{"id":107338,"date":"2024-12-20T09:49:27","date_gmt":"2024-12-20T02:49:27","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=107338"},"modified":"2025-07-24T13:22:49","modified_gmt":"2025-07-24T06:22:49","slug":"trajenta-duo-25mg-500mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/trajenta-duo-25mg-500mg\/","title":{"rendered":"Trajenta Duo 2,5mg\/500mg"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Trajenta Duo 2,5mg\/500mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Boehringer Ingelheim Promeco S.A. de C.V, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 750110167200<\/strong><\/p>\n

Trajenta Duo 2,5mg\/500mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n
Th\u00e0nh ph\u1ea7n<\/h3>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/500mg<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n
\n
Linagliptin 2,5mg<\/li>\n
Metformin hydrochloride 500mg<\/li>\n
T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean<\/li>\n<\/ul>\n
D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n
Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: 750110167200<\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd 14 vi\u00ean<\/p>\n
Xu\u1ea5t x\u1ee9: Mexico<\/p>\n
T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Trajenta Duo 2,5mg\/500mg<\/h2>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n
Linagliptin<\/strong> ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch ng\u0103n ch\u1eb7n enzyme DPP-4 ph\u00e2n h\u1ee7y c\u00e1c hormone incretin t\u1ef1 nhi\u00ean c\u1ee7a c\u01a1 th\u1ec3. C\u00e1c hormone n\u00e0y c\u00f3 vai tr\u00f2 quan tr\u1ecdng trong vi\u1ec7c \u0111i\u1ec1u h\u00f2a l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u. Khi Linagliptin \u1ee9c ch\u1ebf DPP-4, l\u01b0\u1ee3ng hormone incretin t\u0103ng l\u00ean, d\u1eabn \u0111\u1ebfn:<\/p>\n
\n
T\u0103ng s\u1ea3n xu\u1ea5t insulin: C\u00e1c t\u1ebf b\u00e0o beta trong tuy\u1ebfn t\u1ee5y s\u1ebd s\u1ea3n xu\u1ea5t nhi\u1ec1u insulin h\u01a1n, \u0111\u1eb7c bi\u1ec7t khi l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u t\u0103ng cao. Insulin gi\u00fap \u0111\u01b0a glucose t\u1eeb m\u00e1u v\u00e0o t\u1ebf b\u00e0o \u0111\u1ec3 cung c\u1ea5p n\u0103ng l\u01b0\u1ee3ng.<\/li>\n
Gi\u1ea3m s\u1ea3n xu\u1ea5t glucose: Gan s\u1ebd gi\u1ea3m s\u1ea3n xu\u1ea5t glucose, gi\u00fap duy tr\u00ec m\u1ee9c \u0111\u01b0\u1eddng huy\u1ebft \u1ed5n \u0111\u1ecbnh.<\/li>\n<\/ul>\n
Metformin hydrochloride, m\u1ed9t \u0111\u1ea1i di\u1ec7n c\u1ee7a nh\u00f3m thu\u1ed1c biguanid, c\u00f3 t\u00e1c d\u1ee5ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft b\u1eb1ng c\u00e1ch gi\u1ea3m l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u c\u1ea3 l\u00fac \u0111\u00f3i v\u00e0 sau khi \u0103n. Kh\u00e1c v\u1edbi c\u00e1c thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft kh\u00e1c, Metformin kh\u00f4ng k\u00edch th\u00edch tuy\u1ebfn t\u1ee5y ti\u1ebft insulin, do \u0111\u00f3 nguy c\u01a1 h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft r\u1ea5t th\u1ea5p.<\/p>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a Metformin ch\u1ee7 y\u1ebfu bao g\u1ed3m:<\/p>\n
\n
Gi\u1ea3m s\u1ea3n sinh \u0111\u01b0\u1eddng: Metformin \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t \u0111\u01b0\u1eddng m\u1edbi \u1edf gan, \u0111\u1ed3ng th\u1eddi l\u00e0m gi\u1ea3m s\u1ef1 ph\u00e2n gi\u1ea3i glycogen d\u1ef1 tr\u1eef th\u00e0nh \u0111\u01b0\u1eddng.<\/li>\n
T\u0103ng s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng: Metformin gi\u00fap c\u00e1c t\u1ebf b\u00e0o c\u01a1 s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng hi\u1ec7u qu\u1ea3 h\u01a1n b\u1eb1ng c\u00e1ch t\u0103ng c\u01b0\u1eddng kh\u1ea3 n\u0103ng h\u1ea5p thu glucose.<\/li>\n
Gi\u1ea3m h\u1ea5p thu \u0111\u01b0\u1eddng: Thu\u1ed1c l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh h\u1ea5p thu \u0111\u01b0\u1eddng t\u1eeb ru\u1ed9t v\u00e0o m\u00e1u.<\/li>\n<\/ul>\n
Ngo\u00e0i t\u00e1c d\u1ee5ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, Metformin c\u00f2n c\u1ea3i thi\u1ec7n t\u00ecnh tr\u1ea1ng r\u1ed1i lo\u1ea1n lipid m\u00e1u, th\u1ec3 hi\u1ec7n qua vi\u1ec7c l\u00e0m gi\u1ea3m cholesterol to\u00e0n ph\u1ea7n, LDL-cholesterol (cholesterol x\u1ea5u) v\u00e0 triglyceride. C\u00e1c nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng \u0111\u00e3 kh\u1eb3ng \u0111\u1ecbnh t\u00e1c d\u1ee5ng c\u00f3 l\u1ee3i n\u00e0y c\u1ee7a Metformin.<\/p>\n
\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n\n\n\n\n\n\n\n\n\n
D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/strong><\/td>\n Linagliptin<\/strong><\/td>\n Metformin hydrochloride<\/strong><\/td>\n<\/tr>\n
H\u1ea5p thu<\/td>\n Nhanh, sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i kho\u1ea3ng 30%; Tmax: 1,5h<\/td>\n Kh\u00f4ng ho\u00e0n to\u00e0n, sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i kho\u1ea3ng 50-60%; Tmax: 2,5h<\/td>\n<\/tr>\n
Ph\u00e2n b\u1ed1<\/td>\n Ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i, li\u00ean k\u1ebft protein cao<\/td>\n Li\u00ean k\u1ebft protein th\u1ea5p, ph\u00e2n b\u1ed1 v\u00e0o h\u1ed3ng c\u1ea7u<\/td>\n<\/tr>\n
Chuy\u1ec3n h\u00f3a<\/td>\n Chuy\u1ec3n h\u00f3a \u00edt, ch\u1ee7 y\u1ebfu th\u1ea3i tr\u1eeb nguy\u00ean d\u1ea1ng<\/td>\n Kh\u00f4ng chuy\u1ec3n h\u00f3a<\/td>\n<\/tr>\n
Th\u1ea3i tr\u1eeb<\/td>\n Qua ph\u00e2n (80%), th\u1eadn (5%); T1\/2 d\u00e0i (>100 gi\u1edd)<\/td>\n Th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua th\u1eadn. Th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 6.5 gi\u1edd.<\/td>\n<\/tr>\n
\u1ea2nh h\u01b0\u1edfng c\u1ee7a th\u1ee9c \u0103n<\/td>\n \u00cdt \u1ea3nh h\u01b0\u1edfng<\/td>\n L\u00e0m gi\u1ea3m v\u00e0 ch\u1eadm h\u1ea5p thu<\/td>\n<\/tr>\n
\u1ea2nh h\u01b0\u1edfng c\u1ee7a b\u1ec7nh l\u00fd<\/td>\n Suy th\u1eadn: T\u0103ng n\u1ed3ng \u0111\u1ed9 \u1edf suy th\u1eadn trung b\u00ecnh v\u00e0 n\u1eb7ng<\/p>\n
Suy gan: Kh\u00f4ng \u1ea3nh h\u01b0\u1edfng<\/td>\n
Suy th\u1eadn: T\u0103ng n\u1ed3ng \u0111\u1ed9 khi suy th\u1eadn<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/500mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/500mg \u0111\u01b0\u1ee3c ph\u1ed1i h\u1ee3p \u0111\u1ec3 n\u00e2ng cao hi\u1ec7u qu\u1ea3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft \u1edf nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng type 2, \u0111\u1eb7c bi\u1ec7t l\u00e0 nh\u1eefng tr\u01b0\u1eddng h\u1ee3p \u0111\u00e3 \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Metformin v\u00e0 Linagliptin ri\u00eang l\u1ebb nh\u01b0ng ch\u01b0a \u0111\u1ea1t \u0111\u01b0\u1ee3c k\u1ebft qu\u1ea3 mong mu\u1ed1n.<\/p>\n
Ngo\u00e0i ra, Trajenta Duo 2,5mg\/500mg c\u00f2n \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh k\u1ebft h\u1ee3p v\u1edbi Sulfonylurea v\u00e0 Metformin \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n ch\u01b0a ki\u1ec3m so\u00e1t t\u1ed1t \u0111\u01b0\u1eddng huy\u1ebft v\u1edbi ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb n\u00e0y.<\/p>\n
Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Trajenta Duo 2,5mg\/500mg 14 vieen<\/h2>\n\n\n\n\n\n\n\n\n\n\n
\u0110\u1ed1i t\u01b0\u1ee3ng<\/td>\n Li\u1ec1u kh\u1edfi \u0111\u1ea7u<\/td>\n Li\u1ec1u t\u1ed1i \u0111a<\/td>\n \u0110i\u1ec1u ch\u1ec9nh li\u1ec1u<\/td>\n<\/tr>\n
Ng\u01b0\u1eddi m\u1edbi d\u00f9ng Metformin<\/td>\n 2,5mg\/500mg x 2 l\u1ea7n\/ng\u00e0y<\/td>\n 5mg Linagliptin\/ 2000mg Metformin<\/td>\n T\u0103ng d\u1ea7n li\u1ec1u Metformin n\u1ebfu dung n\u1ea1p t\u1ed1t<\/td>\n<\/tr>\n
Ng\u01b0\u1eddi \u0111\u00e3 d\u00f9ng Metformin \u0111\u01a1n \u0111\u1ed9c<\/td>\n 2,5mg Linagliptin x 2 l\u1ea7n\/ng\u00e0y + li\u1ec1u Metformin \u0111ang d\u00f9ng<\/td>\n 5mg Linagliptin\/ 2000mg Metformin<\/td>\n \u0110i\u1ec1u ch\u1ec9nh li\u1ec1u Metformin n\u1ebfu c\u1ea7n<\/td>\n<\/tr>\n
Ng\u01b0\u1eddi chuy\u1ec3n t\u1eeb ph\u1ed1i h\u1ee3p Metformin v\u00e0 Linagliptin ri\u00eang r\u1ebd<\/td>\n Li\u1ec1u Linagliptin v\u00e0 Metformin \u0111ang d\u00f9ng<\/td>\n 5mg Linagliptin\/ 2000mg Metformin<\/td>\n \u0110i\u1ec1u ch\u1ec9nh li\u1ec1u n\u1ebfu c\u1ea7n<\/td>\n<\/tr>\n
Ng\u01b0\u1eddi ph\u1ed1i h\u1ee3p Metformin v\u00e0 Sulfonylurea<\/td>\n 2,5mg Linagliptin x 2 l\u1ea7n\/ng\u00e0y + li\u1ec1u Metformin \u0111ang d\u00f9ng<\/td>\n 5mg Linagliptin\/ 2000mg Metformin<\/td>\n C\u00f3 th\u1ec3 gi\u1ea3m li\u1ec1u Sulfonylurea<\/td>\n<\/tr>\n
Ng\u01b0\u1eddi cao tu\u1ed5i<\/td>\n Gi\u1ed1ng nh\u01b0 ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh<\/td>\n 5mg Linagliptin\/ 2000mg Metformin<\/td>\n Theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn th\u01b0\u1eddng xuy\u00ean<\/td>\n<\/tr>\n
Suy th\u1eadn<\/td>\n Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh n\u1ebfu eGFR < 30ml\/ph\u00fat\/1.73m2<\/td>\n –<\/td>\n Kh\u00f4ng khuy\u1ebfn c\u00e1o kh\u1edfi \u0111\u1ea7u n\u1ebfu eGFR 30-45ml\/ph\u00fat\/1.73m2<\/p>\n
Ng\u1eebng thu\u1ed1c n\u1ebfu eGFR gi\u1ea3m d\u01b0\u1edbi 30ml\/ph\u00fat\/1.73m2<\/td>\n<\/tr>\n
Suy gan<\/td>\n Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh<\/td>\n –<\/td>\n –<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Trajenta Duo 2,5mg\/500mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n
Kh\u00f4ng s\u1eed d\u1ee5ng Trajenta Duo trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n
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C\u00e1c tr\u01b0\u1eddng h\u1ee3p c\u1ea5p t\u00ednh c\u00f3 th\u1ec3 l\u00e0m suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn.<\/li>\n
Ng\u1ed9 \u0111\u1ed9c r\u01b0\u1ee3u c\u1ea5p t\u00ednh<\/li>\n
Qu\u00e1 m\u1eabn v\u1edbi Metformin ho\u1eb7c Linagliptin<\/li>\n
Suy gan<\/li>\n
Suy tim m\u1ea5t b\u00f9<\/li>\n
Suy th\u1eadn n\u1eb7ng (eGFR d\u01b0\u1edbi 30 ml\/ph\u00fat\/1,73m2)<\/li>\n
Toan chuy\u1ec3n h\u00f3a c\u1ea5p t\u00ednh ho\u1eb7c m\u00e3n t\u00ednh, bao g\u1ed3m c\u1ea3 nhi\u1ec5m toan ceton do ti\u1ec3u \u0111\u01b0\u1eddng<\/li>\n
Ti\u1ec1n h\u00f4n m\u00ea do ti\u1ec3u \u0111\u01b0\u1eddng<\/li>\n<\/ul>\n
$\"Thu\u1ed1c$
Thu\u1ed1c Trajenta Duo 2,5mg\/500mg d\u00f9ng cho \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0o?<\/figcaption><\/figure>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Trajenta Duo 2,5mg\/500mg<\/h2>\n
Th\u1eadn tr\u1ecdng<\/h3>\n
Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh thu\u1ed1c Trajenta Duo 2,5mg\/500mg \u1edf nh\u1eefng ng\u01b0\u1eddi b\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng type 1 ho\u1eb7c \u0111ang trong t\u00ecnh tr\u1ea1ng acid h\u00f3a m\u00e1u.<\/p>\n
K\u1ebft h\u1ee3p Trajenta Duo 2,5mg\/500mg v\u1edbi c\u00e1c thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft kh\u00e1c c\u00f3 th\u1ec3 t\u0103ng nguy c\u01a1 h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi cao tu\u1ed5i, suy nh\u01b0\u1ee3c ho\u1eb7c suy dinh d\u01b0\u1ee1ng.<\/p>\n
Nguy c\u01a1 nhi\u1ec5m toan lactic t\u0103ng cao \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 suy th\u1eadn, s\u1eed d\u1ee5ng thu\u1ed1c c\u1ea3n quang, u\u1ed1ng nhi\u1ec1u r\u01b0\u1ee3u, suy gan, tr\u00ean 65 tu\u1ed5i. Bi\u1ec3u hi\u1ec7n: m\u1ec7t m\u1ecfi, \u0111au c\u01a1, kh\u00f3 th\u1edf. X\u1eed tr\u00ed: Ng\u1eebng thu\u1ed1c, \u0111\u1ebfn b\u1ec7nh vi\u1ec7n, l\u1ecdc m\u00e1u.<\/p>\n
Ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c Trajenta Duo 2,5mg\/500mg ngay l\u1eadp t\u1ee9c n\u1ebfu xu\u1ea5t hi\u1ec7n c\u00e1c d\u1ea5u hi\u1ec7u d\u1ecb \u1ee9ng nh\u01b0 ph\u00e1t ban, ng\u1ee9a, s\u01b0ng m\u1eb7t ho\u1eb7c kh\u00f3 th\u1edf.<\/p>\n
Vitamin B12: Metformin c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m h\u1ea5p thu vitamin B12. Theo d\u00f5i \u0111\u1ecbnh k\u1ef3.<\/p>\n
Ch\u1ee9c n\u0103ng tim: Theo d\u00f5i ch\u1eb7t ch\u1ebd \u1edf b\u1ec7nh nh\u00e2n suy tim. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf suy tim c\u1ea5p ho\u1eb7c kh\u00f4ng \u1ed5n \u0111\u1ecbnh.<\/p>\n
B\u1ecdng n\u01b0\u1edbc pemphigoid: C\u00f3 th\u1ec3 x\u1ea3y ra. Ng\u1eebng thu\u1ed1c n\u1ebfu nghi ng\u1edd.<\/p>\n
T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n<\/h3>\n\n\n\n\n\n\n\n\n\n\n
C\u01a1 quan<\/td>\n T\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn<\/td>\n T\u00e1c d\u1ee5ng ph\u1ee5 kh\u00e1c<\/td>\n<\/tr>\n
Da<\/td>\n Ng\u1ee9a<\/td>\n Ph\u00f9 m\u1ea1ch, m\u00e0y \u0111ay, ph\u00e1t ban<\/td>\n<\/tr>\n
\u0110\u01b0\u1eddng huy\u1ebft<\/td>\n H\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft (khi ph\u1ed1i h\u1ee3p v\u1edbi Sulfonylurea ho\u1eb7c insulin)<\/td>\n <\/td>\n<\/tr>\n
Gan<\/td>\n <\/td>\n B\u1ea5t th\u01b0\u1eddng x\u00e9t nghi\u1ec7m ch\u1ee9c n\u0103ng gan, vi\u00eam gan (khi d\u00f9ng Metformin)<\/td>\n<\/tr>\n
H\u00f4 h\u1ea5p<\/td>\n Vi\u00eam m\u0169i h\u1ecdng, ho<\/td>\n <\/td>\n<\/tr>\n
Huy\u1ebft h\u1ecdc<\/td>\n <\/td>\n Gi\u1ea3m h\u1ea5p thu vitamin B12 (khi d\u00f9ng l\u00e2u d\u00e0i Metformin)<\/td>\n<\/tr>\n
Ti\u00eau h\u00f3a<\/td>\n Ti\u00eau ch\u1ea3y, bu\u1ed3n n\u00f4n, n\u00f4n, gi\u1ea3m c\u1ea3m gi\u00e1c th\u00e8m \u0103n, \u0111au b\u1ee5ng, vi\u00eam t\u1ee5y<\/td>\n <\/td>\n<\/tr>\n
To\u00e0n th\u00e2n<\/td>\n <\/td>\n Qu\u00e1 m\u1eabn<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h3>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
T\u01b0\u01a1ng t\u00e1c<\/td>\n Linagliptin<\/td>\n Metformin<\/td>\n<\/tr>\n
CYP450<\/td>\n \u1ee8c ch\u1ebf y\u1ebfu CYP3A4, kh\u00f4ng g\u00e2y c\u1ea3m \u1ee9ng CYP<\/td>\n <\/td>\n<\/tr>\n
Digoxin, Warfarin<\/td>\n Kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u00e1c thu\u1ed1c n\u00e0y<\/td>\n <\/td>\n<\/tr>\n
OCT<\/td>\n Kh\u00f4ng ph\u1ea3i l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf OCT<\/td>\n L\u00e0 c\u01a1 ch\u1ea5t c\u1ee7a OCT, c\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c s\u1eed d\u1ee5ng chung \u0111\u01b0\u1eddng v\u1eadn chuy\u1ec3n n\u00e0y<\/td>\n<\/tr>\n
P-glycoprotein<\/td>\n L\u00e0 c\u01a1 ch\u1ea5t v\u00e0 \u1ee9c ch\u1ebf y\u1ebfu P-glycoprotein<\/td>\n <\/td>\n<\/tr>\n
Rifampicin<\/td>\n Gi\u1ea3m n\u1ed3ng \u0111\u1ed9 Linagliptin<\/td>\n <\/td>\n<\/tr>\n
Ritonavir<\/td>\n T\u0103ng n\u1ed3ng \u0111\u1ed9 Linagliptin nh\u01b0ng kh\u00f4ng c\u00f3 \u00fd ngh\u0129a l\u00e2m s\u00e0ng<\/td>\n <\/td>\n<\/tr>\n
R\u01b0\u1ee3u<\/td>\n <\/td>\n T\u0103ng nguy c\u01a1 nhi\u1ec5m toan lactic<\/td>\n<\/tr>\n
Simvastatin<\/td>\n T\u0103ng nh\u1eb9 n\u1ed3ng \u0111\u1ed9 Simvastatin<\/td>\n <\/td>\n<\/tr>\n
Sulfonylurea<\/td>\n Kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a Glibenclamide<\/td>\n <\/td>\n<\/tr>\n
Thiazolidinedione<\/td>\n Kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a Pioglitazone<\/td>\n <\/td>\n<\/tr>\n
Thu\u1ed1c c\u1ea3n quang<\/td>\n <\/td>\n T\u0103ng nguy c\u01a1 suy th\u1eadn c\u1ea5p v\u00e0 nhi\u1ec5m toan lactic<\/td>\n<\/tr>\n
Tr\u00e1nh thai \u0111\u01b0\u1eddng u\u1ed1ng<\/td>\n Kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a thu\u1ed1c tr\u00e1nh thai \u0111\u01b0\u1eddng u\u1ed1ng.<\/td>\n <\/td>\n<\/tr>\n
\u1ee8c ch\u1ebf carbonic anhydrase<\/td>\n <\/td>\n T\u0103ng nguy c\u01a1 nhi\u1ec5m toan lactic<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 ph\u1ee5 n\u1eef cho con b\u00fa<\/h3>\n
Ch\u01b0a c\u00f3 \u0111\u1ee7 b\u1eb1ng ch\u1ee9ng v\u1ec1 \u0111\u1ed9 an to\u00e0n c\u1ee7a Trajenta Duo 2,5mg\/500mg 14 vi\u00ean<\/strong> khi s\u1eed d\u1ee5ng trong thai k\u1ef3. Do \u0111\u00f3, kh\u00f4ng khuy\u1ebfn ngh\u1ecb s\u1eed d\u1ee5ng thu\u1ed1c n\u00e0y cho ph\u1ee5 n\u1eef mang thai.<\/p>\n
C\u1ea3 Metformin v\u00e0 Linagliptin \u0111\u1ec1u c\u00f3 th\u1ec3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9. V\u00ec v\u1eady, \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o an to\u00e0n cho tr\u1ebb s\u01a1 sinh, kh\u00f4ng n\u00ean cho con b\u00fa khi \u0111ang s\u1eed d\u1ee5ng Trajenta Duo 2,5mg\/500mg.<\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n
Li\u1ec1u \u0111\u01a1n Linagliptin l\u00ean \u0111\u1ebfn 600mg (g\u1ea5p 120 l\u1ea7n li\u1ec1u th\u00f4ng th\u01b0\u1eddng) v\u1eabn an to\u00e0n. M\u1eb7c d\u00f9 li\u1ec1u cao Metformin c\u00f3 th\u1ec3 g\u00e2y nhi\u1ec5m toan lactic, m\u1ed9t c\u1ea5p c\u1ee9u y t\u1ebf, nh\u01b0ng ch\u01b0a c\u00f3 b\u00e1o c\u00e1o v\u1ec1 tr\u01b0\u1eddng h\u1ee3p t\u1eed vong do qu\u00e1 li\u1ec1u \u0111\u01a1n thu\u1ea7n. \u0110i\u1ec1u tr\u1ecb bao g\u1ed3m lo\u1ea1i b\u1ecf thu\u1ed1c ch\u01b0a h\u1ea5p th\u1ee5 v\u00e0 l\u1ecdc th\u1eadn.<\/p>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/500mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/500mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n
Tr\u01b0\u1eddng h\u1ee3p thu\u1ed1c Trajenta Duo 2,5mg\/500mg t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi thu\u1ed1c Trajenta Duo 2,5mg\/500mg nh\u01b0:<\/p>\n
Thu\u1ed1c Glyxambi 25mg\/5mg<\/a> (Boehringer Ingelheim Pharma GmbH & Co. KG, c\u00f3 gi\u00e1 t\u1eeb 1.300.000-1.500.000\u0111\/h\u1ed9p), ch\u1ee9a Empagliflozin 25mg (\u1ee9c ch\u1ebf SGLT2, t\u0103ng \u0111\u00e0o th\u1ea3i glucose qua n\u01b0\u1edbc ti\u1ec3u, h\u1ed7 tr\u1ee3 gi\u1ea3m c\u00e2n v\u00e0 huy\u1ebft \u00e1p) v\u00e0 Linagliptin 5mg (\u1ee9c ch\u1ebf DPP-4, t\u0103ng ti\u1ebft insulin, gi\u1ea3m glucagon), \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng t\u00fdp 2 cho ng\u01b0\u1eddi tr\u00ean 18 tu\u1ed5i.<\/p>\n
Thu\u1ed1c Trajenta Duo 2,5mg\/1000mg<\/strong><\/a> (Boehringer Ingelheim Pharma GmbH & Co. KG, c\u00f3 gi\u00e1 kho\u1ea3ng 300.000\u0111\/h\u1ed9p), ch\u1ee9a Linagliptin 2,5mg (\u1ee9c ch\u1ebf DPP-4, b\u1ea3o v\u1ec7 hormone incretin, t\u0103ng ti\u1ebft insulin, gi\u1ea3m s\u1ea3n xu\u1ea5t glucose) v\u00e0 Metformin hydrochloride 1000mg (gi\u1ea3m s\u1ea3n xu\u1ea5t glucose \u1edf gan, t\u0103ng s\u1eed d\u1ee5ng glucose, l\u00e0m ch\u1eadm h\u1ea5p thu glucose), \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng type 2 khi \u0111\u01a1n tr\u1ecb li\u1ec7u ho\u1eb7c c\u00e1c ph\u01b0\u01a1ng ph\u00e1p kh\u00e1c kh\u00f4ng \u0111\u1ee7 hi\u1ec7u qu\u1ea3.<\/p>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n\n
S A Ross 1, A E Caballero, S Del Prato, B Gallwitz, D Lewis-D’Agostino, Z Bailes, S Thiemann, S Patel, H-J Woerle, M von Eynatten. (Ng\u00e0y 19 th\u00e1ng 11 n\u0103m 2014). Initial combination of linagliptin and metformin compared with linagliptin monotherapy in patients with newly diagnosed type 2 diabetes and marked hyperglycaemia: a randomized, double-blind, active-controlled, parallel group, multinational clinical trial<\/em>. Truy c\u1eadp ng\u00e0y 20 th\u00e1ng 12 n\u0103m 2024, t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/25298165\/<\/a><\/li>\n
M-R Taskinen 1, J Rosenstock, I Tamminen, R Kubiak, S Patel, K A Dugi, H-J Woerle. (Th\u00e1ng 1 n\u0103m 2011). Safety and efficacy of linagliptin as add-on therapy to metformin in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled study<\/em>. Truy c\u1eadp ng\u00e0y 20 th\u00e1ng 12 n\u0103m 2024, t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/21114605\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"
Thu\u1ed1c Trajenta Duo 2.5mg\/500mg l\u00e0 thu\u1ed1c k\u1ebft h\u1ee3p hai ho\u1ea1t ch\u1ea5t Linagliptin v\u00e0 Metformin, gi\u00fap gi\u1ea3m l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u, t\u0103ng c\u01b0\u1eddng kh\u1ea3 n\u0103ng s\u1eed d\u1ee5ng insulin c\u1ee7a c\u01a1 th\u1ec3 v\u00e0 gi\u1ea3m s\u1ea3n xu\u1ea5t \u0111\u01b0\u1eddng \u1edf gan \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng type 2<\/p>\n","protected":false},"author":1,"featured_media":107340,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-107338","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/107338","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=107338"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/107340"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=107338"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=107338"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=107338"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

Tr\u00ecnh b\u00e0y<\/h3>\nS\u0110K: 750110167200<\/p>\nQuy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd 14 vi\u00ean<\/p>\nXu\u1ea5t x\u1ee9: Mexico<\/p>\n

T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Trajenta Duo 2,5mg\/500mg<\/h2>\n

L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Trajenta Duo 2,5mg\/500mg<\/h2>\n

Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: 750110167200<\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd 14 vi\u00ean<\/p>\n
Xu\u1ea5t x\u1ee9: Mexico<\/p>\n