{"id":5952,"date":"2019-04-02T14:01:53","date_gmt":"2019-04-02T07:01:53","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?p=5952"},"modified":"2019-04-02T14:01:53","modified_gmt":"2019-04-02T07:01:53","slug":"cap-nhat-tong-quan-he-thong-va-phan-tich-gop-cac-bien-phap-du-phong-sinh-non-phong-to-toan-man-hinh","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/cap-nhat-tong-quan-he-thong-va-phan-tich-gop-cac-bien-phap-du-phong-sinh-non-phong-to-toan-man-hinh\/","title":{"rendered":"C\u1eadp nh\u1eadt t\u1ed5ng quan h\u1ec7 th\u1ed1ng v\u00e0 ph\u00e2n t\u00edch g\u1ed9p c\u00e1c bi\u1ec7n ph\u00e1p d\u1ef1 ph\u00f2ng sinh non Ph\u00f3ng to to\u00e0n m\u00e0n h\u00ecnh"},"content":{"rendered":"<h2>M\u1ed7i n\u0103m, tr\u00ean to\u00e0n th\u1ebf gi\u1edbi c\u00f3 kho\u1ea3ng 15 tri\u1ec7u em b\u00e9 ch\u00e0o \u0111\u1eddi tr\u01b0\u1edbc 37 tu\u1ea7n.<\/h2>\n<p>S\u1ed1 tr\u1ebb t\u1eed vong v\u00ec sinh non v\u1eabn nhi\u1ec1u nh\u1ea5t trong nh\u1eefng nguy\u00ean nh\u00e2n g\u00e2y t\u1eed vong s\u01a1 sinh. V\u00ec v\u1eady, d\u1ef1 ph\u00f2ng sinh non hi\u1ec7n v\u1eabn \u0111ang l\u00e0 \u0111\u1ec1 t\u00e0i \u0111\u01b0\u1ee3c c\u00e1c nh\u00e0 l\u00e2m s\u00e0ng quan t\u00e2m nhi\u1ec1u nh\u1ea5t khi ngh\u0129 \u0111\u1ebfn sinh non.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-5953 aligncenter\" src=\"https:\/\/www.vnras.com\/drug\/wp-content\/uploads\/2019\/04\/sinh_non.jpg\" alt=\"sinh non \" width=\"450\" height=\"450\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2019\/04\/sinh_non.jpg 450w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2019\/04\/sinh_non-350x350.jpg 350w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2019\/04\/sinh_non-150x150.jpg 150w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2019\/04\/sinh_non-300x300.jpg 300w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2019\/04\/sinh_non-100x100.jpg 100w\" sizes=\"auto, (max-width: 450px) 100vw, 450px\" \/><\/p>\n<p>C\u00e1c bi\u1ec7n ph\u00e1p d\u1ef1 ph\u00f2ng sinh non hi\u1ec7n nay \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng tr\u00ean l\u00e2m s\u00e0ng bao g\u1ed3m: progesterone, kh\u00e2u v\u00f2ng c\u1ed5 t\u1eed cung, v\u00f2ng n\u00e2ng c\u1ed5 t\u1eed cung. Progesterone l\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111a d\u1ea1ng, c\u00f3 th\u1ec3 l\u00e0 d\u1ea1ng t\u1ef1 nhi\u00ean, d\u00f9ng \u0111\u01b0\u1eddng \u0111\u1eb7t \u00e2m \u0111\u1ea1o, ho\u1eb7c \u0111\u01b0\u1eddng u\u1ed1ng, ti\u00eam b\u1eafp.<\/p>\n<p>T\u1ed5ng quan h\u1ec7 th\u1ed1ng c\u00f4ng b\u1ed1 n\u0103m 2017 so s\u00e1nh c\u00e1c bi\u1ec7n ph\u00e1p d\u1ef1 ph\u00f2ng sinh non tr\u00ean thai k\u1ef3 \u0111\u01a1n thai nguy c\u01a1 sinh non ho\u1eb7c ti\u1ec1n c\u0103n sinh non k\u1ebft lu\u1eadn progesterone \u2013 \u0111\u1eb7c bi\u1ec7t l\u00e0 d\u1ea1ng t\u1ef1 nhi\u00ean l\u00e0 ph\u01b0\u01a1ng ph\u00e1p c\u00f3 hi\u1ec7u qu\u1ea3 gi\u1ea3m t\u1ef7 l\u1ec7 sinh non v\u00e0 t\u1eed vong s\u01a1 sinh. T\u00ednh t\u1eeb th\u1eddi \u0111i\u1ec3m \u0111\u00f3 \u0111\u1ebfn nay, r\u1ea5t nhi\u1ec1u nghi\u00ean c\u1ee9u v\u1ec1 v\u1ea5n \u0111\u1ec1 n\u00e0y \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1. V\u00ec v\u1eady, m\u1ed9t b\u1ea3n c\u1eadp nh\u1eadt d\u1eef li\u1ec7u t\u1ed5ng quan h\u1ec7 th\u1ed1ng v\u00e0 ph\u00e2n t\u00edch g\u1ed9p \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n nh\u1eb1m cung c\u1ea5p ch\u1ee9ng c\u1ee9 t\u1ed1t nh\u1ea5t cho \u0111\u1ebfn th\u1eddi \u0111i\u1ec3m hi\u1ec7n nay v\u1ec1 d\u1ef1 ph\u00f2ng sinh non.<\/p>\n<p>D\u1eef li\u1ec7u c\u00f4ng b\u1ed1 tr\u00ean BJOG th\u00e1ng 3 n\u0103m 2019 g\u1ed3m 40 nghi\u00ean c\u1ee9u t\u00ednh \u0111\u1ebfn th\u00e1ng 1\/2018 tr\u00ean t\u1ed5ng s\u1ed1 11.311 thai ph\u1ee5 ti\u1ec1n s\u1eed sinh non ho\u1eb7c nguy c\u01a1 sinh non ch\u1ee7 y\u1ebfu d\u1ef1a v\u00e0o chi\u1ec1u d\u00e0i k\u00eanh c\u1ed5 t\u1eed cung ng\u1eafn. Trong \u0111\u00f3 c\u00f3 18 nghi\u00ean c\u1ee9u so s\u00e1nh progesterone v\u1edbi nh\u00f3m ch\u1ee9ng, 11 nghi\u00ean c\u1ee9u so s\u00e1nh kh\u00e2u c\u1ed5 t\u1eed cung v\u1edbi nh\u00f3m ch\u1ee9ng, 4 nghi\u00ean c\u1ee9u so s\u00e1nh v\u00f2ng n\u00e2ng c\u1ed5 t\u1eed cung v\u00e0 nh\u00f3m ch\u1ee9ng, 1 kh\u00e2u c\u1ed5 t\u1eed cung v\u00e0 progesterone, 6 nghi\u00ean c\u1ee9u so s\u00e1nh progesterone \u0111\u1eb7t \u00e2m \u0111\u1ea1o v\u00e0 17 -hydroxyprogesterone caproate.<\/p>\n<h2>K\u1ebft qu\u1ea3 ph\u00e2n t\u00edch cho th\u1ea5y:<\/h2>\n<p>\u1ede nh\u00f3m thai ph\u1ee5 nguy c\u01a1 sinh non, progesterone \u0111\u1eb7t \u00e2m \u0111\u1ea1o c\u00f3 kh\u1ea3 n\u0103ng:<br \/>\ngi\u1ea3m t\u1ef7 l\u1ec7 sinh non &lt; 34 tu\u1ea7n (OR 0,43, 95% CI 0,28 \u2013 0,81)<br \/>\ngi\u1ea3m t\u1ef7 l\u1ec7 sinh &lt; 37 tu\u1ea7n (OR 0,51, 95% CI 0,34 &#8211; 0,74)<br \/>\ngi\u1ea3m t\u1ef7 l\u1ec7 t\u1eed vong s\u01a1 sinh (OR 0,41, 95% CI 0,28 \u2013 0,83)<br \/>\n\u1ede nh\u00f3m b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n c\u0103n sinh non, progesterone \u0111\u1eb7t \u00e2m \u0111\u1ea1o c\u00f3 kh\u1ea3 n\u0103ng:<br \/>\ngi\u1ea3m t\u1ef7 l\u1ec7 sinh non &lt; 34 tu\u1ea7n (OR 0,29, 95% CI 0,12 \u2013 0,68)<br \/>\ngi\u1ea3m t\u1ef7 l\u1ec7 sinh &lt; 37 tu\u1ea7n (OR 0,43, 95% CI 0,23 &#8211; 0,74)<br \/>\nD\u1ea1ng 17 \u03b1-hydroxyprogesterone caproate gi\u1ea3m t\u1ef7 l\u1ec7 sinh &lt; 37 tu\u1ea7n (OR 0,53, 95% CI 0,27 \u2013 0,95) v\u00e0 t\u1eed vong s\u01a1 sinh (OR 0,39, 95% CI 0,16 \u2013 0,95).<br \/>\n\u1ede nh\u00f3m b\u1ec7nh nh\u00e2n c\u00f3 chi\u1ec1u d\u00e0i k\u00eanh c\u1ed5 t\u1eed cung ng\u1eafn (\u2264 25 mm), progesterone \u0111\u1eb7t \u00e2m \u0111\u1ea1o gi\u1ea3m t\u1ef7 l\u1ec7 sinh &lt; 34 tu\u1ea7n (OR 0,45, 95% CI 0,24 \u2013 0,84).<br \/>\nNh\u01b0 v\u1eady, theo k\u1ebft qu\u1ea3 c\u1ee7a t\u1ed5ng quan n\u00e0y, cho \u0111\u1ebfn th\u1eddi \u0111i\u1ec3m hi\u1ec7n t\u1ea1i, progesterone \u0111\u1eb7t \u00e2m \u0111\u1ea1o c\u00f3 hi\u1ec7u qu\u1ea3 d\u1ef1 ph\u00f2ng sinh non tr\u00ean nh\u00f3m b\u1ec7nh nh\u00e2n \u0111\u01a1n thai c\u00f3 nguy c\u01a1 sinh non ho\u1eb7c c\u00f3 ti\u1ec1n s\u1eed sinh non.<\/p>\n<h2>L\u01b0\u1ee3c d\u1ecbch t\u1eeb:<\/h2>\n<p>Jarde A, Lutsiv O, Beyene J, McDonald SD. Vaginal progesterone, oral progesterone, 17-OHPC, cerclage, and pessary for preventing preterm birth in at-risk singleton pregnancies: an updated systematic review and network meta-analysis. BJOG 2019;126:556\u2013567. Link\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30480871\" rel=\"noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30480871<\/a><\/p>\n<p>T\u00e1c gi\u1ea3: B\u00e1c s\u0129 L\u00ea Ti\u1ec3u My \u2013 Nh\u00f3m Nghi\u00ean c\u1ee9u sinh non B\u1ec7nh vi\u1ec7n M\u1ef9 \u0110\u1ee9c<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>M\u1ed7i n\u0103m, tr\u00ean to\u00e0n th\u1ebf gi\u1edbi c\u00f3 kho\u1ea3ng 15 tri\u1ec7u em b\u00e9 ch\u00e0o \u0111\u1eddi tr\u01b0\u1edbc 37 tu\u1ea7n. S\u1ed1 tr\u1ebb t\u1eed vong v\u00ec sinh non v\u1eabn nhi\u1ec1u nh\u1ea5t trong nh\u1eefng nguy\u00ean nh\u00e2n g\u00e2y t\u1eed vong s\u01a1 sinh. V\u00ec v\u1eady, d\u1ef1 ph\u00f2ng sinh non hi\u1ec7n v\u1eabn \u0111ang l\u00e0 \u0111\u1ec1 t\u00e0i \u0111\u01b0\u1ee3c c\u00e1c nh\u00e0 l\u00e2m s\u00e0ng quan t\u00e2m [&#8230;]\n","protected":false},"author":1,"featured_media":5953,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-5952","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/5952","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=5952"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/5952\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/5953"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=5952"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=5952"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=5952"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}