{"id":101354,"date":"2024-09-28T12:41:19","date_gmt":"2024-09-28T05:41:19","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=101354"},"modified":"2025-07-24T13:23:00","modified_gmt":"2025-07-24T06:23:00","slug":"ricovir-em-200mg-300mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/ricovir-em-200mg-300mg\/","title":{"rendered":"Ricovir-EM 200mg\/300mg"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, <\/b>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/b><\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Ricovir-EM 200mg\/300mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Mylan Laboratories Limited, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-16946-13.<\/b><\/p>\n

Ricovir-EM 200mg\/300mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n

Th\u00e0nh ph\u1ea7n<\/h3>\n

M\u1ed7i vi\u00ean u\u1ed1ng Ricovir-EM 200mg\/300mg<\/b> g\u1ed3m c\u00f3:<\/p>\n\n\n\n\n\n\n
Ho\u1ea1t ch\u1ea5t<\/td>\nH\u00e0m l\u01b0\u1ee3ng<\/td>\n<\/tr>\n
Emtricitabine<\/td>\n200mg<\/td>\n<\/tr>\n
Tenofovir disoproxil fumarate<\/td>\n300mg<\/td>\n<\/tr>\n
T\u00e1 d\u01b0\u1ee3c<\/td>\nV\u1eeba \u0111\u1ee7<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim.<\/p>\n

Tr\u00ecnh b\u00e0y<\/h3>\n

S\u0110K: VN-16946-13.<\/p>\n

Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 chai 30 vi\u00ean.<\/p>\n

Xu\u1ea5t x\u1ee9: \u1ea4n \u0110\u1ed9.<\/p>\n

C\u00f4ng d\u1ee5ng c\u1ee7a thu\u1ed1c Ricovir-EM 200mg\/300mg<\/h2>\n

C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n

Emtricitabine l\u00e0 m\u1ed9t \u0111\u1ed3ng \u0111\u1eb3ng nucleoside v\u00e0 \u0111\u01b0\u1ee3c n\u1eb1m trong nh\u00f3m cytidine. C\u00f2n Tenofovir disoproxil fumarate khi v\u00e0o c\u01a1 th\u1ec3 s\u1ebd \u0111\u01b0\u1ee3c chuy\u1ec3n th\u00e0nh d\u1ea1ng Tenofovir. Hai thu\u1ed1c Tenofovir v\u00e0 Emtricitabine \u0111\u1ec1u l\u00e0 nh\u1eefng ch\u1ea5t c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1eb7c hi\u1ec7u \u1edf c\u00e1c virus l\u00e0m suy gi\u1ea3m mi\u1ec5n d\u1ecbch tr\u00ean ng\u01b0\u1eddi v\u00e0 virus g\u00e2y b\u1ec7nh vi\u00eam gan B.<\/p>\n

D\u01b0\u1edbi \u1ea3nh h\u01b0\u1edfng c\u1ee7a nh\u1eefng enzyme trong t\u1ebf b\u00e0o, hai thu\u1ed1c s\u1ebd \u0111\u01b0\u1ee3c phosphoryl h\u00f3a \u0111\u1ec3 t\u1ea1o ra Tenofovir diphosphat v\u00e0 Emtricitabine triphosphat. C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a ph\u00e1t huy hi\u1ec7u qu\u1ea3 \u1ee9c ch\u1ebf c\u1ea1nh tranh v\u1edbi men sao ch\u00e9p ng\u01b0\u1ee3c HIV-1 v\u00e0 khi\u1ebfn chu\u1ed7i ADN k\u1ebft th\u00fac.<\/p>\n

\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n

H\u1ea5p thu: Hai ho\u1ea1t ch\u1ea5t \u1edf trong vi\u00ean Ricovir-EM \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh, trong \u0111\u00f3 Tenofovir disoproxil fumarate s\u1ebd \u0111\u01b0\u1ee3c chuy\u1ec3n sang d\u1ea1ng Tenofovir. N\u1ed3ng \u0111\u1ed9 Cmax c\u1ee7a c\u1ea3 hai ch\u1ea5t \u0111\u1ec1u \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 0,5-3 ti\u1ebfng s\u1eed d\u1ee5ng. \u0110\u1ec3 t\u1ed1i \u01b0u h\u1ea5p thu, n\u00ean d\u00f9ng thu\u1ed1c v\u00e0o l\u00fac \u0103n.<\/p>\n

Ph\u00e2n b\u1ed1: Vd c\u1ee7a Tenofovir v\u00e0 Emtricitabine sau khi truy\u1ec1n t\u0129nh m\u1ea1ch l\u1ea7n l\u01b0\u1ee3t \u0111\u1ea1t 1,4l\/kg v\u00e0 800ml\/kg. Hai thu\u1ed1c \u0111\u01b0\u1ee3c ph\u00e2n b\u1ed1 kh\u1eafp n\u01a1i c\u1ee7a c\u01a1 th\u1ec3. Trong \u0111\u00f3 l\u01b0\u1ee3ng Emtricitabine g\u1eafn v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng ch\u1ec9 d\u01b0\u1edbi 4%, c\u00f2n Tenofovir g\u1eafn l\u00ean protein huy\u1ebft t\u01b0\u01a1ng hay huy\u1ebft thanh kho\u1ea3ng 0,7 v\u00e0 7,2% li\u1ec1u.<\/p>\n

Chuy\u1ec3n h\u00f3a: Emtricitabine \u0111\u01b0\u1ee3c oxy h\u00f3a nh\u00f3m Thiol ho\u1eb7c g\u1eafn k\u1ebft v\u1edbi Acid Glucuronic.<\/p>\n

\u0110\u00e0o th\u1ea3i: Emtricitabine \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb ch\u00ednh b\u1edfi th\u1eadn, trong \u0111\u00f3 c\u00f3 86% l\u01b0\u1ee3ng qua n\u01b0\u1edbc ti\u1ec3u, c\u00f2n 14% qua ph\u00e2n. T\u1ea1i n\u01b0\u1edbc ti\u1ec3u, c\u00f3 13% thu\u1ed1c \u0111ang \u1edf d\u1ea1ng chuy\u1ec3n h\u00f3a. Ngo\u00e0i ra \u0111\u1ed9 thanh th\u1ea3i c\u1ee7a Emtricitabine kho\u1ea3ng 307ml\/ph\u00fat, c\u00f2n th\u1eddi gian b\u00e1n h\u1ee7y l\u00e0 10 ti\u1ebfng. Tenofovir c\u0169ng \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i ch\u1ee7 y\u1ebfu nh\u1edd th\u1eadn, khi \u0111\u00e0o th\u1ea3i ch\u1ee7 y\u1ebfu \u1edf d\u1ea1ng ban \u0111\u1ea7u. Th\u1eddi gian b\u00e1n h\u1ee7y c\u1ee7a Tenofovir d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng kho\u1ea3ng 12-18 ti\u1ebfng, \u0111\u1ed9 thanh th\u1ea3i th\u1eadn kho\u1ea3ng 210ml\/ph\u00fat.<\/p>\n

Thu\u1ed1c Ricovir-EM 200mg\/300mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n

Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c ch\u1ea5t kh\u00e1ng retrovirus v\u00e0 nh\u1eefng ch\u1ea5t kh\u00e1ng virus kh\u00e1c theo ch\u1ec9 d\u1eabn c\u1ee7a B\u1ed9 Y t\u1ebf nh\u1eb1m tr\u1ecb HIV-1.<\/p>\n

\"Thu\u1ed1c<\/a>
Thu\u1ed1c Ricovir-EM 200mg\/300mg \u0111i\u1ec1u tr\u1ecb HIV<\/figcaption><\/figure>\n

C\u00e1ch d\u00f9ng v\u00e0 li\u1ec1u d\u00f9ng Ricovir-EM 200mg\/300mg<\/h2>\n

Li\u1ec1u d\u00f9ng<\/h3>\n

Ng\u01b0\u1eddi l\u1edbn: D\u00f9ng 1 vi\u00ean m\u1ed7i ng\u00e0y v\u00e0 n\u00ean u\u1ed1ng v\u00e0o b\u1eefa \u0103n.<\/p>\n

Tr\u1ebb em: Kh\u00f4ng n\u00ean d\u00f9ng Ricovir-EM cho nh\u1eefng tr\u1ebb d\u01b0\u1edbi 18 tu\u1ed5i.<\/p>\n

Ng\u01b0\u1eddi l\u1edbn tu\u1ed5i: Kh\u00f4ng nh\u1ea5t thi\u1ebft ph\u1ea3i hi\u1ec7u ch\u1ec9nh li\u1ec1u, tr\u1eeb khi b\u1ec7nh nh\u00e2n m\u1eafc suy th\u1eadn.<\/p>\n

Ng\u01b0\u1eddi b\u1ec7nh c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn suy gi\u1ea3m: N\u1ebfu b\u1ecb suy th\u1eadn nh\u1eb9 kh\u00f4ng ph\u1ea3i ch\u1ec9nh l\u1ea1i li\u1ec1u. Suy th\u1eadn n\u1eb7ng kh\u00f4ng d\u00f9ng. Suy th\u1eadn v\u1eeba n\u00ean hi\u1ec7u ch\u1ec9nh kho\u1ea3ng c\u00e1ch c\u00e1c li\u1ec1u d\u00f9ng nh\u01b0 b\u1ea3ng sau:<\/p>\n\n\n\n\n\n
<\/td>\n\u0110\u1ed9 thanh th\u1ea3i creatinin (ml\/ph\u00fat)<\/td>\n<\/tr>\n
50-80<\/td>\n30-49<\/td>\n<\/tr>\n
Kho\u1ea3ng c\u00e1ch gi\u1eefa 2 l\u1ea7n d\u00f9ng<\/td>\n24 gi\u1edd<\/td>\n48 gi\u1edd<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Kh\u00f4ng ph\u1ea3i \u0111i\u1ec1u ch\u1ec9nh l\u1ea1i li\u1ec1u tr\u00ean ng\u01b0\u1eddi suy gan.<\/p>\n

C\u00e1ch d\u00f9ng<\/h3>\n

U\u1ed1ng vi\u00ean v\u1edbi n\u01b0\u1edbc. N\u1ebfu g\u1eb7p ch\u1ee9ng kh\u00f3 nu\u1ed1t, c\u00f3 th\u1ec3 ph\u00e2n t\u00e1n vi\u00ean trong n\u01b0\u1edbc l\u1ecdc, n\u01b0\u1edbc cam hay nho r\u1ed3i s\u1eed d\u1ee5ng.<\/p>\n

Kh\u00f4ng s\u1eed d\u1ee5ng Ricovir-EM 200mg\/300mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n

Nh\u1eefng ng\u01b0\u1eddi qu\u00e1 m\u1eabn v\u1edbi th\u00e0nh ph\u1ea7n c\u1ee7a Ricovir-EM.<\/p>\n

L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Ricovir-EM 200mg\/300mg<\/h2>\n

Th\u1eadn tr\u1ecdng<\/h3>\n

Kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng v\u1edbi nh\u1eefng ch\u1ebf ph\u1ea9m kh\u00e1c \u0111ang ch\u1ee9a \u0111\u1ed3ng \u0111\u1eb3ng cytidine ho\u1eb7c c\u0169ng \u0111ang c\u00f3 Emtricitabine v\u00e0 Tenofovir.<\/p>\n

Ng\u01b0\u1eddi \u0111ang d\u00f9ng vi\u00ean k\u1ebft h\u1ee3p ho\u1eb7c nh\u1eefng ch\u1ea5t kh\u00e1ng retrovirus v\u1eabn c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3i nhi\u1ec5m tr\u00f9ng c\u01a1 h\u1ed9i ho\u1eb7c c\u00e1c bi\u1ebfn ch\u1ee9ng th\u01b0\u1eddng th\u1ea5y \u1edf b\u1ec7nh HIV. Do \u0111\u00f3 c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y v\u1eabn c\u1ea7n \u0111\u01b0\u1ee3c b\u00e1c s\u0129 theo d\u00f5i ch\u1eb7t ch\u1ebd.<\/p>\n

Thu\u1ed1c kh\u00f4ng gi\u00fap ng\u0103n ch\u1eb7n l\u00e2y nhi\u1ec5m HIV sang ng\u01b0\u1eddi kh\u00e1c qua truy\u1ec1n m\u00e1u hay quan h\u1ec7 t\u00ecnh d\u1ee5c. Do \u0111\u00f3 ng\u01b0\u1eddi m\u1eafc HIV v\u1eabn c\u1ea7n d\u00f9ng c\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba ph\u00f9 h\u1ee3p.<\/p>\n

Ng\u01b0\u1eddi b\u1ecb b\u1ea5t dung n\u1ea1p Lactose c\u1ea7n ch\u00fa \u00fd do vi\u00ean ch\u1ee9a t\u00e1 d\u01b0\u1ee3c n\u00e0y.<\/p>\n

Gi\u00e1m s\u00e1t ch\u1eb7t ch\u1ebd k\u00e8m theo \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u cho nh\u1eefng ng\u01b0\u1eddi suy th\u1eadn nh\u1eb9, v\u1eeba. Kh\u00f4ng d\u00f9ng n\u1ebfu ch\u1ee9c n\u0103ng th\u1eadn b\u1ecb suy gi\u1ea3m n\u1eb7ng.<\/p>\n

Tr\u00e1nh d\u00f9ng Ricovir-EM ph\u1ed1i h\u1ee3p ch\u1ea5t kh\u00e1ng retrovirus cho nh\u1eefng ng\u01b0\u1eddi b\u1ecb HIV-1 tr\u01b0\u1edbc \u0111\u00f3 c\u00f3 k\u00e8m \u0111\u1ed9t bi\u1ebfn K65R.<\/p>\n

Ng\u01b0\u1eddi b\u1ec7nh b\u1ecb \u0111\u1ed3ng th\u1eddi HBV v\u00e0 HIV c\u1ea7n ph\u1ea3i \u0111\u01b0\u1ee3c gi\u00e1m s\u00e1t trong v\u00e0 sau \u00edt nh\u1ea5t v\u00e0i th\u00e1ng k\u1ec3 t\u1eeb khi ng\u01b0ng d\u00f9ng Ricovir-EM.<\/p>\n

Ng\u01b0\u1eddi b\u1ecb b\u1ec7nh gan n\u1eb7ng n\u00ean c\u00e2n nh\u1eafc v\u1ec1 vi\u1ec7c tr\u1ecb li\u1ec7u ng\u1eaft qu\u00e3ng hay d\u1eebng \u0111i\u1ec1u tr\u1ecb.<\/p>\n

D\u00f9ng c\u1ea9n tr\u1ecdng thu\u1ed1c tr\u00ean ng\u01b0\u1eddi b\u1ecb vi\u00eam gan, ph\u00ec \u0111\u1ea1i gan hay c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1 cao b\u1ecb b\u1ec7nh v\u1ec1 gan.<\/p>\n

Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ra lo\u1ea1n d\u01b0\u1ee1ng m\u1ee1, r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng ty th\u1ec3 tr\u00ean ng\u01b0\u1eddi b\u1ec7nh HIV.<\/p>\n

T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n\n\n\n\n
T\u1ea7n su\u1ea5t<\/td>\nR\u1ea5t th\u01b0\u1eddng g\u1eb7p<\/td>\nHay g\u1eb7p<\/td>\nTh\u01b0\u1eddng g\u1eb7p<\/td>\nHi\u1ebfm g\u1eb7p<\/td>\nR\u1ea5t hi\u1ebfm g\u1eb7p<\/td>\n<\/tr>\n
Ph\u1ea3n \u1ee9ng<\/td>\n\u0110au \u0111\u1ea7u, t\u0103ng CK, ch\u00f3ng m\u1eb7t<\/td>\nSuy nh\u01b0\u1ee3c, \u0111au nh\u1ee9c c\u01a1 th\u1ec3, Da b\u1ecb n\u1ed5i ban m\u1ee7, ng\u1ee9a, m\u1ec1 \u0111ay, t\u0103ng s\u1eafc t\u1ed1. T\u0103ng \u0111\u01b0\u1eddng m\u00e1u, d\u1ecb \u1ee9ng,…<\/td>\nM\u1ea5t ng\u1ee7, m\u01a1 b\u1ea5t th\u01b0\u1eddng<\/td>\nSuy th\u1eadn, t\u0103ng creatinin, vi\u00eam t\u1ee5y, nhi\u1ec5m acid lactic, protein ni\u1ec7u,…<\/td>\nKh\u00f3 th\u1edf, vi\u00eam gan.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

T\u01b0\u01a1ng t\u00e1c<\/h3>\n\n\n\n\n\n\n
Thu\u1ed1c<\/td>\nT\u01b0\u01a1ng t\u00e1c<\/td>\n<\/tr>\n
Didanosine<\/td>\nC\u00f3 th\u1ec3 l\u00e0m t\u0103ng AUC c\u1ee7a Didonasine, do \u0111\u00f3 kh\u00f4ng n\u00ean ph\u1ed1i h\u1ee3p<\/td>\n<\/tr>\n
Atazanavir<\/td>\nC\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m AUC, Cmin c\u1ee7a Atazanavir<\/td>\n<\/tr>\n
Ch\u1ea5t \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft ch\u1ee7 \u0111\u1ed9ng b\u1edfi h\u1ec7 th\u1ed1ng v\u1eadn chuy\u1ec3n anion h\u1eefu c\u01a1<\/td>\nC\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Tenofovir<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

L\u01b0u \u00fd khi d\u00f9ng cho m\u1eb9 mang thai v\u00e0 cho con b\u00fa<\/h3>\n

Ch\u1ec9 n\u00ean d\u00f9ng tr\u00ean ng\u01b0\u1eddi \u0111ang c\u00f3 thai n\u1ebfu kh\u00f4ng c\u00f2n bi\u1ec7n ph\u00e1p kh\u00e1c.<\/p>\n

Ph\u1ee5 n\u1eef kh\u00f4ng n\u00ean cho con b\u00fa s\u1eefa m\u1eb9 n\u1ebfu nh\u01b0 \u0111ang nhi\u1ec5m HIV.<\/p>\n

L\u01b0u \u00fd s\u1eed d\u1ee5ng khi \u0111ang l\u00e1i xe, v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n

Ch\u00fa \u00fd th\u1eadn tr\u1ecdng v\u00ec trong qu\u00e1 tr\u00ecnh d\u00f9ng thu\u1ed1c c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3i tri\u1ec7u ch\u1ee9ng ch\u00f3ng m\u1eb7t.<\/p>\n

Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n

Ph\u1ea3i gi\u00e1m s\u00e1t nh\u1eefng d\u1ea5u hi\u1ec7u ng\u1ed9 \u0111\u1ed9c tr\u00ean ng\u01b0\u1eddi u\u1ed1ng qu\u00e1 li\u1ec1u. \u00c1p d\u1ee5ng li\u1ec7u ph\u00e1p h\u1ed7 tr\u1ee3 ti\u00eau chu\u1ea9n, l\u1ecdc m\u00e1u.<\/p>\n

Thu\u1ed1c Ricovir-EM 200mg\/300mg gi\u00e1 bao nhi\u00eau? mua \u1edf \u0111\u00e2u?<\/h2>\n

Thu\u1ed1c Ricovir-EM 200mg\/300mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Ricovir-EM 200mg\/300mg<\/b> c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadt t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n

K\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<\/p>\n