{"id":6862,"date":"2019-04-08T22:39:41","date_gmt":"2019-04-08T15:39:41","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?p=6862"},"modified":"2019-04-25T11:38:10","modified_gmt":"2019-04-25T04:38:10","slug":"nham-lan-ve-loi-ich-cua-statin","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/nham-lan-ve-loi-ich-cua-statin\/","title":{"rendered":"Nh\u1ea7m l\u1eabn v\u1ec1 l\u1ee3i \u00edch c\u1ee7a Statin?"},"content":{"rendered":"<h2>Nh\u1ea7m l\u1eabn v\u1ec1 l\u1ee3i \u00edch c\u1ee7a Statin? Hi\u1ec7p h\u1ed9i Tim m\u1ea1ch M\u1ef9 (AHA) tuy\u00ean b\u1ed1 c\u00e2u tr\u1ea3 l\u1eddi.<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecbch: L\u01b0u Th\u1ee5y L\u1ec7 Mai \u2013 sinh vi\u00ean D\u01b0\u1ee3c \u2013 Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc Y khoa Ph\u1ea1m Ng\u1ecdc Th\u1ea1ch<\/p>\n<p>Ng\u01b0\u1eddi hi\u1ec7u \u0111\u00ednh: Ths.Nguy\u1ec5n Th\u1ecb Thu H\u01b0\u01a1ng- Khoa D\u01b0\u1ee3c \u2013Vi\u1ec7n B\u1ecfng L\u00ea H\u1eefu Tr\u00e1c<\/p>\n<p>Ngu\u1ed3n: Confused about statin benefits? New AHA statement has answers (Loren Bonner).\u00a0<a href=\"https:\/\/www.pharmacytoday.org\/article\/S1042-0991(19)30236-1\/fulltext?fbclid=IwAR2ozim6V7q_vPLuFnD5iSRnPqLZEC2JzeGpGXguieblMKVJ0f7lSrEDsXs\" rel=\"noopener\">Link<\/a><\/p>\n<p><strong>Statins<\/strong> l\u00e0 li\u1ec7u ph\u00e1p hi\u1ec7u qu\u1ea3, chi ph\u00ed th\u1ea5p \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 tim m\u1ea1ch, tuy nhi\u00ean n\u00f3 v\u1eabn l\u00e0 m\u1ed9t trong c\u00e1c lo\u1ea1i thu\u1ed1c g\u00e2y tranh c\u00e3i nh\u1ea5t hi\u1ec7n nay. M\u1ed9t tuy\u00ean b\u1ed1 khoa h\u1ecdc m\u1edbi t\u1eeb Hi\u1ec7p h\u1ed9i Tim m\u1ea1ch M\u1ef9 (AHA) nh\u1eb1m l\u00e0m s\u00e1ng t\u1ecf m\u1ed9t s\u1ed1 nguy c\u01a1 c\u1ee7a statin b\u1eb1ng c\u00e1ch cung c\u1ea5p v\u1edbi c\u00e1c b\u00ean \u00a0l\u00e2m s\u00e0ng m\u1ed9t s\u1ed1 ph\u00e2n t\u00edch d\u1ef1a tr\u00ean b\u1eb1ng ch\u1ee9ng v\u1ec1 c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 c\u00e1c m\u1ed1i quan ng\u1ea1i li\u00ean quan \u0111\u1ebfn li\u1ec7u ph\u00e1p statin.<\/p>\n<p>\u201c\u0110\u1ed1i v\u1edbi \u0111a s\u1ed1 b\u1ec7nh nh\u00e2n, statin r\u1ea5t an to\u00e0n v\u00e0 c\u1ea7n \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o ch\u1ec9 \u0111\u1ecbnh v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 cao \u0111\u1ec3 ng\u01b0\u1eddi b\u1ec7nh \u0111\u01b0\u1ee3c h\u01b0\u1edfng l\u1ee3i cao nh\u1ea5t, \u0111\u1eb7c bi\u1ec7t l\u00e0 v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 b\u1ec7nh tim m\u1ea1ch, ti\u1ec3u \u0111\u01b0\u1eddng v\u00e0 b\u1ec7nh nh\u00e2n d\u1ef1 ph\u00f2ng ban \u0111\u1ea7u v\u1edbi nhi\u1ec1u y\u1ebfu t\u1ed1 nguy c\u01a1\u201d \u00f4ng Dave Dixon, PharmD, CLS, FNLA, FACC, ph\u00f3 gi\u00e1o s\u01b0 v\u00e0 ph\u00f3 ch\u1ee7 t\u1ecbch d\u1ecbch v\u1ee5l\u00e2m s\u00e0ng t\u1ea1i tr\u01b0\u1eddng \u0111\u1ea1i h\u1ecdc Virginia Commonwealth University School of Pharmacy \u1edf Richmond, cho bi\u1ebft.<\/p>\n<p>B\u1ea3n b\u00e1o c\u00e1o h\u01a1n 70 trang \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean chuy\u00ean trang \u00a0\u00a0x\u01a1 c\u1ee9ng \u0111\u1ed9ng m\u1ea1ch, huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch, sinh h\u1ecdc m\u1ea1ch m\u00e1u\u00a0v\u00e0o th\u00e1ng 12 n\u0103m 2018 d\u1ef1a tr\u00ean 30 n\u0103m nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng cho th\u1ea5y c\u00e1c statin \u00edt c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng. Ch\u1eb3ng h\u1ea1n, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u k\u1ebft lu\u1eadn r\u1eb1ng:<\/p>\n<ul>\n<li>B\u1ec7nh c\u01a1 bao g\u1ed3m ti\u00eau c\u01a1 v\u00e2n x\u1ea3y ra \u1edf d\u01b0\u1edbi 0,1% b\u1ec7nh nh\u00e2n \u0111i\u1ec1u tr\u1ecb v\u1edbi statin.<\/li>\n<li>C\u00e1c Tri\u1ec7u ch\u1ee9ng kh\u00f4ng nghi\u00eam tr\u1ecdng v\u1ec1 c\u01a1 th\u01b0\u1eddng \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb statin v\u00e0 g\u00e2y tr\u1edf ng\u1ea1i trong vi\u1ec7c tu\u00e2n th\u1ee7 \u0111i\u1ec1u tr\u1ecb, nh\u01b0ng nh\u00ecn chung, \u00edt h\u01a1n 1% b\u1ec7nh nh\u00e2n \u0111i\u1ec1u tr\u1ecb statin b\u1ecb c\u00e1c tri\u1ec7u ch\u1ee9ng c\u01a1 c\u00f3 ngu\u1ed3n g\u1ed1c d\u01b0\u1ee3c l\u00fd.<\/li>\n<li>Nhi\u1ec5m \u0111\u1ed9c gan n\u1eb7ng r\u1ea5t hi\u1ebfm khi x\u1ea3y ra, b\u00e1o c\u00e1o trong kho\u1ea3ng 0,001% b\u1ec7nh nh\u00e2n.<\/li>\n<li>Statins l\u00e0m t\u0103ng nh\u1eb9 nguy c\u01a1 m\u1eafc b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng trong c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng th\u1eddi gian l\u00ean \u0111\u1ebfn 5 n\u0103m.<\/li>\n<\/ul>\n<h2><strong>\u0110au c\u01a1 b\u1eafp v\u00e0 c\u00e1c statin<\/strong><\/h2>\n<p>Kathleen Lusk, PharmD, BCPS \u0111\u00e3 g\u1eb7p kh\u00f4ng \u00edt b\u1ec7nh nh\u00e2n d\u1eebng s\u1eed d\u1ee5ng statin v\u00ec c\u01a1n \u0111au c\u01a1 m\u00e0 c\u00f3 th\u1ec3 do c\u00e1c nguy\u00ean nh\u00e2n kh\u00e1c nh\u01b0 b\u1ecb th\u01b0\u01a1ng hay t\u1eadp luy\u1ec7n th\u1ec3 thao.<\/p>\n<p>\u201cTh\u00f4ng th\u01b0\u1eddng, b\u1ec7nh nh\u00e2n ng\u1eebng d\u00f9ng statin tr\u01b0\u1edbc khi trao \u0111\u1ed5i v\u1edbi nh\u00e2n vi\u00ean y t\u1ebf\u201d \u00f4ng Lusk, \u0111ang l\u00e0m vi\u1ec7c t\u1ea1i m\u1ed9t ph\u00f2ng kh\u00e1m tim m\u1ea1ch li\u00ean k\u1ebft v\u1edbi Trung t\u00e2m khoa h\u1ecdc y t\u1ebf \u0111\u1ea1i h\u1ecdc Texas \u1edf San Antonio cho\u00a0 bi\u1ebft. \u201cM\u1eb7t kh\u00e1c, m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n do d\u1ef1 v\u1ec1 th\u1eddi \u0111i\u1ec3m b\u1eaft \u0111\u1ea7u ho\u1eb7c b\u1eaft \u0111\u1ea7u s\u1eed d\u1ee5ng l\u1ea1i statin.\u201d<\/p>\n<p>\u0110au c\u01a1 l\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn nh\u1ea5t li\u00ean quan \u0111\u1ebfn s\u1eed d\u1ee5ng statin v\u00e0 khi t\u00ecm ki\u1ebfm tr\u00ean internet s\u1ebd cho ra m\u1ed9t lo\u1ea1t c\u00e1c b\u00e0i vi\u1ebft li\u00ean quan.<\/p>\n<p>Tuy\u00ean b\u1ed1 c\u1ee7a AHA cung c\u1ea5p m\u1ed9t cu\u1ed9c th\u1ea3o lu\u1eadn chuy\u00ean s\u00e2u v\u1ec1 c\u01a1n \u0111au c\u01a1 v\u00e0 c\u00e1c bi\u1ec7n ph\u00e1p ki\u1ec3m so\u00e1t \u0111au c\u01a1 h\u1ee3p l\u00fd \u1edf b\u1ec7nh nh\u00e2n d\u00f9ng statin.<\/p>\n<p>\u201cT\u00f4i \u0111\u00e1nh gi\u00e1 cao c\u00e1c cu\u1ed9c th\u1ea3o lu\u1eadn v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng CK (creatine kinase) \u0111\u1ec3 lo\u1ea1i tr\u1eeb c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 c\u01a1 nghi\u00eam tr\u1ecdng nh\u01b0 ti\u00eau c\u01a1 v\u00e2n c\u0169ng nh\u01b0 m\u1ed9t bi\u1ec7n ph\u00e1p \u0111\u1ec3 tr\u1ea5n an b\u1ec7nh nh\u00e2n r\u1eb1ng t\u1ed5n th\u01b0\u01a1ng c\u01a1 kh\u00f4ng x\u1ea3y ra\u201d Lusk, ph\u00f3 gi\u00e1o s\u01b0 t\u1ea1i \u0111\u1ea1i h\u1ecdc University of the Incarnate Word Feik School of Pharmacy \u1edf San Antonio cho bi\u1ebft.<\/p>\n<p>M\u1ed1i quan t\u00e2m m\u1edbi xung quanh vi\u1ec7c s\u1eed d\u1ee5ng statin bao g\u1ed3m l\u00e0m th\u1ebf n\u00e0o n\u00f3 c\u00f3 th\u1ec3 li\u00ean quan v\u1edbi b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng, ung th\u01b0 v\u00e0 th\u1eadm ch\u00ed m\u1ed9t s\u1ed1 r\u1ed1i lo\u1ea1n th\u1ea7n kinh.<\/p>\n<p>\u201cNh\u1eefng tuy\u00ean b\u1ed1 khoa h\u1ecdc th\u1ea3o lu\u1eadn v\u1ec1 t\u1ea7m quan tr\u1ecdng c\u1ee7a vi\u1ec7c c\u00e2n nh\u1eafc gi\u1eefa l\u1ee3i\u00a0 \u00edch v\u1edbi nguy c\u01a1, \u0111\u1eb7c bi\u1ec7t l\u00e0 nguy c\u01a1 m\u1eafc b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng\u201d Lusk cho bi\u1ebft.<\/p>\n<h2><strong>T\u00f3m l\u1ea1i<\/strong><\/h2>\n<p>D\u01b0\u1ee3c s\u0129 n\u00ean c\u1ea3m th\u1ea5y tho\u1ea3i m\u00e1i khi th\u1ea3o lu\u1eadn v\u1edbi b\u1ec7nh nh\u00e2n v\u1ec1 nh\u1eefng l\u1ee3i \u00edch v\u00e0 \u00a0nguy c\u01a1 c\u1ee7a statin. Lusk cho bi\u1ebft d\u01b0\u1ee3c s\u0129 c\u00f3 th\u1ec3 th\u1ea3o lu\u1eadn v\u1ec1 nh\u1eefng t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a thu\u1ed1c v\u00e0 nh\u1eefng g\u00ec b\u1ec7nh nh\u00e2n n\u00ean l\u00e0m n\u1ebfu h\u1ecd th\u1ea5y \u0111au c\u01a1.<\/p>\n<p>\u201cH\u1ecd c\u00f3 th\u1ec3 xem x\u00e9t v\u1ec1 c\u00e1c \u0111\u1eb7c t\u00ednh statin nh\u01b0 \u00a0statin n\u00e0o c\u00f3 nhi\u1ec1u kh\u1ea3 n\u0103ng g\u00e2y ra \u0111au c\u01a1 v\u00e0 l\u00e0m th\u1ebf n\u00e0o \u0111\u1ec3 ki\u1ec3m so\u00e1t h\u1ee3p l\u00fd c\u01a1n \u0111au \u00a0n\u1ebfu n\u00f3 x\u1ea3y ra\u201d, b\u00e0 n\u00f3i. \u201cKh\u00f4ng nh\u1ea5t thi\u1ebft ph\u1ea3i tr\u00e1nh c\u00e1c statin. \u0110\u00fang h\u01a1n, c\u00f3 th\u1ec3 ch\u1ec9 \u0111\u1ecbnh m\u1ed9t li\u1ec1u th\u1ea5p h\u01a1n ho\u1eb7c m\u1ed9t statin kh\u00e1c .\u201d<\/p>\n<p>D\u01b0\u1ee3c s\u0129 trao \u0111\u1ed5i v\u1edbi b\u1ec7nh nh\u00e2n \u0111ang s\u1eed d\u1ee5ng statin c\u00f3 th\u1ec3 t\u1eadp trung v\u00e0o c\u00e1c c\u00e2u h\u1ecfi ki\u1ec3m tra t\u1ed5ng qu\u00e1t h\u01a1n \u0111\u1ec3 tr\u00e1nh d\u1eabn \u0111\u1ebfn b\u1ec7nh nh\u00e2n ngh\u0129 r\u1eb1ng \u0111au c\u01a1 c\u00f3 th\u1ec3 x\u1ea3y ra, Lusk cho bi\u1ebft.<\/p>\n<p>V\u00ed d\u1ee5, thay v\u00ec h\u1ecfi b\u1ec7nh nh\u00e2n \u201cB\u1ea1n c\u00f3 b\u1ecb \u0111au c\u01a1 kh\u00f4ng?\u201d th\u00ec h\u00e3y h\u1ecfi \u201cB\u1ea1n c\u00f3 nh\u1eadn th\u1ea5y b\u1ea5t k\u1ef3 thay \u0111\u1ed5i n\u00e0o k\u1ec3 t\u1eeb khi b\u1eaft \u0111\u1ea7u d\u00f9ng thu\u1ed1c n\u00e0y kh\u00f4ng?\u201d<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nh\u1ea7m l\u1eabn v\u1ec1 l\u1ee3i \u00edch c\u1ee7a Statin? Hi\u1ec7p h\u1ed9i Tim m\u1ea1ch M\u1ef9 (AHA) tuy\u00ean b\u1ed1 c\u00e2u tr\u1ea3 l\u1eddi. Ng\u01b0\u1eddi d\u1ecbch: L\u01b0u Th\u1ee5y L\u1ec7 Mai \u2013 sinh vi\u00ean D\u01b0\u1ee3c \u2013 Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc Y khoa Ph\u1ea1m Ng\u1ecdc Th\u1ea1ch Ng\u01b0\u1eddi hi\u1ec7u \u0111\u00ednh: Ths.Nguy\u1ec5n Th\u1ecb Thu H\u01b0\u01a1ng- Khoa D\u01b0\u1ee3c \u2013Vi\u1ec7n B\u1ecfng L\u00ea H\u1eefu Tr\u00e1c Ngu\u1ed3n: Confused about statin [&#8230;]\n","protected":false},"author":1,"featured_media":6866,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-6862","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/6862","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=6862"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/6862\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/6866"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=6862"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=6862"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=6862"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}