{"id":68112,"date":"2024-03-07T14:38:31","date_gmt":"2024-03-07T07:38:31","guid":{"rendered":"https:\/\/vnras.com\/drug\/?p=68112"},"modified":"2024-05-06T11:00:06","modified_gmt":"2024-05-06T04:00:06","slug":"phan-loai-cac-nhom-thuoc-khang-virus-va-nhung-luu-y-khi-su-dung","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/phan-loai-cac-nhom-thuoc-khang-virus-va-nhung-luu-y-khi-su-dung\/","title":{"rendered":"Ph\u00e2n lo\u1ea1i c\u00e1c nh\u00f3m thu\u1ed1c kh\u00e1ng virus v\u00e0 nh\u1eefng l\u01b0u \u00fd khi s\u1eed d\u1ee5ng"},"content":{"rendered":"<p><strong>Virus l\u00e0 nh\u1eefng sinh v\u1eadt nh\u1ecf, c\u00f3 th\u1ec3 g\u00e2y ra nhi\u1ec1u lo\u1ea1i b\u1ec7nh nguy hi\u1ec3m \u0111\u1ed1i v\u1edbi con ng\u01b0\u1eddi. V\u1eady, thu\u1ed1c kh\u00e1ng virus l\u00e0 g\u00ec? B\u00e0i vi\u1ebft d\u01b0\u1edbi \u0111\u00e2y, D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng s\u1ebd cung c\u1ea5p cho b\u1ea1n \u0111\u1ecdc nh\u1eefng th\u00f4ng tin chi ti\u1ebft v\u1ec1 c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1ng virus hi\u1ec7n nay<\/strong><\/p>\n<h2>Virus l\u00e0 g\u00ec?<\/h2>\n<figure id=\"attachment_68114\" aria-describedby=\"caption-attachment-68114\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68114\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-0.jpg\" alt=\"Virus l\u00e0 g\u00ec?\" width=\"1200\" height=\"1200\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-0.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-0-400x400.jpg 400w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-0-800x800.jpg 800w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-0-280x280.jpg 280w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-0-768x768.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-0-350x350.jpg 350w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-0-100x100.jpg 100w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68114\" class=\"wp-caption-text\">Virus l\u00e0 g\u00ec?<\/figcaption><\/figure>\n<p>Virus l\u00e0 nh\u1eefng sinh v\u1eadt nh\u1ecf, c\u00f3 c\u1ea5u t\u1ea1o \u0111\u01a1n gi\u1ea3n. Virus c\u00f3 th\u1ec3 g\u00e2y ra nhi\u1ec1u lo\u1ea1i b\u1ec7nh nguy hi\u1ec3m cho con ng\u01b0\u1eddi nh\u01b0 c\u00fam, \u0111\u1eadu m\u00f9a, zona, vi\u00eam \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p, th\u1ee7y \u0111\u1eadu, b\u1ec7nh AIDS v\u00e0 c\u00f3 th\u1ec3 l\u00e0 nguy\u00ean nh\u00e2n g\u00e2y n\u00ean ung th\u01b0.<\/p>\n<p>C\u1ea5u t\u1ea1o c\u1ee7a virus g\u1ed3m m\u1ed9t m\u1ed9t l\u1edbp v\u1ecf g\u1ecdi l\u00e0 capsid bao b\u1ecdc m\u1ed9t nh\u00e2n acid nucleic.<\/p>\n<p>Virus s\u1ed1ng d\u1ef1a v\u00e0o t\u1ebf b\u00e0o v\u1eadt ch\u1ee7, ch\u00fang s\u1eed d\u1ee5ng b\u1ed9 m\u00e1y h\u00f3a t\u00ednh c\u1ee7a c\u00e1c t\u1ebf b\u00e0o v\u1eadt ch\u1ee7 \u0111\u1ec3 t\u1ed5ng h\u1ee3p acid nucleic, protein v\u00e0 \u0111\u00e2y c\u0169ng ch\u00ednh l\u00e0 nguy\u00ean nh\u00e2n g\u00e2y b\u1ec7nh c\u1ee7a virus.<\/p>\n<h2>Ph\u00e2n lo\u1ea1i c\u00e1c virus<\/h2>\n<p>Kh\u00f4ng gi\u1ed1ng nh\u01b0 vi khu\u1ea9n, c\u00e1c lo\u1ea1i virus trong nh\u00e2n c\u00f3 ch\u1ee9a ARN (acid ribonucleic) ho\u1eb7c ADN (acid deoxyribonucleic). Do \u0111\u00f3, virus \u0111\u01b0\u1ee3c ph\u00e2n th\u00e0nh 2 nh\u00f3m d\u1ef1a theo \u0111\u1eb7c \u0111i\u1ec3m c\u1ee7a acid nucleic v\u00e0 ADN virus v\u00e0 ARN virus.<\/p>\n<p>B\u00ean c\u1ea1nh \u0111\u00f3, virus c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e2n lo\u1ea1i d\u1ef1a theo h\u00ecnh d\u00e1ng, theo l\u1edbp b\u1ecdc ho\u1eb7c theo c\u0103n b\u1ec7nh m\u00e0 ch\u00fang g\u00e2y ra.<\/p>\n<p>Qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n v\u00e0 nh\u00e2n l\u00ean c\u1ee7a virus trong t\u1ebf b\u00e0o v\u1eadt ch\u1ee7 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c chia l\u00e0m 5 giai \u0111o\u1ea1n bao g\u1ed3m: H\u1ea5p ph\u1ee5, c\u1edfi v\u1ecf, t\u1ed5ng h\u1ee3p, l\u1eafp r\u00e1p v\u00e0 ph\u00f3ng th\u00edch.<\/p>\n<p>D\u1ef1a v\u00e0o \u0111\u00f3, c\u00e1c thu\u1ed1c kh\u00e1ng virus c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e2n chia th\u00e0nh c\u00e1c nh\u00f3m t\u00e1c \u0111\u1ed9ng l\u00ean t\u1eebng qu\u00e1 tr\u00ecnh tr\u00ean.<\/p>\n<h2>Con \u0111\u01b0\u1eddng l\u00e2y truy\u1ec1n c\u1ee7a virus<\/h2>\n<figure id=\"attachment_68115\" aria-describedby=\"caption-attachment-68115\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68115\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-1.jpg\" alt=\"Con \u0111\u01b0\u1eddng l\u00e2y truy\u1ec1n c\u1ee7a virus\" width=\"1200\" height=\"1200\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-1.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-1-400x400.jpg 400w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-1-800x800.jpg 800w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-1-280x280.jpg 280w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-1-768x768.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-1-350x350.jpg 350w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-1-100x100.jpg 100w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68115\" class=\"wp-caption-text\">Con \u0111\u01b0\u1eddng l\u00e2y truy\u1ec1n c\u1ee7a virus<\/figcaption><\/figure>\n<p>Virus l\u00e2y truy\u1ec1n t\u1eeb ng\u01b0\u1eddi qua ng\u01b0\u1eddi ho\u1eb7c t\u1eeb \u0111\u1ed9ng v\u1eadt qua ng\u01b0\u1eddi theo nhi\u1ec1u con \u0111\u01b0\u1eddng kh\u00e1c nhau nh\u01b0:<\/p>\n<ul>\n<li>L\u00e2y truy\u1ec1n qua \u0111\u01b0\u1eddng m\u00e1u.<\/li>\n<li>L\u00e2y truy\u1ec1n qua \u0111\u01b0\u1eddng t\u00ecnh d\u1ee5c kh\u00f4ng an to\u00e0n.<\/li>\n<li>L\u00e2y truy\u1ec1n t\u1eeb m\u1eb9 sang con.<\/li>\n<li>L\u00e2y truy\u1ec1n qua \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p.<\/li>\n<\/ul>\n<h2>C\u00e1c nh\u00f3m thu\u1ed1c kh\u00e1ng virus<\/h2>\n<p>Nguy\u00ean t\u1eafc c\u1ee7a vi\u1ec7c ph\u00e2n lo\u1ea1i c\u00e1c thu\u1ed1c kh\u00e1ng virus c\u0169ng t\u01b0\u01a1ng t\u1ef1 nh\u01b0 c\u00e1c thu\u1ed1c kh\u00e1c. Tuy nhi\u00ean, c\u00f3 nhi\u1ec1u y\u1ebfu t\u1ed1 g\u00e2y kh\u00f3 kh\u0103n trong vi\u1ec7c thi\u1ebft k\u1ebf c\u00e1c thu\u1ed1c kh\u00e1ng virus do ch\u00fang c\u00f3 kh\u1ea3 n\u0103ng thay \u0111\u1ed5i, c\u00f3 th\u1ec3 k\u1ec3 \u0111\u1ebfn nh\u01b0:<\/p>\n<ul>\n<li>Thay \u0111\u1ed5i t\u00ednh kh\u00e1ng nguy\u00ean.<\/li>\n<li>Thay \u0111\u1ed5i s\u1ef1 ph\u1ee5 thu\u1ed9c c\u1ee7a virus v\u00e0o enzyme c\u1ee7a t\u1ebf b\u00e0o v\u1eadt ch\u1ee7.<\/li>\n<li>Thay \u0111\u1ed5i th\u1eddi gian ti\u1ec1m t\u00e0ng kh\u00f4ng c\u00f3 tri\u1ec7u ch\u1ee9ng.<\/li>\n<\/ul>\n<p>D\u1ef1a tr\u00ean qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n c\u1ee7a virus, c\u00e1c thu\u1ed1c kh\u00e1ng virus hi\u1ec7n nay \u0111\u01b0\u1ee3c ph\u00e2n th\u00e0nh 8 nh\u00f3m:<\/p>\n<ul>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh phi\u00ean m\u00e3.<\/li>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh d\u1ecbch m\u00e3.<\/li>\n<li>Thu\u1ed1c ng\u0103n c\u1ea3n virus g\u1eafn v\u00e0o receptor c\u1ee7a t\u1ebf b\u00e0o v\u1eadt ch\u1ee7, ng\u0103n c\u1ea3n qu\u00e1 tr\u00ecnh th\u00e2m nh\u1eadp ho\u1eb7c c\u1edfi \u00e1o.<\/li>\n<li>Thu\u1ed1c c\u1ea3n tr\u1edf c\u00e1c c\u00e1c protein \u0111i\u1ec1u ch\u1ec9nh c\u1ee7a virus.<\/li>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf c\u00e1c enzym virus.<\/li>\n<li>Thu\u1ed1c c\u1ea3n tr\u1edf qu\u00e1 tr\u00ecnh l\u1eafp r\u00e1p c\u1ee7a c\u00e1c protein virus.<\/li>\n<li>Thu\u1ed1c c\u1ea3n tr\u1edf qu\u00e1 tr\u00ecnh phosphoryl, glycosyl, sulfat h\u00f3a.<\/li>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf gi\u1ea3i ph\u00f3ng virus ra kh\u1ecfi t\u1ebf b\u00e0o.<\/li>\n<\/ul>\n<p>Tuy nhi\u00ean, \u0111\u1ec3 t\u1ea1o \u0111i\u1ec1u ki\u1ec7n thu\u1eadn l\u1ee3i cho qu\u00e1 t\u00ecnh \u0111i\u1ec1u tr\u1ecb, c\u00e1c thu\u1ed1c kh\u00e1ng virus c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e2n lo\u1ea1i theo nh\u00f3m b\u1ec7nh m\u00e0 virus \u0111\u00f3 g\u00e2y ra:<\/p>\n<ul>\n<li>Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb virus herpes.<\/li>\n<li>Thu\u1ed1c kh\u00e1ng HIV.<\/li>\n<li>Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb virus vi\u00eam gan.<\/li>\n<li>Thu\u1ed1c ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb c\u00fam.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb virus Herpes<\/h2>\n<p>Herpes virus (HSV) l\u00e0 lo\u1ea1i virus ch\u1ee9a DNA g\u00e2y ra c\u00e1c b\u1ec7nh nh\u01b0 m\u1ee5n r\u1ed9p sinh d\u1ee5c, th\u1ee7y \u0111\u1eadu, vi\u00eam v\u00f5ng m\u1ea1c v\u00e0 b\u1ec7nh b\u1ea1ch c\u1ea7u \u0111\u01a1n nh\u00e2n<\/p>\n<p>nhi\u1ec5m tr\u00f9ng.<\/p>\n<p>C\u00e1c thu\u1ed1c kh\u00e1ng virus can thi\u1ec7p v\u00e0o qu\u00e1 tr\u00ecnh sao ch\u00e9p DNA s\u1ebd c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng l\u1ea1i virus herpes.<br \/>\nHSV-1 th\u01b0\u1eddng g\u00e2y ra c\u00e1c b\u1ec7nh \u1edf m\u1eb7t, mi\u1ec7ng, n\u00e3o, th\u1ef1c qu\u1ea3n, da trong khi \u0111\u00f3, HSV-2 th\u01b0\u1eddng g\u00e2y ra c\u00e1c b\u1ec7nh \u1edf m\u00e0ng n\u00e3o, tr\u1ef1c tr\u00e0ng, da, tay, b\u1ed9 ph\u1eadn sinh d\u1ee5c.<\/p>\n<p>Herpes virus c\u00f3 th\u1ec3 t\u1ef1 kh\u1ecfi m\u00e0 kh\u00f4ng c\u1ea7n b\u1ea5t k\u1ef3 m\u1ed9t bi\u1ec7n ph\u00e1p can thi\u1ec7p n\u00e0o. Tuy nhi\u00ean, trong tr\u01b0\u1eddng h\u1ee3p virus ph\u00e1t tri\u1ec3n m\u1ea1nh, g\u00e2y ra nh\u1eefng tri\u1ec7u ch\u1ee9ng kh\u00f3 ch\u1ecbu cho ng\u01b0\u1eddi b\u1ec7nh, c\u1ea7n c\u00f3 ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 h\u1ea1n ch\u1ebf t\u00ecnh tr\u1ea1ng l\u00e2y lan v\u00e0 nh\u1eefng bi\u1ebfn ch\u1ee9ng c\u00f3 th\u1ec3 x\u1ea3y ra.<\/p>\n<p>C\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb virus Herpes c\u00f3 c\u1ea5u tr\u00fac nucleoside. T\u1ea5t c\u1ea3 c\u00e1c thu\u1ed1c \u0111\u1ec1u \u1edf d\u1ea1ng ti\u1ec1n ch\u1ea5t, sau khi v\u00e0o c\u01a1 th\u1ec3 s\u1ebd \u0111\u01b0\u1ee3c ho\u1ea1t h\u00f3a \u0111\u1ec3 tr\u1edf th\u00e0nh triphosphat l\u00e0 d\u1ea1ng c\u00f3 ho\u1ea1t t\u00ednh nh\u1edd qu\u00e1 tr\u00ecnh phosphoryl h\u00f3a.<\/p>\n<p>Acyclovir c\u00f3 c\u1ea5u tr\u00fac t\u01b0\u01a1ng t\u1ef1 deoxyguanosine nh\u01b0ng kh\u00f4ng c\u00f3 ph\u1ea7n \u0111\u01b0\u1eddng. Acyclovir c\u00f3 t\u00e1c d\u1ee5ng t\u01b0\u01a1ng \u0111\u1ed1i ch\u1ecdn l\u1ecdc tr\u00ean t\u1ebf b\u00e0o nhi\u1ec5m virus.<\/p>\n<p>C\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb virus herpes \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf th\u00e0nh d\u1ea1ng thu\u1ed1c u\u1ed1ng t\u00e1c d\u1ee5ng to\u00e0n th\u00e2n bao g\u1ed3m:<\/p>\n<ul>\n<li>Acyclovir (Sitavig, Zovirax, Acyclovir STADA, Agiclovir, Medskin,&#8230;).<\/li>\n<li>Valacyclovir (Valtrex, Valacyclovir Tablets USP 1000 mg,&#8230;).<\/li>\n<li>Famciclovir (Famvir, Famciclovir STADA 500mg).<\/li>\n<\/ul>\n<figure id=\"attachment_68116\" aria-describedby=\"caption-attachment-68116\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68116\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-2.jpg\" alt=\"C\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb virus herpes \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf th\u00e0nh d\u1ea1ng thu\u1ed1c u\u1ed1ng t\u00e1c d\u1ee5ng to\u00e0n th\u00e2n\" width=\"1200\" height=\"850\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-2.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-2-565x400.jpg 565w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-2-1129x800.jpg 1129w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-2-768x544.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-2-350x248.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68116\" class=\"wp-caption-text\">C\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb virus herpes \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf th\u00e0nh d\u1ea1ng thu\u1ed1c u\u1ed1ng t\u00e1c d\u1ee5ng to\u00e0n th\u00e2n<\/figcaption><\/figure>\n<p>C\u00e1c d\u1ea1ng thu\u1ed1c kh\u00e1ng virus \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf \u1edf d\u1ea1ng thu\u1ed1c b\u00f4i t\u1ea1i ch\u1ed7:<\/p>\n<ul>\n<li>Acyclovir STADA cream.<\/li>\n<li>Mediclovir 3% Medipharco.<\/li>\n<\/ul>\n<figure id=\"attachment_68117\" aria-describedby=\"caption-attachment-68117\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68117\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-3.jpg\" alt=\"C\u00e1c d\u1ea1ng thu\u1ed1c kh\u00e1ng virus \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf \u1edf d\u1ea1ng thu\u1ed1c b\u00f4i t\u1ea1i ch\u1ed7\" width=\"1200\" height=\"850\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-3.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-3-565x400.jpg 565w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-3-1129x800.jpg 1129w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-3-768x544.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-3-350x248.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68117\" class=\"wp-caption-text\">C\u00e1c d\u1ea1ng thu\u1ed1c kh\u00e1ng virus \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf \u1edf d\u1ea1ng thu\u1ed1c b\u00f4i t\u1ea1i ch\u1ed7<\/figcaption><\/figure>\n<h2>Thu\u1ed1c kh\u00e1ng HIV<\/h2>\n<p>Thu\u1ed1c kh\u00e1ng virus HIV hay c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 thu\u1ed1c kh\u00e1ng virus sao ch\u00e9p ng\u01b0\u1ee3c. B\u1ea3n ch\u1ea5t c\u1ee7a HIV (human immunodeficiency virus) l\u00e0 m\u1ed9t lo\u1ea1i virus sao ch\u00e9p ng\u01b0\u1ee3c. D\u1ef1a v\u00e0o qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n c\u1ee7a virus HIV trong t\u1ebf b\u00e0o v\u1eadt ch\u1ee7, c\u00f3 th\u1ec3 nghi\u00ean c\u1ee9u c\u00e1c thu\u1ed1c kh\u00e1ng virus t\u00e1c \u0111\u1ed9ng v\u00e0o c\u00e1c qu\u00e1 tr\u00ecnh sau:<\/p>\n<ul>\n<li>Ng\u0103n c\u1ea3n virus HIV g\u1eafn \u0111\u01b0\u1ee3c v\u00e0o c\u00e1c receptor c\u1ee7a t\u1ebf b\u00e0o.<\/li>\n<li>Ng\u0103n c\u1ea3n s\u1ef1 h\u00f2a m\u00e0ng v\u00e0 tho\u00e1t v\u1ecf c\u1ee7a virus.<\/li>\n<li>K\u00ecm h\u00e3m s\u1ef1 sao ch\u00e9p ng\u01b0\u1ee3c t\u1eeb ARN.<\/li>\n<li>Ng\u0103n c\u1ea3n s\u1ef1 sao m\u00e3 hay ng\u0103n c\u1ea3n s\u1ef1 t\u1ed5ng h\u1ee3p protein c\u1ee7a virus.<\/li>\n<li>K\u00ecm h\u00e3m s\u1ef1 l\u1eafp r\u00e1p hay s\u1ef1 t\u1ed5 h\u1ee3p l\u1ea1i c\u1ee7a virus, k\u00ecm h\u00e3m s\u1ef1 n\u1ea3y ch\u1ed3i.<\/li>\n<li>Ng\u0103n c\u1ea3n qu\u00e1 tr\u00ecnh sao m\u00e3 mu\u1ed9n hay ng\u0103n c\u1ea3n s\u1ef1 t\u1ed5ng h\u1ee3p protein c\u1ee7a virus.<\/li>\n<\/ul>\n<p>\u1ede m\u1ed7i giai \u0111o\u1ea1n, c\u00f3 th\u1ec3 t\u00ecm ra thu\u1ed1c kh\u00e1ng virus th\u00edch h\u1ee3p. Tuy nhi\u00ean, do c\u00f3 nhi\u1ec1u kh\u00f3 kh\u0103n trong qu\u00e1 tr\u00ecnh nghi\u00ean c\u1ee9u, hi\u1ec7n nay, c\u00e1c thu\u1ed1c ch\u1ee7 y\u1ebfu l\u00e0 thu\u1ed1c \u1ee9c ch\u1ebf enzym sao ch\u00e9p ng\u01b0\u1ee3c, protease v\u00e0 integrase.<\/p>\n<p>Enzym sao ch\u00e9p ng\u01b0\u1ee3c (RT) l\u00e0 enzym \u0111\u00f3ng vai tr\u00f2 trong vi\u1ec7c chuy\u1ec3n m\u1ea1ch \u0111\u01a1n ADN c\u1ee7a virus HIV th\u00e0nh ADN m\u1ea1ch k\u00e9p tr\u01b0\u1edbc khi x\u00e2m nh\u1eadp v\u00e0o nhi\u1ec5m s\u1eafc th\u1ec3 c\u1ee7a t\u1ebf b\u00e0o v\u1eadt ch\u1ee7.<\/p>\n<p>Thu\u1ed1c \u1ee9c ch\u1ebf enzym sao ch\u00e9p ng\u01b0\u1ee3c c\u00f3 2 lo\u1ea1i:<\/p>\n<ul>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf nucleoside reverse transcriptase (NRTI): Thu\u1ed1c \u00edt c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ed1i v\u1edbi c\u00e1c t\u1ebf b\u00e0o nhi\u1ec5m HIV, c\u00f3 t\u00e1c d\u1ee5ng r\u1ea5t s\u1edbm \u1edf giai \u0111o\u1ea1n sao ch\u00e9p c\u1ee7a HIV. C\u00e1c thu\u1ed1c trong nh\u00f3m \u0111\u1ec1u \u0111\u01b0\u1ee3c coi l\u00e0 ti\u1ec1n thu\u1ed1c, c\u00f3 c\u1ea5u tr\u00fac t\u01b0\u01a1ng t\u1ef1 nh\u01b0 th\u00e0nh ph\u1ea7n c\u1ea5u t\u1ea1o n\u00ean ADN nh\u01b0ng c\u1ea7n ph\u1ea3i c\u00f3 enzym phosphoryl h\u00f3a m\u1edbi c\u00f3 ho\u1ea1t t\u00ednh. \u0110\u00e2y l\u00e0 nh\u00f3m thu\u1ed1c \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong vi\u1ec7c ph\u1ed1i h\u1ee3p thu\u1ed1c \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb cho b\u1ec7nh nh\u00e2n HIV.<\/li>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf non-nucleoside reverse transcriptase (NNRTI): Thu\u1ed1c \u1ee9c ch\u1ebf enzym sao ch\u00e9p ng\u01b0\u1ee3c kh\u00f4ng ph\u1ea3i nucleoside. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c l\u00e0 g\u1eafn v\u00e0o v\u1ecb tr\u00ed t\u00e1c \u0111\u1ed9ng c\u1ee7a enzym sao ch\u00e9p ng\u01b0\u1ee3c, t\u1eeb \u0111\u00f3 l\u00e0m thay \u0111\u1ed5i h\u00ecnh d\u00e1ng c\u1ee7a v\u1ecb tr\u00ed n\u00e0y d\u1eabn \u0111\u1ebfn enzyme b\u1ecb m\u1ea5t ho\u1ea1t t\u00ednh. NNRTI kh\u00f4ng tr\u1ea3i qua giai \u0111o\u1ea1n phosphoryl h\u00f3a nh\u01b0ng ch\u1ec9 c\u00f3 t\u00e1c \u0111\u1ed9ng \u0111\u1ed1i v\u1edbi virus HIV-1.<\/li>\n<\/ul>\n<p>Thu\u1ed1c \u1ee9c ch\u1ebf enzyme Integrase v\u00e0 protease v\u1eabn \u0111ang trong qu\u00e1 tr\u00ecnh nghi\u00ean c\u1ee9u.<\/p>\n<p>C\u00e1c thu\u1ed1c ch\u1ed1ng HIV hi\u1ec7n nay c\u00f2n \u0111\u1eaft, nhi\u1ec1u thu\u1ed1c v\u1eabn \u1edf giai \u0111o\u1ea1n th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng.<\/p>\n<h3>Thu\u1ed1c \u1ee9c ch\u1ebf NRT<\/h3>\n<h4>Zidovudine (azidothymidine, AZT)<\/h4>\n<p>Zidovudine l\u00e0 thu\u1ed1c t\u1ed5ng h\u1ee3p, ban \u0111\u1ea7u \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng l\u00e0m thu\u1ed1c ch\u1ed1ng ung th\u01b0, sau \u0111\u00f3, v\u00e0o n\u0103m 1974, Ostertag \u0111\u00e3 th\u1ea5y t\u00e1c d\u1ee5ng kh\u00e1ng virus c\u1ee7a thu\u1ed1c. V\u00e0o n\u0103m 1985 th\u00ec th\u1ea5y Zidovudine c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf HIV-1 khi ti\u1ebfn h\u00e0nh nghi\u00ean c\u1ee9u tr\u00ean in vitro.<\/p>\n<h5>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h5>\n<p>Sau khi x\u00e2m nh\u1eadp \u0111\u01b0\u1ee3c v\u00e0o t\u1ebf b\u00e0o, Zidovudine c\u1ea7n tr\u1ea3i qua qu\u00e1 tr\u00ecnh phosphoryl h\u00f3a \u0111\u1ec3 t\u1ea1o th\u00e0nh Zidovudine 5-triphosphate c\u00f3 ho\u1ea1t t\u00ednh.<br \/>\nZidovudine 5-triphosphate tranh ch\u1ea5p v\u1edbi deoxythymidine triphosphate c\u1ee7a enzyme sao ch\u00e9p ng\u01b0\u1ee3c, b\u00ean c\u1ea1nh \u0111\u00f3, ho\u1ea1t ch\u1ea5t n\u00e0y c\u00f2n tranh ch\u1ea5p v\u1edbi thymidine triphosphate t\u1eeb \u0111\u00f3 t\u1ea1o ra nh\u1eefng ADN provirus kh\u00f4ng ho\u00e0n ch\u1ec9nh.<\/p>\n<p>Khi nghi\u00ean c\u1ee9u tr\u00ean in vitro th\u1ea5y Zidovudine c\u00f3 t\u00e1c d\u1ee5ng kh\u00e1ng HIV-1, HIV-2 v\u00e0 c\u1ea3 c\u00e1c virus h\u01b0\u1edbng lympho T c\u1ee7a ng\u01b0\u1eddi.<\/p>\n<h5>Ch\u1ec9 \u0111\u1ecbnh v\u00e0 li\u1ec1u d\u00f9ng<\/h5>\n<p>M\u1ed7i l\u1ea7n u\u1ed1ng 200mg, c\u00e1ch 8 gi\u1edd u\u1ed1ng l\u1ea1i m\u1ed9t l\u1ea7n ho\u1eb7c m\u1ed7i l\u1ea7n u\u1ed1ng 100mg, ng\u00e0y u\u1ed1ng 5 l\u1ea7n.<\/p>\n<p>S\u1eed d\u1ee5ng li\u00ean t\u1ee5c.<\/p>\n<p>C\u00f3 th\u1ec3 k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf enzym sao ch\u00e9p ng\u01b0\u1ee3c kh\u00e1c ho\u1eb7c thu\u1ed1c \u1ee9c ch\u1ebf protease.<\/p>\n<h5>Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng<\/h5>\n<figure id=\"attachment_68118\" aria-describedby=\"caption-attachment-68118\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68118\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-4.jpg\" alt=\"Thu\u1ed1c kh\u00e1ng virus ch\u1ee9a Zidovudine\" width=\"1200\" height=\"850\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-4.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-4-565x400.jpg 565w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-4-1129x800.jpg 1129w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-4-768x544.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-4-350x248.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68118\" class=\"wp-caption-text\">Thu\u1ed1c kh\u00e1ng virus ch\u1ee9a Zidovudine<\/figcaption><\/figure>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Retrovir.<\/p>\n<p>T\u00ean th\u01b0\u01a1ng m\u1ea1i: AZT, Videx EC.<\/p>\n<h4>Didanosine (ddI)<\/h4>\n<p>Didanosine c\u00f3 b\u1ea3n ch\u1ea5t t\u01b0\u01a1ng t\u1ef1 nh\u01b0 nucleoside purin, \u0111\u00e3 \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u t\u1eeb n\u0103m 1989 v\u00e0 ch\u00ednh th\u1ee9c d\u00f9ng \u0111i\u1ec1u tr\u1ecb t\u1eeb cu\u1ed1i n\u0103m 1991.<br \/>\nDidanosine c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ed1i v\u1edbi c\u1ea3 HIV-1 v\u00e0 HIV-2.<\/p>\n<h5>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h5>\n<p>Sau khi th\u00e2m nh\u1eadp v\u00e0o t\u1ebf b\u00e0o, Didanosine s\u1ebd \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a th\u00e0nh Deoxyadenosine triphosphate (dd ATP) d\u01b0\u1edbi t\u00e1c d\u1ee5ng c\u1ee7a enzym chuy\u1ec3n h\u00f3a n\u1ed9i b\u00e0o.<\/p>\n<p>Deoxyadenosine triphosphate (dd ATP) sau \u0111\u00f3 s\u1ebd tranh ch\u1ea5p v\u1edbi dATP t\u1eeb \u0111\u00f3 \u1ee9c ch\u1ebf enzym sao ch\u00e9p ng\u01b0\u1ee3c c\u1ee7a virus, ng\u0103n c\u1ea3n s\u1ef1 k\u00e9o d\u00e0i chu\u1ed7i ADN v\u00e0 ng\u0103n c\u1ea3n qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p ADN provirus.<\/p>\n<h5>Ch\u1ec9 \u0111\u1ecbnh v\u00e0 li\u1ec1u l\u01b0\u1ee3ng<\/h5>\n<p>S\u1eed d\u1ee5ng cho tr\u1ebb tr\u00ean 6 th\u00e1ng tu\u1ed5i, ng\u01b0\u1eddi l\u1edbn nhi\u1ec5m HIV nh\u01b0ng kh\u00f4ng dung n\u1ea1p v\u1edbi li\u1ec7u ph\u00e1p AZT (Zidovudine) ho\u1eb7c s\u1eed d\u1ee5ng AZT (Zidovudine) tr\u00ean 4 th\u00e1ng nh\u01b0ng t\u00ecnh tr\u1ea1ng b\u1ec7nh v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n nhi\u1ec1u.<\/p>\n<p>Li\u1ec1u d\u00f9ng cho ng\u01b0\u1eddi l\u1edbn: M\u1ed7i l\u1ea7n u\u1ed1ng 200mg, ng\u00e0y u\u1ed1ng 2 l\u1ea7n. C\u00f3 th\u1ec3 c\u00e2n nh\u1eafc gi\u1ea3m li\u1ec1u n\u1ebfu b\u1ec7nh nh\u00e2n c\u00f3 c\u00e2n n\u1eb7ng th\u1ea5p.<\/p>\n<p>Tr\u1ebb em s\u1eed d\u1ee5ng li\u1ec1u theo di\u1ec7n t\u00edch c\u01a1 th\u1ec3.<\/p>\n<p>Th\u1eddi \u0111i\u1ec3m u\u1ed1ng thu\u1ed1c: U\u1ed1ng l\u00fac \u0111\u00f3i, tr\u01b0\u1edbc b\u1eefa \u0103n 1 gi\u1edd. N\u00ean nhai ho\u1eb7c h\u00f2a vi\u00ean thu\u1ed1c cho tan r\u1ed3i u\u1ed1ng ngay.<\/p>\n<h5>M\u1ed9t s\u1ed1 ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng<\/h5>\n<figure id=\"attachment_68119\" aria-describedby=\"caption-attachment-68119\" style=\"width: 1350px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68119\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-5.jpg\" alt=\"Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Didanosine\" width=\"1350\" height=\"1350\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-5.jpg 1350w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-5-400x400.jpg 400w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-5-800x800.jpg 800w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-5-280x280.jpg 280w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-5-768x768.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-5-350x350.jpg 350w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-5-100x100.jpg 100w\" sizes=\"auto, (max-width: 1350px) 100vw, 1350px\" \/><figcaption id=\"caption-attachment-68119\" class=\"wp-caption-text\">Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Didanosine<\/figcaption><\/figure>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Videx, Videx EC.<\/p>\n<p>T\u00ean th\u01b0\u01a1ng m\u1ea1i: Dinex EC.<\/p>\n<h3>Nevirapine &#8211; Thu\u1ed1c \u1ee9c ch\u1ebf NNRT<\/h3>\n<h4>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h4>\n<p>Nevirapine sau khi khu\u1ebfch t\u00e1n v\u00e0o b\u00ean trong t\u1ebf b\u00e0o s\u1ebd g\u1eafn v\u1edbi enzym sao ch\u00e9p ng\u01b0\u1ee3c, t\u1eeb \u0111\u00f3 l\u00e0m thay \u0111\u1ed5i h\u00ecnh d\u00e1ng v\u00e0 g\u00e2y b\u1ea5t ho\u1ea1t enzym. Nevirapine c\u00f3 t\u00e1c d\u1ee5ng m\u1ea1nh \u0111\u1ed1i v\u1edbi HIV-1, bao g\u1ed3m c\u1ea3 virion ngo\u00e0i t\u1ebf b\u00e0o.<\/p>\n<h4>Li\u1ec1u d\u00f9ng<\/h4>\n<p>M\u1ed7i l\u1ea7n u\u1ed1ng 1 vi\u00ean, ng\u00e0y u\u1ed1ng 1-2 l\u1ea7n.<\/p>\n<h4>Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng<\/h4>\n<figure id=\"attachment_68120\" aria-describedby=\"caption-attachment-68120\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68120\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-6.jpg\" alt=\"Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Nevirapine\" width=\"1200\" height=\"850\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-6.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-6-565x400.jpg 565w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-6-1129x800.jpg 1129w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-6-768x544.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-6-350x248.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68120\" class=\"wp-caption-text\">Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Nevirapine<\/figcaption><\/figure>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Viramune XR, Viramune.<\/p>\n<p>T\u00ean th\u01b0\u01a1ng m\u1ea1i: Nevirapine STADA 200mg, Nevimum.<\/p>\n<h3>Thu\u1ed1c \u1ee9c ch\u1ebf Protease<\/h3>\n<h4>Indinavir<\/h4>\n<p>S\u1eed d\u1ee5ng k\u1ebft h\u1ee3p v\u1edbi thu\u1ed1c \u1ee9c ch\u1ebf enzym sao ch\u00e9p ng\u01b0\u1ee3c \u0111\u1ec3 k\u00e9o d\u00e0i th\u1eddi gian kh\u00e1ng thu\u1ed1c.<\/p>\n<p>Li\u1ec1u d\u00f9ng: U\u1ed1ng 800mg, c\u00e1ch 8 gi\u1edd u\u1ed1ng l\u1ea1i m\u1ed9t l\u1ea7n, n\u00ean u\u1ed1ng c\u00e1ch xa b\u1eefa \u0103n. C\u00e1c d\u1ea1ng vi\u00ean u\u1ed1ng 200mg, 400mg.<\/p>\n<h4>Ritonavir<\/h4>\n<p>\u1ee8c ch\u1ebf \u0111\u1eb7c hi\u1ec7u HIV-1 protease.<\/p>\n<p>C\u00f3 2 d\u1ea1ng b\u00e0o ch\u1ebf l\u00e0 d\u1ea1ng vi\u00ean nang 100mg v\u00e0 d\u1ea1ng dung d\u1ecbch u\u1ed1ng 80mg\/mL.<\/p>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Norvir, Norvir Soft Gelatin.<\/p>\n<p>T\u00ean th\u01b0\u01a1ng m\u1ea1i: Lopinavir\/Ritonavir 200mg\/50mg Mylan, Kaletra,&#8230;<\/p>\n<figure id=\"attachment_68121\" aria-describedby=\"caption-attachment-68121\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68121\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-7.jpg\" alt=\"Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Ritonavir\" width=\"1200\" height=\"850\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-7.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-7-565x400.jpg 565w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-7-1129x800.jpg 1129w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-7-768x544.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-7-350x248.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68121\" class=\"wp-caption-text\">Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Ritonavir<\/figcaption><\/figure>\n<h3>Nguy\u00ean t\u1eafc s\u1eed d\u1ee5ng thu\u1ed1c ch\u1ed1ng HIV<\/h3>\n<p>WHO \u0111\u01b0a ra khuy\u1ebfn c\u00e1o v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c ch\u1ed1ng HIV nh\u01b0 sau:<\/p>\n<ul>\n<li>AZT + 3 TC + Nevirapin.<\/li>\n<li>AZT + 3 TC + Nelfinavir.<\/li>\n<li>AZT + 3 TC + Lopinavir\/ indinavir\/ Saquinavir.<\/li>\n<\/ul>\n<p>Vi\u1ec7c s\u1eed d\u1ee5ng 2 thu\u1ed1c ch\u1ed1ng HIV \u0111\u01b0\u1ee3c coi l\u00e0 kh\u00f4ng c\u00f2n th\u00edch h\u1ee3p.<\/p>\n<p>Vi\u1ec7c tu\u00e2n th\u1ee7 nguy\u00ean t\u1eafc \u0111i\u1ec1u tr\u1ecb c\u00f3 \u00fd ngh\u0129a h\u01a1n vi\u1ec7c l\u1ef1a ch\u1ecdn thu\u1ed1c \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>\u0110\u1ed1i v\u1edbi tr\u1ebb em v\u00e0 ph\u1ee5 n\u1eef mang thai, c\u1ea7n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb ph\u1ed1i h\u1ee3p thu\u1ed1c t\u1ed1i \u01b0u.<\/p>\n<h2>Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb virus vi\u00eam gan<\/h2>\n<p>Virus vi\u00eam gan (hepatotropic virus) c\u00f3 th\u1ec3 g\u00e2y vi\u00eam v\u00e0 ho\u1ea1i t\u1eed gan.<\/p>\n<p>C\u00f3 5 lo\u1ea1i virus g\u00e2y b\u1ec7nh vi\u00eam gan bao g\u1ed3m:<\/p>\n<ul>\n<li>Hepatitis A (HAV).<\/li>\n<li>Hepatitis B (HBV).<\/li>\n<li>Hepatitis C (HCV).<\/li>\n<li>Hepatitis D (HDV).<\/li>\n<li>Hepatitis E (HEV).<\/li>\n<\/ul>\n<p>Trong \u0111\u00f3, Hepatitis D (HDV), Hepatitis E (HEV) l\u00e0 2 lo\u1ea1i \u00edt ph\u1ed5 bi\u1ebfn h\u01a1n.<\/p>\n<p>Vi\u00eam gan virus B v\u00e0 vi\u00eam gan virus C c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn x\u01a1 gan, suy gan, ung th\u01b0 gan. Do \u0111\u00f3, c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb vi\u00eam gan virus s\u1ebd \u0111\u1ec1 c\u1eadp ch\u1ee7 y\u1ebfu \u0111\u1ebfn vi\u00eam gan virus B v\u00e0 vi\u00eam gan virus C.<\/p>\n<h3>Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb virus vi\u00eam gan B<\/h3>\n<p>C\u00e1c li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb virus vi\u00eam gan B hi\u1ec7n nay kh\u00f4ng th\u1ec3 ch\u1eefa kh\u1ecfi ho\u00e0n to\u00e0n v\u00e0 ch\u1ec9 d\u01b0\u1edbi 10% b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c ch\u1eefa kh\u1ecfi v\u1ec1 m\u1eb7t ch\u1ee9c n\u0103ng.<\/p>\n<h4>Adefovir Dipivoxil (PMEA)<\/h4>\n<figure id=\"attachment_68122\" aria-describedby=\"caption-attachment-68122\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68122\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-8.jpg\" alt=\"Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Adefovir Dipivoxil (PMEA)\" width=\"1200\" height=\"850\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-8.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-8-565x400.jpg 565w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-8-1129x800.jpg 1129w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-8-768x544.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-8-350x248.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68122\" class=\"wp-caption-text\">Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Adefovir Dipivoxil (PMEA)<\/figcaption><\/figure>\n<p>Adefovir Dipivoxil (PMEA) l\u00e0 d\u1ea1ng ti\u1ec1n thu\u1ed1c c\u1ee7a adefovir. PMEA ho\u1ea1t \u0111\u1ed9ng t\u01b0\u01a1ng t\u1ef1 nh\u01b0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf c\u1ea1nh tranh v\u1edbi ADN polymerase HBV, t\u1eeb \u0111\u00f3 PMEA t\u00edch h\u1ee3p v\u00e0o ADN c\u1ee7a virus d\u1eabn \u0111\u1ebfn k\u1ebft th\u00fac chu\u1ed7i ADN.<\/p>\n<p>Adefovir Dipivoxil (PMEA) l\u00e0 thu\u1ed1c c\u00f3 \u00e1i l\u1ef1c cao v\u1edbi ADN polymerase c\u1ee7a virus vi\u00eam gan B.<\/p>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Hepsera.<\/p>\n<p>T\u00ean th\u01b0\u01a1ng m\u1ea1i: Adefovir STADA.<\/p>\n<h4>Entecavir<\/h4>\n<figure id=\"attachment_68123\" aria-describedby=\"caption-attachment-68123\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68123\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-9.jpg\" alt=\"Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Entecavir\" width=\"1200\" height=\"850\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-9.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-9-565x400.jpg 565w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-9-1129x800.jpg 1129w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-9-768x544.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-9-350x248.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68123\" class=\"wp-caption-text\">Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Entecavir<\/figcaption><\/figure>\n<p>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a Entecavir l\u00e0 \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p ADN c\u1ee7a virus vi\u00eam gan B.<\/p>\n<p>Entecavir c\u00f3 b\u1ea3n ch\u1ea5t t\u01b0\u01a1ng t\u1ef1 nh\u01b0 guanosin.<\/p>\n<p>Sau khi v\u00e0o c\u01a1 th\u1ec3, Entecavir ph\u1ea3i tr\u1ea3i qua qu\u00e1 tr\u00ecnh phosphoryl h\u00f3a n\u1ed9i b\u00e0o \u0111\u1ec3 t\u1ea1o th\u00e0nh ch\u1ea5t c\u00f3 ho\u1ea1t t\u00ednh l\u00e0 Entecavir triphosphat. Ch\u1ea5t n\u00e0y \u1ee9c ch\u1ebf c\u1ea3 3 ho\u1ea1t \u0111\u1ed9ng c\u1ee7a virus vi\u00eam gan B bao g\u1ed3m:<\/p>\n<p>C\u1ea1nh tranh v\u1edbi deoxyguanosine triphosphat \u0111\u1ec3 t\u00edch h\u1ee3p v\u00e0o ADN c\u1ee7a virus vi\u00eam gan B.<\/p>\n<p>\u1ee8c ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a HBV polymerase.<\/p>\n<p>Nh\u00f3m 3\u2019-hydroxy c\u1ee7a entecavir t\u00edch h\u1ee3p v\u00e0o ADN tr\u01b0\u1edbc khi d\u1eebng ho\u1ea1t \u0111\u1ed9ng c\u1ee7a ADN polymerase v\u00e0 c\u00e1c nucleotit kh\u00e1c.<\/p>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Baraclude.<\/p>\n<p>T\u00ean th\u01b0\u01a1ng m\u1ea1i: Entecavir Stella, A.T Entecavir 0.5,&#8230;<\/p>\n<h4>Telbivudine<\/h4>\n<figure id=\"attachment_68124\" aria-describedby=\"caption-attachment-68124\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68124\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-90.jpg\" alt=\"Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Telbivudine\" width=\"1200\" height=\"850\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-90.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-90-565x400.jpg 565w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-90-1129x800.jpg 1129w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-90-768x544.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-90-350x248.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68124\" class=\"wp-caption-text\">Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Telbivudine<\/figcaption><\/figure>\n<p>Telbivudine sau khi v\u00e0o c\u01a1 th\u1ec3 s\u1ebd \u0111\u01b0\u1ee3c phosphoryl h\u00f3a \u0111\u1ec3 t\u1ea1o th\u00e0nh d\u1ea1ng triphosphat ho\u1ea1t \u0111\u1ed9ng nh\u1edd c\u00e1c kinase c\u1ee7a t\u1ebf b\u00e0o.<\/p>\n<p>Telbivudine 5\u2032-triphosphate c\u1ea1nh tranh v\u1edbi thymidine 5\u2019-triphosphate t\u1eeb \u0111\u00f3 \u1ee9c ch\u1ebf ADN polymerase HBV t\u1eeb \u0111\u00f3 l\u00e0m k\u1ebft th\u00fac qu\u00e1 tr\u00ecnh k\u00e9o d\u00e0i chu\u1ed7i c\u1ee7a virus.<\/p>\n<p>Telbivudine \u01b0u ti\u00ean \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p chu\u1ed7i ADN th\u1ee9 hai h\u01a1n so v\u1edbi chu\u1ed7i ADN \u0111\u1ea7u ti\u00ean.<\/p>\n<p>Thu\u1ed1c c\u00f3 ho\u1ea1t t\u00ednh \u0111\u1ed1i v\u1edbi hepa ADN nh\u01b0ng l\u1ea1i kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh \u0111\u1ed1i v\u1edbi virus kh\u00e1c.<\/p>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Tyzeka.<\/p>\n<p>T\u00ean th\u01b0\u01a1ng m\u1ea1i: Sebivo.<\/p>\n<h4>Lamivudin<\/h4>\n<figure id=\"attachment_68125\" aria-describedby=\"caption-attachment-68125\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68125\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-91.jpg\" alt=\"Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Lamivudin\" width=\"1200\" height=\"850\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-91.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-91-565x400.jpg 565w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-91-1129x800.jpg 1129w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-91-768x544.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-91-350x248.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68125\" class=\"wp-caption-text\">Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Lamivudin<\/figcaption><\/figure>\n<p>Lamivudin c\u00f3 c\u1ea5u tr\u00fac t\u01b0\u01a1ng t\u1ef1 v\u1edbi Zalcitabine. Sau khi v\u00e0o c\u01a1 th\u1ec3, thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n th\u00e0nh d\u1ea1ng lamivudin-5\u2019-triphosphat (3TC-TP) c\u00f3 ho\u1ea1t t\u00ednh. C\u01a1 ch\u1ebf stacs d\u1ee5ng c\u1ee7a thu\u1ed1c l\u00e0 c\u1ea1nh tranh v\u1edbi deoxycytidine triphosphate t\u1ef1 nhi\u00ean t\u1eeb \u0111\u00f3 l\u00e0m gi\u1ea3m s\u1ef1 t\u1ed5ng h\u1ee3p ADN c\u1ee7a t\u1ebf b\u00e0o.<\/p>\n<p>Lamivudin c\u00f3 \u0111\u1ed9c t\u00ednh th\u1ea5p \u0111\u1ed1i v\u1edbi t\u1ebf b\u00e0o.<\/p>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Epivir, Epivir HBV.<\/p>\n<p>T\u00ean th\u01b0\u01a1ng m\u1ea1i: Lamivudin Stella, SaVi Lamivudin,&#8230;<\/p>\n<h4>Tenofovir<\/h4>\n<figure id=\"attachment_68126\" aria-describedby=\"caption-attachment-68126\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68126\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-92.jpg\" alt=\"Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Tenofovir\" width=\"1200\" height=\"850\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-92.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-92-565x400.jpg 565w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-92-1129x800.jpg 1129w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-92-768x544.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-92-350x248.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68126\" class=\"wp-caption-text\">Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Tenofovir<\/figcaption><\/figure>\n<p>Tenofovir th\u01b0\u1eddng \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf \u1edf d\u1ea1ng ti\u1ec1n ch\u1ea5t. Sau khi v\u00e0o c\u01a1 th\u1ec3, s\u1ebd tr\u1ea3i qua qu\u00e1 tr\u00ecnh phosphoryl h\u00f3a \u0111\u1ec3 chuy\u1ec3n th\u00e0nh d\u1ea1ng c\u00f3 ho\u1ea1t t\u00ednh l\u00e0 Tenofovir diphosphat.<\/p>\n<p>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c l\u00e0 \u1ee9c ch\u1ebf enzym polymerase c\u1ee7a ADN virus vi\u00eam gan B khi\u1ebfn ch\u00fang kh\u00f4ng th\u1ec3 nh\u00e2n l\u00ean.<\/p>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Vemlidy, Viread.<\/p>\n<p>T\u00ean th\u01b0\u01a1ng m\u1ea1i: SaVi Tenofovir 300, Tenofovir 300 STADA,&#8230;<\/p>\n<h3>Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb vi\u00eam gan virus C<\/h3>\n<p>C\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb vi\u00eam gan virus C \u0111\u01b0\u1ee3c chia th\u00e0nh 2 nh\u00f3m:<\/p>\n<ul>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf protease HCV NS3, NS4A.<\/li>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf protease HCV NS5A, NS5B.<\/li>\n<\/ul>\n<p>Nh\u1eefng n\u0103m tr\u01b0\u1edbc \u0111\u00e2y, vi\u00eam gan virus C \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng ph\u00e1c \u0111\u1ed3 ti\u00eam thu\u1ed1c d\u01b0\u1edbi da. Tuy nhi\u00ean, t\u1ef7 l\u1ec7 \u0111\u00e1p \u1ee9ng th\u1ea5p v\u00e0 kh\u1ea3 n\u0103ng dung n\u1ea1p thu\u1ed1c k\u00e9m.<\/p>\n<p>Hi\u1ec7n nay, c\u00f3 m\u1ed9t s\u1ed1 thu\u1ed1c kh\u00e1ng virus \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf nh\u1eb1m m\u1ee5c ti\u00eau t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn c\u00e1c giai \u0111o\u1ea1n kh\u00e1c nhau trong v\u00f2ng \u0111\u1eddi c\u1ee7a virus vi\u00eam gan C. Nh\u00f3m thu\u1ed1c n\u00e0y \u0111\u01b0\u1ee3c vi\u1ebft t\u1eaft l\u00e0 DAA (direct acting antivirus). DAA \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nhi\u1ec1u trong c\u00e1c li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb vi\u00eam gan virus C.<\/p>\n<p>\u01afu \u0111i\u1ec3m c\u1ee7a c\u00e1c DAA l\u00e0 \u00edt t\u00e1c d\u1ee5ng ph\u1ee5, b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng thu\u1ed1c theo \u0111\u01b0\u1eddng u\u1ed1ng, th\u1eddi gian \u0111i\u1ec1u tr\u1ecb th\u01b0\u1eddng l\u00e0 8,12 ho\u1eb7c 24 tu\u1ea7n. T\u1ef7 l\u1ec7 \u0111i\u1ec1u tr\u1ecb th\u00e0nh c\u00f4ng l\u00e0 h\u01a1n 90%.<\/p>\n<p>Hi\u1ec7n nay, DAA \u0111\u00e3 thay th\u1ebf pegIFN-a \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb vi\u00eam gan virus C. Tuy nhi\u00ean, Ribavirin v\u1eabn \u0111\u01b0\u1ee3c k\u1ebft h\u1ee3p c\u00f9ng v\u1edbi DAA trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p nh\u1ea5t \u0111\u1ecbnh \u0111\u1ec3 c\u1ea3i thi\u1ec7n t\u1ef7 l\u1ec7 \u0111\u00e1p \u1ee9ng v\u1edbi li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h3>Ribavirin<\/h3>\n<figure id=\"attachment_68127\" aria-describedby=\"caption-attachment-68127\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68127\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-93.jpg\" alt=\"Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Ribavirin\" width=\"1200\" height=\"850\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-93.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-93-565x400.jpg 565w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-93-1129x800.jpg 1129w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-93-768x544.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-93-350x248.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68127\" class=\"wp-caption-text\">Ch\u1ebf ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng ch\u1ee9a Ribavirin<\/figcaption><\/figure>\n<p>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c l\u00e0 ng\u0103n c\u1ea3n qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p ARN v\u00e0 ADN t\u1eeb \u0111\u00f3 \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p protein v\u00e0 qu\u00e1 tr\u00ecnh nh\u00e2n l\u00ean c\u1ee7a virus.<br \/>\nRibavirin \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p v\u1edbi thu\u1ed1c kh\u00e1ng virus t\u00e1c \u0111\u1ed9ng tr\u1ef1c ti\u1ebfp (DAA) trong ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb vi\u00eam gan virus C.<\/p>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Copegus, Moderiba, RibaPak, RibaTab.<\/p>\n<p>T\u00ean th\u01b0\u01a1ng m\u1ea1i: Ribarin 400, Vixbarin 500, Ribatagin 500,&#8230;<\/p>\n<h3>Thu\u1ed1c \u1ee9c ch\u1ebf NS3\/4A protease<\/h3>\n<h4>Boceprevir<\/h4>\n<p>Boceprevir v\u00e0 simeprevir ho\u1eb7c paritaprevir l\u00e0 nh\u1eefng ch\u1ea5t \u0111\u1ea1i di\u1ec7n cho nh\u00f3m thu\u1ed1c \u1ee9c ch\u1ebf NS3\/4A protease.<\/p>\n<p>Boceprevir li\u00ean k\u1ebft thu\u1eadn ngh\u1ecbch v\u1edbi NS3\/4A, s\u1ef1 \u1ee9c ch\u1ebf gi\u00fap ng\u0103n c\u1ea3n qu\u00e1 tr\u00ecnh sao ch\u00e9p b\u1ed9 gen ARN c\u1ee7a HCV.<\/p>\n<p>T\u1ef7 l\u1ec7 li\u00ean k\u1ebft v\u1edbi protein c\u1ee7a Boceprevir l\u00e0 68%.<\/p>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Victrelis.<\/p>\n<h4>Simeprevir<\/h4>\n<p>Simeprevir c\u00f3 c\u1ea5u tr\u00fac v\u00f2ng 14 c\u1ea1nh, thu\u1ed1c li\u00ean k\u1ebft v\u1edbi c\u00e1c cetoacid b\u1eb1ng li\u00ean k\u1ebft c\u1ed9ng h\u00f3a tr\u1ecb.<\/p>\n<p>Sinh kh\u1ea3 d\u1ee5ng c\u1ee7a Simeprevir l\u00e0 62%, n\u00ean u\u1ed1ng thu\u1ed1c c\u00f9ng b\u1eefa \u0103n do sinh kh\u1ea3 d\u1ee5ng c\u1ee7a Simeprevir t\u0103ng l\u00ean khi c\u00f3 m\u1eb7t th\u1ee9c \u0103n.<\/p>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Olysio.<\/p>\n<h3>Thu\u1ed1c \u1ee9c ch\u1ebf NS5A\/5B protease<\/h3>\n<h4>Sofosbuvir<\/h4>\n<p>Sofosbuvir l\u00e0 d\u1ea1ng ti\u1ec1n ch\u1ea5t, thu\u1ed1c c\u00f3 c\u1ea5u tr\u00fac c\u1ee7a nucleoside. \u1ede trong t\u1ebf b\u00e0o, Sofosbuvir s\u1ebd \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a th\u00e0nh d\u1ea1ng ho\u1ea1t \u0111\u1ed9ng. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c l\u00e0 \u1ee9c ch\u1ebf ARN polymerase c\u1ee7a HCV. B\u00ean c\u1ea1nh \u0111\u00f3, thu\u1ed1c c\u0169ng c\u00f3 th\u1ec3 ho\u1ea1t \u0111\u1ed9ng t\u01b0\u01a1ng t\u1ef1 nh\u01b0 m\u1ed9t ch\u1ea5t k\u1ebft th\u00fac s\u1ef1 k\u00e9o d\u00e0i chu\u1ed7i.<\/p>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Sovaldi.<\/p>\n<h4>Ombitasvir, ledipasvir, dasabuvir<\/h4>\n<p>Ombitasvir v\u00e0 Ledipasvir c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf NS5A.<\/p>\n<p>Dasabuvir c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf NS5B.<\/p>\n<p>Ledipasvir th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng c\u00f9ng v\u1edbi Sofosbuvir.<\/p>\n<h2>Thu\u1ed1c ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb c\u00fam<\/h2>\n<p>B\u1ec7nh c\u00fam g\u00e2y ra b\u1edfi c\u00e1c lo\u1ea1i virus c\u00f3 b\u1ed9 gen ARN s\u1ee3i \u0111\u01a1n \u00e2m.<\/p>\n<p>C\u00f3 3 lo\u1ea1i virus c\u00fam \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh l\u00e0 A, B v\u00e0 C.<\/p>\n<p>Hi\u1ec7n nay, c\u00f3 5 lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c ph\u00ea duy\u1ec7t \u0111\u1ec3 ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb c\u00fam, bao g\u1ed3m:<\/p>\n<ul>\n<li>Amantadin.<\/li>\n<li>Rimantadine.<\/li>\n<li>Oseltamivir.<\/li>\n<li>Zanamivir.<\/li>\n<li>Peramivir<\/li>\n<\/ul>\n<h3>Amantadine v\u00e0 Rimantadine<\/h3>\n<p>Amantadine v\u00e0 rimantadine \u1ee9c ch\u1ebf giai \u0111o\u1ea1n \u0111\u1ea7u ti\u00ean trong qu\u00e1 tr\u00ecnh nh\u00e2n l\u00ean c\u1ee7a virus th\u00f4ng qua vi\u1ec7c ng\u0103n c\u1ea3n s\u1ef1 c\u1edfi \u00e1o c\u1ee7a b\u1ed9 gen virus, chuy\u1ec3n acid nucleic v\u00e0o trong t\u1ebf b\u00e0o c\u1ee7a v\u1eadt ch\u1ee7.<\/p>\n<p>Tuy nhi\u00ean, vi\u1ec7c s\u1eed d\u1ee5ng Amantadine gi\u1ea3m \u0111\u00e1ng k\u1ec3, \u0111\u1ed3ng th\u1eddi vi\u1ec7c s\u1eed d\u1ee5ng Rimantadine ng\u00e0y c\u00e0ng b\u1ecb gi\u1edbi h\u1ea1n.<\/p>\n<h3>C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf neuraminidase (Zanamivir, Oseltamivir v\u00e0 Peramivir)<\/h3>\n<figure id=\"attachment_68128\" aria-describedby=\"caption-attachment-68128\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68128\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-94.jpg\" alt=\"Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb c\u00fam\" width=\"1200\" height=\"850\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-94.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-94-565x400.jpg 565w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-94-1129x800.jpg 1129w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-94-768x544.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-94-350x248.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68128\" class=\"wp-caption-text\">Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb c\u00fam<\/figcaption><\/figure>\n<p>Neuraminidase \u0111\u00f3ng m\u1ed9t vai tr\u00f2 quan tr\u1ecdng trong qu\u00e1 tr\u00ecnh ho\u1ea1t h\u00f3a c\u00e1c virus m\u1edbi. N\u1ebfu kh\u00f4ng c\u00f3 Neuraminidase, virus c\u00fam kh\u00f4ng th\u1ec3 gi\u1ea3i ph\u00f3ng \u0111\u01b0\u1ee3c ra kh\u1ecfi nh\u1eefng t\u1ebf b\u00e0o nhi\u1ec5m b\u1ec7nh, do \u0111\u00f3 vi\u1ec7c ph\u00e1t tri\u1ec3n c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf neuraminidase ng\u00e0y c\u00e0ng \u0111\u01b0\u1ee3c quan t\u00e2m.<\/p>\n<h4>Zanamivir<\/h4>\n<p>Zanamivir l\u00e0 d\u1eabn ch\u1ea5t c\u1ee7a acid sialic, thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng v\u1edbi \u0111a s\u1ed1 c\u00e1c ch\u1ee7ng c\u00fam A v\u00e0 c\u00fam B, bao g\u1ed3m c\u1ea3 nh\u1eefng ch\u1ee7ng \u0111\u00e3 kh\u00e1ng v\u1edbi Oseltamivir, Rimantadine, Amantadine.<\/p>\n<p>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c l\u00e0 \u1ee9c ch\u1ebf c\u1ea1nh tranh v\u00e0 ch\u1ecdn l\u1ecdc v\u1edbi enzyme neuraminidase t\u1eeb \u0111\u00f3 t\u00e1c \u0111\u1ed9ng tr\u1ef1c ti\u1ebfp l\u00ean qu\u00e1 tr\u00ecnh nh\u00e2n l\u00ean c\u1ee7a virus.<\/p>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Relenza.<\/p>\n<h4>Oseltamivir<\/h4>\n<p>Oseltamivir c\u00f3 b\u1ea3n ch\u1ea5t l\u00e0 m\u1ed9t ti\u1ec1n ch\u1ea5t, sau khi v\u00e0o c\u01a1 th\u1ec3 s\u1ebd \u0111\u01b0\u1ee3c th\u1ee7y ph\u00e2n t\u1ea1o th\u00e0nh oseltamivir carboxylate &#8211; ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh.<\/p>\n<p>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a Oseltamivir carboxylate l\u00e0 \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc enzyme neuraminidase t\u1eeb \u0111\u00f3 ng\u0103n c\u1ea3n s\u1ef1 gi\u1ea3i ph\u00f3ng c\u00e1c h\u1ea1t virus c\u00fam m\u1edbi, h\u1ea1n ch\u1ebf s\u1ef1 x\u00e2m nh\u1eadp v\u00e0 ph\u00e1t t\u00e1n b\u1ec7nh.<\/p>\n<p>C\u00e1c nghi\u00ean c\u1ee9u in vitro cho th\u1ea5y, Oseltamivir c\u00f3 t\u00e1c d\u1ee5ng t\u1ed1t tr\u00ean c\u1ea3 virus c\u00fam A v\u00e0 c\u00fam B, thu\u1ed1c c\u0169ng c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ed1i v\u1edbi virus c\u00fam gia c\u1ea7m type A.<\/p>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Tamiflu.<\/p>\n<p>T\u00ean th\u01b0\u01a1ng m\u1ea1i: Oseltamivir, Flustad 75,&#8230;.<\/p>\n<h4>Peramivir<\/h4>\n<p>Peramivir \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00fam cho ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 2 tu\u1ed5i tr\u1edf l\u00ean \u0111\u00e3 c\u00f3 c\u00e1c tri\u1ec7u ch\u1ee9ng c\u00fam trong t\u1ed1i \u0111a 2 ng\u00e0y.<\/p>\n<p>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c l\u00e0 ng\u0103n ch\u1eb7n enzym trong c\u01a1 th\u1ec3 gi\u1ea3i ph\u00f3ng virus t\u1eeb c\u00e1c t\u1ebf b\u00e0o nhi\u1ec5m b\u1ec7nh.<\/p>\n<p>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Rapivab.<\/p>\n<h2>Thu\u1ed1c kh\u00e1ng virus Covid-19<\/h2>\n<p>S\u1eed d\u1ee5ng thu\u1ed1c kh\u00e1ng virus cho b\u1ec7nh nh\u00e2n m\u1ee9c \u0111\u1ed9 nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh, n\u00ean s\u1eed d\u1ee5ng thu\u1ed1c trong giai \u0111o\u1ea1n virus \u0111ang nh\u00e2n l\u00ean \u0111\u1ed3ng th\u1eddi c\u1ea7n gi\u1ea3m t\u1ea3i s\u1ed1 l\u01b0\u1ee3ng virus c\u00f3 trong c\u01a1 th\u1ec3.<\/p>\n<p>2 nh\u00f3m thu\u1ed1c s\u1eed d\u1ee5ng trong ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb Covid-19 bao g\u1ed3m:<\/p>\n<ul>\n<li>Thu\u1ed1c kh\u00e1ng virus ph\u1ed5 r\u1ed9ng (Molnupiravir, Favipiravir, Remdesivir).<\/li>\n<li>Kh\u00e1ng th\u1ec3 \u0111\u01a1n d\u00f2ng \u0111\u1eb7c hi\u1ec7u v\u1edbi virus SARS-CoV-2.<\/li>\n<\/ul>\n<h3>Thu\u1ed1c kh\u00e1ng virus ph\u1ed5 r\u1ed9ng<\/h3>\n<h4>Thu\u1ed1c kh\u00e1ng Covid Molnupiravir<\/h4>\n<figure id=\"attachment_68129\" aria-describedby=\"caption-attachment-68129\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-68129\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-95.jpg\" alt=\"Thu\u1ed1c kh\u00e1ng Covid Molnupiravir\" width=\"1200\" height=\"528\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-95.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-95-800x352.jpg 800w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-95-768x338.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2024\/03\/thuoc-khang-virus-95-350x154.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-68129\" class=\"wp-caption-text\">Thu\u1ed1c kh\u00e1ng Covid Molnupiravir<\/figcaption><\/figure>\n<p>Molnupiravir \u0111\u00e3 \u0111\u01b0\u1ee3c FDA ph\u00ea duy\u1ec7t \u0111\u1ec3 s\u1eed d\u1ee5ng kh\u1ea9n c\u1ea5p cho b\u1ec7nh nh\u00e2n Covid-19 m\u1ee9c \u0111\u1ed9 nh\u1eb9.<\/p>\n<p>Li\u1ec1u d\u00f9ng: M\u1ed7i l\u1ea7n u\u1ed1ng 800mg, ng\u00e0y u\u1ed1ng 2 l\u1ea7n. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb l\u00e0 5 ng\u00e0y.<\/p>\n<h4>Favipiravir<\/h4>\n<p>Favipiravir \u0111ang \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb Covid-19, c\u00e1c d\u1eef li\u1ec7u v\u1ec1 hi\u1ec7u qu\u1ea3 v\u00e0 \u0111\u1ed9 an to\u00e0n c\u1ee7a thu\u1ed1c c\u00f2n h\u1ea1n ch\u1ebf.<\/p>\n<p>Li\u1ec1u d\u00f9ng: M\u1ed7i l\u1ea7n u\u1ed1ng 800mg, ng\u00e0y u\u1ed1ng 2 l\u1ea7n. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb l\u00e0 5 ng\u00e0y.<\/p>\n<h4>Remdesivir<\/h4>\n<p>L\u00e0 thu\u1ed1c duy nh\u1ea5t \u0111\u01b0\u1ee3c FDA ph\u00ea duy\u1ec7t \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb Covid-19.<\/p>\n<p>Remdesivir \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh nh\u00e2n n\u1ed9i tr\u00fa, suy h\u00f4 h\u1ea5p ph\u1ea3i th\u1edf oxy v\u1edbi \u0111i\u1ec1u ki\u1ec7n kh\u1edfi ph\u00e1t b\u1ec7nh ch\u01b0a qu\u00e1 10 ng\u00e0y. Tuy nhi\u00ean, kh\u00f4ng s\u1eed d\u1ee5ng Remdesivir \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb \u0111\u01a1n \u0111\u1ed9c m\u00e0 c\u1ea7n k\u1ebft h\u1ee3p v\u1edbi corticoid (\u01b0u ti\u00ean s\u1eed d\u1ee5ng dexamethasone).<\/p>\n<p>Li\u1ec1u d\u00f9ng:<\/p>\n<ul>\n<li>Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em tr\u00ean 12 tu\u1ed5i v\u00e0 c\u00e2n n\u1eb7ng tr\u00ean 40kg: Ng\u00e0y \u0111\u1ea7u ti\u00ean s\u1eed d\u1ee5ng 200mg, nh\u1eefng ng\u00e0y sau d\u00f9ng 100mg, truy\u1ec1n t\u0129nh m\u1ea1ch 1 l\u1ea7n trong 30-120 ph\u00fat.<\/li>\n<li>Tr\u1ebb em d\u01b0\u1edbi 12 tu\u1ed5i, c\u00e2n n\u1eb7ng t\u1eeb 3,5 \u0111\u1ebfn 40kg: Ng\u00e0y \u0111\u1ea7u ti\u00ean s\u1eed d\u1ee5ng 5mg\/kg c\u00e2n n\u1eb7ng, c\u00e1c ng\u00e0y sau 2,5mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch 1 l\u1ea7n trong 30-120 ph\u00fat.<\/li>\n<li>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb l\u00e0 5 ng\u00e0y.<\/li>\n<\/ul>\n<h3>Kh\u00e1ng th\u1ec3 \u0111\u01a1n d\u00f2ng \u0111\u1eb7c hi\u1ec7u v\u1edbi virus SARS-CoV-2<\/h3>\n<h4>Casirivimad + Imdevimad<\/h4>\n<p>\u0110\u01b0\u1ee3c FDA duy\u1ec7t \u0111\u1ec3 s\u1eed d\u1ee5ng kh\u1ea9n c\u1ea5p trong \u0111i\u1ec1u tr\u1ecb Covid-19.<\/p>\n<p>Ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng cho b\u1ec7nh nh\u00e2n kh\u1edfi ph\u00e1t b\u1ec7nh d\u01b0\u1edbi 10 ng\u00e0y, m\u1ee9c \u0111\u1ed9 b\u1ec7nh nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh nh\u01b0ng c\u00f3 nguy c\u01a1 ti\u1ebfn tri\u1ec3n l\u00ean m\u1ee9c \u0111\u1ed9 n\u1eb7ng.<\/p>\n<p>Li\u1ec1u l\u01b0\u1ee3ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o l\u00e0 600mg Casirivimad + 600mg Imdevimad, truy\u1ec1n t\u0129nh m\u1ea1ch 1 l\u1ea7n trong 30 ph\u00fat, d\u00f9ng li\u1ec1u duy nh\u1ea5t.<\/p>\n<h4>Bamlanivimad + Etesevimad<\/h4>\n<p>\u0110\u01b0\u1ee3c FDA duy\u1ec7t \u0111\u1ec3 s\u1eed d\u1ee5ng kh\u1ea9n c\u1ea5p trong \u0111i\u1ec1u tr\u1ecb Covid-19.<\/p>\n<h2>C\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng b\u1ec7nh do virus<\/h2>\n<p>Hi\u1ec7n nay, vi\u1ec7c s\u1eed d\u1ee5ng vacxin l\u00e0 bi\u1ec7n ph\u00e1p ph\u00f2ng b\u1ec7nh h\u1eefu hi\u1ec7u nh\u1ea5t, ng\u0103n ng\u1eeba s\u1ef1 t\u1ea5n c\u00f4ng c\u1ee7a virus. B\u00ean c\u1ea1nh \u0111\u00f3, c\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng b\u1ec7nh kh\u00f4ng \u0111\u1eb7c hi\u1ec7u c\u1ea7n \u0111\u01b0\u1ee3c l\u01b0u \u00fd bao g\u1ed3m:<\/p>\n<ul>\n<li>Ch\u1ee7 \u0111\u1ed9ng kh\u00e1m v\u00e0 x\u00e9t nghi\u1ec7m khi th\u1ea5y c\u00f3 d\u1ea5u hi\u1ec7u b\u1ea5t th\u01b0\u1eddng.<\/li>\n<li>\u0110\u1ec3 h\u1ea1n ch\u1ebf t\u00ecnh tr\u1ea1ng l\u00e2y lan, c\u1ea7n c\u00e1ch ly v\u1edbi nh\u1eefng ng\u01b0\u1eddi xung quanh khi b\u1ea3n th\u00e2n \u0111\u00e3 m\u1eafc b\u1ec7nh.<\/li>\n<li>R\u1eeda tay b\u1eb1ng dung d\u1ecbch v\u1ec7 sinh chuy\u00ean d\u1ee5ng.<\/li>\n<li>V\u1ec7 sinh n\u01a1i \u1edf s\u1ea1ch s\u1ebd, th\u01b0\u1eddng xuy\u00ean.<\/li>\n<li>X\u00e2y d\u1ef1ng ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng v\u00e0 sinh ho\u1ea1t \u0111i\u1ec1u \u0111\u1ed9 \u0111\u1ec3 t\u0103ng c\u01b0\u1eddng s\u1ee9c \u0111\u1ec1 kh\u00e1ng cho c\u01a1 th\u1ec3.<\/li>\n<li>Kh\u00f4ng t\u1ef1 \u00fd s\u1eed d\u1ee5ng thu\u1ed1c khi ch\u01b0a c\u00f3 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129.<\/li>\n<\/ul>\n<h2>K\u1ebft lu\u1eadn<\/h2>\n<p>Virus l\u00e0 t\u00e1c nh\u00e2n g\u00e2y n\u00ean c\u00e1c b\u1ec7nh truy\u1ec1n nhi\u1ec5m cho c\u1ea3 con ng\u01b0\u1eddi v\u00e0 \u0111\u1ed9ng v\u1eadt. Do \u0111\u00f3, vi\u1ec7c ti\u00eam vacxin v\u00e0 \u00e1p d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p ph\u00f2ng<\/p>\n<p>b\u1ec7nh l\u00e0 bi\u1ec7n ph\u00e1p t\u1ed1i \u01b0u \u0111\u1ec3 ng\u0103n ng\u1eeba l\u00e2y nhi\u1ec5m.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>Ruben Vardanyan v\u00e0 c\u1ed9ng s\u1ef1 (Th\u1eddi gian ph\u00e1t h\u00e0nh 19 th\u00e1ng 2 n\u0103m 2016). <em>Antiviral Drugs<\/em>. Truy c\u1eadp ng\u00e0y 7 th\u00e1ng 3 n\u0103m 2024 t\u1eeb <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7149618\/\" rel=\"noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7149618\/\u00a0<\/a><\/li>\n<li>Gandhi R. T. (Th\u1eddi gian ph\u00e1t h\u00e0nh n\u0103m 2021). <em>The Multidimensional Challenge of Treating Coronavirus Disease 2019 (COVID-19): Remdesivir Is a Foot in the Door. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America<\/em>, trang e4175\u2013e4178. Truy c\u1eadp ng\u00e0y 7 th\u00e1ng 3 n\u0103m 2024 t\u1eeb <a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa1132\" rel=\"noopener\">https:\/\/doi.org\/10.1093\/cid\/ciaa1132<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Virus l\u00e0 nh\u1eefng sinh v\u1eadt nh\u1ecf, c\u00f3 th\u1ec3 g\u00e2y ra nhi\u1ec1u lo\u1ea1i b\u1ec7nh nguy hi\u1ec3m \u0111\u1ed1i v\u1edbi con ng\u01b0\u1eddi. V\u1eady, thu\u1ed1c kh\u00e1ng virus l\u00e0 g\u00ec? B\u00e0i vi\u1ebft d\u01b0\u1edbi \u0111\u00e2y, D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng s\u1ebd cung c\u1ea5p cho b\u1ea1n \u0111\u1ecdc nh\u1eefng th\u00f4ng tin chi ti\u1ebft v\u1ec1 c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1ng virus hi\u1ec7n nay Virus l\u00e0 [&#8230;]\n","protected":false},"author":1,"featured_media":68113,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-68112","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/68112","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=68112"}],"version-history":[{"count":3,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/68112\/revisions"}],"predecessor-version":[{"id":72447,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/68112\/revisions\/72447"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/68113"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=68112"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=68112"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=68112"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}