{"id":55763,"date":"2023-11-08T10:27:32","date_gmt":"2023-11-08T03:27:32","guid":{"rendered":"https:\/\/vnras.com\/drug\/?p=55763"},"modified":"2024-05-06T11:05:39","modified_gmt":"2024-05-06T04:05:39","slug":"thuoc-ha-mo-mau-va-nhung-luu-y-khi-su-dung","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/thuoc-ha-mo-mau-va-nhung-luu-y-khi-su-dung\/","title":{"rendered":"Thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u v\u00e0 nh\u1eefng l\u01b0u \u00fd khi s\u1eed d\u1ee5ng"},"content":{"rendered":"

T\u0103ng lipid m\u00e1u l\u00e0 m\u1ed9t trong nh\u1eefng y\u1ebfu t\u1ed1 nguy c\u01a1 ph\u00e1t tri\u1ec3n b\u1ec7nh tim m\u1ea1ch. Thu\u1ed1c h\u1ea1 lipid m\u00e1u l\u00e0 g\u00ec? C\u00f3 nh\u1eefng l\u01b0u \u00fd g\u00ec khi s\u1eed d\u1ee5ng c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y? B\u00e0i vi\u1ebft d\u01b0\u1edbi \u0111\u00e2y, D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng s\u1ebd cung c\u1ea5p cho b\u1ea1n \u0111\u1ecdc nh\u1eefng th\u00f4ng tin c\u1ea7n thi\u1ebft v\u1ec1 thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u<\/b><\/p>\n

T\u0103ng lipid m\u00e1u l\u00e0 g\u00ec?<\/span><\/h2>\n
T\u0103ng lipid m\u00e1u \u0111\u01b0\u1ee3c coi l\u00e0 m\u1ed9t trong nh\u1eefng y\u1ebfu t\u1ed1 nguy c\u01a1 ch\u00ednh g\u00e2y ra c\u00e1c b\u1ec7nh tim m\u1ea1ch (CVD). CVD chi\u1ebfm 1\/3 t\u1ed5ng s\u1ed1 ca t\u1eed vong tr\u00ean to\u00e0n th\u1ebf gi\u1edbi, c\u00e1c nh\u00e0 khoa h\u1ecdc tin r\u1eb1ng CVD (c\u00e1c b\u1ec7nh tim m\u1ea1ch) s\u1ebd tr\u1edf th\u00e0nh nguy\u00ean nh\u00e2n ch\u00ednh g\u00e2y t\u1eed vong v\u00e0 t\u00e0n t\u1eadt tr\u00ean to\u00e0n th\u1ebf gi\u1edbi v\u00e0o n\u0103m 2020.<\/span><\/p>\n
T\u0103ng lipid m\u00e1u l\u00e0 s\u1ef1 gia t\u0103ng m\u1ed9t ho\u1eb7c nhi\u1ec1u lipid trong huy\u1ebft t\u01b0\u01a1ng, bao g\u1ed3m triglycerid, cholesterol, este cholesterol v\u00e0 phospholipid v\u00e0 ho\u1eb7c lipoprotein huy\u1ebft t\u01b0\u01a1ng bao g\u1ed3m lipoprotein m\u1eadt \u0111\u1ed9 r\u1ea5t th\u1ea5p v\u00e0 lipoprotein m\u1eadt \u0111\u1ed9 th\u1ea5p, v\u00e0 gi\u1ea3m m\u1ee9c lipoprotein m\u1eadt \u0111\u1ed9 cao.<\/span><\/p>\n
T\u0103ng cholesterol m\u00e1u v\u00e0 t\u0103ng triglycerid m\u00e1u l\u00e0 nguy\u00ean nh\u00e2n ch\u00ednh g\u00e2y x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch, li\u00ean quan ch\u1eb7t ch\u1ebd \u0111\u1ebfn b\u1ec7nh tim thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9 (IHD). C\u00f3 m\u1ed1i li\u00ean h\u1ec7 ch\u1eb7t ch\u1ebd gi\u1eefa b\u1ec7nh tim thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9 v\u00e0 t\u1ef7 l\u1ec7 t\u1eed vong cao. H\u01a1n n\u1eefa, n\u1ed3ng \u0111\u1ed9 cholesterol trong huy\u1ebft t\u01b0\u01a1ng t\u0103ng cao g\u00e2y ra h\u01a1n 4 tri\u1ec7u ca t\u1eed vong trong m\u1ed9t n\u0103m.<\/span><\/p>\n
X\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch l\u00e0 m\u1ed9t qu\u00e1 tr\u00ecnh x\u01a1 c\u1ee9ng \u0111\u1ed9ng m\u1ea1ch do s\u1ef1 l\u1eafng \u0111\u1ecdng cholesterol trong th\u00e0nh \u0111\u1ed9ng m\u1ea1ch g\u00e2y h\u1eb9p \u0111\u1ed9ng m\u1ea1ch. X\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch v\u00e0 c\u00e1c r\u1ed1i lo\u1ea1n li\u00ean quan \u0111\u1ebfn x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch nh\u01b0 b\u1ec7nh m\u1ea1ch v\u00e0nh, m\u1ea1ch m\u00e1u n\u00e3o v\u00e0 m\u1ea1ch m\u00e1u ngo\u1ea1i bi\u00ean \u0111\u01b0\u1ee3c \u0111\u1ea9y nhanh do s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a t\u0103ng lipid m\u00e1u.<\/span><\/p>\n
T\u0103ng lipid m\u00e1u li\u00ean quan \u0111\u1ebfn s\u1ef1 gia t\u0103ng c\u0103ng th\u1eb3ng oxy h\u00f3a g\u00e2y ra s\u1ef1 s\u1ea3n sinh \u0111\u00e1ng k\u1ec3 c\u00e1c g\u1ed1c t\u1ef1 do oxy, c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn s\u1ef1 bi\u1ebfn \u0111\u1ed5i oxy h\u00f3a trong c\u00e1c lipoprotein m\u1eadt \u0111\u1ed9 th\u1ea5p, c\u00f3 ch\u1ee9c n\u0103ng quan tr\u1ecdng trong vi\u1ec7c kh\u1edfi \u0111\u1ea7u v\u00e0 ti\u1ebfn tri\u1ec3n c\u1ee7a ch\u1ee9ng x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch v\u00e0 c\u00e1c b\u1ec7nh tim m\u1ea1ch li\u00ean quan.<\/span><\/p>\n
Nguy\u00ean nh\u00e2n<\/span><\/h2>\n
T\u0103ng lipid m\u00e1u \u0111\u01b0\u1ee3c chia th\u00e0nh hai lo\u1ea1i ch\u00ednh: t\u0103ng lipid m\u00e1u nguy\u00ean ph\u00e1t (gia \u0111\u00ecnh) ho\u1eb7c th\u1ee9 ph\u00e1t (m\u1eafc ph\u1ea3i). T\u0103ng lipid m\u00e1u nguy\u00ean ph\u00e1t xu\u1ea5t ph\u00e1t t\u1eeb r\u1ea5t nhi\u1ec1u r\u1ed1i lo\u1ea1n di truy\u1ec1n m\u00e0 b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 di truy\u1ec1n qua khi sinh, trong khi t\u0103ng lipid m\u00e1u th\u1ee9 ph\u00e1t th\u01b0\u1eddng b\u1eaft ngu\u1ed3n t\u1eeb m\u1ed9t nguy\u00ean nh\u00e2n c\u01a1 b\u1ea3n thay th\u1ebf, ch\u1eb3ng h\u1ea1n nh\u01b0 ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng kh\u00f4ng l\u00e0nh m\u1ea1nh, thu\u1ed1c (amiodarone, glucocorticoid), suy gi\u00e1p, ti\u1ec3u \u0111\u01b0\u1eddng kh\u00f4ng ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c v\u00e0\/ho\u1eb7c ch\u1ebf \u0111\u1ed9 sinh ho\u1ea1t k\u00e9m.<\/span><\/p>\n
Nguy\u00ean t\u1eafc \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n lipoprotein m\u00e1u<\/span><\/h2>\n
$\"Nguy\u00ean$ <\/a>
Nguy\u00ean t\u1eafc \u0111i\u1ec1u tr\u1ecb<\/figcaption><\/figure>\n
\u0110\u1ec3 gi\u1ea3m t\u1ed1i \u0111a nguy c\u01a1 xu\u1ea5t g\u00e2y b\u1ec7nh tim m\u1ea1ch, ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n h\u1ea1 LDL v\u00e0 t\u0103ng HDL trong m\u00e1u.<\/span><\/p>\n
Nguy\u00ean t\u1eafc \u0111i\u1ec1u tr\u1ecb:<\/span><\/p>\n
\n
\u0110i\u1ec1u ch\u1ec9nh ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng.<\/span><\/li>\n
Duy tr\u00ec tr\u1ecdng l\u01b0\u1ee3ng c\u01a1 th\u1ec3 \u1edf m\u1ee9c b\u00ecnh th\u01b0\u1eddng.<\/span><\/li>\n
\u0110i\u1ec1u tr\u1ecb nguy\u00ean nh\u00e2n g\u00e2y t\u0103ng lipoprotein m\u00e1u bao g\u1ed3m: h\u00fat thu\u1ed1c l\u00e1, s\u1eed d\u1ee5ng thu\u1ed1c corticoid, s\u1eed d\u1ee5ng r\u01b0\u1ee3u bia, thu\u1ed1c tr\u00e1nh thai,…<\/span><\/li>\n
T\u0103ng v\u1eadn \u0111\u1ed9ng th\u1ec3 l\u1ef1c.<\/span><\/li>\n
S\u1eed d\u1ee5ng<\/span> thu\u1ed1c gi\u1ea3m m\u1ee1 m\u00e1u<\/b> khi c\u1ea7n thi\u1ebft. C\u00f3 th\u1ec3 c\u1ea7n ph\u1ea3i ph\u1ed1i h\u1ee3p 2-3 thu\u1ed1c c\u00f3 c\u01a1 ch\u1ebf kh\u00e1c nhau \u0111\u1ec3 ki\u1ec3m so\u00e1t n\u1ed3ng \u0111\u1ed9 lipoprotein trong m\u00e1u: Cholestyramin ph\u1ed1i h\u1ee3p v\u1edbi d\u1eabn xu\u1ea5t statin, Cholestyramin ph\u1ed1i h\u1ee3p v\u1edbi acid nicotinic, Cholestyramin ph\u1ed1i h\u1ee3p v\u1edbi d\u1eabn xu\u1ea5t statin v\u00e0 acid nicotinic.<\/span><\/li>\n
C\u1ea7n l\u01b0u \u00fd r\u1eb1ng, c\u00e1c d\u1eabn xu\u1ea5t statin th\u01b0\u1eddng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho nh\u1eefng b\u1ec7nh nh\u00e2n t\u0103ng cholesterol c\u00f2n d\u1eabn xu\u1ea5t acid fibric \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh nh\u00e2n t\u0103ng triglyceride. C\u00f3 th\u1ec3 s\u1eed d\u1ee5ng ri\u00eang r\u1ebd ho\u1eb7c ph\u1ed1i h\u1ee3p 2 lo\u1ea1i thu\u1ed1c n\u00e0y trong tr\u01b0\u1eddng h\u1ee3p t\u0103ng lipoprotein h\u1ed7n h\u1ee3p nh\u01b0ng c\u1ea7n th\u1eadn tr\u1ecdng.<\/span><\/li>\n<\/ul>\n
Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, b\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i l\u01b0\u1ee3ng lipoprotein trong m\u00e1u v\u00e0 t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u00f3 th\u1ec3 x\u1ea3y ra.<\/span><\/p>\n
Ph\u00e2n lo\u1ea1i c\u00e1c thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u<\/span><\/h2>\n
D\u1ef1a v\u00e0o c\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng, c\u00e1c thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u \u0111\u01b0\u1ee3c chia th\u00e0nh 2 nh\u00f3m:<\/span><\/p>\n
\n
Thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u gi\u00fap l\u00e0m gi\u1ea3m h\u1ea5p thu v\u00e0 t\u0103ng th\u1ea3i tr\u1eeb lipid.<\/span><\/li>\n
Thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u gi\u00fap l\u00e0m gi\u1ea3m t\u1ed5ng h\u1ee3p lipid.<\/span><\/li>\n<\/ul>\n
Thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u l\u00e0m gi\u1ea3m h\u1ea5p thu v\u00e0 t\u0103ng th\u1ea3i tr\u1eeb lipid<\/span><\/h2>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u l\u00e0m gi\u1ea3m h\u1ea5p thu v\u00e0 t\u0103ng th\u1ea3i tr\u1eeb lipid<\/figcaption><\/figure>\n
C\u01a1 ch\u1ebf: H\u1ea5p th\u1ee5 m\u1ea1nh \u0111\u1ed3ng th\u1eddi t\u1ea1o ph\u1ee9c v\u1edbi acid m\u1eadt t\u1eeb \u0111\u00f3 l\u00e0m gi\u1ea3m qu\u00e1 tr\u00ecnh nh\u0169 h\u00f3a lipid \u1edf ru\u1ed9t d\u1eabn \u0111\u1ebfn l\u00e0m gi\u1ea3m qu\u00e1 tr\u00ecnh h\u1ea5p thu v\u00e0 t\u0103ng \u0111\u00e0o th\u1ea3i lipid qua ph\u00e2n. B\u00ean c\u1ea1nh \u0111\u00f3, c\u00e1c thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u nh\u00f3m n\u00e0y c\u00f2n c\u00f3 t\u00e1c d\u1ee5ng gi\u00e1n ti\u1ebfp l\u00e0m t\u0103ng chuy\u1ec3n h\u00f3a cholesterol th\u00e0nh acid m\u1eadt nh\u1edd s\u1ef1 tho\u00e1t \u1ee9c ch\u1ebf hydroxylase \u1edf microsom gan \u0111\u1ed3ng th\u1eddi l\u00e0m t\u0103ng s\u1ed1 l\u01b0\u1ee3ng, t\u0103ng ho\u1ea1t t\u00ednh c\u1ee7a LDL-receptor \u1edf m\u00e0ng t\u1ebf b\u00e0o.<\/span><\/p>\n
Cholestyramin<\/span><\/h3>\n
Cholestyramine \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 l\u00e0m gi\u1ea3m l\u01b0\u1ee3ng cholesterol cao trong m\u00e1u, \u0111\u1eb7c bi\u1ec7t l\u00e0 lipoprotein m\u1eadt \u0111\u1ed9 th\u1ea5p (LDL).<\/span><\/p>\n
\u0110\u1eb7c \u0111i\u1ec3m c\u1ee7a Cholestyramine:<\/span><\/p>\n
\n
L\u00e0 ch\u1ea5t nh\u1ef1a trao \u0111\u1ed5i ion.<\/span><\/li>\n
C\u00f3 t\u00ednh baz\u01a1 m\u1ea1nh.<\/span><\/li>\n
Kh\u00f4ng tan trong n\u01b0\u1edbc.<\/span><\/li>\n
Khi s\u1eed d\u1ee5ng theo \u0111\u01b0\u1eddng u\u1ed1ng g\u1ea7n nh\u01b0 kh\u00f4ng h\u1ea5p thu qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/span><\/li>\n
Kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1c enzym \u1edf \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/span><\/li>\n<\/ul>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng:<\/span><\/p>\n
\n
Trao \u0111\u1ed5i ion ion clo v\u1edbi acid m\u1eadt t\u1ea1o ph\u1ee9c h\u1ee3p nh\u1ef1a g\u1eafn acid m\u1eadt l\u00e0m t\u0103ng \u0111\u00e0o th\u1ea3i qua ph\u00e2n.<\/span><\/li>\n
\u1ee8c ch\u1ebf chu k\u1ef3 gan ru\u1ed9t c\u1ee7a acid m\u1eadt t\u1eeb \u0111\u00f3 l\u00e0m t\u0103ng t\u1ed5ng h\u1ee3p acid m\u1eadt t\u1eeb cholesterol.<\/span><\/li>\n
Gi\u1ea3m acid m\u1eadt d\u1eabn \u0111\u1ebfn gi\u1ea3m s\u1ef1 h\u1ea5p thu sterol.<\/span><\/li>\n<\/ul>\n
Sau khi u\u1ed1ng, thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u Cholestyramine c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m LDL trong m\u00e1u sau 4-7 ng\u00e0y, t\u00e1c d\u1ee5ng t\u1ed1i \u0111a trong v\u00f2ng 2 tu\u1ea7n.<\/span><\/p>\n
\u1ede h\u1ea7u h\u1ebft b\u1ec7nh nh\u00e2n, Cholestyramine c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m t\u0103ng triglycerid t\u1eeb 5 \u0111\u1ebfn 20% so v\u1edbi tr\u01b0\u1edbc khi \u0111i\u1ec1u tr\u1ecb. Tuy nhi\u00ean, ch\u1ec9 s\u1ed1 n\u00e0y s\u1ebd d\u1ea7n tr\u1edf v\u1ec1 gi\u00e1 tr\u1ecb ban \u0111\u1ea7u trong 4 tu\u1ea7n.<\/span><\/p>\n
Cholestyramine c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m t\u0103ng HDL – cholesterol kho\u1ea3ng 5%, gi\u1ea3m LDL-cholesterol kho\u1ea3ng 10-30% (c\u00f2n ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec1u l\u01b0\u1ee3ng).<\/span><\/p>\n
Do c\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng l\u00e0 t\u1ea1o ph\u1ee9c v\u1edbi acid m\u1eadt n\u00ean khi s\u1eed d\u1ee5ng Cholestyramine, m\u1ed9t s\u1ed1 ng\u01b0\u1eddi b\u1ec7nh c\u00f3 th\u1ec3 g\u1eb7p t\u00ecnh tr\u1ea1ng bu\u1ed3n n\u00f4n, kh\u00f3 ch\u1ecbu v\u00f9ng b\u1ee5ng, h\u1ea1 prothrombin.<\/span><\/p>\n
Cholestyramine c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m h\u1ea5p thu m\u1ed9t s\u1ed1 thu\u1ed1c d\u00f9ng \u0111\u1ed3ng th\u1eddi bao g\u1ed3m:<\/span><\/p>\n
\n
Digoxin.<\/span><\/li>\n
Phenylbutazon.<\/span><\/li>\n
Phenobarbital.<\/span><\/li>\n
Clorothiazid.<\/span><\/li>\n
Thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng d\u1eabn xu\u1ea5t coumarin.<\/span><\/li>\n
Thyroxin.<\/span><\/li>\n<\/ul>\n
Colestipol<\/span><\/h3>\n
\u0110\u1eb7c \u0111i\u1ec3m:<\/span><\/p>\n
\n
L\u00e0 polyme c\u1ee7a dethylpentamin v\u00e0 epiclohydrin.<\/span><\/li>\n
Tan trong n\u01b0\u1edbc.<\/span><\/li>\n
H\u00fat \u1ea9m r\u1ea5t m\u1ea1nh.<\/span><\/li>\n<\/ul>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng, t\u00e1c d\u1ee5ng, t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n t\u01b0\u01a1ng t\u1ef1 nh\u01b0 Cholestyramin.<\/span><\/p>\n
Neomycin<\/span><\/h3>\n
L\u00e0 kh\u00e1ng sinh nh\u00f3m aminoglycosid c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m h\u1ea1 lipoprotein m\u00e1u (\u0111\u1eb7c bi\u1ec7t l\u00e0 LDL-cholesterol).<\/span><\/p>\n
T\u00e1c d\u1ee5ng h\u1ea1 m\u1ee1 m\u00e1u kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o t\u00e1c d\u1ee5ng kh\u00e1ng khu\u1ea9n.<\/span><\/p>\n
Ezetimibe<\/span><\/h3>\n
L\u00e0 thu\u1ed1c \u1ee9c ch\u1ebf h\u1ea5p thu cholesterol \u1edf ru\u1ed9t.<\/span><\/p>\n
Th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u01a1n \u0111\u1ed9c ho\u1eb7c ph\u1ed1i h\u1ee3p v\u1edbi statin cho nh\u1eefng b\u1ec7nh nh\u00e2n t\u0103ng cholesterol m\u00e1u do ch\u1ebf \u0111\u1ed9 \u0103n ho\u1eb7c di truy\u1ec1n. Li\u1ec1u d\u00f9ng trong tr\u01b0\u1eddng h\u1ee3p n\u00e0y l\u00e0 10mg\/ng\u00e0y.<\/span><\/p>\n
Thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u l\u00e0m gi\u1ea3m t\u1ed5ng h\u1ee3p lipid<\/span><\/h2>\n
C\u00e1c thu\u1ed1c nh\u00f3m n\u00e0y bao g\u1ed3m:<\/span><\/p>\n
\n
D\u1eabn xu\u1ea5t c\u1ee7a acid fibric: Bezafibrate, gemfibrozil, fenofibrate, ciprofibrate.<\/span><\/li>\n
D\u1eabn xu\u1ea5t statin: Pravastatin, Rosuvastatine, Simvastatin, Lovastatin.<\/span><\/li>\n
Acid Nicotinic.<\/span><\/li>\n
Probucol.<\/span><\/li>\n
Thu\u1ed1c \u1ee9c ch\u1ebf PCSK9.<\/span><\/li>\n<\/ul>\n
C\u00e1c d\u1eabn xu\u1ea5t c\u1ee7a acid fibric c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m t\u0103ng ho\u1ea1t t\u00ednh c\u1ee7a lipoprotein lipase.<\/span><\/p>\n
C\u00e1c d\u1eabn xu\u1ea5t c\u1ee7a statin c\u00f3 c\u1ea5u tr\u00fac t\u01b0\u01a1ng t\u1ef1 v\u1edbi HMG-CoA n\u00ean c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf c\u1ea1nh tranh v\u1edbi HMG-CoA-reductase t\u1eeb \u0111\u00f3 l\u00e0m gi\u1ea3m t\u1ed5ng h\u1ee3p cholesterol, \u0111\u1ed3ng th\u1eddi thu\u1ed1c c\u0169ng c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m t\u0103ng sinh LDL-receptor \u1edf m\u00e0ng t\u1ebf b\u00e0o.<\/span><\/p>\n
Acid nicotinic l\u00e0 m\u1ed9t vitamin \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh Pellagra. Tuy nhi\u00ean, acid nicotinic c\u0169ng c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m h\u1ea1 lipoprotein m\u00e1u. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c l\u00e0 do l\u00e0m t\u0103ng sinh LDL-receptor \u0111\u1ed3ng th\u1eddi \u1ee9c ch\u1ebf s\u1ef1 t\u00edch t\u1ee5 c\u1ee7a AMP trong m\u1ee1, t\u0103ng ho\u1ea1t t\u00ednh c\u1ee7a triglyceride lipase.<\/span><\/p>\n
Probucol c\u00f3 c\u1ea5u tr\u00fac kh\u00e1c v\u1edbi c\u00e1c nh\u00f3m thu\u1ed1c kh\u00e1c. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a Probucol \u0111\u1ebfn nay v\u1eabn ch\u01b0a th\u1ef1c s\u1ef1 \u0111\u01b0\u1ee3c hi\u1ec3u r\u00f5. M\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u cho th\u1ea5y, Probucol l\u00e0m t\u0103ng chuy\u1ec3n h\u00f3a LDL-cholesterol tuy nhi\u00ean kh\u00f4ng th\u00f4ng qua LDL-receptor. C\u00f3 gi\u1ea3 thuy\u1ebft cho r\u1eb1ng, Probucol c\u00f3 t\u00e1c d\u1ee5ng ng\u0103n c\u1ea3n oxy h\u00f3a c\u1ee7a acid b\u00e9o \u0111\u1ed3ng th\u1eddi l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng ti\u1ebfp nh\u1eadn LDL c\u1ee7a c\u00e1c t\u1ebf b\u00e0o n\u1ed9i m\u00f4.<\/span><\/p>\n
Acid Nicotinic (Vitamin PP, Vitamin B3, Niacin)<\/span><\/h3>\n
$\"Acid$ <\/a>
Acid Nicotinic<\/figcaption><\/figure>\n
\u0110\u1eb7c \u0111i\u1ec3m:<\/span><\/p>\n
\n
Tan trong n\u01b0\u1edbc.<\/span><\/li>\n
T\u00ecm th\u1ea5y nhi\u1ec1u trong c\u00e1c th\u1ef1c ph\u1ea9m bao g\u1ed3m: Th\u1ecbt, c\u00e1, gan, rau, qu\u1ea3, ng\u0169 c\u1ed1c. Ngo\u00e0i ra, c\u00e1c vi khu\u1ea9n trong \u0111\u01b0\u1eddng ru\u1ed9t c\u00f3 th\u1ec3 t\u1ed5ng h\u1ee3p \u0111\u01b0\u1ee3c m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf vitamin PP.<\/span><\/li>\n<\/ul>\n
Acid Nicotinic c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m lipoprotein m\u00e1u r\u00f5 r\u1ec7t. M\u1ee9c \u0111\u1ed9 gi\u1ea3m triglyceride l\u00e0 20 \u0111\u1ebfn 80% sau 1-4 ng\u00e0y s\u1eed d\u1ee5ng thu\u1ed1c. Acid Nicotinic c\u00f3 t\u00e1c d\u1ee5ng t\u1ed1i \u0111a sau 3 \u0111\u1ebfn 5 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb.<\/span><\/p>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng:<\/span><\/p>\n
\n
L\u00e0m gi\u1ea3m s\u1ea3n xu\u1ea5t v\u00e0 t\u0103ng th\u1ea3i VLDL.<\/span><\/li>\n
\u1ee8c ch\u1ebf ph\u00e2n h\u1ee7y lipid.<\/span><\/li>\n
Gi\u1ea3m cung c\u1ea5p acid b\u00e9o cho gan.<\/span><\/li>\n
Gi\u1ea3m t\u1ed5ng h\u1ee3p triglyceride.<\/span><\/li>\n
Gi\u1ea3m v\u1eadn chuy\u1ec3n triglyceride, VLDL.<\/span><\/li>\n
Gi\u1ea3m s\u1ea3n xu\u1ea5t LDL.<\/span><\/li>\n
T\u0103ng HDL nh\u01b0ng ch\u01b0a r\u00f5 c\u01a1 ch\u1ebf.<\/span><\/li>\n<\/ul>\n
L\u01b0u \u00fd:<\/span><\/p>\n
\n
\u0110\u1ec3 l\u00e0m gi\u1ea3m nguy c\u01a1 xu\u1ea5t hi\u1ec7n t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n, ng\u01b0\u1eddi b\u1ec7nh n\u00ean u\u1ed1ng thu\u1ed1c v\u00e0o b\u1eefa \u0103n.<\/span><\/li>\n
Li\u1ec1u u\u1ed1ng t\u0103ng d\u1ea7n.<\/span><\/li>\n<\/ul>\n
Acid Nicotinic \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh nh\u00e2n t\u0103ng lipoprotein m\u00e1u typ II, III, IV v\u00e0 V.<\/span><\/p>\n
C\u00f3 th\u1ec3 c\u1ea7n thi\u1ebft ph\u1ed1i h\u1ee3p v\u1edbi cholestyramine v\u00e0 colestipol \u0111\u1ec3 gi\u1ea3m t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n.<\/span><\/p>\n
D\u1eabn xu\u1ea5t c\u1ee7a acid fibric<\/span><\/h3>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u nh\u00f3m fibrat<\/figcaption><\/figure>\n
\u0110\u1eb7c \u0111i\u1ec3m:<\/span><\/p>\n
\n
H\u1ea5p thu t\u1ed1t qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/span><\/li>\n
G\u1eafn m\u1ea1nh v\u1edbi protein huy\u1ebft.<\/span><\/li>\n<\/ul>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng l\u00e0 l\u00e0m t\u0103ng ho\u1ea1t t\u00ednh lipoprotein lipase \u1edf t\u1ebf b\u00e0o c\u01a1 t\u1eeb \u0111\u00f3 l\u00e0m t\u0103ng th\u1ee7y ph\u00e2n triglyceride v\u00e0 t\u0103ng tho\u00e1i h\u00f3a VLDL.<\/span><\/p>\n
C\u00e1c d\u1eabn xu\u1ea5t c\u1ee7a acid fibric c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m t\u0103ng HDL nh\u01b0ng c\u01a1 ch\u1ebf ch\u01b0a r\u00f5 r\u00e0ng.<\/span><\/p>\n
Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng v\u1edbi b\u1ec7nh nh\u00e2n suy gi\u1ea3m ch\u1ee9c n\u0103ng gan, suy th\u1eadn, b\u1ec7nh nh\u00e2n c\u00f3 s\u1ecfi \u1edf m\u1eadt, ph\u1ee5 n\u1eef c\u00f3 thai, ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa, tr\u1ebb em < 10 tu\u1ed5i.<\/span><\/p>\n\n\n\n\n\n\n\n
T\u00ean thu\u1ed1c<\/span><\/td>\n Bi\u1ec7t d\u01b0\u1ee3c<\/span><\/td>\n Thu\u1ed1c th\u01b0\u01a1ng m\u1ea1i<\/span><\/td>\n<\/tr>\n
Fenofibrate<\/span><\/td>\n Thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u Lipanthyl.<\/b><\/p>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n
Ngo\u00e0i ra, c\u00f2n c\u00f3 m\u1ed9t s\u1ed1 bi\u1ec7t d\u01b0\u1ee3c kh\u00e1c nh\u01b0 Antara , Fenoglide, Lipofen, TriCor, Triglide.<\/span><\/td>\n
Colestrim Supra do Mega Lifesciences Public Company Ltd. s\u1ea3n xu\u1ea5t.<\/span><\/p>\n
Fenostad 160 do C\u00f4ng ty TNHH Li\u00ean doanh Stella Pharm s\u1ea3n xu\u1ea5t c\u00f3 gi\u00e1 105.000 \u0111\u1ed3ng\/h\u1ed9p 30 vi\u00ean.<\/span><\/p>\n
Fenofibrat Savi 200M do C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Savipharm s\u1ea3n xu\u1ea5t c\u00f3 gi\u00e1 240.000 \u0111\u1ed3ng\/h\u1ed9p 30 vi\u00ean.<\/span><\/td>\n<\/tr>\n
Bezafibrat<\/span><\/td>\n Bezalip<\/span><\/td>\n Zafular do Medochemie Ltd. s\u1ea3n xu\u1ea5t c\u00f3 gi\u00e1 225.000 \u0111\u1ed3ng\/h\u1ed9p 50 vi\u00ean.<\/span><\/p>\n
Agibeza 200 ch\u1ee9a Bezafibrat h\u00e0m l\u01b0\u1ee3ng 200mg do C\u00f4ng ty c\u1ed5 ph\u1ea7n Agimexpharm s\u1ea3n xu\u1ea5t.<\/span><\/td>\n<\/tr>\n
Gemfibrozil<\/span><\/td>\n Lopid<\/span><\/td>\n SaVi Gemfibrozil 600 ch\u1ee9a Gemfibrozil h\u00e0m l\u01b0\u1ee3ng 600mg do C\u00f4ng ty\u00a0<\/span><\/p>\n
SaVipharm s\u1ea3n xu\u1ea5t.<\/span><\/p>\n
Gemfibstad 300 ch\u1ee9a Gemfibrozil h\u00e0m l\u01b0\u1ee3ng 300mg do C\u00f4ng ty TNHH Li\u00ean doanh Stella Pharm s\u1ea3n xu\u1ea5t c\u00f3 gi\u00e1 155.000 \u0111\u1ed3ng\/h\u1ed9p 60 vi\u00ean.<\/span><\/td>\n<\/tr>\n
Ciprofibrate<\/span><\/td>\n Lipanor<\/span><\/td>\n Glenlipid 100mg do C\u00f4ng ty Glenmark Pharmaceuticals LTD s\u1ea3n xu\u1ea5t.<\/span><\/p>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n
Modalim 100mg do Sanofi-Synthelabo s\u1ea3n xu\u1ea5t c\u00f3 gi\u00e1 240.000 \u0111\u1ed3ng\/h\u1ed9p 28 vi\u00ean.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
D\u1eabn xu\u1ea5t statin<\/span><\/h3>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u nh\u00f3m statin<\/figcaption><\/figure>\n\n\n\n\n\n\n\n\n\n
T\u00ean g\u1ed1c<\/span><\/td>\n Bi\u1ec7t d\u01b0\u1ee3c<\/span><\/td>\n Li\u1ec1u l\u01b0\u1ee3ng<\/span><\/td>\n Thu\u1ed1c th\u01b0\u01a1ng m\u1ea1i<\/span><\/td>\n<\/tr>\n
Atorvastatin<\/span><\/td>\n Lipitor v\u1edbi c\u00e1c h\u00e0m l\u01b0\u1ee3ng 10mg, 20mg, 40mg<\/span><\/td>\n Ban \u0111\u1ea7u, 10mg m\u1ed7i ng\u00e0y. N\u00ean d\u00f9ng <\/span>thu\u1ed1c gi\u1ea3m m\u1ee1 m\u00e1u atorvastatin<\/b> tr\u01b0\u1edbc khi \u0111i ng\u1ee7, nh\u01b0ng c\u00f3 th\u1ec3 d\u00f9ng li\u1ec1u b\u1ea5t c\u1ee9 l\u00fac n\u00e0o, kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o b\u1eefa \u0103n.<\/span><\/p>\n
T\u0103ng li\u1ec1u n\u1ebfu \u0111\u00e1p \u1ee9ng kh\u00f4ng \u0111\u1ee7 sau 4 tu\u1ea7n.<\/span><\/p>\n
Li\u1ec1u t\u1ed1i \u0111a: 80 mg m\u1ed7i ng\u00e0y<\/span><\/td>\n
Lipitor 10mg do Pfizer Ireland Pharmaceuticals s\u1ea3n xu\u1ea5t, thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 475.000VN\u0110\/h\u1ed9p. Ngo\u00e0i ra, c\u00f2n c\u00f3 <\/span>Lipitor 20mg<\/span>.<\/p>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n
Lipitor 40mg<\/span>.<\/span><\/p>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n
<\/td>\n<\/tr>\n
Fluvastatin<\/span><\/td>\n Lescol<\/span><\/td>\n Ban \u0111\u1ea7u, 20 mg m\u1ed7i ng\u00e0y tr\u01b0\u1edbc khi \u0111i ng\u1ee7, kh\u00f4ng li\u00ean quan \u0111\u1ebfn b\u1eefa \u0103n.<\/span><\/p>\n
T\u0103ng l\u00ean 40 mg m\u1ed7i ng\u00e0y n\u1ebfu \u0111\u00e1p \u1ee9ng kh\u00f4ng \u0111\u1ee7 sau 4 tu\u1ea7n.<\/span><\/p>\n
Li\u1ec1u t\u1ed1i \u0111a: 80 mg m\u1ed7i ng\u00e0y, chia l\u00e0m 2 l\u1ea7n.<\/span><\/td>\n
Lescol XL do C\u00f4ng ty Novartis AG nghi\u00ean c\u1ee9u v\u00e0 s\u1ea3n xu\u1ea5t, thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 kho\u1ea3ng 300.000VN\u0110\/h\u1ed9p.\u00a0<\/span><\/p>\n
Autifan 40<\/span> do C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m An Thi\u00ean nghi\u00ean c\u1ee9u v\u00e0 s\u1ea3n xu\u1ea5t, thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 130.000VN\u0110\/h\u1ed9p. Ngo\u00e0i ra c\u00f4ng ty c\u00f2n s\u1ea3n xu\u1ea5t Autifan 20mg.<\/span><\/p>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure><\/td>\n<\/tr>\n
Lovastatin<\/span><\/td>\n Mevacor<\/span><\/td>\n Ban \u0111\u1ea7u, 20 mg v\u1edbi b\u1eefa \u0103n t\u1ed1i.<\/span><\/p>\n
N\u1ebfu cholesterol huy\u1ebft thanh > 300 mg\/dL, b\u1eaft \u0111\u1ea7u v\u1edbi li\u1ec1u 40mg m\u1ed7i ng\u00e0y.<\/span><\/p>\n
T\u0103ng li\u1ec1u n\u1ebfu \u0111\u00e1p \u1ee9ng kh\u00f4ng \u0111\u1ee7 sau 4 tu\u1ea7n.<\/span><\/p>\n
Li\u1ec1u t\u1ed1i \u0111a: 80 mg m\u1ed7i ng\u00e0y.<\/span><\/p>\n
N\u1ebfu CrCl < 30 mL\/ph\u00fat (< 0,5 mL\/gi\u00e2y), li\u1ec1u h\u00e0ng ng\u00e0y kh\u00f4ng \u0111\u01b0\u1ee3c v\u01b0\u1ee3t qu\u00e1 20 mg.<\/span><\/td>\n
Vastanic 10<\/span> do C\u00f4ng ty TNHH d\u01b0\u1ee3c ph\u1ea9m USA – NIC (USA – NIC Pharma) nghi\u00ean c\u1ee9u v\u00e0 s\u1ea3n xu\u1ea5t. Thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 170.000VN\u0110\/h\u1ed9p.<\/span><\/p>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n
AgiFovir\u2013 F<\/span> do C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Agimexpharm nghi\u00ean c\u1ee9u v\u00e0 s\u1ea3n xu\u1ea5t.<\/span><\/p>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure><\/td>\n<\/tr>\n
Pravastatin<\/span><\/td>\n Vasten<\/span><\/td>\n Ban \u0111\u1ea7u, 10mg m\u1ed7i ng\u00e0y tr\u01b0\u1edbc khi \u0111i ng\u1ee7, kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o b\u1eefa \u0103n.<\/span><\/p>\n
T\u0103ng li\u1ec1u n\u1ebfu \u0111\u00e1p \u1ee9ng kh\u00f4ng \u0111\u1ee7 sau 4 tu\u1ea7n.<\/span><\/p>\n
Li\u1ec1u t\u1ed1i \u0111a: 40 mg m\u1ed7i ng\u00e0y, 10 mg \u1edf b\u1ec7nh nh\u00e2n r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng gan ho\u1eb7c th\u1eadn.<\/span><\/td>\n
Fasthan 20 do C\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m SaVi – Savipharm s\u1ea3n xu\u1ea5t c\u00f3 gi\u00e1 290.000 \u0111\u1ed3ng\/h\u1ed9p 30 vi\u00ean.<\/span><\/td>\n<\/tr>\n
Rosuvastatin<\/span><\/td>\n Crestor<\/span><\/td>\n Li\u1ec1u kh\u1edfi \u0111\u1ea7u l\u00e0 10-20mg\/l\u1ea7n\/ng\u00e0y. T\u0103ng li\u1ec1u n\u1ebfu \u0111\u00e1p \u1ee9ng kh\u00f4ng \u0111\u1ee7.<\/span><\/td>\n Crestor 20mg<\/span> do AstraZeneca Singapore Pte., Ltd \u0111\u01b0a ra th\u1ecb tr\u01b0\u1eddng, thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 470.000VN\u0110\/h\u1ed9p.<\/span><\/p>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n
Rosuvastatin STELLA 10mg do C\u00f4ng ty TNHH LD Stellapharm s\u1ea3n xu\u1ea5t, thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 150.000VN\u0110\/h\u1ed9p.<\/span><\/td>\n<\/tr>\n
Simvastatin<\/span><\/td>\n Lodales<\/span><\/td>\n Ban \u0111\u1ea7u, 20 mg m\u1ed7i ng\u00e0y tr\u01b0\u1edbc khi \u0111i ng\u1ee7.<\/span><\/p>\n
T\u0103ng li\u1ec1u n\u1ebfu \u0111\u00e1p \u1ee9ng kh\u00f4ng \u0111\u1ee7 sau 4 tu\u1ea7n.<\/span><\/p>\n
Li\u1ec1u t\u1ed1i \u0111a: 40mg hai l\u1ea7n m\u1ed7i ng\u00e0y, 5mg m\u1ed7i ng\u00e0y tr\u01b0\u1edbc khi \u0111i ng\u1ee7 n\u1ebfu b\u1ec7nh nh\u00e2n l\u00e0 ng\u01b0\u1eddi gi\u00e0 ho\u1eb7c b\u1ecb suy th\u1eadn n\u1eb7ng.<\/span><\/td>\n
Zocor 20mg do Merck Sharp & Dohme Ltd s\u1ea3n xu\u1ea5t, thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 270.000VN\u0110\/h\u1ed9p. Ngo\u00e0i ra, c\u00f4ng ty c\u00f2n c\u00f3 th\u00eam ch\u1ebf ph\u1ea9m Zocor 10mg.<\/span><\/p>\n
Simvastatin STADA<\/span> 20mg do C\u00f4ng ty TNHH LD Stada-Vi\u1ec7t Nam s\u1ea3n xu\u1ea5t, thu\u1ed1c hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n v\u1edbi gi\u00e1 105.000VN\u0110\/h\u1ed9p.<\/span><\/p>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
C\u01a1 ch\u1ebf: \u1ee8c ch\u1ebf HMG-CoA t\u1eeb \u0111\u00f3 l\u00e0m gi\u1ea3m LDL-cholesterol. <\/span>Tuy nhi\u00ean, t\u00e1c d\u1ee5ng h\u1ea1 triglyceride k\u00e9m h\u01a1n c\u00e1c thu\u1ed1c thu\u1ed9c nh\u00f3m d\u1eabn xu\u1ea5t acid fibric do \u0111\u00f3 \u0111\u01b0\u1ee3c l\u1ef1a ch\u1ecdn \u01b0u ti\u00ean cho nh\u1eefng b\u1ec7nh nh\u00e2n t\u0103ng cholesterol m\u00e1u type II, III, IV, V.<\/b><\/p>\n
L\u01b0u \u00fd:<\/span><\/p>\n
Kh\u00f4ng s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi suy gi\u1ea3m ch\u1ee9c n\u0103ng gan, th\u1eadn, ph\u1ee5 n\u1eef c\u00f3 thai, ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa, tr\u1ebb < 18 tu\u1ed5i do c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n b\u1ea5t th\u01b0\u1eddng \u1edf x\u01b0\u01a1ng.<\/b><\/p>\n
Vi\u1ec7c s\u1eed d\u1ee5ng d\u00e0i ng\u00e0y c\u00f3 th\u1ec3 l\u00e0m t\u0103ng transaminase m\u00e1u.<\/b><\/p>\n
Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb c\u1ea7n theo d\u00f5i ch\u1ee9c n\u0103ng gan v\u00e0 creatinin phosphokinase.<\/b><\/p>\n
Probucol<\/span><\/h3>\n
\u0110\u1eb7c \u0111i\u1ec3m:<\/span><\/p>\n
\n
Tan trong lipid.<\/span><\/li>\n
Kh\u1ea3 n\u0103ng h\u1ea5p thu k\u00e9m.<\/span><\/li>\n
Th\u1ee9c \u0103n l\u00e0m t\u0103ng h\u1ea5p thu.<\/span><\/li>\n
Do tan t\u1ed1t trong lipid n\u00ean th\u1eddi gian l\u01b0u trong c\u01a1 th\u1ec3 k\u00e9o d\u00e0i.<\/span><\/li>\n<\/ul>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng: L\u00e0m gi\u1ea3m LDL-cholesterol, kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m h\u1ea1 triglyceride.<\/span><\/p>\n
H\u1ea1 HDL-cholesterol m\u1ea1nh v\u00e0 k\u00e9o d\u00e0i n\u00ean ch\u1ec9 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb sau c\u00e1c thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u kh\u00e1c.<\/b><\/p>\n
L\u01b0u \u00fd:<\/span><\/p>\n
\n
Kh\u00f4ng s\u1eed d\u1ee5ng Probucol cho b\u1ec7nh nh\u00e2n b\u1ecb nh\u1ed3i m\u00e1u c\u01a1 tim, b\u1ec7nh nh\u00e2n c\u00f3 kho\u1ea3ng QT k\u00e9o d\u00e0i, tr\u1ebb d\u01b0\u1edbi 18 tu\u1ed5i, ph\u1ee5 n\u1eef c\u00f3 thai, ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa, ng\u01b0\u1eddi b\u1ec7nh \u0111ang \u0111i\u1ec1u tr\u1ecb b\u1eb1ng c\u00e1c thu\u1ed1c ch\u1ed1ng lo\u1ea1n nh\u1ecbp nh\u00f3m I, III, b\u1ec7nh nh\u00e2n \u0111ang s\u1eed d\u1ee5ng thu\u1ed1c tr\u1ea7m c\u1ea3m lo\u1ea1i 3 v\u00f2ng d\u1eabn xu\u1ea5t phenothiazin.<\/span><\/li>\n<\/ul>\n
D-Thyroxin<\/span><\/h3>\n
Bi\u1ec7t d\u01b0\u1ee3c: Choloxin.<\/span><\/p>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng: Gi\u00fap h\u1ea1 lipoprotein m\u00e1u m\u1ea1nh do t\u0103ng chuy\u1ec3n cholesterol th\u00e0nh acid m\u1eadt \u0111\u1ed3ng th\u1eddi t\u0103ng th\u1ea3i sterol ra kh\u1ecfi c\u01a1 th\u1ec3.<\/span><\/p>\n
D-Thyroxin \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh nh\u00e2n nh\u1ecf tu\u1ed5i c\u00f3 lipoprotein cao.<\/span><\/p>\n
L\u01b0u \u00fd: Kh\u00f4ng s\u1eed d\u1ee5ng cho b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh tim v\u00ec d\u1ec5 xu\u1ea5t hi\u1ec7n c\u01a1n nh\u1ed3i m\u00e1u c\u01a1 tim v\u00e0 c\u01a1n \u0111au v\u00f9ng tr\u01b0\u1edbc tim.<\/span><\/p>\n
Thu\u1ed1c \u1ee9c ch\u1ebf PCSK9<\/span><\/h3>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c \u1ee9c ch\u1ebf PCSK9<\/figcaption><\/figure>\n
C\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf PCSK9 ng\u0103n ch\u1eb7n c\u00e1c protein PCSK9 ph\u00e1 v\u1ee1 c\u00e1c th\u1ee5 th\u1ec3 LDL t\u1eeb \u0111\u00f3 l\u00e0m t\u0103ng s\u1ed1 l\u01b0\u1ee3ng LDL receptor gi\u00fap l\u00e0m gi\u1ea3m LDL-cholesterol.<\/span><\/p>\n
Evolocumab<\/span><\/h4>\n
Bi\u1ec7t d\u01b0\u1ee3c: Repatha.<\/span><\/p>\n
Ch\u1ec9 \u0111\u1ecbnh:<\/span><\/p>\n
\n
Ng\u01b0\u1eddi l\u1edbn m\u1eafc b\u1ec7nh tim m\u1ea1ch \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 \u0111au tim, \u0111\u1ed9t qu\u1ef5 v\u00e0 m\u1ed9t s\u1ed1 lo\u1ea1i ph\u1eabu thu\u1eadt tim.<\/span><\/li>\n
Ph\u1ed1i h\u1ee3p c\u00f9ng v\u1edbi ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang ho\u1eb7c c\u00f9ng v\u1edbi c\u00e1c lo\u1ea1i thu\u1ed1c gi\u1ea3m cholesterol kh\u00e1c \u1edf ng\u01b0\u1eddi l\u1edbn c\u00f3 m\u1ee9c cholesterol trong m\u00e1u cao \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 t\u0103ng lipid m\u00e1u nguy\u00ean ph\u00e1t (bao g\u1ed3m m\u1ed9t lo\u1ea1i cholesterol cao g\u1ecdi l\u00e0 t\u0103ng cholesterol m\u00e1u gia \u0111\u00ecnh d\u1ecb h\u1ee3p t\u1eed \u0111\u1ec3 gi\u1ea3m lipoprotein m\u1eadt \u0111\u1ed9 th\u1ea5p (LDL) ho\u1eb7c cholesterol x\u1ea5u.<\/span><\/li>\n
Ph\u1ed1i h\u1ee3p c\u00f9ng v\u1edbi ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang v\u00e0 c\u00e1c thu\u1ed1c h\u1ea1 LDL kh\u00e1c \u1edf tr\u1ebb em t\u1eeb 10 tu\u1ed5i tr\u1edf l\u00ean m\u1eafc b\u1ec7nh t\u0103ng cholesterol m\u00e1u gia \u0111\u00ecnh d\u1ecb h\u1ee3p t\u1eed \u0111\u1ec3 gi\u1ea3m cholesterol LDL.<\/span><\/li>\n
Ph\u1ed1i h\u1ee3p c\u00f9ng v\u1edbi c\u00e1c thu\u1ed1c h\u1ea1 LDL kh\u00e1c \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 10 tu\u1ed5i tr\u1edf l\u00ean m\u1eafc m\u1ed9t lo\u1ea1i cholesterol cao g\u1ecdi l\u00e0 t\u0103ng cholesterol m\u00e1u gia \u0111\u00ecnh \u0111\u1ed3ng h\u1ee3p t\u1eed, \u0111\u1ec3 gi\u1ea3m cholesterol LDL.<\/span><\/li>\n<\/ul>\n
Alirocumab<\/span><\/h4>\n
Bi\u1ec7t d\u01b0\u1ee3c: Praluent Pen, Praluent Syringe.<\/span><\/p>\n
Ch\u1ec9 \u0111\u1ecbnh:<\/span><\/p>\n
\n
Alirocumab \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u1edf ng\u01b0\u1eddi l\u1edbn m\u1eafc b\u1ec7nh tim \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 \u0111au tim , \u0111\u1ed9t qu\u1ef5 v\u00e0 m\u1ed9t s\u1ed1 lo\u1ea1i t\u00ecnh tr\u1ea1ng \u0111au ng\u1ef1c (\u0111au th\u1eaft ng\u1ef1c kh\u00f4ng \u1ed5n \u0111\u1ecbnh ) c\u1ea7n ph\u1ea3i nh\u1eadp vi\u1ec7n.<\/span><\/li>\n
Alirocumab c\u0169ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng c\u00f9ng v\u1edbi ch\u1ebf \u0111\u1ed9 \u0103n \u00edt ch\u1ea5t b\u00e9o, ri\u00eang l\u1ebb ho\u1eb7c c\u00f9ng v\u1edbi c\u00e1c lo\u1ea1i thu\u1ed1c gi\u1ea3m cholesterol kh\u00e1c (thu\u1ed1c statin) \u1edf ng\u01b0\u1eddi l\u1edbn c\u00f3 m\u1ee9c cholesterol trong m\u00e1u cao g\u1ecdi l\u00e0 t\u0103ng lipid m\u00e1u nguy\u00ean ph\u00e1t.<\/span><\/li>\n<\/ul>\n
Tuy nhi\u00ean, thu\u1ed1c \u1ee9c ch\u1ebf PCSK9 hi\u1ec7n nay v\u1eabn ch\u01b0a th\u1ef1c s\u1ef1 ph\u1ed5 bi\u1ebfn t\u1ea1i th\u1ecb tr\u01b0\u1eddng Vi\u1ec7t Nam<\/b>.<\/span><\/p>\n
C\u00e1c acid b\u00e9o kh\u00f4ng no \u0111a tr\u1ecb h\u1ecd Omega 3<\/span><\/h3>\n
Ngu\u1ed3n g\u1ed1c: C\u00f3 nhi\u1ec1u trong c\u00e1c lo\u1ea1i c\u00e1 \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00e1 ng\u1eeb, c\u00e1 h\u1ed3i,…<\/span><\/p>\n
C\u00e1c acid b\u00e9o kh\u00f4ng no \u0111a tr\u1ecb h\u1ecd Omega 3 c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m triglyceride v\u00e0 VLDL nh\u01b0ng \u00edt \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn LDL v\u00e0 HDL-cholesterol.<\/span><\/p>\n
C\u00f3 2 lo\u1ea1i acid b\u00e9o Omega 3 hay \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng l\u00e0:<\/span><\/p>\n
\n
Omega 3 acid ethyl esters (bi\u1ec7t d\u01b0\u1ee3c l\u00e0 Omacor).<\/span><\/li>\n
Omega 3 marine triglyceride (bi\u1ec7t d\u01b0\u1ee3c l\u00e0 Maxepa).<\/span><\/li>\n<\/ul>\n
T\u1ed5ng k\u1ebft c\u00e1c nh\u00f3m thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u<\/span><\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n
Nh\u00f3m thu\u1ed1c<\/span><\/td>\n T\u00e1c d\u1ee5ng<\/span><\/td>\n T\u00e1c d\u1ee5ng ph\u1ee5<\/span><\/td>\n<\/tr>\n
Statin<\/span><\/p>\n
Atorvastatin (Lipitor)<\/span><\/p>\n
Fluvastatin (Lescol XL)<\/span><\/p>\n
Lovastatin (Altoprev)<\/span><\/p>\n
Pitavastatin (Livalo)<\/span><\/p>\n
Pravastatin (Pravachol)<\/span><\/p>\n
Rosuvastatin (Crestor)<\/span><\/p>\n
Simvastatin (Zocor)<\/span><\/td>\n
Gi\u1ea3m LDL v\u00e0 ch\u1ea5t b\u00e9o trung t\u00ednh, t\u0103ng nh\u1eb9 HDL<\/span><\/td>\n \u0110au c\u01a1, t\u0103ng l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u, t\u00e1o b\u00f3n, bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y, \u0111au d\u1ea1 d\u00e0y, chu\u1ed9t r\u00fat, men gan t\u0103ng cao<\/span><\/td>\n<\/tr>\n
Thu\u1ed1c \u1ee9c ch\u1ebf h\u1ea5p thu cholesterol<\/span><\/p>\n
Ezetimibe (Zetia)<\/span><\/td>\n
Gi\u1ea3m LDL, gi\u1ea3m nh\u1eb9 ch\u1ea5t b\u00e9o trung t\u00ednh, t\u0103ng nh\u1eb9 HDL<\/span><\/td>\n \u0110au d\u1ea1 d\u00e0y, ti\u00eau ch\u1ea3y, m\u1ec7t m\u1ecfi, \u0111au nh\u1ee9c c\u01a1 b\u1eafp; tr\u00e1nh khi mang thai v\u00e0 cho con b\u00fa<\/span><\/td>\n<\/tr>\n
Thu\u1ed1c \u1ee9c ch\u1ebf PCSK9<\/span><\/p>\n
Alirocumab (Praluent)<\/span><\/p>\n
Evolocumab (Repatha)<\/span><\/td>\n
Gi\u1ea3m LDL, th\u01b0\u1eddng d\u00e0nh ri\u00eang cho nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh di truy\u1ec1n g\u00e2y ra m\u1ee9c LDL r\u1ea5t cao ho\u1eb7c nh\u1eefng ng\u01b0\u1eddi m\u1eafc b\u1ec7nh tim kh\u00f4ng th\u1ec3 dung n\u1ea1p statin ho\u1eb7c c\u00e1c lo\u1ea1i thu\u1ed1c gi\u1ea3m cholesterol kh\u00e1c<\/span><\/td>\n Ng\u1ee9a, s\u01b0ng, \u0111au ho\u1eb7c b\u1ea7m t\u00edm t\u1ea1i ch\u1ed7 ti\u00eam<\/span><\/td>\n<\/tr>\n
Ch\u1ea5t \u1ee9c ch\u1ebf lyase citrate<\/span><\/p>\n
Axit Bempedoic (Nexletol)<\/span><\/p>\n
Axit Bempedoic-ezetimibe (Nexlizet)<\/span><\/td>\n
Gi\u1ea3m LDL<\/span><\/td>\n Co th\u1eaft c\u01a1 v\u00e0 \u0111au kh\u1edbp, bao g\u1ed3m c\u1ea3 b\u1ec7nh g\u00fat c\u1ea5p t\u00ednh<\/span><\/td>\n<\/tr>\n
Ch\u1ea5t c\u00f4 l\u1eadp axit m\u1eadt<\/span><\/p>\n
Cholestyramine (Prevalite)<\/span><\/p>\n
Colesevelam (Welchol)<\/span><\/p>\n
Colestipol (Colestid)<\/span><\/td>\n
Gi\u1ea3m LDL, c\u00f3 th\u1ec3 t\u0103ng nh\u1eb9 HDL<\/span><\/td>\n T\u00e1o b\u00f3n, \u0111\u1ea7y h\u01a1i, bu\u1ed3n n\u00f4n, \u0111\u1ea7y h\u01a1i, \u1ee3 n\u00f3ng<\/span><\/td>\n<\/tr>\n
Thu\u1ed1c \u1ee9c ch\u1ebf h\u1ea5p thu cholesterol ph\u1ed1i h\u1ee3p v\u00e0 statin<\/span><\/p>\n
Ezetimibe-simvastatin (Vytorin)<\/span><\/td>\n
Gi\u1ea3m LDL v\u00e0 ch\u1ea5t b\u00e9o trung t\u00ednh, t\u0103ng HDL<\/span><\/td>\n \u0110au d\u1ea1 d\u00e0y, m\u1ec7t m\u1ecfi, \u0111\u1ea7y h\u01a1i, t\u00e1o b\u00f3n, \u0111au b\u1ee5ng, chu\u1ed9t r\u00fat, \u0111au nh\u1ee9c c\u01a1, \u0111au v\u00e0 y\u1ebfu<\/span><\/td>\n<\/tr>\n
Fibrate<\/span><\/p>\n
Fenofibrate (Antara, Lipofen, c\u00e1c lo\u1ea1i kh\u00e1c)<\/span><\/p>\n
Gemfibrozil (Lopid)<\/span><\/td>\n
Gi\u1ea3m ch\u1ea5t b\u00e9o trung t\u00ednh, gi\u1ea3m nh\u1eb9 LDL, t\u0103ng HDL<\/span><\/td>\n Bu\u1ed3n n\u00f4n, \u0111au b\u1ee5ng, \u0111au c\u01a1<\/span><\/td>\n<\/tr>\n
Niacin<\/span><\/p>\n
Thu\u1ed1c k\u00ea \u0111\u01a1n (Niacor, Niaspan)<\/span><\/td>\n
Gi\u1ea3m LDL v\u00e0 ch\u1ea5t b\u00e9o trung t\u00ednh; t\u0103ng HDL<\/span><\/td>\n \u0110\u1ecf b\u1eebng m\u1eb7t v\u00e0 c\u1ed5, ng\u1ee9a, kh\u00f3 ch\u1ecbu \u1edf d\u1ea1 d\u00e0y, t\u0103ng l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u<\/span><\/td>\n<\/tr>\n
Axit b\u00e9o omega-3<\/span><\/p>\n
C\u00e1c phi\u00ean b\u1ea3n k\u00ea \u0111\u01a1n bao g\u1ed3m Lovaza, Omacor v\u00e0 Vascepa<\/span><\/td>\n
Gi\u1ea3m ch\u1ea5t b\u00e9o trung t\u00ednh; c\u00f3 th\u1ec3 t\u0103ng HDL<\/span><\/td>\n \u1ee2 h\u01a1i, tanh, kh\u00f3 ti\u00eau; c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
M\u1ed9t s\u1ed1 thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u m\u1edbi<\/span><\/h2>\n
BMS-201038 v\u00e0 Avasimibe l\u00e0 2 thu\u1ed1c m\u1edbi \u0111ang \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng pha II v\u00e0 III \u1edf ng\u01b0\u1eddi c\u00f3 r\u1ed1i lo\u1ea1n lipoprotein.<\/span><\/p>\n
BMS-201038 l\u00e0 <\/span>thu\u1ed1c h\u1ea1 triglyceride<\/b> v\u1edbi c\u01a1 ch\u1ebf l\u00e0m gi\u1ea3m v\u1eadn chuy\u1ec3n triglyceride v\u00e0 c\u00e1c lipid kh\u00f4ng ph\u00e2n c\u1ef1c \u0111\u1ebfn apolipoprotein.<\/span><\/p>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a Avasimibe l\u00e0 l\u00e0m gi\u1ea3m s\u1ef1 ester h\u00f3a cholesterol \u1edf gan, ru\u1ed9t, \u0111\u1ea1i th\u1ef1c b\u00e0o.<\/span><\/p>\n
Th\u1ef1c ph\u1ea9m gi\u00fap h\u1ea1 m\u1ee1 m\u00e1u kh\u00f4ng c\u1ea7n d\u00f9ng thu\u1ed1c<\/span><\/h2>\n
Th\u1ef1c ph\u1ea9m h\u1ed7 tr\u1ee3 l\u00e0m h\u1ea1 m\u1ee1 m\u00e1u<\/span><\/h3>\n
Vi\u1ec7c thay \u0111\u1ed5i ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng g\u00f3p ph\u1ea7n \u0111\u00e1ng k\u1ec3 v\u00e0o vi\u1ec7c l\u00e0m h\u1ea1 m\u1ee1 m\u00e1u.<\/span><\/p>\n
\n
Gi\u1ea3m ch\u1ea5t b\u00e9o b\u00e3o h\u00f2a.<\/span><\/li>\n
Lo\u1ea1i b\u1ecf ch\u1ea5t b\u00e9o chuy\u1ec3n h\u00f3a.<\/span><\/li>\n
\u0102n th\u1ef1c ph\u1ea9m gi\u00e0u axit b\u00e9o omega-3: Axit b\u00e9o omega-3 kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng nhi\u1ec1u trong vi\u1ec7c l\u00e0m gi\u1ea3m cholesterol LDL. Tuy nhi\u00ean, axit b\u00e9o omega-3 l\u1ea1i c\u00f3 nh\u1eefng l\u1ee3i \u00edch \u0111\u00e1ng k\u1ec3 \u0111\u1ed1i v\u1edbi s\u1ee9c kh\u1ecfe tim m\u1ea1ch.<\/span><\/li>\n
T\u0103ng ch\u1ea5t x\u01a1 h\u00f2a tan c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m s\u1ef1 h\u1ea5p th\u1ee5 cholesterol v\u00e0o m\u00e1u.<\/span><\/li>\n
B\u1ed5 sung \u0111\u1ea1m whey.<\/span><\/li>\n<\/ul>\n
S\u1ea3n ph\u1ea9m h\u1ea1 m\u1ee1 m\u00e1u c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb th\u1ea3o d\u01b0\u1ee3c<\/span><\/h3>\n
T\u00e1o Gai<\/span><\/h4>\n
T\u00e1o gai r\u1ea5t gi\u00e0u c\u00e1c ch\u1ea5t c\u00f3 l\u1ee3i kh\u00e1c nhau nh\u01b0 axit t\u00e1o gai, axit tartaric, axit citric,… Nh\u1eefng th\u00e0nh ph\u1ea7n n\u00e0y g\u00f3p ph\u1ea7n l\u00e0m gi\u00e3n m\u1ea1ch m\u00e1u, gi\u1ea3m huy\u1ebft \u00e1p, h\u1ea1 m\u1ee9c cholesterol v\u00e0 t\u0103ng c\u01b0\u1eddng ho\u1ea1t \u0111\u1ed9ng c\u1ee7a c\u00e1c enzyme ti\u00eau h\u00f3a d\u1ea1 d\u00e0y.<\/span><\/p>\n
T\u00e1o gai c\u00f3 nhi\u1ec1u d\u1ea1ng kh\u00e1c nhau, bao g\u1ed3m c\u1ea3 d\u1ea1ng vi\u00ean v\u00e0 d\u1ea1ng h\u1ea1t, thu\u1eadn ti\u1ec7n cho vi\u1ec7c ti\u00eau th\u1ee5. Ngo\u00e0i ra, qu\u1ea3 t\u00e1o gai s\u1ed1ng kh\u00f4 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 pha tr\u00e0 th\u1ea3o d\u01b0\u1ee3c ho\u1eb7c thu\u1ed1c s\u1eafc, cho ph\u00e9p s\u1eed d\u1ee5ng c\u00e1c ph\u01b0\u01a1ng ph\u00e1p s\u1eed d\u1ee5ng thay th\u1ebf.<\/span><\/p>\n
H\u00e0 Th\u1ee7 \u00d4 (Polygonum multiflorum)<\/span><\/h4>\n
H\u00e0 Th\u1ee7 \u00d4 c\u00f3 th\u1ec3 th\u00fac \u0111\u1ea9y nhu \u0111\u1ed9ng ru\u1ed9t, gi\u1ea3m s\u1ef1 h\u1ea5p thu cholesterol v\u00e0 \u0111\u1ea9y nhanh qu\u00e1 tr\u00ecnh b\u00e0i ti\u1ebft cholesterol. \u0110i\u1ec1u n\u00e0y l\u00e0m cho n\u00f3 c\u00f3 hi\u1ec7u qu\u1ea3 trong vi\u1ec7c gi\u1ea3m m\u1ee9c cholesterol v\u00e0 mang l\u1ea1i l\u1ee3i \u00edch ch\u1ed1ng x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch.<\/span><\/p>\n
B\u1ea1ch qu\u1ea3<\/span><\/h4>\n
Nghi\u00ean c\u1ee9u ph\u00e1t hi\u1ec7n ra r\u1eb1ng Ginkgo biloba c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u00e3n m\u1ea1ch v\u00e0nh v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m cholesterol huy\u1ebft thanh bao g\u1ed3m cholesterol to\u00e0n ph\u1ea7n v\u00e0 ch\u1ea5t b\u00e9o trung t\u00ednh.<\/span><\/p>\n
Gi\u1ea3o C\u1ed5 Lam<\/span><\/h4>\n
Th\u00e0nh ph\u1ea7n ch\u00ednh c\u1ee7a d\u01b0\u1ee3c li\u1ec7u Gi\u1ea3o C\u1ed5 Lam l\u00e0: Saponin, Flavonoid,…<\/span><\/p>\n
V\u00e0o n\u0103m 1999 m\u1ed9t nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi t\u00e1c gi\u1ea3 Ph\u1ea1m Thanh K\u1ef3 \u0111\u00e3 th\u1ef1c hi\u1ec7n m\u1ed9t th\u1eed nghi\u1ec7m tr\u00ean chu\u1ed9t \u0111\u01b0\u1ee3c g\u00e2y r\u1ed1i lo\u1ea1n m\u1ee1 m\u00e1u. Theo \u0111\u00f3, \u0111\u1ed9ng v\u1eadt th\u1eed nghi\u1ec7m s\u1ebd \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng Gi\u1ea3o C\u1ed5 Lam li\u00ean t\u1ee5c trong 30 ng\u00e0y li\u00ean ti\u1ebfp. K\u1ebft qu\u1ea3 l\u01b0\u1ee3ng Cholesterol to\u00e0n ph\u1ea7n gi\u1ea3m 71% so v\u1edbi nh\u00f3m kh\u00f4ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng.\u00a0<\/span><\/p>\n
M\u1ed9t nghi\u00ean c\u1ee9u c\u1ee7a t\u00e1c gi\u1ea3 Samer Megalli, tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc Sydney, \u00dac c\u0169ng ch\u1ee9ng minh \u0111\u01b0\u1ee3c k\u1ebft qu\u1ea3 t\u01b0\u01a1ng t\u1ef1.<\/span><\/p>\n
Theo \u0111\u00f3 vi\u1ec7c s\u1eed d\u1ee5ng Gi\u1ea3o C\u1ed5 Lam c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 Cholesterol x\u1ea5u trong m\u00e1u, h\u1ea1n ch\u1ebf s\u1ef1 h\u00ecnh th\u00e0nh c\u1ee7a c\u00e1c m\u1ea3ng x\u01a1 v\u1eefa trong l\u00f2ng m\u1ea1ch. Hi\u1ec7u qu\u1ea3 ki\u1ec3m so\u00e1t m\u1ee1 m\u00e1u c\u1ee7a Gi\u1ea3o C\u1ed5 Lam \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi Atorvastatin.<\/span><\/p>\n
M\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m chi\u1ebft xu\u1ea5t t\u1eeb th\u1ea3o d\u01b0\u1ee3c gi\u00fap l\u00e0m gi\u1ea3m m\u1ee1 m\u00e1u<\/span><\/h3>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u ngu\u1ed3n g\u1ed1c th\u1ea3o d\u01b0\u1ee3c<\/figcaption><\/figure>\n
Thu\u1ed1c gi\u1ea3m m\u1ee1 m\u00e1u c\u1ee7a M\u1ef9 FAZ Ecogreen <\/b>do C\u00f4ng ty St. Paul Brands s\u1ea3n xu\u1ea5t c\u00f3 gi\u00e1 290.000 \u0111\u1ed3ng\/l\u1ecd 30 vi\u00ean.<\/span><\/p>\n
Hamoic Danapha Viva do D\u01b0\u1ee3c ph\u1ea9m Danapha s\u1ea3n xu\u1ea5t.<\/span><\/p>\n
M\u1ee1 m\u00e1u T\u00e2m B\u00ecnh do C\u00f4ng ty TNHH SX & TM D\u01b0\u1ee3c ph\u1ea9m T\u00e2m B\u00ecnh s\u1ea3n xu\u1ea5t.<\/span><\/p>\n
Cholesterol T\u00edn Phong do C\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Gia Nguy\u1ec5n s\u1ea3n xu\u1ea5t c\u00f3 gi\u00e1 155.000 \u0111\u1ed3ng\/l\u1ecd 30 vi\u00ean.<\/span><\/p>\n
L\u1eddi khuy\u00ean t\u1eeb d\u01b0\u1ee3c s\u0129<\/span><\/h2>\nKhi n\u00e0o c\u1ea7n u\u1ed1ng thu\u1ed1c gi\u1ea3m m\u1ee1 m\u00e1u?<\/span><\/h3>\n
Khi \u0111i\u1ec1u tr\u1ecb, b\u00e1c s\u0129 s\u1ebd xem x\u00e9t m\u1ee9c cholesterol hi\u1ec7n t\u1ea1i v\u00e0 nguy c\u01a1 m\u1eafc b\u1ec7nh tim v\u00e0 \u0111\u1ed9t qu\u1ef5 c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh \u0111\u1ec3 k\u1ebft lu\u1eadn c\u00f3 n\u00ean s\u1eed d\u1ee5ng thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u kh\u00f4ng?<\/span><\/p>\n
Thu\u1ed1c h\u1ea1 cholesterol s\u1ebd \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh n\u1ebfu:<\/span><\/p>\n
Ng\u01b0\u1eddi b\u1ec7nh \u0111\u00e3 c\u00f3 ti\u1ec1n s\u1eed \u0111au tim, \u0111\u1ed9t qu\u1ef5 ho\u1eb7c m\u1eafc b\u1ec7nh \u0111\u1ed9ng m\u1ea1ch ngo\u1ea1i bi\u00ean.<\/span><\/p>\n
Ch\u1ec9 s\u1ed1 LDL-cholesterol \u2265 190mg\/dL.<\/span><\/p>\n
B\u1ec7nh nh\u00e2n t\u1eeb 40-75 tu\u1ed5i m\u1eafc b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng v\u00e0 c\u00f3 ch\u1ec9 s\u1ed1 LDL-cholesterol \u2265 70mg\/dL.<\/span><\/p>\n
B\u1ec7nh nh\u00e2n t\u1eeb 40-75 tu\u1ed5i c\u00f3 nguy c\u01a1 cao m\u1eafc b\u1ec7nh tim m\u1ea1ch ho\u1eb7c \u0111\u1ed9t qu\u1ef5 v\u00e0 c\u00f3 ch\u1ec9 s\u1ed1 LDL-cholesterol \u2265 70mg\/dL.\u00a0<\/span><\/p>\n
Thu\u1ed1c m\u1ee1 m\u00e1u c\u00f3 ph\u1ea3i u\u1ed1ng su\u1ed1t \u0111\u1eddi kh\u00f4ng?<\/span><\/h3>\n
Vi\u1ec7c ng\u1eebng thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u c\u1ea7n c\u00f3 s\u1ef1 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129 \u0111\u1ec3 tr\u00e1nh nguy c\u01a1 t\u0103ng cholesterol qu\u00e1 m\u1ee9c.<\/span><\/p>\n
Thu\u1ed1c h\u1ea1 m\u1ee1 m\u00e1u d\u00f9ng bao l\u00e2u?<\/span><\/h3>\n
Th\u00f4ng th\u01b0\u1eddng, b\u1ec7nh nh\u00e2n s\u1ebd \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng <\/span>c\u00e1c thu\u1ed1c l\u00e0m gi\u1ea3m m\u1ee1 m\u00e1u<\/b> trong v\u00f2ng 2-3 th\u00e1ng, sau \u0111\u00f3 b\u1ec7nh nh\u00e2n s\u1ebd \u0111\u01b0\u1ee3c x\u00e9t nghi\u1ec7m m\u00e1u \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u tr\u1ecb.<\/span><\/p>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/span><\/h2>\n\n
T\u00e1c gi\u1ea3 Sanjai Sinha (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 3 th\u00e1ng 7 n\u0103m 2023), <\/span>Atorvastatin<\/span><\/i>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 24 th\u00e1ng 10 n\u0103m 2023, t\u1eeb <\/span>https:\/\/www.drugs.com\/atorvastatin.html<\/span><\/a><\/li>\n
T\u00e1c gi\u1ea3 Cerner Multum (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 26 th\u00e1ng 9 n\u0103m 2023), <\/span>Lovastatin<\/span><\/i>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 24 th\u00e1ng 10 n\u0103m 2023, t\u1eeb <\/span>https:\/\/www.drugs.com\/mtm\/lovastatin.html<\/span><\/a>\u00a0<\/span><\/li>\n
T\u00e1c gi\u1ea3 Jennifer Robinson (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 19 th\u00e1ng 7 n\u0103m 2023). <\/span>Which Medicines Lower ‘Bad’ (LDL) Cholesterol?<\/span><\/i>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 7 th\u00e1ng 11 n\u0103m 2023 t\u1eeb <\/span>https:\/\/www.webmd.com\/cholesterol-management\/cholesterol-lowering-medication<\/span><\/a>\u00a0<\/span><\/li>\n
T\u00e1c gi\u1ea3 Leigh Ann Anderson, PharmD (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 10 th\u00e1ng 10 n\u0103m 2023). <\/span>FDA-Approved Weight Loss Drugs: Can They Help You?<\/span><\/i>. Th\u1eddi gian truy c\u1eadp ng\u00e0y 7 th\u00e1ng 11 n\u0103m 2023 t\u1eeb <\/span>https:\/\/www.drugs.com\/article\/fda-approved-weight-loss-drugs.html<\/span><\/a>\u00a0<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"
T\u0103ng lipid m\u00e1u l\u00e0 m\u1ed9t trong nh\u1eefng y\u1ebfu t\u1ed1 nguy c\u01a1 ph\u00e1t tri\u1ec3n b\u1ec7nh tim m\u1ea1ch. Thu\u1ed1c h\u1ea1 lipid m\u00e1u l\u00e0 g\u00ec? C\u00f3 nh\u1eefng l\u01b0u \u00fd g\u00ec khi s\u1eed d\u1ee5ng c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y? B\u00e0i vi\u1ebft d\u01b0\u1edbi \u0111\u00e2y, D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng s\u1ebd cung c\u1ea5p cho b\u1ea1n \u0111\u1ecdc nh\u1eefng th\u00f4ng tin c\u1ea7n thi\u1ebft v\u1ec1 […]\n","protected":false},"author":1,"featured_media":55770,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-55763","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/55763","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=55763"}],"version-history":[{"count":1,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/55763\/revisions"}],"predecessor-version":[{"id":72457,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/55763\/revisions\/72457"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/55770"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=55763"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=55763"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=55763"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

Acid Nicotinic (Vitamin PP, Vitamin B3, Niacin)<\/span><\/h3>\n<\/a>Acid Nicotinic<\/figcaption><\/figure>\n\u0110\u1eb7c \u0111i\u1ec3m:<\/span><\/p>\n

Probucol<\/span><\/h3>\n\u0110\u1eb7c \u0111i\u1ec3m:<\/span><\/p>\n\nTan trong lipid.<\/span><\/li>\nKh\u1ea3 n\u0103ng h\u1ea5p thu k\u00e9m.<\/span><\/li>\nTh\u1ee9c \u0103n l\u00e0m t\u0103ng h\u1ea5p thu.<\/span><\/li>\n