/strong><\/a> (Boehringer Ingelheim) l\u00e0 thu\u1ed1c k\u1ebft h\u1ee3p Linagliptin v\u00e0 Metformin, gi\u00fap ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft hi\u1ec7u qu\u1ea3 \u1edf ng\u01b0\u1eddi b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng type 2, ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch t\u0103ng c\u01b0\u1eddng s\u1ea3n xu\u1ea5t insulin, gi\u1ea3m s\u1ea3n xu\u1ea5t \u0111\u01b0\u1eddng \u1edf gan v\u00e0 t\u0103ng nh\u1ea1y c\u1ea3m c\u1ee7a t\u1ebf b\u00e0o v\u1edbi insulin, \u0111\u1eb7c bi\u1ec7t ph\u00f9 h\u1ee3p v\u1edbi nh\u1eefng tr\u01b0\u1eddng h\u1ee3p \u0111\u00e3 \u0111i\u1ec1u tr\u1ecb b\u1eb1ng c\u00e1c thu\u1ed1c \u0111\u01a1n l\u1ebb nh\u01b0ng ch\u01b0a \u0111\u1ea1t \u0111\u01b0\u1ee3c m\u1ee5c ti\u00eau.<\/p>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/1000mg<\/strong><\/a> (Boehringer Ingelheim) l\u00e0 thu\u1ed1c k\u1ebft h\u1ee3p Linagliptin v\u00e0 Metformin, gi\u00fap ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft hi\u1ec7u qu\u1ea3 \u1edf ng\u01b0\u1eddi b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng type 2, \u0111\u1eb7c bi\u1ec7t l\u00e0 nh\u1eefng tr\u01b0\u1eddng h\u1ee3p \u0111\u00e3 \u0111i\u1ec1u tr\u1ecb b\u1eb1ng c\u00e1c thu\u1ed1c \u0111\u01a1n l\u1ebb nh\u01b0ng ch\u01b0a \u0111\u1ea1t \u0111\u01b0\u1ee3c m\u1ee5c ti\u00eau.<\/p>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n\n
Andr\u00e9 J Scheen. (Ng\u00e0y 4 th\u00e1ng 2 n\u0103m 2013). Linagliptin plus metformin: a pharmacokinetic and pharmacodynamic evaluation<\/em>. Truy c\u1eadp ng\u00e0y 8 th\u00e1ng 1 n\u0103m 2025, t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/23373842\/ <\/a><\/li>\n
Qian Lv, Jie Shen, Lin Miao, Binqi Ye, Cornelia Schepers, Arian Plat, Yongquan Shi. (Ng\u00e0y 23 th\u00e1ng 4 n\u0103m 2020). Early Combination Therapy with Linagliptin and Metformin in People with Type 2 Diabetes Improves Glycemic Control to HbA1c \u2264 6.5% without Increasing Hypoglycemia: Pooled Analysis of Two Randomized Clinical Trial<\/em>s. Truy c\u1eadp ng\u00e0y 8 th\u00e1ng 1 n\u0103m 2025, t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/32328953\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"
Thu\u1ed1c Trajenta Duo 2,5mg\/850mg ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2 ch\u01b0a \u0111\u00e1p \u1ee9ng t\u1ed1t v\u1edbi metformin ho\u1eb7c c\u00e1c ph\u00e1c \u0111\u1ed3 k\u1ebft h\u1ee3p kh\u00e1c, nh\u1eb1m c\u1ea3i thi\u1ec7n ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft<\/p>\n","protected":false},"author":1,"featured_media":108282,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-108279","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-variable"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/108279","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=108279"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/108282"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=108279"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=108279"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=108279"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

Tr\u00ecnh b\u00e0y<\/h3>\nS\u0110K: 750110167400<\/p>\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd 14 vi\u00ean; H\u1ed9p 1 l\u1ecd 60 vi\u00ean<\/p>\nXu\u1ea5t x\u1ee9: Mexico<\/p>\n

T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Trajenta Duo 2,5mg\/850mg<\/h2>\n

L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Trajenta Duo 2,5mg\/850mg<\/h2>\n

Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: 750110167400<\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd 14 vi\u00ean; H\u1ed9p 1 l\u1ecd 60 vi\u00ean<\/p>\n
Xu\u1ea5t x\u1ee9: Mexico<\/p>\n