{"id":7651,"date":"2019-04-15T13:07:43","date_gmt":"2019-04-15T06:07:43","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?p=7651"},"modified":"2019-04-19T13:48:49","modified_gmt":"2019-04-19T06:48:49","slug":"khang-sinh-nhom-quinilon-va-fluoroquinolon-dung-toan-than-va-dang-hit","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/khang-sinh-nhom-quinilon-va-fluoroquinolon-dung-toan-than-va-dang-hit\/","title":{"rendered":"Kh\u00e1ng sinh nh\u00f3m Quinilon v\u00e0 Fluoroquinolon d\u00f9ng to\u00e0n th\u00e2n v\u00e0 d\u1ea1ng h\u00edt"},"content":{"rendered":"

Kh\u00e1ng sinh nh\u00f3m Quinilon v\u00e0 Fluoroquinolon d\u00f9ng to\u00e0n th\u00e2n v\u00e0 d\u1ea1ng h\u00edt: nguy c\u01a1 g\u1eb7p c\u00e1c t\u00e1c d\u1ee5ng b\u1ea5t l\u1ee3i g\u00e2y t\u00e0n t\u1eadt k\u00e9o d\u00e0i, kh\u00f4ng h\u1ed3i ph\u1ee5c v\u00e0 c\u00e1c h\u1ea1n ch\u1ebf trong s\u1eed d\u1ee5ng.<\/h2>\n
$\"fluoroquinolon\"$ <\/p>\n
C\u01a1 quan d\u01b0\u1ee3c ph\u1ea9m ch\u00e2u \u00c2u (EMA) \u0111\u00e3 \u0111\u00e1nh gi\u00e1 l\u1ea1i c\u00e1c kh\u00e1ng sinh nh\u00f3m quinolon v\u00e0 fluoroquinolon v\u00ec c\u00e1c t\u00e1c d\u1ee5ng b\u1ea5t l\u1ee3i nghi\u00eam tr\u1ecdng, k\u00e9o d\u00e0i (nhi\u1ec1u th\u00e1ng ho\u1eb7c nhi\u1ec1u n\u0103m) c\u00f3 th\u1ec3 g\u00e2y t\u00e0n t\u1eadt kh\u00f4ng h\u1ed3i ph\u1ee5c v\u00e0 ch\u1ee7 y\u1ebfu \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn h\u1ec7 th\u1ed1ng c\u01a1 x\u01b0\u01a1ng v\u00e0 h\u1ec7 th\u1ea7n kinh.<\/p>\n
T\u1eeb k\u1ebft qu\u1ea3 c\u1ee7a vi\u1ec7c \u0111\u00e1nh gi\u00e1 n\u00e0y, \u1ee7y ban c\u1ea3nh gi\u00e1c d\u01b0\u1ee3c ph\u1ea9m ch\u00e2u \u00c2u (vi\u1ebft t\u1eaft PRAC) \u0111\u00e3 quy\u1ebft \u0111\u1ecbnh r\u1eb1ng s\u1ef1 c\u00e2n b\u1eb1ng gi\u1eefa l\u1ee3i \u00edch v\u00e0 nguy c\u01a1 c\u1ee7a nh\u00f3m quinolone kh\u00f4ng \u0111\u00e1p \u1ee9ng \u0111\u01b0\u1ee3c y\u00eau c\u1ea7u. S\u1ea3n ph\u1ea9m Apurone (ho\u1ea1t ch\u1ea5t flumequin – thu\u1ed1c quinolon duy nh\u1ea5t l\u01b0u h\u00e0nh t\u1ea1i Ph\u00e1p) s\u1ebd b\u1ecb r\u00fat kh\u1ecfi th\u1ecb tr\u01b0\u1eddng.<\/p>\n
PRAC khuy\u1ebfn c\u00e1o h\u1ea1n ch\u1ebf ch\u1ec9 \u0111\u1ecbnh c\u1ee7a nh\u00f3m fluoroquinolon, ch\u1ec9 \u0111\u01b0\u1ee3c d\u00e0nh ri\u00eang cho m\u1ed9t s\u1ed1 b\u1ec7nh l\u00fd nhi\u1ec5m tr\u00f9ng nghi\u00eam tr\u1ecdng m\u00e0 kh\u00f4ng th\u1ec3 s\u1eed d\u1ee5ng c\u00e1c nh\u00f3m kh\u00e1ng sinh kh\u00e1c.<\/p>\n
V\u00ec v\u1eady kh\u00f4ng n\u00ean k\u00ea \u0111\u01a1n thu\u1ed1c fluoroquinolon cho:<\/p>\n
\n
\u0110i\u1ec1u tr\u1ecb nhi\u1ec5m tr\u00f9ng kh\u00f4ng nghi\u00eam tr\u1ecdng ho\u1eb7c t\u1ef1 ph\u00e1t (v\u00ed d\u1ee5: vi\u00eam h\u1ecdng, vi\u00eam amidan, vi\u00eam ph\u1ebf qu\u1ea3n c\u1ea5p t\u00ednh)<\/li>\n
\u0110i\u1ec1u tr\u1ecb ti\u00eau ch\u1ea3y du l\u1ecbch ho\u1eb7c nhi\u1ec5m tr\u00f9ng t\u00e1i ph\u00e1t \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u d\u01b0\u1edbi.<\/li>\n
\u0110i\u1ec1u tr\u1ecb nhi\u1ec5m tr\u00f9ng kh\u00f4ng do vi khu\u1ea9n (v\u00ed d\u1ee5 vi\u00eam tuy\u1ebfn ti\u1ec1n li\u1ec7t kh\u00f4ng do vi khu\u1ea9n)<\/li>\n<\/ul>\n
– \u0110i\u1ec1u tr\u1ecb nhi\u1ec5m tr\u00f9ng nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh khi s\u1eed d\u1ee5ng kh\u00e1ng sinh kh\u00e1c \u0111\u01b0\u1ee3c coi l\u00e0 kh\u00f4ng ph\u00f9 h\u1ee3p (vi\u00eam b\u00e0ng quang kh\u00f4ng bi\u1ebfn ch\u1ee9ng, \u0111\u1ee3t c\u1ea5p c\u1ee7a vi\u00eam ph\u1ebf qu\u1ea3n m\u00e3n t\u00ednh v\u00e0 b\u1ec7nh ph\u1ed5i t\u1eafc ngh\u1ebdn m\u00e3n t\u00ednh, vi\u00eam m\u0169i h\u1ecdng do vi khu\u1ea9n c\u1ea5p t\u00ednh v\u00e0 vi\u00eam tai gi\u1eefa c\u1ea5p t\u00ednh).<\/p>\n
– \u1ede nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed g\u1eb7p t\u00e1c d\u1ee5ng b\u1ea5t l\u1ee3i v\u1edbi m\u1ed9t kh\u00e1ng sinh nh\u00f3m quinolon ho\u1eb7c fluoroquinolon.<\/p>\n
Nh\u00f3m thu\u1ed1c n\u00e0y c\u1ea7n \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh th\u1eadn tr\u1ecdng v\u1edbi b\u1ec7nh nh\u00e2n cao tu\u1ed5i, b\u1ec7nh nh\u00e2n suy th\u1eadn, b\u1ec7nh nh\u00e2n \u0111\u00e3 gh\u00e9p t\u1ea1ng v\u00e0 nh\u1eefng b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi v\u1edbi corticoid do nguy c\u01a1 vi\u00eam g\u00e2n v\u00e0 \u0111\u1ee9t g\u00e2n g\u00e2y ra b\u1edfi nh\u00f3m fluoroquinolon c\u00f3 th\u1ec3 cao h\u01a1n \u1edf nh\u1eefng \u0111\u1ed1i t\u01b0\u1ee3ng tr\u00ean. Kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng fluoroquinolon \u0111\u1ed3ng th\u1eddi corticosteroid.<\/p>\n
B\u00eanh nh\u1eadn \u0111\u01b0\u1ee3c khuy\u00ean d\u1eebng \u0111i\u1ec1u tr\u1ecb v\u00e0 tham kh\u1ea3o \u00fd ki\u1ebfn b\u00e1c s\u0129 khi xu\u1ea5t hi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 \u0111au c\u01a1, y\u1ebfu c\u01a1 v\u00e0 \u0111au kh\u1edbp ho\u1eb7c s\u01b0ng \u0111au xu\u1ea5t hi\u1ec7n.<\/p>\n
C\u00e1c ho\u1ea1t ch\u1ea5t l\u01b0u h\u00e0nh t\u1ea1i Ph\u00e1p c\u1ee7a nh\u00f3m quinolon v\u00e0 fluoroquinolon l\u00e0: ciprofloxacin, levofloxacin, lomefloxacin, moxifloxacin, norfloxacin, flumequin v\u00e0 ofloxacin.<\/p>\n
Ngu\u1ed3n: https:\/\/ansm.sante.fr\/S-informer\/Informations-de-securite-Lettres-aux-professionnels-de-sante\/Antibiotiques-de-la-famille-des-quinolones-et-fluoroquinolones-administres-par-voie-systemique-ou-inhalee-risque-d-effets-indesirables-invalidants-durables-et-potentiellement-irreversibles-et-restrictions-d-utilisation-Lettre-aux-professionnels-de-sante<\/a><\/p>\n
Ng\u01b0\u1eddi t\u1ed5ng h\u1ee3p: V\u0169 \u0110\u1ee9c Ho\u00e0n – Nguy\u1ec5n Ph\u01b0\u01a1ng Th\u00fay – Trung T\u00e2m C\u1ea3nh Gi\u00e1c D\u01b0\u1ee3c Qu\u1ed1c Gia.<\/p>\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
Kh\u00e1ng sinh nh\u00f3m Quinilon v\u00e0 Fluoroquinolon d\u00f9ng to\u00e0n th\u00e2n v\u00e0 d\u1ea1ng h\u00edt: nguy c\u01a1 g\u1eb7p c\u00e1c t\u00e1c d\u1ee5ng b\u1ea5t l\u1ee3i g\u00e2y t\u00e0n t\u1eadt k\u00e9o d\u00e0i, kh\u00f4ng h\u1ed3i ph\u1ee5c v\u00e0 c\u00e1c h\u1ea1n ch\u1ebf trong s\u1eed d\u1ee5ng. C\u01a1 quan d\u01b0\u1ee3c ph\u1ea9m ch\u00e2u \u00c2u (EMA) \u0111\u00e3 \u0111\u00e1nh gi\u00e1 l\u1ea1i c\u00e1c kh\u00e1ng sinh nh\u00f3m quinolon v\u00e0 fluoroquinolon v\u00ec c\u00e1c […]\n","protected":false},"author":1,"featured_media":7653,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-7651","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/7651","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=7651"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/7651\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/7653"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=7651"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=7651"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=7651"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}