B\u00e1c s\u0129 L\u00ea Kh\u1eafc Ti\u1ebfn \u2013 BV M\u1ef9 \u0110\u1ee9c<\/p>\n
T\u1ea7n su\u1ea5t b\u00e9o ph\u00ec gia t\u0103ng l\u00e0 nguy\u00ean nh\u00e2n ch\u00ednh g\u00e2y ra c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 s\u1ee9c kh\u1ecfe. M\u1ed9t kh\u1ea3o s\u00e1t g\u1ea7n \u0111\u00e2y t\u1ea1i Anh qu\u1ed1c cho th\u1ea5y \u00bc d\u00e2n s\u1ed1 n\u01b0\u1edbc n\u00e0y \u0111ang trong t\u00ecnh tr\u1ea1ng b\u00e9o ph\u00ec (\u1edf nam l\u00e0 23.6% v\u00e0 n\u1eef l\u00e0 23.8%), v\u1edbi ch\u1ec9 s\u1ed1 kh\u1ed1i c\u01a1 th\u1ec3 l\u00e0 \u2265 30 kg\/m2. Nh\u00ecn chung, 50% s\u1ed1 ph\u1ee5 n\u1eef trong \u0111\u1ed9 tu\u1ed5i sinh s\u1ea3n ho\u1eb7c \u0111ang th\u1eeba c\u00e2n, ho\u1eb7c b\u00e9o ph\u00ec. C\u00f3 \u0111\u1ebfn 20 – 40% ph\u1ee5 n\u1eef t\u0103ng c\u00e2n nhi\u1ec1u h\u01a1n khuy\u1ebfn c\u00e1o trong th\u1eddi gian mang thai, khi\u1ebfn cho bi\u1ebfn ch\u1ee9ng \u1edf m\u1eb9 v\u00e0 con gia t\u0103ng, bao g\u1ed3m ti\u1ec1n s\u1ea3n gi\u1eadt, \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng thai k\u1ef3, nhi\u1ec5m tr\u00f9ng, huy\u1ebft kh\u1ed1i, m\u1ed5 l\u1ea5y thai, thai l\u01b0u, s\u1ea9y thai, sinh non, d\u1ecb t\u1eadt thai.<\/p>\n
C\u00e1c chuy\u00ean gia cho r\u1eb1ng ti\u1ec1n s\u1ea3n l\u00e0 kho\u1ea3ng th\u1eddi gian c\u1eeda s\u1ed5 c\u01a1 h\u1ed9i \u0111\u1ec3 can thi\u1ec7p v\u00e0o v\u1ea5n \u0111\u1ec1 c\u00e2n n\u1eb7ng c\u1ee7a b\u00e0 m\u1eb9 nh\u1eb1m \u0111\u01b0a \u0111\u1ebfn nh\u1eefng thay \u0111\u1ed5i h\u1ee9a h\u1eb9n cho thai k\u1ef3. M\u1ed9t trong s\u1ed1 nh\u1eefng can thi\u1ec7p tr\u00ean c\u00e2n n\u1eb7ng c\u1ee7a b\u00e0 m\u1eb9 l\u00e0 can thi\u1ec7p v\u00e0o ch\u1ebf \u0111\u1ed9 \u0103n v\u00e0\/ho\u1eb7c s\u1eed d\u1ee5ng men vi sinh. \u0110\u1ec3 l\u00e0m r\u00f5 li\u1ec7u ch\u1ebf \u0111\u1ed9 \u0103n v\u00e0 men vi sinh c\u00f3 t\u00e1c \u0111\u1ed9ng t\u00edch c\u1ef1c \u0111\u1ebfn k\u1ebft c\u1ee5c thai k\u1ef3, t\u00e1c gi\u1ea3 Okesene-Gafa v\u00e0 c\u00e1c c\u1ed9ng s\u1ef1 \u0111\u00e3 th\u1ef1c hi\u1ec7n m\u1ed9t th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng ng\u1eabu nhi\u00ean c\u00f3 nh\u00f3m ch\u1ee9ng (RCT) 2×2 \u1edf nh\u1eefng ph\u1ee5 n\u1eef BMI \u2265 30 kg\/m2, mang \u0111\u01a1n thai v\u00e0 kh\u00f4ng c\u00f3 \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng thai k\u1ef3 t\u1ea1i th\u1eddi \u0111i\u1ec3m th\u1ef1c hi\u1ec7n nghi\u00ean c\u1ee9u. Nh\u1eefng ph\u1ee5 n\u1eef tham gia nghi\u00ean c\u1ee9u mang thai trong kho\u1ea3ng tu\u1ea7n l\u1ec5 th\u1ee9 12 \u0111\u1ebfn 17 tu\u1ea7n 6 ng\u00e0y \u0111\u01b0\u1ee3c ng\u1eabu nhi\u00ean chia th\u00e0nh hai nh\u00f3m: Nh\u00f3m nh\u1eefng ph\u1ee5 n\u1eef c\u00f3 can thi\u1ec7p ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng (bao g\u1ed3m 4 bu\u1ed5i \u0111\u00e0o t\u1ea1o v\u1ec1 dinh d\u01b0\u1ee1ng thai k\u1ef3 do chuy\u00ean gia y t\u1ebf c\u1ed9ng \u0111\u1ed3ng h\u01b0\u1edbng d\u1eabn v\u00e0 nh\u1eafn tin h\u01b0\u1edbng d\u1eabn \u0111\u1ebfn l\u00fac sinh) ho\u1eb7c nh\u00f3m \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng th\u01b0\u1eddng xuy\u00ean. V\u1edbi vi\u00ean u\u1ed1ng b\u1ed5 sung, m\u1ed9t nh\u00f3m s\u1ebd \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng men vi sinh (g\u1ed3m Lactobacillus rhammosus v\u00e0 Bifidobacterium lactis BB12) v\u00e0 nh\u00f3m c\u00f2n l\u1ea1i s\u1eed d\u1ee5ng gi\u1ea3 d\u01b0\u1ee3c, cho t\u1edbi l\u00fac sinh. Ph\u00e2n t\u00edch d\u1eef li\u1ec7u thu \u0111\u01b0\u1ee3c d\u1ef1a tr\u00ean hi\u1ec7u ch\u1ec9nh BMI n\u1ec1n c\u1ee7a b\u00e0 m\u1eb9. K\u1ebft c\u1ee5c thai k\u1ef3 c\u0169ng \u0111\u01b0\u1ee3c hi\u1ec7u ch\u1ec9nh d\u1ef1a tr\u00ean s\u1eafc t\u1ed9c, gi\u1edbi t\u00ednh v\u00e0 tu\u1ed5i thai l\u00fac sinh.<\/p>\n
T\u1ed5ng c\u1ed9ng 230 ph\u1ee5 n\u1eef mang thai \u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn trong kho\u1ea3ng th\u1eddi gian th\u00e1ng 4\/2015 \u0111\u1ebfn 6\/2017, trong s\u1ed1 \u0111\u00f3 116 ph\u1ee5 n\u1eef thu\u1ed9c nh\u00f3m can thi\u1ec7p ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng, 114 ph\u1ee5 n\u1eef thu\u1ed9c nh\u00f3m t\u01b0 v\u1ea5n ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng th\u01b0\u1eddng xuy\u00ean, 155 ph\u1ee5 n\u1eef thu\u1ed9c nh\u00f3m s\u1eed d\u1ee5ng men vi sinh v\u00e0 115 \u1edf nh\u00f3m gi\u1ea3 d\u01b0\u1ee3c. C\u00e1c \u0111\u1eb7c \u0111i\u1ec3m nh\u00e2n kh\u1ea9u h\u1ecdc \u1edf c\u00e1c nh\u00f3m t\u01b0\u01a1ng t\u1ef1 nhau. K\u1ebft qu\u1ea3 cho th\u1ea5y kh\u00f4ng c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t gi\u1eefa hai nh\u00f3m: nh\u00f3m can thi\u1ec7p ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng v\u1edbi nh\u00f3m t\u01b0 v\u1ea5n ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng th\u01b0\u1eddng xuy\u00ean v\u1ec1 (a) t\u0103ng c\u00e2n qu\u00e1 m\u1ee9c trong thai k\u1ef3 – t\u01b0\u01a1ng \u1ee9ng hai nh\u00f3m l\u1ea7n l\u01b0\u1ee3t l\u00e0 79\/107 (73.8%) v\u00e0 90\/110 (81.8%) ho\u1eb7c (b) c\u00e2n n\u1eb7ng thai – t\u01b0\u01a1ng \u1ee9ng hai nh\u00f3m l\u1ea7n l\u01b0\u1ee3t l\u00e0 3.575 v\u00e0 3.612 gram, ch\u00eanh l\u1ec7ch trung b\u00ecnh hi\u1ec7u ch\u1ec9nh (adjusted mean difference \u2013 adjusted MD) l\u00e0 -24 g. C\u00e2n n\u1eb7ng t\u01b0\u01a1ng \u1ee9ng gi\u1eefa nh\u00f3m s\u1eed d\u1ee5ng men vi sinh v\u00e0 gi\u1ea3 d\u01b0\u1ee3c l\u00e0 3.685 g v\u00e0 3.504 g, ch\u00eanh l\u1ec7ch trung b\u00ecnh hi\u1ec7u ch\u1ec9nh 107 g. T\u1ed5ng c\u00e2n n\u1eb7ng t\u0103ng trong thai k\u1ef3 \u1edf nh\u00f3m can thi\u1ec7p ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng th\u1ea5p h\u01a1n \u1edf nh\u00f3m t\u01b0 v\u1ea5n ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng th\u01b0\u1eddng xuy\u00ean (9.4 so v\u1edbi 11.4 kg, ch\u00eanh l\u1ec7ch trung b\u00ecnh hi\u1ec7u ch\u1ec9nh l\u00e0 1,76 kg, KTC 95%: 0,03 \u2013 3,55). Ngo\u00e0i ra kh\u00f4ng c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t gi\u1eefa hai nh\u00f3m \u1edf c\u00e1c k\u1ebft c\u1ee5c thai k\u1ef3 \u1edf m\u1eb9 v\u00e0 con kh\u00e1c.<\/p>\n
M\u1eb7c d\u00f9 gi\u00e1o d\u1ee5c ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng v\u00e0 men vi sinh kh\u00f4ng l\u00e0m thay \u0111\u1ed5i s\u1ed1 c\u00e2n n\u1eb7ng t\u0103ng trong thai k\u1ef3 ho\u1eb7c c\u00e2n n\u1eb7ng thai nhi l\u00fac sinh, ph\u01b0\u01a1ng ph\u00e1p n\u00e0y c\u0169ng c\u00f3 li\u00ean quan \u0111\u1ebfn gi\u1ea3m t\u1ed5ng s\u1ed1 c\u00e2n \u1edf ph\u1ee5 n\u1eef mang thai, n\u1ebfu \u0111\u01b0\u1ee3c duy tr\u00ec li\u00ean t\u1ee5c, \u0111i\u1ec1u n\u00e0y r\u1ea5t c\u00f3 l\u1ee3i cho s\u1ee9c kh\u1ecfe c\u1ee7a b\u00e0 m\u1eb9 v\u00e0 thai nhi.<\/p>\n
Ngu\u1ed3n: Okesene-Gafa, K. A., Li, M., Mckinlay, C. J., Taylor, R. S., Rush, E. C., Wall, C. R., … & Crowther, C. A. (2019). Effect of antenatal dietary interventions in maternal obesity on pregnancy weight-gain and birthweight: Healthy Mums and Babies (HUMBA) randomized trial. American Journal of Obstetrics and Gynecology.<\/p>\n
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B\u00e1c s\u0129 L\u00ea Kh\u1eafc Ti\u1ebfn \u2013 BV M\u1ef9 \u0110\u1ee9c T\u1ea7n su\u1ea5t b\u00e9o ph\u00ec gia t\u0103ng l\u00e0 nguy\u00ean nh\u00e2n ch\u00ednh g\u00e2y ra c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 s\u1ee9c kh\u1ecfe. M\u1ed9t kh\u1ea3o s\u00e1t g\u1ea7n \u0111\u00e2y t\u1ea1i Anh qu\u1ed1c cho th\u1ea5y \u00bc d\u00e2n s\u1ed1 n\u01b0\u1edbc n\u00e0y \u0111ang trong t\u00ecnh tr\u1ea1ng b\u00e9o ph\u00ec (\u1edf nam l\u00e0 23.6% v\u00e0 n\u1eef l\u00e0 […]\n","protected":false},"author":1,"featured_media":5960,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-5959","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/5959","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=5959"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/5959\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/5960"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=5959"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=5959"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=5959"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}