V\u00e0o th\u00e1ng 2 n\u0103m 2019, PRAC \u0111\u00e3 ti\u1ebfn h\u00e0nh \u0111\u00e1nh gi\u00e1 d\u1eef li\u1ec7u li\u00ean quan t\u1edbi vi\u1ec7c s\u1eed d\u1ee5ng PRAC trong th\u1eddi k\u00ec mang thai. Trong tr\u01b0\u1eddng h\u1ee3p n\u00e0y, ANSM th\u00f4ng b\u00e1o r\u1eb1ng modafinil kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb cho ph\u1ee5 n\u1eef mang thai v\u00e0 nh\u1eefng ph\u1ee5 n\u1eef trong \u0111\u1ed9 tu\u1ed5i sinh \u0111\u1ebb m\u00e0 kh\u00f4ng s\u1eed d\u1ee5ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai an to\u00e0n.<\/p>\n
Nh\u1eefng thu\u1ed1c c\u00f3 ch\u1ee9a modafinil (thu\u1ed1c Modiodal v\u00e0 c\u00e1c thu\u1ed1c generic) \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u1edf ng\u01b0\u1eddi l\u1edbn trong \u0111i\u1ec1u tr\u1ecb ch\u1ee9ng bu\u1ed3n ng\u1ee7 ban ng\u00e0y qu\u00e1 m\u1ee9c c\u00f3 li\u00ean quan \u0111\u1ebfn ch\u1ee9ng ng\u1ee7 r\u0169 c\u00f3 ho\u1eb7c kh\u00f4ng c\u00f3 cataplexy (m\u1ea5t tr\u01b0\u01a1ng l\u1ef1c c\u01a1).<\/p>\n
PRAC \u0111\u00e3 ti\u1ebfn h\u00e0nh \u0111\u00e1nh gi\u00e1 nguy c\u01a1 ti\u1ec1m \u1ea9n \u0111\u1ed1i v\u1edbi thai nhi khi s\u1eed d\u1ee5ng modafinil trong th\u1eddi k\u00ec mang thai. Ph\u00e2n t\u00edch n\u00e0y \u0111\u01b0\u1ee3c b\u1eaft \u0111\u1ea7u sau khi nh\u1eadn \u0111\u01b0\u1ee3c k\u1ebft qu\u1ea3 c\u1ee7a m\u1ed9t nghi\u00ean c\u1ee9u quan s\u00e1t t\u1ea1i Hoa K\u1ef3.<\/p>\n
ANSM th\u00f4ng b\u00e1o r\u1eb1ng v\u1edbi ngu\u1ed3n d\u1eef li\u1ec7u c\u00f3 s\u1eb5n t\u1ea1i th\u1eddi \u0111i\u1ec3m n\u00e0y v\u1ec1 nguy c\u01a1 ti\u1ec1m \u1ea9n kh\u00f4ng cho ph\u00e9p ANSM x\u00e1c nh\u1eadn ho\u1eb7c b\u00e1c b\u1ecf nguy c\u01a1 n\u00e0y.<\/p>\n
Trong khi ch\u1edd k\u1ebft lu\u1eadn c\u1ee7a ch\u00e2u \u00c2u, ANSM c\u1ea3nh b\u00e1o r\u1eb1ng:<\/p>\n
Modafinil kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o trong th\u1eddi k\u00ec mang thai v\u00e0 nh\u1eefng ph\u1ee5 n\u1eef trong \u0111\u1ed9 tu\u1ed5i mang thai m\u00e0 kh\u00f4ng s\u1eed d\u1ee5ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai an to\u00e0n n\u00e0o.<\/p>\n
Hi\u1ec7u qu\u1ea3 c\u1ee7a thu\u1ed1c tr\u00e1nh thai \u0111\u01b0\u1eddng u\u1ed1ng c\u00f3 th\u1ec3 gi\u1ea3m khi s\u1eed d\u1ee5ng c\u00f9ng v\u1edbi modafinil v\u00e0 c\u00f3 th\u1ec3 chuy\u1ec3n sang s\u1eed d\u1ee5ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai thay th\u1ebf ho\u1eb7c k\u1ebft h\u1ee3p \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n \u0111ang \u0111i\u1ec1u tr\u1ecb.<\/p>\n
Bi\u1ec7n ph\u00e1p tr\u00e1nh thai thay th\u1ebf ho\u1eb7c b\u1ed5 sung n\u00ean ti\u1ebfp t\u1ee5c s\u1eed d\u1ee5ng trong v\u00f2ng 2 th\u00e1ng khi ng\u1eebng s\u1eed d\u1ee5ng modafinil.<\/p>\n
C\u00e1c lo\u1ea1i thu\u1ed1c ch\u1ee9a modafinil ph\u1ea3i tu\u00e2n th\u1ee7 theo \u0111\u01a1n c\u1ee7a c\u00e1c chuy\u00ean gia th\u1ea7n kinh, c\u00e1c trung t\u00e2m th\u1ea7n kinh v\u00e0 gi\u00e1c ng\u1ee7 t\u1ea1i Ph\u00e1p.<\/p>\n
Ng\u01b0\u1eddi t\u1ed5ng h\u1ee3p: V\u0169 \u0110\u1ee9c Ho\u00e0n – Nguy\u1ec5n Ph\u01b0\u01a1ng Th\u00fay<\/p>\n
<\/p>\n
<\/p>\n
<\/p>\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
V\u00e0o th\u00e1ng 2 n\u0103m 2019, PRAC \u0111\u00e3 ti\u1ebfn h\u00e0nh \u0111\u00e1nh gi\u00e1 d\u1eef li\u1ec7u li\u00ean quan t\u1edbi vi\u1ec7c s\u1eed d\u1ee5ng PRAC trong th\u1eddi k\u00ec mang thai. Trong tr\u01b0\u1eddng h\u1ee3p n\u00e0y, ANSM th\u00f4ng b\u00e1o r\u1eb1ng modafinil kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb cho ph\u1ee5 n\u1eef mang thai v\u00e0 nh\u1eefng ph\u1ee5 n\u1eef trong \u0111\u1ed9 tu\u1ed5i sinh \u0111\u1ebb m\u00e0 kh\u00f4ng s\u1eed […]\n","protected":false},"author":1,"featured_media":5813,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-5812","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/5812","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=5812"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/5812\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/5813"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=5812"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=5812"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=5812"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}