{"id":54347,"date":"2023-11-02T12:08:03","date_gmt":"2023-11-02T05:08:03","guid":{"rendered":"https:\/\/vnras.com\/drug\/?p=54347"},"modified":"2024-05-06T11:06:32","modified_gmt":"2024-05-06T04:06:32","slug":"nen-lua-chon-thuoc-tri-nam-da-nao-an-toan-hieu-qua-cao","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/nen-lua-chon-thuoc-tri-nam-da-nao-an-toan-hieu-qua-cao\/","title":{"rendered":"N\u00ean l\u1ef1a ch\u1ecdn thu\u1ed1c tr\u1ecb n\u00e1m da n\u00e0o an to\u00e0n hi\u1ec7u qu\u1ea3 cao?"},"content":{"rendered":"

N\u00e1m da v\u00e0 c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 n\u00e1m lu\u00f4n l\u00e0 ch\u1ee7 \u0111\u1ec1 nh\u1eadn \u0111\u01b0\u1ee3c s\u1ef1 quan t\u00e2m c\u1ee7a nh\u1eefng ng\u01b0\u1eddi y\u00eau th\u00edch c\u00e1i \u0111\u1eb9p, c\u00f3 mong mu\u1ed1n s\u1edf h\u1eefu l\u00e0n da \u0111\u1eb9p. B\u00e0i vi\u1ebft n\u00e0y s\u1ebd \u0111\u1ec1 c\u1eadp t\u1edbi c\u00e1c lo\u1ea1i thu\u1ed1c tr\u1ecb n\u00e1m hi\u1ec7u qu\u1ea3 v\u00e0 th\u00f4ng d\u1ee5ng tr\u00ean th\u1ecb tr\u01b0\u1eddng.<\/strong><\/p>\n

T\u00ecm hi\u1ec3u v\u1ec1 n\u00e1m da<\/h2>\n
\u0110\u1ecbnh ngh\u0129a b\u1ec7nh n\u00e1m da<\/h3>\n
N\u00e1m da (Melasma) l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng t\u0103ng h\u1eafc t\u1ed1 s\u1eafc t\u1ed1 \u1edf da, ph\u1ea7n da b\u1ecb n\u00e1m th\u01b0\u1eddng l\u00e0 v\u00f9ng da ti\u1ebfp x\u00fac v\u1edbi \u00e1nh n\u1eafng m\u1eb7t tr\u1eddi. N\u00e1m th\u01b0\u1eddng th\u1ec3 hi\u1ec7n d\u01b0\u1edbi d\u1ea1ng c\u00e1c m\u1ea3ng t\u0103ng s\u1eafc t\u1ed1, \u0111\u1ed1i x\u1ee9ng, c\u00f3 \u0111\u01b0\u1eddng vi\u1ec1n kh\u00f4ng \u0111\u1ec1u, c\u00f3 r\u0103ng c\u01b0a v\u00e0 h\u00ecnh \u0111\u1ecba l\u00fd. C\u00e1c v\u1ecb tr\u00ed ph\u1ed5 bi\u1ebfn nh\u1ea5t l\u00e0 m\u00e1, m\u00f4i tr\u00ean, c\u1eb1m v\u00e0 tr\u00e1n, nh\u01b0ng nh\u1eefng v\u00f9ng ti\u1ebfp x\u00fac v\u1edbi \u00e1nh n\u1eafng kh\u00e1c \u0111\u00f4i khi c\u0169ng c\u00f3 th\u1ec3 b\u1ecb \u1ea3nh h\u01b0\u1edfng. M\u1eb7c d\u00f9 n\u00e1m c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn b\u1ea5t k\u1ef3 ch\u1ee7ng t\u1ed9c n\u00e0o, nh\u01b0ng n\u00f3 ph\u1ed5 bi\u1ebfn h\u01a1n nhi\u1ec1u \u1edf ng\u01b0\u1eddi \u0110\u00f4ng \u00c1, \u0110\u00f4ng Nam \u00c1. v\u00e0 ng\u01b0\u1eddi g\u1ed1c T\u00e2y Ban Nha s\u1ed1ng \u1edf nh\u1eefng khu v\u1ef1c tr\u00ean th\u1ebf gi\u1edbi c\u00f3 m\u1ee9c \u0111\u1ed9 ti\u1ebfp x\u00fac v\u1edbi tia c\u1ef1c t\u00edm m\u1eb7t tr\u1eddi cao.<\/p>\n
C\u01a1 ch\u1ebf h\u00ecnh th\u00e0nh n\u00e1m da c\u00f3 th\u1ec3 do nhi\u1ec1u y\u1ebfu t\u1ed1 li\u00ean quan. Hi\u1ec7n t\u1ea1i, ng\u01b0\u1eddi ta m\u1edbi x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c 2 c\u01a1 ch\u1ebf ch\u00ednh li\u00ean quan \u0111\u1ebfn vi\u1ec7c h\u00ecnh th\u00e0nh n\u00e1m. C\u01a1 ch\u1ebf g\u00e2y n\u00e1m do estrogen c\u00f3 th\u1ec3 li\u00ean quan \u0111\u1ebfn s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a c\u00e1c th\u1ee5 th\u1ec3 estrogen tr\u00ean t\u1ebf b\u00e0o h\u1eafc t\u1ed1 k\u00edch th\u00edch t\u1ebf b\u00e0o s\u1ea3n sinh ra nhi\u1ec1u Melanin h\u01a1n. C\u01a1 ch\u1ebf th\u1ee9 2 l\u00e0 tia UV s\u1ebd l\u00e0m t\u0103ng c\u00e1c h\u1eafc s\u1eafc t\u1ed1 Melanin: tia UV g\u00e2y t\u0103ng sinh t\u0103ng sinh m\u1ea1ch m\u00e1u \u1edf da v\u00e0 \u0111i\u1ec1u h\u00f2a t\u0103ng c\u00e1c y\u1ebfu t\u1ed1 t\u1ea1o m\u1ea1ch \u1edf da nh\u01b0 y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng n\u1ed9i m\u00f4 m\u1ea1ch m\u00e1u (VEGF), y\u1ebfu t\u1ed1 t\u0103ng tr\u01b0\u1edfng nguy\u00ean b\u00e0o s\u1ee3i c\u01a1 b\u1ea3n (bFGF) v\u00e0 interleukin (IL)-8), gi\u1ea3i ph\u00f3ng c\u00e1c ch\u1ea5t trung gian nh\u01b0 ch\u1ea5t chuy\u1ec3n h\u00f3a Acid arachidonic v\u00e0 plasminogen t\u1eeb c\u00e1c m\u1ea1ch t\u0103ng sinh, gi\u00fap t\u0103ng c\u01b0\u1eddng qu\u00e1 tr\u00ecnh h\u00ecnh th\u00e0nh h\u1eafc t\u1ed1 trong n\u00e1m da.<\/p>\n
M\u1ed9t s\u1ed1 nguy\u00ean nh\u00e2n d\u1eabn \u0111\u1ebfn t\u00ecnh tr\u1ea1ng n\u00e1m da c\u00f3 th\u1ec3 k\u1ec3 t\u1edbi:<\/p>\n
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N\u1ed9i ti\u1ebft t\u1ed1 thay \u0111\u1ed5i<\/li>\n
Do di truy\u1ec1n<\/li>\n
Tu\u1ed5i t\u00e1c<\/li>\n
C\u0103ng th\u1eb3ng, lo \u00e2u, stress<\/li>\n
Ch\u1ebf \u0111\u1ed9 sinh ho\u1ea1t b\u1ea5t h\u1ee3p l\u00fd, th\u01b0\u1eddng xuy\u00ean m\u1ea5t ng\u1ee7: th\u1ee9c khuya, m\u1ea5t ng\u1ee7, u\u1ed1ng nhi\u1ec1u r\u01b0\u1ee3u bia, h\u00fat thu\u1ed1c l\u00e1, kh\u00f4ng u\u1ed1ng \u0111\u1ee7 n\u01b0\u1edbc,…<\/li>\n
Th\u01b0\u1eddng xuy\u00ean ti\u1ebfp x\u00fac v\u1edbi \u00e1nh s\u00e1ng m\u1eb7t tr\u1eddi m\u00e0 kh\u00f4ng c\u00f3 bi\u1ec7n ph\u00e1p b\u1ea3o v\u1ec7 da<\/li>\n
T\u00e1c d\u1ee5ng ph\u1ee5 khi d\u00f9ng thu\u1ed1c nh\u01b0 thu\u1ed1c kh\u00e1ng sinh (Cyclin, Thiazid, Tetracyclin, Sulfamid, Chlorpromazine, Phenergan) hay thu\u1ed1c tr\u00e1nh thai,…<\/li>\n<\/ul>\n
$\"Thu\u1ed1c$ <\/a>
Nguy\u00ean nh\u00e2n g\u00e2y n\u00e1m da<\/figcaption><\/figure>\n
Ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e1m<\/h3>\n
M\u1ee5c ti\u00eau ch\u00ednh c\u1ee7a vi\u1ec7c \u0111i\u1ec1u tr\u1ecb li\u00ean quan \u0111\u1ebfn vi\u1ec7c \u1ee9c ch\u1ebf s\u1ef1 t\u0103ng sinh c\u1ee7a t\u1ebf b\u00e0o h\u1eafc t\u1ed1, h\u00ecnh th\u00e0nh Melanosome v\u00e0 th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh tho\u00e1i h\u00f3a c\u1ee7a ch\u00fang. Nh\u1eefng \u0111i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 \u0111\u1ea1t \u0111\u01b0\u1ee3c b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf s\u1ef1 t\u1ed5ng h\u1ee3p Melanin v\u00e0 ho\u1ea1t \u0111\u1ed9ng c\u1ee7a t\u1ebf b\u00e0o h\u1eafc t\u1ed1, lo\u1ea1i b\u1ecf Melanin v\u00e0 ph\u00e1 v\u1ee1 c\u00e1c h\u1ea1t Melanin c\u00f3 trong Melanosome. M\u1ed9t s\u1ed1 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb hi\u1ec7n nay l\u00e0:<\/p>\n
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Ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c\n
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\u0110i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c tr\u1ecb n\u00e1m b\u00f4i ngo\u00e0i da<\/strong><\/li>\n
\u0110i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c u\u1ed1ng tr\u1ecb n\u00e1m<\/strong><\/li>\n<\/ul>\n<\/li>\n
Li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb phi y t\u1ebf:\n\n
T\u1ea9y da ch\u1ebft h\u00f3a h\u1ecdc<\/li>\n
Laser<\/li>\n
L\u0103n kim vi \u0111i\u1ec3m<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n
B\u00e0i vi\u1ebft n\u00e0y ch\u1ec9 \u0111\u1ec1 c\u1eadp t\u1edbi ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e1m b\u1eb1ng thu\u1ed1c.<\/p>\n
C\u00f3 m\u1ea5y lo\u1ea1i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb n\u00e1m da?<\/h3>\n
M\u1ee5c ti\u00eau \u0111i\u1ec1u tr\u1ecb c\u1ee7a c\u00e1c thu\u1ed1c ch\u1eefa n\u00e1m<\/strong> th\u01b0\u1eddng l\u00e0 l\u00e0m ch\u1eadm s\u1ef1 t\u0103ng sinh t\u1ebf b\u00e0o h\u1eafc t\u1ed1, \u1ee9c ch\u1ebf s\u1ef1 h\u00ecnh th\u00e0nh Melanosome v\u00e0 th\u00fac \u0111\u1ea9y s\u1ef1 tho\u00e1i h\u00f3a c\u1ee7a ch\u00fang. M\u1ed9t s\u1ed1 c\u00e1c thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb n\u00e1m l\u00e0:<\/p>\n
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Ch\u1ea5t \u1ee9c ch\u1ebf Tyrosinase: Hydroquinone, Arbutin (\u03b1 ho\u1eb7c \u03b2 Arbutin), Acid Azelaic, Acid Kojic, Mequinol, Flavonoid,..<\/li>\n
Ch\u1ea5t \u1ee9c ch\u1ebf chuy\u1ec3n Melanosome: Niacinamide (Vit B3), Acid Retinoic,..<\/li>\n
Ch\u1ea5t ch\u1ed1ng oxy h\u00f3a: Vitamin E, Vitamin C,..<\/li>\n
Ch\u1ea5t \u1ee9c ch\u1ebf Plasmin: Acid tranexamic<\/li>\n
Gi\u1ea3m Melanin do \u03b1-MSH g\u00e2y ra: \u03b2-caroten<\/li>\n
Ch\u1ea5t \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 k\u00edch ho\u1ea1t protease-2: Ch\u1ea5t \u1ee9c ch\u1ebf trypsin \u0111\u1eadu n\u00e0nh,…<\/li>\n<\/ul>\n
C\u00e1c thu\u1ed1c \u0111\u1eb7c tr\u1ecb n\u00e1m hi\u1ec7u qu\u1ea3 hi\u1ec7n nay<\/h2>\n
Nh\u00f3m thu\u1ed1c \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p \u0111i\u1ec1u tr\u1ecb n\u00e1m<\/h3>\n
Hydroquinone<\/p>\n
Hydroquinone (HQ) hay c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 dihydroxybenzen, l\u00e0 m\u1ed9t h\u1ee3p ch\u1ea5t Hydroxy Phenolic c\u00f3 c\u1ea5u tr\u00fac t\u01b0\u01a1ng t\u1ef1 nh\u01b0 ti\u1ec1n ch\u1ea5t c\u1ee7a Melanin. N\u00f3 \u1ee9c ch\u1ebf s\u1ef1 chuy\u1ec3n \u0111\u1ed5i DOPA th\u00e0nh Melanin b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf enzyme Tyrosinase. HQ kh\u00f4ng ch\u1ec9 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 h\u00ecnh th\u00e0nh, t\u1ea1o h\u1eafc t\u1ed1 v\u00e0 tho\u00e1i h\u00f3a c\u1ee7a Melanosome m\u00e0 c\u00f2n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u1ea5u tr\u00fac m\u00e0ng c\u1ee7a t\u1ebf b\u00e0o h\u1eafc t\u1ed1 v\u00e0 cu\u1ed1i c\u00f9ng g\u00e2y ho\u1ea1i t\u1eed to\u00e0n b\u1ed9 t\u1ebf b\u00e0o h\u1eafc t\u1ed1. HQ l\u00e0 ch\u1ea5t kh\u1eed s\u1eafc t\u1ed1 \u0111\u01b0\u1ee3c k\u00ea \u0111\u01a1n th\u01b0\u1eddng xuy\u00ean nh\u1ea5t tr\u00ean to\u00e0n th\u1ebf gi\u1edbi v\u00e0 n\u00f3 v\u1eabn l\u00e0 ti\u00eau chu\u1ea9n v\u00e0ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb n\u00e1m, \u0111\u1eb7c bi\u1ec7t l\u00e0 \u1edf lo\u1ea1i bi\u1ec3u b\u00ec. T\u00e1c d\u1ee5ng l\u00e0m m\u1ea5t s\u1eafc t\u1ed1 c\u1ee7a ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb HQ tr\u1edf n\u00ean r\u00f5 r\u00e0ng sau 5-7 tu\u1ea7n. N\u00ean ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb trong \u00edt nh\u1ea5t ba th\u00e1ng, t\u1ed1i \u0111a m\u1ed9t n\u0103m. HQ c\u0169ng \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ebf k\u1ebft h\u1ee3p v\u1edbi c\u00e1c t\u00e1c nh\u00e2n kh\u00e1c nh\u01b0 kem ch\u1ed1ng n\u1eafng, Steroid b\u00f4i t\u1ea1i ch\u1ed7, Retinol v\u00e0 Acid Glycolic \u0111\u1ec3 t\u0103ng th\u00eam l\u1ee3i \u00edch.<\/p>\n
Tuy nhi\u00ean, c\u00e1c c\u01a1 quan qu\u1ea3n l\u00fd \u1edf Nh\u1eadt B\u1ea3n, Ch\u00e2u \u00c2u v\u00e0 g\u1ea7n \u0111\u00e2y nh\u1ea5t l\u00e0 Hoa K\u1ef3 \u0111\u00e3 \u0111\u1eb7t ra c\u00e2u h\u1ecfi v\u1ec1 \u0111\u1ed9 an to\u00e0n c\u1ee7a HQ v\u00e0 n\u00f3 \u0111\u00e3 b\u1ecb c\u1ea5m trong c\u00e1c ch\u1ebf ph\u1ea9m m\u1ef9 ph\u1ea9m \u1edf nhi\u1ec1u qu\u1ed1c gia. \u0110i\u1ec1u n\u00e0y \u0111\u00e3 khuy\u1ebfn kh\u00edch nghi\u00ean c\u1ee9u c\u00e1c t\u00e1c nh\u00e2n thay th\u1ebf \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb n\u00e1m t\u1ea1i ch\u1ed7.<\/p>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c tr\u1ecb n\u00e1m ch\u1ee9a Hydroquinone<\/figcaption><\/figure>\n
Ch\u1ebf ph\u1ea9m: N\u1ed3ng \u0111\u1ed9 c\u1ee7a Hydroquinone trong ch\u1ebf ph\u1ea9m b\u00f4i da th\u01b0\u1eddng l\u00e0 2-5%.<\/p>\n
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Tr\u00ean th\u1ecb tr\u01b0\u1eddng Vi\u1ec7t Nam, ng\u01b0\u1eddi d\u00f9ng c\u00f3 th\u1ec3 d\u1ec5 d\u00e0ng t\u00ecm \u0111\u01b0\u1ee3c s\u1ea3n ph\u1ea9m Phil Domina 10g ch\u1ee9a 4% Abcd v\u1edbi gi\u00e1 kho\u1ea3ng 80.000 \u0111\u1ed3ng \/ tu\u00fdp 10g. Thu\u1ed1c \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty PHIL Inter Pharma.<\/li>\n<\/ul>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n
<\/p>\n
<\/p>\n
<\/p>\n
<\/p>\n
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Skinoren ch\u1ee9a 20% Acid Azelaic \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Leo Pharmaceutical Products \u2013 \u00dd, c\u00f3 gi\u00e1 b\u00e1n tr\u00ean th\u1ecb tr\u01b0\u1eddng kho\u1ea3ng 400.000 \u0111\u1ed3ng \/ tu\u00fdp 30g.<\/li>\n<\/ul>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n\n\n\n\n
\u01afu \u0111i\u1ec3m<\/td>\n Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n
T\u00e1c d\u1ee5ng nhanh, r\u00f5 r\u1ec7t, ch\u1ec9 sau 5 – 7 tu\u1ea7n l\u00e0 ng\u01b0\u1eddi d\u00f9ng c\u00f3 th\u1ec3 th\u1ea5y \u0111\u01b0\u1ee3c s\u1ef1 bi\u1ebfn m\u1ea5t c\u1ee7a c\u00e1c v\u1ebft n\u00e1m.<\/td>\n Ho\u1ea1t ch\u1ea5t d\u1ec5 b\u1ecb oxy h\u00f3a chuy\u1ec3n m\u00e0u, v\u00e0 b\u1ecb m\u1ea5t ho\u1ea1t t\u00ednh, t\u00e1c d\u1ee5ng.<\/p>\n
Hydroquinone c\u00f3<\/strong> nhi\u1ec1u t\u00e1c d\u1ee5ng ph\u1ee5<\/strong><\/span> trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb: k\u00edch \u1ee9ng, ban \u0111\u1ecf, ch\u00e2m ch\u00edch, m\u1ee5n k\u00ea d\u1ea1ng keo, vi\u00eam da ti\u1ebfp x\u00fac d\u1ecb \u1ee9ng v\u00e0 k\u00edch \u1ee9ng, \u0111\u1ed5i m\u00e0u m\u00f3ng tay, gi\u1ea3m s\u1eafc t\u1ed1 tho\u00e1ng qua v\u00e0 t\u0103ng s\u1eafc t\u1ed1 ngh\u1ecbch l\u00fd sau vi\u00eam.<\/p>\n
S\u1eed d\u1ee5ng Hydroquinone \u1edf n\u1ed3ng \u0111\u1ed9 cao h\u01a1n 2% trong th\u1eddi gian d\u00e0i, ng\u01b0\u1eddi d\u00f9ng c\u00f3 th\u1ec3 g\u1eb7p t\u00ecnh tr\u1ea1ng Ochronosis ngo\u1ea1i sinh s\u1eafc t\u1ed1 xanh \u0111en \u1edf c\u00e1c v\u00f9ng \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Acid Tranexamic<\/h4>\n
Acid tranexamic l\u00e0 m\u1ed9t d\u1eabn ch\u1ea5t t\u1ed5ng h\u1ee3p c\u1ee7a acid amin lysine c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng ti\u00eau Fibrin, \u1ee9c ch\u1ebf s\u1ef1 ph\u00e2n h\u1ee7y Fibrin. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng ch\u1ee7 y\u1ebfu c\u1ee7a Acid Tranexamic l\u00e0 ng\u0103n c\u1ea3n Plasminogen v\u00e0 Plasmin g\u1eafn v\u00e0o Fibrin. Acid Tranexamic \u0111\u01b0\u1eddng u\u1ed1ng \u0111\u00e3 ch\u1ee9ng minh r\u00f5 r\u00e0ng hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb n\u00e1m \u1edf da ch\u00e2u \u00c1, ngay c\u1ea3 khi d\u00f9ng li\u1ec1u th\u1ea5p (v\u00ed d\u1ee5 500mg m\u1ed7i ng\u00e0y) trong th\u1eddi gian ng\u1eafn (8-12 tu\u1ea7n). N\u00f3 c\u0169ng l\u00e0 m\u1ed9t l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb an to\u00e0n, d\u1ec5 s\u1eed d\u1ee5ng v\u1edbi \u00edt t\u00e1c d\u1ee5ng ph\u1ee5 nh\u1eb9. C\u00e1c nghi\u00ean c\u1ee9u \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng Acid<\/p>\n
Tranexamic kh\u00f4ng l\u00e0m t\u0103ng nguy c\u01a1 huy\u1ebft kh\u1ed1i t\u1eafc m\u1ea1ch, m\u1eb7c d\u00f9 b\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c s\u00e0ng l\u1ecdc c\u1ea9n th\u1eadn v\u1ec1 c\u00e1c ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u00e0 c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb. Thu\u1ed1c \u0111\u01b0\u1ee3c xem x\u00e9t trong nh\u1eefng tr\u01b0\u1eddng h\u1ee3p kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u1edbi Hydroquinone t\u1ea1i ch\u1ed7 v\u00e0 li\u1ec7u ph\u00e1p t\u1ea1i ch\u1ed7 k\u1ebft h\u1ee3p trong kho\u1ea3ng th\u1eddi gian kho\u1ea3ng 12 tu\u1ea7n v\u00e0 kh\u00f4ng c\u00f3 ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u1edbi Acid Tranexamic \u0111\u01b0\u1eddng u\u1ed1ng.<\/p>\n
Ch\u1ebf ph\u1ea9m: Thu\u1ed1c tr\u1ecb n\u00e1m Transino<\/strong> l\u00e0 b\u1ed9 s\u1ea3n ph\u1ea9m \u0111\u1ea7u ti\u00ean ch\u1ee9a Acid Tranexamic \u0111\u01b0\u1ee3c x\u00e1c nh\u1eadn hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb n\u00e1m. B\u1ed9 s\u1ea3n ph\u1ea9m \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n b\u1edfi t\u1eadp \u0111o\u00e0n Daiichi Sankyo Healthcare. Transino c\u00f3 c\u1ea3 d\u1ea1ng d\u00f9ng b\u00f4i ngo\u00e0i da tr\u1ecb n\u00e1m v\u00e0 vi\u00ean u\u1ed1ng tr\u1ecb n\u00e1m t\u1eeb b\u00ean trong.<\/p>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c tr\u1ecb n\u00e1m ch\u1ee9a Acid Tranexamic<\/figcaption><\/figure>\n\n\n\n\n
\u01afu \u0111i\u1ec3m<\/td>\n Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n
Ho\u1ea1t ch\u1ea5t mang l\u1ea1i hi\u1ec7u qu\u1ea3 cao trong th\u1eddi gian ng\u1eafn (8-12 tu\u1ea7n) ch\u1ec9 v\u1edbi m\u1ee9c li\u1ec1u 500mg.<\/p>\n
Thu\u1ed1c \u0111\u1eb7c bi\u1ec7t hi\u1ec7u qu\u1ea3, \u0111\u00e1p \u1ee9ng v\u1edbi ng\u01b0\u1eddi ch\u00e2u \u00c1.<\/td>\n
Gi\u00e1 th\u00e0nh t\u01b0\u01a1ng \u0111\u1ed1i cao v\u1edbi c\u00e1c ch\u1ebf ph\u1ea9m d\u1ea1ng u\u1ed1ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb n\u00e1m. S\u1ea3n ph\u1ea9m vi\u00ean u\u1ed1ng Transamin 500mg Daiichi Sankyo c\u00f3 gi\u00e1 1.500.000 \u0111\u1ed3ng \/ h\u1ed9p 100 vi\u00ean.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Acid Azelaic<\/h4>\n
Acid Azelaic l\u00e0 m\u1ed9t Acid dicarboxylic ch\u00edn carbon t\u1ef1 nhi\u00ean, kh\u00f4ng ch\u1ee9a phenolic, b\u00e3o h\u00f2a, c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf c\u1ea1nh tranh Tyrosinase. Acid Azelaic ban \u0111\u1ea7u \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n nh\u01b0 m\u1ed9t ch\u1ea5t ch\u1ed1ng m\u1ee5n tr\u1ee9ng c\u00e1 t\u1ea1i ch\u1ed7 nh\u01b0ng do t\u00e1c d\u1ee5ng c\u1ee7a n\u00f3 \u0111\u1ed1i v\u1edbi Tyrosinase n\u00ean n\u00f3 c\u0169ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c r\u1ed1i lo\u1ea1n t\u0103ng s\u1eafc t\u1ed1 nh\u01b0 n\u00e1m. C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a n\u00f3 bao g\u1ed3m \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p DNA v\u00e0 c\u00e1c enzym ty th\u1ec3, do \u0111\u00f3 g\u00e2y ra t\u00e1c d\u1ee5ng g\u00e2y \u0111\u1ed9c t\u1ebf b\u00e0o tr\u1ef1c ti\u1ebfp \u0111\u1ed1i v\u1edbi t\u1ebf b\u00e0o h\u1eafc t\u1ed1. Acid Azelaic b\u00f4i t\u1ea1i ch\u1ed7 kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m m\u1ea5t s\u1eafc t\u1ed1 tr\u00ean da c\u00f3 s\u1eafc t\u1ed1 b\u00ecnh th\u01b0\u1eddng; t\u00ednh \u0111\u1eb7c hi\u1ec7u n\u00e0y c\u00f3 th\u1ec3 l\u00e0 do t\u00e1c d\u1ee5ng ch\u1ecdn l\u1ecdc c\u1ee7a n\u00f3 \u0111\u1ed1i v\u1edbi c\u00e1c t\u1ebf b\u00e0o h\u1eafc t\u1ed1 b\u1ea5t th\u01b0\u1eddng. N\u00f3 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ch\u1ee9ng t\u0103ng s\u1eafc t\u1ed1 sau vi\u00eam trong m\u1ee5n tr\u1ee9ng c\u00e1. C\u00e1c g\u1ed1c t\u1ef1 do \u0111\u01b0\u1ee3c cho l\u00e0 g\u00f3p ph\u1ea7n l\u00e0m t\u0103ng s\u1eafc t\u1ed1 v\u00e0 Acid Azelaic ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch gi\u1ea3m s\u1ea3n xu\u1ea5t g\u1ed1c t\u1ef1 do. S\u1ef1 k\u1ebft h\u1ee3p c\u1ee7a Acid Azelaic v\u1edbi 0,05% Tretinoin ho\u1eb7c 15-20% Acid Glycolic c\u00f3 th\u1ec3 t\u1ea1o ra l\u00e0n da s\u00e1ng s\u1edbm h\u01a1n v\u00e0 r\u00f5 r\u1ec7t h\u01a1n.<\/p>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c tr\u1ecb n\u00e1m ch\u1ee9a Acid Azelaic<\/figcaption><\/figure>\n
Ch\u1ebf ph\u1ea9m:<\/p>\n
\n
Skinoren ch\u1ee9a 20% Acid Azelaic \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Leo Pharmaceutical Products \u2013 \u00dd, c\u00f3 gi\u00e1 b\u00e1n tr\u00ean th\u1ecb tr\u01b0\u1eddng kho\u1ea3ng 400.000 \u0111\u1ed3ng \/ tu\u00fdp 30g.<\/li>\n<\/ul>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n
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Derma forte ch\u1ee9a 20% Acid Azelaic c\u00f3 gi\u00e1 dao \u0111\u1ed9ng kho\u1ea3ng t\u1eeb 93.000 VND \u2013 105.000 VND\/tu\u00fdp 15g.<\/li>\n<\/ul>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n\n\n\n\n
\u01afu \u0111i\u1ec3m<\/td>\n Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n
Thu\u1ed1c c\u00f3 hi\u1ec7u qu\u1ea3 ch\u1ecdn l\u1ecdc, ch\u1ec9 c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ed9c t\u1ebf b\u00e0o h\u1eafc s\u1eafc t\u1ed1, kh\u00f4ng l\u00e0m \u1ea3nh h\u01b0\u1edfng t\u1edbi t\u1ebf b\u00e0o th\u01b0\u1eddng.<\/p>\n
Thu\u1ed1c t\u00e1c d\u1ee5ng t\u1ed1t, 20% Acid Azelaic t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi t\u00e1c d\u1ee5ng c\u1ee7a 4% Hydroquinone m\u00e0 kh\u00f4ng mang l\u1ea1i nhi\u1ec1u t\u00e1c d\u1ee5ng ph\u1ee5 b\u1ea5t l\u1ee3i.<\/td>\n
T\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a Acid Azelaic bao g\u1ed3m ng\u1ee9a, ban \u0111\u1ecf nh\u1eb9 v\u00e0 n\u00f3ng r\u00e1t.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Acid Kojic<\/h4>\n
Acid Kojic (5-hydroxy-2-hydroxymethyl-4-pyrone) l\u00e0 m\u1ed9t s\u1ea3n ph\u1ea9m n\u1ea5m \u01b0a n\u01b0\u1edbc t\u1ef1 nhi\u00ean c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb m\u1ed9t s\u1ed1 lo\u00e0i Acetobacter , Aspergillus v\u00e0 Penicillium . N\u00f3 ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf s\u1ea3n xu\u1ea5t Tyrosinase t\u1ef1 do; n\u00f3 c\u0169ng l\u00e0 m\u1ed9t ch\u1ea5t ch\u1ed1ng oxy h\u00f3a m\u1ea1nh. N\u00f3i chung n\u00f3 kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng g\u00ec v\u1edbi c\u00e1c li\u1ec7u ph\u00e1p kh\u00e1c nh\u01b0ng c\u00f3 th\u1ec3 g\u00e2y kh\u00f3 ch\u1ecbu h\u01a1n. Acid Kojic (KA) \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u1edf n\u1ed3ng \u0111\u1ed9 t\u1eeb 1 \u0111\u1ebfn 4%. KA 2% k\u1ebft h\u1ee3p v\u1edbi HQ 2% \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 v\u01b0\u1ee3t tr\u1ed9i h\u01a1n Acid Glycolic (GA) 10% v\u00e0 HQ 2%. KA c\u00f3 th\u1ec3 hi\u1ec7u qu\u1ea3 n\u1ebfu b\u1ec7nh nh\u00e2n g\u1eb7p kh\u00f3 kh\u0103n trong vi\u1ec7c dung n\u1ea1p c\u00e1c li\u1ec7u ph\u00e1p \u0111\u1ea7u tay kh\u00e1c.<\/p>\n
Ch\u1ebf ph\u1ea9m:<\/p>\n
\n
Kem Fixderma Skarfix-Tx Cream c\u00f3 ch\u1ee9a Acid Kojic v\u00e0 c\u00e1c ch\u1ea5t kh\u00e1c nh\u01b0 Tranexamic Acid, Vitamin C,.. c\u00f3 gi\u00e1 h\u01a1n 200.000 \u0111\u1ed3ng – tu\u00fdp 15g. S\u1ea3n ph\u1ea9m c\u00f3 xu\u1ea5t x\u1ee9 t\u1eeb \u1ea4n \u0110\u1ed9.<\/li>\n<\/ul>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c tr\u1ecb n\u00e1m ch\u1ee9a Acid Kojic<\/figcaption><\/figure>\n\n\n\n\n
\u01afu \u0111i\u1ec3m<\/td>\n Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n
Hi\u1ec7u qu\u1ea3 t\u1ed1t v\u1edbi c\u00e1c tr\u01b0\u1eddng h\u1ee3p kh\u00f4ng \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u tr\u1ecb tr\u01b0\u1edbc \u0111\u00f3.<\/p>\n
C\u00f3 t\u00e1c d\u1ee5ng m\u1ea1nh h\u01a1n so v\u1edbi Acid Glycolic.<\/td>\n
Acid Kojic c\u00f3 th\u1ec3 g\u00e2y vi\u00eam da ti\u1ebfp x\u00fac v\u00e0 ban \u0111\u1ecf cho ng\u01b0\u1eddi s\u1eed d\u1ee5ng.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Retinoid<\/h4>\n
Retinoids nh\u01b0 Tretinoin, l\u1ea7n \u0111\u1ea7u ti\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p v\u1edbi HQ nh\u01b0 ch\u1ea5t t\u0103ng c\u01b0\u1eddng th\u00e2m nh\u1eadp, nh\u01b0ng sau \u0111\u00f3 \u0111\u01b0\u1ee3c c\u00f4ng nh\u1eadn l\u00e0 c\u00f3 t\u00e1c d\u1ee5ng ri\u00eang \u0111\u1ed1i v\u1edbi s\u1ef1 h\u00ecnh th\u00e0nh h\u1eafc t\u1ed1. Retinoids \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn nhi\u1ec1u b\u01b0\u1edbc trong qu\u00e1 tr\u00ecnh t\u1ea1o h\u1eafc t\u1ed1. Tretinoin th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh m\u1ea5t s\u1eafc t\u1ed1 nhanh ch\u00f3ng th\u00f4ng qua qu\u00e1 tr\u00ecnh t\u1ea1o bi\u1ec3u b\u00ec v\u00e0 t\u0103ng t\u1ed1c \u0111\u1ed9 lu\u00e2n chuy\u1ec3n bi\u1ec3u b\u00ec l\u00e0m gi\u1ea3m th\u1eddi gian ti\u1ebfp x\u00fac gi\u1eefa t\u1ebf b\u00e0o s\u1eebng v\u00e0 t\u1ebf b\u00e0o h\u1eafc t\u1ed1. Acid Retinoic (RA) ng\u0103n ch\u1eb7n s\u1eafc t\u1ed1 do UVB g\u00e2y ra b\u1eb1ng c\u00e1ch gi\u1ea3m ho\u1ea1t \u0111\u1ed9ng c\u1ee7a Tyrosinase. Acid ho\u1ea1t \u0111\u1ed9ng \u1edf m\u1ee9c \u0111\u1ed9 sau phi\u00ean m\u00e3 \u0111\u1ed1i v\u1edbi Tyrosinase v\u00e0 protein li\u00ean quan \u0111\u1ebfn Tyrosinase. So v\u1edbi c\u00e1c h\u1ee3p ch\u1ea5t phenolic nh\u01b0 HQ, RA m\u1ea5t nhi\u1ec1u th\u1eddi gian h\u01a1n \u0111\u1ec3 ho\u1ea1t \u0111\u1ed9ng; t\u00ecnh tr\u1ea1ng l\u00e0m s\u00e1ng da c\u00f3 \u00fd ngh\u0129a l\u00e2m s\u00e0ng tr\u1edf n\u00ean r\u00f5 r\u00e0ng sau 24 tu\u1ea7n.<\/p>\n
\u0110\u01a1n tr\u1ecb li\u1ec7u Tretinoin \u0111\u00e3 t\u1ea1o ra \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u tr\u1ecb t\u1ed1t trong c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng nh\u01b0ng k\u1ebft qu\u1ea3 t\u1ed1t h\u01a1n thu \u0111\u01b0\u1ee3c khi k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c nh\u01b0 HQ v\u00e0 Corticosteroid.<\/p>\n
Adapalene, m\u1ed9t d\u1eabn xu\u1ea5t c\u1ee7a Acid naphthoic c\u00f3 ho\u1ea1t t\u00ednh retinoid, \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n l\u00e0 c\u00f3 hi\u1ec7u qu\u1ea3 t\u01b0\u01a1ng \u0111\u01b0\u01a1ng trong m\u1ed9t th\u1eed nghi\u1ec7m ng\u1eabu nhi\u00ean \u1edf b\u1ec7nh nh\u00e2n \u1ea4n \u0110\u1ed9 nh\u01b0ng c\u00f3 \u00edt t\u00e1c d\u1ee5ng ph\u1ee5 h\u01a1n \u0111\u00e1ng k\u1ec3 so v\u1edbi Tretinoin.<\/p>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c tr\u1ecb n\u00e1m ch\u1ee9a Retinoids<\/figcaption><\/figure>\n
Ch\u1ebf ph\u1ea9m:<\/p>\n
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Anapa ch\u1ee9a 0,0125% Tretinoin c\u00f3 gi\u00e1 b\u00e1n 70.000 \u0111\u00f4ng \/ tu\u00fdp 20g. Thu\u1ed1c \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Tr\u00e1ch nhi\u1ec7m h\u1eefu h\u1ea1n Phil Inter Pharma Vi\u1ec7t Nam.<\/li>\n<\/ul>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n
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Differin xu\u1ea5t x\u1ee9 t\u1eeb Ph\u00e1p, ch\u1ee9a 0.1% Adapalene c\u00f3 gi\u00e1 280.000 \u0111\u1ed3ng \/ tu\u00fdp 30g<\/li>\n<\/ul>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n\n\n\n\n
\u01afu \u0111i\u1ec3m<\/td>\n Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n
Thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng t\u01b0\u01a1ng \u0111\u1ed1i t\u1ed1t, c\u00f3 th\u1ec3 k\u1ebft h\u1ee3p v\u1edbi Hydroquinone v\u00e0 Steroids.<\/td>\n C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p nh\u1ea5t bao g\u1ed3m ban \u0111\u1ecf, n\u00f3ng r\u00e1t, ch\u00e2m ch\u00edch, kh\u00f4 v\u00e0 \u0111\u00f3ng v\u1ea3y. T\u00ecnh tr\u1ea1ng vi\u00eam c\u00f3 th\u1ec3 g\u00e2y t\u0103ng s\u1eafc t\u1ed1, \u0111\u1eb7c bi\u1ec7t \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 l\u00e0n da s\u1eabm m\u00e0u. Ng\u01b0\u1eddi d\u00f9ng c\u1ea7n ph\u1ea3i s\u1eed d\u1ee5ng kem ch\u1ed1ng n\u1eafng trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Retinoids.<\/p>\n
Ph\u1ee5 n\u1eef c\u00f3 thai ho\u1eb7c ng\u01b0\u1eddi c\u00f3 d\u1ef1 \u0111\u1ecbnh mang thai trong th\u1eddi gian < 1 th\u00e1ng, Retinoids l\u00e0 d\u1eabn xu\u1ea5t Vitamin A, c\u00f3 th\u1ec3 g\u00e2y d\u1ecb t\u1eadt thai nhi.<\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Steroid t\u1ea1i ch\u1ed7<\/h4>\n
T\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb n\u00e1m c\u1ee7a Corticoid th\u1eadt ra b\u1eaft ngu\u1ed3n t\u1eeb m\u1ed9t t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u1ee7a thu\u1ed1c. S\u1eed d\u1ee5ng Corticoid k\u00e9o d\u00e0i c\u00f3 th\u1ec3 d\u1eabn t\u1edbi s\u1ef1 gi\u1ea3m s\u1eafc t\u1ed1 c\u00f3 th\u1ec3 \u0111\u1ea3o ng\u01b0\u1ee3c \u1edf da b\u00ecnh th\u01b0\u1eddng. T\u1ebf b\u00e0o h\u1eafc t\u1ed1 ph\u1ea3n \u1ee9ng v\u1edbi nhi\u1ec1u lo\u1ea1i ch\u1ea5t trung gian h\u00f3a h\u1ecdc.<\/p>\n
T\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf c\u1ee7a Corticosteroid \u0111\u1ed1i v\u1edbi qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p c\u00e1c ch\u1ea5t trung gian nh\u01b0 prostaglandin v\u00e0 leukotriene c\u00f3 th\u1ec3 gi\u1ea3i th\u00edch ph\u1ea7n n\u00e0o t\u00e1c d\u1ee5ng c\u1ee7a ch\u00fang \u0111\u1ed1i v\u1edbi s\u1ef1 h\u00ecnh th\u00e0nh h\u1eafc t\u1ed1. Steroid m\u1ea1nh ho\u1eb7c si\u00eau m\u1ea1nh, khi s\u1eed d\u1ee5ng \u0111\u01a1n \u0111\u1ed9c, c\u00f3 li\u00ean quan \u0111\u1ebfn \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u tr\u1ecb t\u1ed1t, nh\u01b0ng \u0111\u01a1n tr\u1ecb li\u1ec7u th\u00ec kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn kh\u00edch do t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n th\u01b0\u1eddng g\u1eb7p c\u1ee7a thu\u1ed1c.<\/p>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c tr\u1ecb n\u00e1m ch\u1ee9a Corticoids<\/figcaption><\/figure>\n
Ch\u1ebf ph\u1ea9m:<\/p>\n
\n
Silkron ch\u1ee9a Betamethasone c\u00f3 gi\u00e1 25.000 \u0111\u1ed3ng \/ tu\u00fdp 10g, thu\u1ed1c c\u00f3 xu\u1ea5t x\u1ee9 H\u00e0n Qu\u1ed1c.<\/li>\n<\/ul>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n
<\/p>\n
<\/p>\n
<\/p>\n
<\/p>\n
\n
AtcoBeta-S ch\u1ee9a Betamethasone: 0,5mg.v\u00e0 Acid Salicylic: 30mg c\u00f3 gi\u00e1 65.000 \u0111\u1ed3ng \/ tu\u00fdp 15g. Thu\u1ed1c \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Atco Laboratories Ltd – Pakistan.<\/li>\n<\/ul>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n\n\n\n\n
\u01afu \u0111i\u1ec3m<\/td>\n Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n
Steroid b\u00f4i t\u1ea1i ch\u1ed7 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong c\u00e1c s\u1ea3n ph\u1ea9m k\u1ebft h\u1ee3p v\u00ec t\u00e1c d\u1ee5ng hi\u1ec7p \u0111\u1ed3ng v\u00e0 gi\u1ea3m k\u00edch \u1ee9ng do c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c nh\u01b0 Tretinoin g\u00e2y ra.<\/td>\n Corticoid kh\u00f4ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u01a1n \u0111\u1ed9c trong \u0111i\u1ec1u tr\u1ecb n\u00e1m<\/strong><\/span> v\u00ec thu\u1ed1c c\u00f3 nhi\u1ec1u t\u00e1c d\u1ee5ng ph\u1ee5 khi s\u1eed d\u1ee5ng l\u00e2u d\u00e0i k\u1ec3 c\u1ea3 qua \u0111\u01b0\u1eddng b\u00f4i hay \u0111\u01b0\u1eddng u\u1ed1ng.<\/p>\n
T\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a steroid t\u1ea1i ch\u1ed7 bao g\u1ed3m k\u00edch \u1ee9ng, b\u1ec7nh da li\u1ec5u gi\u1ed1ng b\u1ec7nh rosacea, teo da, gi\u00e3n mao m\u1ea1ch v\u00e0 r\u1eadm l\u00f4ng.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Acid Glycolic<\/h4>\n
Acid Glycolic l\u00e0 m\u1ed9t Acid alpha-hydroxy th\u01b0\u1eddng \u0111\u01b0\u1ee3c k\u1ebft h\u1ee3p v\u1edbi c\u00e1c ch\u1ea5t kh\u00e1c \u1edf n\u1ed3ng \u0111\u1ed9 5-10% \u0111\u1ec3 l\u00e0m s\u00e1ng da. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a n\u00f3 c\u00f3 th\u1ec3 l\u00e0 do t\u00e1i t\u1ea1o bi\u1ec3u b\u00ec v\u00e0 t\u0103ng t\u1ed1c \u0111\u1ed9 bong tr\u00f3c, d\u1eabn \u0111\u1ebfn s\u1ef1 ph\u00e2n t\u00e1n s\u1eafc t\u1ed1 nhanh ch\u00f3ng tr\u00ean c\u00e1c t\u1ed5n th\u01b0\u01a1ng s\u1eafc t\u1ed1. N\u00f3 c\u0169ng tr\u1ef1c ti\u1ebfp l\u00e0m gi\u1ea3m s\u1ef1 h\u00ecnh th\u00e0nh Melanin trong t\u1ebf b\u00e0o h\u1eafc t\u1ed1 b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf Tyrosinase.<\/p>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c tr\u1ecb n\u00e1m ch\u1ee9a Acid Glycolic<\/figcaption><\/figure>\n
Ch\u1ebf ph\u1ea9m:<\/p>\n
\n
Wortie Liquid c\u00f3 gi\u00e1 385.000 \u0111\u1ed3ng\/ l\u1ecd 5ml ch\u1ee9a 30% Acid Glycolic. Thu\u1ed1c \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Trimb Healthcare\/You Medical B.V \u2013 H\u00e0 Lan.<\/li>\n<\/ul>\n
$\"\u0110\u1eb7t$ <\/a>
\u0110\u1eb7t h\u00e0ng<\/figcaption><\/figure>\n
<\/p>\n
<\/p>\n
<\/p>\n
<\/p>\n
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Kem d\u01b0\u1ee1ng L’Oreal Paris Glycolic (AHA) Bright c\u00f3 gi\u00e1 h\u01a1n 300.000 \u0111\u1ed3ng \/ l\u1ecd 50ml. S\u1ea3n ph\u1ea9m thu\u1ed9c th\u01b0\u01a1ng hi\u1ec7u L’Oreal Paris, kh\u00e1 d\u1ec5 t\u00ecm mua t\u1ea1i c\u00e1c c\u1eeda h\u00e0ng m\u1ef9 ph\u1ea9m, si\u00eau th\u1ecb t\u1ea1i Vi\u1ec7t Nam.<\/li>\n<\/ul>\n\n\n\n\n
\u01afu \u0111i\u1ec3m<\/td>\n Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n
10% Acid Glycolic khi \u0111\u01b0\u1ee3c k\u1ebft h\u1ee3p v\u1edbi Hydroquinone mang l\u1ea1i t\u00e1c d\u1ee5ng hi\u1ec7u qu\u1ea3 \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi b\u1ecb n\u00e1m.<\/td>\n Acid Glycolic c\u00f3 m\u1ed9t t\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p \u0111\u00f3 l\u00e0 g\u00e2y k\u00edch \u1ee9ng da. Tuy nhi\u00ean v\u1ea5n \u0111\u1ec1 n\u00e0y c\u00f3 th\u1ec3 x\u1eed tr\u00ed b\u1eb1ng c\u00e1ch t\u1ea1m ng\u01b0ng d\u00f9ng v\u00e0 s\u1eed d\u1ee5ng kem d\u01b0\u1ee1ng \u1ea9m.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Mequinol<\/h4>\n
Mequinol (4-hydroxyanisole, Hydroquinone monomethyl ether) l\u00e0 m\u1ed9t d\u1eabn xu\u1ea5t c\u1ee7a HQ. C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a n\u00f3 kh\u00f4ng r\u00f5 r\u00e0ng; tuy nhi\u00ean, l\u00e0 ch\u1ea5t n\u1ec1n c\u1ee7a Tyrosinase, n\u00f3 c\u00f3 th\u1ec3 ho\u1ea1t \u0111\u1ed9ng nh\u01b0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf c\u1ea1nh tranh s\u1ef1 h\u00ecnh th\u00e0nh ti\u1ec1n ch\u1ea5t Melanin N\u00f3 hi\u1ec7n \u0111\u01b0\u1ee3c b\u00e1n tr\u00ean th\u1ecb tr\u01b0\u1eddng \u1edf Hoa K\u1ef3 v\u1edbi n\u1ed3ng \u0111\u1ed9 2% k\u1ebft h\u1ee3p v\u1edbi 0,01% Tretinoin nh\u01b0 m\u1ed9t ch\u1ea5t t\u0103ng c\u01b0\u1eddng th\u00e2m nh\u1eadp. Dung d\u1ecbch Mequinol 2%\/Tretinoin 0,01% \u0111\u01b0\u1ee3c cho l\u00e0 c\u00f3 hi\u1ec7u qu\u1ea3 cao v\u00e0 dung n\u1ea1p t\u1ed1t trong \u0111i\u1ec1u tr\u1ecb c\u00e1c v\u1ebft th\u00e2m n\u00e1m v\u00e0 c\u00e1c t\u1ed5n th\u01b0\u01a1ng t\u0103ng s\u1eafc t\u1ed1 li\u00ean quan, v\u01b0\u1ee3t tr\u1ed9i h\u01a1n HQ 3% \u0111\u1ed1i v\u1edbi c\u00e1c t\u1ed5n th\u01b0\u01a1ng \u1edf c\u1eb3ng tay v\u00e0 c\u00f3 hi\u1ec7u qu\u1ea3 t\u01b0\u01a1ng t\u1ef1 \u0111\u1ed1i v\u1edbi c\u00e1c t\u1ed5n th\u01b0\u01a1ng tr\u00ean m\u1eb7t. Ng\u01b0\u1eddi b\u1ec7nh b\u1ecb n\u00e1m c\u00f3 th\u1ec3 kh\u1ecfi ho\u00e0n to\u00e0n sau 12 tu\u1ea7n. T\u00e1c d\u1ee5ng ph\u1ee5 r\u1ea5t \u00edt v\u00e0 bao g\u1ed3m c\u1ea3m gi\u00e1c ch\u00e2m ch\u00edch \u1edf m\u1ed9t b\u1ec7nh nh\u00e2n. T\u1ea5t c\u1ea3 b\u1ec7nh nh\u00e2n \u0111\u1ec1u duy tr\u00ec k\u1ebft qu\u1ea3 \u1edf l\u1ea7n t\u00e1i kh\u00e1m sau 16 tu\u1ea7n.<\/p>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c tr\u1ecb n\u00e1m ch\u1ee9a Mequinol<\/figcaption><\/figure>\n\n\n\n\n
\u01afu \u0111i\u1ec3m<\/td>\n Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n
\u0110\u00e2y l\u00e0 m\u1ed9t ch\u1ea5t tri\u1ec3n v\u1ecdng trong \u0111i\u1ec1u tr\u1ecb n\u00e1m, d\u00f9ng k\u1ebft h\u1ee3p v\u1edbi Tretinoin mang l\u1ea1i hi\u1ec7u qu\u1ea3 t\u1ed1t.<\/p>\n
Thu\u1ed1c t\u01b0\u01a1ng \u0111\u1ed1i \u00edt t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n so v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c c\u00f3 c\u00f9ng hi\u1ec7u qu\u1ea3.<\/td>\n
Nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u1ee7a Mequinol\/Tretinoin t\u1ea1i ch\u1ed7, b\u00f4i hai l\u1ea7n m\u1ed7i ng\u00e0y trong t\u1ed1i \u0111a 24 tu\u1ea7n v\u1edbi kem ch\u1ed1ng n\u1eafng l\u00e0 n\u1ed5i ban \u0111\u1ecf, n\u00f3ng r\u00e1t\/ch\u00e2m ch\u00edch\/ng\u1ee9a ran, bong v\u1ea3y, ng\u1ee9a, k\u00edch \u1ee9ng da, gi\u1ea3m s\u1eafc t\u1ed1 qu\u1ea7ng v\u00e0 gi\u1ea3m s\u1eafc t\u1ed1.<\/p>\n
Ch\u1ebf ph\u1ea9m ch\u1ee9a ho\u1ea1t ch\u1ea5t n\u00e0y kh\u00f4ng th\u00f4ng d\u1ee5ng t\u1ea1i Vi\u1ec7t Nam, r\u1ea5t kh\u00f3 \u0111\u1ec3 c\u00f3 th\u1ec3 t\u00ecm mua.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Arbutin<\/h4>\n
Arbutin, d\u1eabn xu\u1ea5t beta -D-glucopyranoside c\u1ee7a Hydroquinone, l\u00e0 m\u1ed9t s\u1ea3n ph\u1ea9m th\u1ef1c v\u1eadt t\u1ef1 nhi\u00ean \u0111\u00e3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng th\u00e0nh c\u00f4ng trong \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n t\u0103ng s\u1eafc t\u1ed1. Li\u00ean k\u1ebft glycosid b\u1ecb th\u1ee7y ph\u00e2n in vivo d\u1eabn \u0111\u1ebfn vi\u1ec7c gi\u1ea3i ph\u00f3ng Hydroquinone c\u00f3 ki\u1ec3m so\u00e1t.<\/p>\n
Arbutin ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf Tyrosinase, do \u0111\u00f3 l\u00e0m gi\u1ea3m s\u1ef1 h\u00ecnh th\u00e0nh Melanin. H\u1ec7 vi sinh b\u00ecnh th\u01b0\u1eddng c\u1ee7a da c\u0169ng c\u00f3 th\u1ec3 th\u1ee7y ph\u00e2n Arbutin; Hydroquinone th\u1ee7y ph\u00e2n cho th\u1ea5y ho\u1ea1t t\u00ednh nh\u1eb7t g\u1ed1c t\u1ef1 do v\u00e0 \u1ee9c ch\u1ebf Tyrosinase m\u1ea1nh h\u01a1n Arbutin.<\/p>\n
T\u00e1c d\u1ee5ng c\u1ee7a Arbutin ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec1u l\u01b0\u1ee3ng v\u00e0 \u00edt \u0111\u1ed9c h\u01a1n Hydroquinone. DeoxyArbutin l\u00e0 m\u1ed9t d\u1eabn xu\u1ea5t \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n g\u1ea7n \u0111\u00e2y c\u1ee7a Arbutin, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1eb1ng c\u00e1ch lo\u1ea1i b\u1ecf c\u00e1c nh\u00f3m hydroxyl kh\u1ecfi ph\u00e2n t\u1eed. \u0110i\u1ec1u n\u00e0y t\u1ea1o ra s\u1ef1 l\u00e0m s\u00e1ng da c\u00f3 th\u1ec3 \u0111\u1ea3o ng\u01b0\u1ee3c b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf tr\u1ef1c ti\u1ebfp Tyrosinase. C\u00e1c nghi\u00ean c\u1ee9u th\u1eed nghi\u1ec7m in vitro v\u00e0 in vivo ban \u0111\u1ea7u \u0111\u00e3 ch\u1ee9ng minh r\u1eb1ng n\u00f3 c\u00f3 th\u1ec3 l\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 cho c\u00e1c r\u1ed1i lo\u1ea1n t\u0103ng s\u1eafc t\u1ed1.<\/p>\n
Ch\u1ebf ph\u1ea9m:<\/p>\n
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Kem tr\u1ecb n\u00e1m ch\u1ee9a Arbutin Obagi Clear Fx c\u00f3 gi\u00e1 kho\u1ea3ng 1.500.000 \u0111\u1ed3ng \/ l\u1ecd kho\u1ea3ng 60g. S\u1ea3n ph\u1ea9m c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb M\u1ef9 v\u1edbi c\u00f4ng ngh\u1ec7 hi\u1ec7n \u0111\u1ea1i v\u00e0 c\u00f3 ti\u1ebfng t\u0103m trong gi\u1edbi l\u00e0m \u0111\u1eb9p<\/li>\n
Serum tr\u1ecb n\u00e1m ch\u1ee9a Arbutin The Ordinary Alpha Arbutin 2% + HA c\u00f3 gi\u00e1 kho\u1ea3ng 300.000 \u0111\u1ed3ng \/ l\u1ecd 30ml. \u0110\u00e2y c\u0169ng l\u00e0 th\u01b0\u01a1ng hi\u1ec7u quen thu\u1ed9c v\u1edbi h\u1ed9i m\u00ea d\u01b0\u1ee1ng da.<\/li>\n<\/ul>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c tr\u1ecb n\u00e1m ch\u1ee9a Arbutin<\/figcaption><\/figure>\n\n\n\n\n
\u01afu \u0111i\u1ec3m<\/td>\n Nh\u01b0\u1ee3c \u0111i\u1ec3m<\/td>\n<\/tr>\n
Arbutin c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m s\u00e1ng da, lo\u1ea1i b\u1ecf c\u00e1c h\u1eafc s\u1eafc t\u1ed1 m\u1ed9t c\u00e1ch hi\u1ec7u qu\u1ea3.<\/p>\n
Arbutin tuy l\u00e0 d\u1eabn ch\u1ea5t c\u1ee7a Hydroquinone nh\u01b0ng l\u1ea1i \u00edt \u0111\u1ed9c t\u00ednh h\u01a1n h\u1eb3n so v\u1edbi HQ.<\/td>\n
C\u00f2n thi\u1ebfu c\u00e1c d\u1eef li\u1ec7u nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng \u0111\u1ec3 c\u00f3 th\u1ec3 \u0111\u1ea3m b\u1ea3o t\u00ednh hi\u1ec7u qu\u1ea3 c\u1ee7a Arbutin.<\/p>\n
Gi\u00e1 th\u00e0nh c\u1ee7a ch\u1ebf ph\u1ea9m ch\u1ee9a Arbutin t\u01b0\u01a1ng \u0111\u1ed1i cao.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
C\u00e1c thu\u1ed1c c\u00f3 tri\u1ec3n v\u1ecdng \u0111ang \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n<\/h3>\n
B\u00ean c\u1ea1nh c\u00e1c thu\u1ed1c \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p trong \u0111i\u1ec1u tr\u1ecb, c\u00e1c nh\u00e0 d\u01b0\u1ee3c l\u00fd, h\u00f3a d\u01b0\u1ee3c v\u1eabn \u0111ang nghi\u00ean c\u1ee9u ph\u00e1t tri\u1ec3n nhi\u1ec1u ho\u1ea1t ch\u1ea5t tr\u1ecb n\u00e1m kh\u00e1c v\u1edbi m\u1ee5c ti\u00eau n\u00e2ng cao hi\u1ec7u qu\u1ea3 s\u00e1ng da, gi\u1ea3m h\u1eafc s\u1eafc t\u1ed1 v\u00e0 c\u00f3 th\u1ec3 h\u1ea1n ch\u1ebf t\u1ed1i \u0111a c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n.<\/p>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c tr\u1ecb n\u00e1m \u0111ang \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u<\/figcaption><\/figure>\n
N-acetyl-4-S-cysteaminyl phenol<\/h4>\n
NCAP l\u00e0 m\u1ed9t ch\u1ea5t phenolic ho\u1ea1t \u0111\u1ed9ng nh\u01b0 m\u1ed9t ch\u1ea5t n\u1ec1n thay th\u1ebf cho Tyrosinase, do \u0111\u00f3 \u1ee9c ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a enzyme. N\u00f3 \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o l\u00e0 \u1ed5n \u0111\u1ecbnh h\u01a1n v\u00e0 \u00edt g\u00e2y k\u00edch \u1ee9ng h\u01a1n Hydroquinone. C\u00e1c nghi\u00ean c\u1ee9u ch\u1ec9 ra r\u1eb1ng b\u00f4i NCAP 4% b\u00f4i ngo\u00e0i da h\u00e0ng ng\u00e0y, ng\u01b0\u1eddi d\u00f9ng c\u00f3 th\u1ec3 nh\u1eadn th\u1ea5y nh\u1eefng thay \u0111\u1ed5i l\u00e2m s\u00e0ng th\u1ea5y r\u00f5 sau 2-4 tu\u1ea7n.<\/p>\n
Alpha-tocopheryl<\/h4>\n
H\u1ee3p ch\u1ea5t c\u1ee7a alpha-tocopherol v\u00e0 Acid ferulic, c\u0169ng l\u00e0 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a \u0111\u01b0\u1ee3c k\u1ebft n\u1ed1i b\u1eb1ng li\u00ean k\u1ebft este, alpha-tocopheryl ferulate (alpha-TF), c\u00f3 th\u1ec3 h\u1ea5p th\u1ee5 b\u1ee9c x\u1ea1 tia c\u1ef1c t\u00edm (UV) v\u00e0 do \u0111\u00f3 duy tr\u00ec tocopherol \u1edf tr\u1ea1ng th\u00e1i \u1ed5n \u0111\u1ecbnh. Trong c\u00e1c nghi\u00ean c\u1ee9u th\u1ef1c nghi\u1ec7m, t\u00e1c nh\u00e2n n\u00e0y \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n c\u00f3 t\u00e1c d\u1ee5ng \u0111\u00e1ng k\u1ec3 trong vi\u1ec7c l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh h\u00ecnh th\u00e0nh h\u1eafc t\u1ed1, c\u00f3 th\u1ec3 b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf ho\u1ea1t \u0111\u1ed9ng tyrosine hydroxylase m\u1ed9t c\u00e1ch gi\u00e1n ti\u1ebfp.<\/p>\n
Acid Ascorbic<\/h4>\n
Acid Ascorbic c\u00f3 \u0111\u1eb7c t\u00ednh ch\u1ed1ng oxy h\u00f3a v\u00e0 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh h\u00ecnh th\u00e0nh melanogen b\u1eb1ng c\u00e1ch kh\u1eed dopaquinone th\u00e0nh DOPA v\u00e0 ng\u0103n ng\u1eeba s\u1ef1 s\u1ea3n sinh g\u1ed1c t\u1ef1 do v\u00e0 h\u1ea5p th\u1ee5 b\u1ee9c x\u1ea1 c\u1ef1c t\u00edm. Acid Ascorbic \u0111\u00f3ng m\u1ed9t vai tr\u00f2 trong \u0111i\u1ec1u tr\u1ecb n\u00e1m v\u00ec n\u00f3 g\u1ea7n nh\u01b0 kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u01a1n l\u1ebb ho\u1eb7c k\u1ebft h\u1ee3p. Acid L-ascorbic 25% \u0111\u01b0\u1ee3c pha ch\u1ebf v\u1edbi ch\u1ea5t t\u0103ng c\u01b0\u1eddng th\u1ea9m th\u1ea5u, \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n l\u00e0 c\u00f3 t\u00e1c d\u1ee5ng \u0111\u00e1ng k\u1ec3 trong \u0111i\u1ec1u tr\u1ecb n\u00e1m. Tuy nhi\u00ean , Acid Ascorbic r\u1ea5t kh\u00f4ng \u1ed5n \u0111\u1ecbnh trong dung d\u1ecbch n\u01b0\u1edbc v\u00e0 c\u00e1c este \u1ed5n \u0111\u1ecbnh nh\u01b0 magie ascorbyl- 2-phosphate (MAP) \u0111\u00e3 \u0111\u01b0\u1ee3c t\u1ed5ng h\u1ee3p. MAP c\u00f3 t\u00e1c d\u1ee5ng b\u1ea3o v\u1ec7 ch\u1ed1ng l\u1ea1i b\u1ee9c x\u1ea1 UVB v\u00e0 n\u00f3 \u1ee9c ch\u1ebf s\u1ef1 h\u00ecnh th\u00e0nh h\u1eafc t\u1ed1 trong \u1ed1ng nghi\u1ec7m v\u00e0 in vivo .<\/p>\n
Niacinamide<\/h4>\n
Niacinamide (nicotinamide), d\u1ea1ng amid c\u00f3 ho\u1ea1t t\u00ednh sinh h\u1ecdc c\u1ee7a Niacin (vitamin B3 ), c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m s\u1eafc t\u1ed1 b\u1eb1ng c\u00e1ch ng\u0103n ch\u1eb7n c\u00f3 th\u1ec3 \u0111\u1ea3o ng\u01b0\u1ee3c s\u1ef1 chuy\u1ec3n Melanosome t\u1eeb t\u1ebf b\u00e0o h\u1eafc t\u1ed1 sang t\u1ebf b\u00e0o s\u1eebng. N\u00f3 kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ed1i v\u1edbi ho\u1ea1t \u0111\u1ed9ng c\u1ee7a Tyrosinase. Trong c\u00e1c nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng, niacinamide l\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 t\u00ecnh tr\u1ea1ng t\u0103ng s\u1eafc t\u1ed1 v\u00e0 t\u0103ng \u0111\u1ed9 s\u00e1ng c\u1ee7a da so v\u1edbi ch\u1ec9 d\u00f9ng t\u00e1 d\u01b0\u1ee3c sau b\u1ed1n tu\u1ea7n s\u1eed d\u1ee5ng.<\/p>\n
D\u1eabn xu\u1ea5t cam th\u1ea3o<\/h4>\n
Cam th\u1ea3o l\u00e0 r\u1ec5 c\u1ee7a lo\u1ea1i th\u1ea3o d\u01b0\u1ee3c l\u00e2u n\u0103m Glycyrrhiza glabra. Glabridin l\u00e0 m\u1ed9t d\u1eabn xu\u1ea5t h\u00f2a tan trong d\u1ea7u c\u1ee7a chi\u1ebft xu\u1ea5t cam th\u1ea3o. Glabridin \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 c\u00f3 \u0111\u1eb7c t\u00ednh \u1ee9c ch\u1ebf Tyrosinase c\u0169ng nh\u01b0 ch\u1ed1ng vi\u00eam trong c\u00e1c nghi\u00ean c\u1ee9u th\u1ef1c nghi\u1ec7m. M\u1ed9t th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng v\u1edbi Liquiritin , m\u1ed9t d\u1eabn xu\u1ea5t cam th\u1ea3o kh\u00e1c, c\u0169ng cho th\u1ea5y l\u1ee3i \u00edch trong \u0111i\u1ec1u tr\u1ecb n\u00e1m.<\/p>\n
Flavonoid<\/h4>\n
Flavonoid l\u00e0 c\u00e1c h\u1ee3p ch\u1ea5t polyphenolic t\u1ef1 nhi\u00ean c\u00f3 \u0111\u1eb7c t\u00ednh ch\u1ed1ng vi\u00eam, ch\u1ed1ng oxy h\u00f3a, kh\u00e1ng vi-r\u00fat v\u00e0 ch\u1ed1ng ung th\u01b0 n\u1ed5i ti\u1ebfng. Nhi\u1ec1u h\u1ee3p ch\u1ea5t flavonoid c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb th\u1ef1c v\u1eadt c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m s\u1eafc t\u1ed1 v\u00e0 vai tr\u00f2 c\u1ee7a ch\u00fang v\u1eabn \u0111ang \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u. Ch\u00fang bao g\u1ed3m catechin li\u00ean h\u1ee3p v\u1edbi Acid gallic (t\u1eeb l\u00e1 tr\u00e0 xanh), Acid ellagic (t\u1eeb tr\u00e0 xanh, d\u00e2u t\u00e2y, b\u1ea1ch \u0111\u00e0n, v.v.) v\u00e0 aloesin (t\u1eeb c\u00e2y l\u00f4 h\u1ed9i).<\/p>\n
T\u01b0 v\u1ea5n c\u1ee7a d\u01b0\u1ee3c s\u0129 trong \u0111i\u1ec1u tr\u1ecb n\u00e1m<\/h2>\n
C\u00f3 c\u1ea7n b\u00f4i kem ch\u1ed1ng n\u1eafng trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb n\u00e1m kh\u00f4ng?<\/h3>\n
Tia c\u1ef1c t\u00edm (tia UV) c\u00f3 trong \u00e1nh n\u1eafng m\u1eb7t tr\u1eddi ch\u00ednh l\u00e0 m\u1ed9t trong nh\u1eefng y\u1ebfu t\u1ed1 h\u00e0ng \u0111\u1ea7u k\u00edch th\u00edch t\u0103ng sinh h\u1eafc s\u1eafc t\u1ed1, \u0111\u1ec3 t\u1eeb \u0111\u00f3 d\u1eabn t\u1edbi n\u00e1m da. V\u00ec v\u1eady b\u00f4i kem ch\u1ed1ng n\u1eafng l\u00e0 m\u1ed9t b\u01b0\u1edbc b\u1ea3o v\u1ec7 da kh\u1ecfi l\u00e3o h\u00f3a v\u00e0 c\u00e1c t\u00ecnh tr\u1ea1ng b\u1ec7nh li\u00ean quan \u0111\u1ebf h\u1eafc s\u1eafc t\u1ed1 nh\u01b0 n\u00e1m, t\u00e0n nhang,..<\/p>\n
B\u00ean c\u1ea1nh \u0111\u00f3, c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb n\u00e1m ngo\u00e0i t\u00e1c d\u1ee5ng l\u00e0m s\u00e1ng da, gi\u1ea3m t\u0103ng sinh h\u1eafc s\u1eafc t\u1ed1, m\u1ed9t s\u1ed1 lo\u1ea1i c\u00f2n c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m bong l\u1edbp bi\u1ec3u b\u00ec b\u00ean ngo\u00e0i \u0111\u1ec3 \u0111\u1ea9y nhanh qu\u00e1 tr\u00ecnh c\u1ea3i thi\u1ec7n l\u00e0n da. Trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb n\u00e1m, da c\u1ee7a ng\u01b0\u1eddi d\u00f9ng thu\u1ed1c s\u1ebd v\u00f4 c\u00f9ng nh\u1ea1y c\u1ea3m v\u00ec v\u1eady c\u00e0ng n\u00ean s\u1eed d\u1ee5ng c\u00e1c lo\u1ea1i kem ch\u1ed1ng n\u1eafng \u0111\u1ec3 b\u1ea3o v\u1ec7 l\u00e0n da, tr\u00e1nh tr\u01b0\u1eddng h\u1ee3p t\u00e1i l\u1ea1i.
\nNg\u01b0\u1eddi d\u00f9ng khi l\u1ef1a ch\u1ecdn kem ch\u1ed1ng n\u1eafng c\u1ea7n h\u1ebft s\u1ee9c l\u01b0u \u00fd v\u1ec1 ch\u1ec9 s\u1ed1 SPF c\u0169ng nh\u01b0 ph\u1ed5 ch\u1ed1ng n\u1eafng c\u1ee7a lo\u1ea1i kem m\u00ecnh d\u00f9ng. Ch\u1ec9 s\u1ed1 SPF kho\u1ea3ng 30 – 50 l\u00e0 ph\u00f9 h\u1ee3p, SPF qu\u00e1 cao c\u0169ng c\u00f3 th\u1ec3 g\u00e2y \u1ea3nh h\u01b0\u1edfng t\u1edbi da. N\u00ean ch\u1ecdn lo\u1ea1i kem ch\u1ed1ng n\u1eafng c\u00f3 ph\u1ed5 c\u00e0ng r\u1ed9ng c\u00e0ng t\u1ed1t.<\/p>\n
\u0110i\u1ec1u tr\u1ecb n\u00e1m sau bao l\u00e2u l\u00e0 kh\u1ecfi?<\/h3>\n
Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb n\u00e1m s\u1ebd ph\u1ee5 thu\u1ed9c v\u00e0o t\u00ecnh tr\u1ea1ng da c\u1ee7a t\u1eebng ng\u01b0\u1eddi v\u00e0 ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec7u tr\u00ecnh \u0111i\u1ec1u tr\u1ecb. Nhi\u1ec1u ng\u01b0\u1eddi \u0111\u1eb7t ra c\u00e2u h\u1ecfi d\u00f9ng kem tr\u1ecb n\u00e1m bao l\u00e2u th\u00ec c\u00f3 t\u00e1c d\u1ee5ng<\/strong>? M\u1ed7i lo\u1ea1i thu\u1ed1c, li\u1ec7u tr\u00ecnh \u0111i\u1ec1u tr\u1ecb s\u1ebd c\u1ea7n th\u1eddi gian t\u00e1c d\u1ee5ng kh\u00e1c nhau. V\u00ed d\u1ee5 nh\u01b0 th\u1eddi gian \u0111i\u1ec1u tr\u1ecb v\u1edbi Hydroquinone s\u1ebd kho\u1ea3ng 5 – 7 tu\u1ea7n, v\u1edbi Acid Tranexamic c\u1ea7n 8 -12 tu\u1ea7n v\u00e0 v\u1edbi Retinoid c\u1ea7n th\u1eddi gian t\u1edbi 24 tu\u1ea7n. M\u1ed9t \u0111i\u1ec1u l\u01b0u \u00fd khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb n\u00e1m l\u00e0 ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n ph\u1ea3i ki\u00ean tr\u00ec v\u00e0 tu\u00e2n th\u1ee7 theo li\u1ec7u tr\u00ecnh. K\u1ec3 c\u1ea3 sau khi li\u1ec7u tr\u00ecnh k\u1ebft th\u00fac, l\u00e0n da c\u0169ng c\u1ea7n th\u1eddi gian v\u00e0i th\u00e1ng \u0111\u1ec3 ph\u1ee5c h\u1ed3i l\u1ea1i kh\u1ecfe m\u1ea1nh ho\u00e0n to\u00e0n.<\/p>\n
C\u00f3 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e1m kh\u1ecfi v\u0129nh vi\u1ec5n kh\u00f4ng?<\/h3>\n
C\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb hi\u1ec7n t\u1ea1i, k\u1ec3 c\u1ea3 d\u00f9ng thu\u1ed1c hay s\u1eed d\u1ee5ng c\u00f4ng ngh\u1ec7 can thi\u1ec7p nh\u01b0 laser hay l\u0103n kim vi \u0111i\u1ec3m \u0111\u1ec1u l\u00e0 nh\u1eefng ph\u01b0\u01a1ng ph\u00e1p hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb n\u00e1m. Tuy nhi\u00ean, sau khi \u0111i\u1ec1u tr\u1ecb n\u1ebfu ng\u01b0\u1eddi b\u1ec7nh kh\u00f4ng ch\u0103m s\u00f3c l\u00e0n da t\u1ed1t, kh\u00f4ng ki\u1ec3m so\u00e1t nh\u1eefng y\u1ebfu t\u1ed1 g\u00e2y n\u00e1m nh\u01b0 stress, n\u1ed9i ti\u1ebft,… th\u00ec ho\u00e0n to\u00e0n c\u00f3 th\u1ec3 m\u1eafc n\u00e1m tr\u1edf l\u1ea1i. B\u1ea1n \u0111\u1ecdc c\u1ea7n h\u1ebft s\u1ee9c t\u1ec9nh t\u00e1o v\u1edbi c\u00e1c l\u1eddi qu\u1ea3ng c\u00e1o th\u1ed5i ph\u1ed3ng v\u1ec1 vi\u1ec7c \u201cch\u1eefa h\u1ebft n\u00e1m da v\u0129nh vi\u1ec5n\u201d c\u1ee7a c\u00e1c th\u1ea9m m\u1ef9 vi\u1ec7n, trang web kh\u00f4ng uy t\u00edn. \u0110i\u1ec1u tr\u1ecb n\u00e1m l\u00e0 m\u1ed9t qu\u00e1 tr\u00ecnh \u0111\u00f2i h\u1ecfi s\u1ef1 ki\u00ean tr\u00ec v\u00e0 tu\u00e2n th\u1ee7 c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh, ng\u01b0\u1eddi b\u1ec7nh kh\u00f4ng n\u00ean n\u00f3ng l\u00f2ng v\u1ed9i tin v\u00e0o nh\u1eefng qu\u1ea3ng c\u00e1o hoa m\u1ef9 kh\u00f4ng c\u00f3 t\u00ednh ch\u00ednh x\u00e1c.<\/p>\n
C\u00f3 b\u1ea7u c\u00f3 \u0111\u01b0\u1ee3c d\u00f9ng kem tr\u1ecb n\u00e1m kh\u00f4ng?<\/h3>\n
Trong th\u1eddi k\u1ef3 mang thai, do thay \u0111\u1ed5i n\u1ed9i ti\u1ebft t\u1ed1 khi\u1ebfn cho ng\u01b0\u1eddi m\u1eb9 xu\u1ea5t hi\u1ec7n c\u00e1c v\u1ebft n\u00e1m ho\u1eb7c k\u00edch th\u00edch t\u0103ng h\u1eafc s\u1eafc t\u1ed1 khi\u1ebfn n\u00e1m kh\u00f3 \u0111i\u1ec1u tr\u1ecb h\u01a1n. Th\u00f4ng th\u01b0\u1eddng vi\u1ec7c \u0111i\u1ec1u tr\u1ecb n\u00e1m s\u1ebd \u0111\u01b0\u1ee3c tr\u00ec ho\u00e3n cho \u0111\u1ebfn sau khi sinh. B\u00ean c\u1ea1nh \u0111\u00f3, vi\u1ec7c \u0111i\u1ec1u tr\u1ecb c\u00f3 th\u1ec3 kh\u00f4ng c\u1ea7n thi\u1ebft v\u00ec n\u00e1m khi mang thai c\u00f3 th\u1ec3 ch\u1ec9 x\u1ea3y ra tho\u00e1ng qua, lo\u1ea1i b\u1ecf t\u00e1c nh\u00e2n k\u00edch th\u00edch n\u1ed9i ti\u1ebft t\u1ed1 sau khi sinh con c\u00f3 th\u1ec3 mang l\u1ea1i s\u1ef1 c\u1ea3i thi\u1ec7n \u0111\u00e1ng k\u1ec3 tr\u00ean da.<\/p>\n
N\u1ebfu ng\u01b0\u1eddi m\u1eb9 v\u1eabn mu\u1ed1n \u0111i\u1ec1u tr\u1ecb n\u00e1m trong th\u1eddi gian mang thai th\u00ec c\u1ea7n c\u00f3 s\u1ef1 t\u01b0 v\u1ea5n, ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129, kh\u00f4ng t\u1ef1 \u00fd s\u1eed d\u1ee5ng c\u00e1c lo\u1ea1i kem b\u00f4i tr\u1ecb n\u00e1m v\u00ec m\u1ed9t s\u1ed1 th\u00e0nh ph\u1ea7n ho\u1ea1t ch\u1ea5t \u0111i\u1ec1u tr\u1ecb n\u00e1m c\u00f3 th\u1ec3 g\u00e2y \u0111\u1ed9c cho thai nhi nh\u01b0:<\/p>\n
\n
Retinol v\u00e0 c\u00e1c d\u1eabn xu\u1ea5t c\u1ee7a vitamin A<\/li>\n
BHA\/Acid salicylic<\/li>\n
Hydroquinone<\/li>\n<\/ul>\n
B\u00ean c\u1ea1nh nh\u1eefng ho\u1ea1t ch\u1ea5t c\u1ea7n tr\u00e1nh \u0111\u00e3 n\u00eau tr\u00ean, d\u01b0\u1edbi \u0111\u00e2y l\u00e0 m\u1ed9t s\u1ed1 ho\u1ea1t ch\u1ea5t tr\u1ecb n\u00e1m an to\u00e0n h\u01a1n, c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng trong th\u1eddi k\u1ef3 mang thai:<\/p>\n
\n
Kojic Acid: L\u00e0 th\u00e0nh ph\u1ea7n c\u00f3 \u0111\u01b0\u1ee3c trong qu\u00e1 tr\u00ecnh l\u00ean men m\u1ea1ch nha trong s\u1ea3n xu\u1ea5t r\u01b0\u1ee3u sake cho t\u00e1c d\u1ee5ng l\u00e0m \u0111\u1ec1u m\u00e0u da v\u00e0 \u1ee9c ch\u1ebf melanin hi\u1ec7u qu\u1ea3.<\/li>\n
Alpha Hydroxy Acid (AHAs) g\u1ed3m c\u00e1c lo\u1ea1i axit nh\u01b0 Glycolic acid, Citric acid, Mandelic acid, Lactic acid. \u0110\u00e2y \u0111\u1ec1u l\u00e0 nh\u1eefng lo\u1ea1i AHA kh\u00e1 l\u00e0nh t\u00ednh nh\u01b0ng cho kh\u1ea3 n\u0103ng t\u1ea9y t\u1ebf b\u00e0o ch\u1ebft tr\u00ean da hi\u1ec7u qu\u1ea3.<\/li>\n
Axit azelaic: \u0110\u00e2y l\u00e0 m\u1ed9t ho\u1ea1t ch\u1ea5t trong nh\u00f3m axit dicarboxylic c\u00f3 th\u1ec3 t\u00ecm th\u1ea5y trong l\u00faa m\u00ec, l\u00faa m\u1ea1ch cho kh\u1ea3 n\u0103ng tr\u1ecb m\u1ee5n v\u00e0 \u1ee9c ch\u1ebf melanin an to\u00e0n, hi\u1ec7u qu\u1ea3.<\/li>\n
Vitamin C: L\u00e0 ho\u1ea1t ch\u1ea5t th\u01b0\u1eddng \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong c\u00e1c lo\u1ea1i tr\u00e1i c\u00e2y nh\u01b0 \u1ed5i, cam, chanh. Th\u00e0nh ph\u1ea7n n\u00e0y c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m s\u00e1ng da nh\u1edd t\u0103ng sinh collagen, t\u0103ng m\u1ee9c \u0111\u1ed9 li\u00ean k\u1ebft gi\u1eefa c\u00e1c m\u00f4 v\u00e0 \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh h\u00ecnh th\u00e0nh melanin.h\u00f3a
\nNh\u00ecn chung, th\u1eddi \u0111i\u1ec3m mang thai l\u00e0 th\u1eddi \u0111i\u1ec3m nh\u1ea1y c\u1ea3m, ng\u01b0\u1eddi m\u1eb9 n\u00ean c\u1ea9n th\u1eadn v\u1edbi b\u1ea5t k\u1ef3 s\u1ea3n ph\u1ea9m \u0111i\u1ec1u tr\u1ecb n\u00e0o s\u1eed d\u1ee5ng trong th\u1eddi k\u1ef3 n\u00e0y. Ng\u01b0\u1eddi m\u1eb9 c\u1ea7n \u0111\u1ebfn g\u1eb7p b\u00e1c s\u0129 \u0111\u1ec3 c\u00f3 \u0111\u01b0\u1ee3c li\u1ec7u tr\u00ecnh, ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3.<\/li>\n<\/ul>\n
$\"Thu\u1ed1c$ <\/a>
Thu\u1ed1c tr\u1ecb n\u00e1m d\u00f9ng cho b\u00e0 b\u1ea7u<\/figcaption><\/figure>\n
Ph\u1ee5 n\u1eef cho con b\u00fa c\u00f3 n\u00ean d\u00f9ng thu\u1ed1c tr\u1ecb n\u00e1m?<\/h3>\n
Ph\u1ee5 n\u1eef cho con b\u00fa c\u0169ng l\u00e0 m\u1ed9t \u0111\u1ed1i t\u01b0\u1ee3ng \u0111\u1eb7c bi\u1ec7t c\u1ea7n l\u01b0u \u00fd khi s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb n\u00e1m. Trong 6 th\u00e1ng \u0111\u1ea7u c\u1ee7a tr\u1ebb, tr\u1ebb nh\u1eadn dinh d\u01b0\u1ee1ng ho\u00e0n to\u00e0n t\u1eeb s\u1eefa m\u1eb9, v\u00ec v\u1eady, nh\u1eefng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb n\u00e1m b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 l\u00e0 m\u1ed9t m\u1ed1i nguy c\u01a1 l\u1edbn \u0111\u1ed1i v\u1edbi tr\u1ebb.<\/p>\n
C\u00e1c chuy\u00ean gia da li\u1ec5u khuy\u00ean m\u1eb9 kh\u00f4ng n\u00ean d\u00f9ng c\u00e1c thu\u1ed1c \u0111\u1eb7c tr\u1ecb n\u00e1m trong th\u1eddi gian cho con b\u00fa. N\u1ebfu ng\u01b0\u1eddi m\u1eb9 v\u1eabn mu\u1ed1n s\u1eed d\u1ee5ng thu\u1ed1c tr\u1ecb n\u00e1m th\u00ec c\u1ea7n tham kh\u1ea3o \u00fd ki\u1ebfn b\u00e1c s\u0129 v\u00e0 s\u1eed d\u1ee5ng c\u00e1c lo\u1ea1i kem b\u00f4i an to\u00e0n l\u00e0nh t\u00ednh. Thay v\u00ec c\u00e1c bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u00e1m b\u1eb1ng thu\u1ed1c \u0111\u1eb7c tr\u1ecb, c\u00e1c m\u1eb9 c\u00f3 th\u1ec3 tham kh\u1ea3o m\u1ed9t s\u1ed1 bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba n\u00e1m nh\u01b0:<\/p>\n
\n
H\u1ea1n ch\u1ebf ti\u1ebfp x\u00fac v\u1edbi \u00e1nh n\u1eafng m\u1eb7t tr\u1eddi v\u00e0o th\u1eddi \u0111i\u1ec3m UV cao (t\u1eeb 9h s\u00e1ng \u0111\u1ebfn 15h chi\u1ec1u).<\/li>\n
B\u1ed5 sung ngu\u1ed3n dinh d\u01b0\u1ee1ng c\u00e1c ch\u1ea5t ch\u1ed1ng oxy h\u00f3a t\u1eeb thi\u00ean nhi\u00ean.<\/li>\n
S\u1eed d\u1ee5ng m\u1ef9 ph\u1ea9m b\u1ea3o v\u1ec7 da, kem ch\u1ed1ng n\u1eafng lo\u1ea1i an to\u00e0n, l\u00e0nh t\u00ednh.<\/li>\n
H\u1ea1n ch\u1ebf t\u1ed1i \u0111a nh\u1eefng y\u1ebfu t\u1ed1 g\u00e2y stress.<\/li>\n<\/ul>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n
\n
T\u00e1c gi\u1ea3 Debabrata Bandyopadhyay (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 10 – 12 n\u0103m 2009). TOPICAL TREATMENT OF MELASMA<\/em>, PMC. Th\u1eddi gian truy c\u1eadp ng\u00e0y 1 th\u00e1ng 11 n\u0103m 2023, t\u1eeb https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2807702\/<\/a><\/li>\n
T\u00e1c gi\u1ea3 Marta Rendon MD a, Mark Berneburg MD b, Ivonne Arellano MD c, Mauro Picardo MD (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 5 n\u0103m 2006). Treatment of melasma<\/em>, Journal of the American Academy of Dermatology. Th\u1eddi gian truy c\u1eadp ng\u00e0y 1 th\u00e1ng 11 n\u0103m 2023, t\u1eeb https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0190962205049662<\/a><\/li>\n
T\u00e1c gi\u1ea3 Harini R Bala, Senhong Lee, Celestine Wong, Amit G Pandya, Michelle Rodrigues (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 6 n\u0103m 2018). Oral Tranexamic Acid for the Treatment of Melasma: A Review<\/em>, Pubmed. Th\u1eddi gian truy c\u1eadp ng\u00e0y 1 th\u00e1ng 11 n\u0103m 2023, t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/29677015\/<\/a><\/li>\n
T\u00e1c gi\u1ea3 Yong Chool Boo (Th\u1eddi gian ph\u00e1t h\u00e0nh ng\u00e0y 15 th\u00e1ng 7 n\u0103m 2021). Arbutin as a Skin Depigmenting Agent with Antimelanogenic and Antioxidant Properties<\/em>, Pubmed. Th\u1eddi gian truy c\u1eadp ng\u00e0y 1 th\u00e1ng 11 n\u0103m 2023, t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/34356362\/<\/a><\/li>\n
T\u00e1c gi\u1ea3 Tamara Searle, Firas Al-Niaimi, Faisal R Ali (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 11 n\u0103m 2020). The top 10 cosmeceuticals for facial hyperpigmentation<\/em>, Pubmed. Th\u1eddi gian truy c\u1eadp ng\u00e0y 1 th\u00e1ng 11 n\u0103m 2023, t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/32720446\/<\/a><\/li>\n
T\u00e1c gi\u1ea3 Michael Jarratt (Th\u1eddi gian ph\u00e1t h\u00e0nh th\u00e1ng 11 n\u0103m 2004). Mequinol 2%\/tretinoin 0.01% solution: an effective and safe alternative to hydroquinone 3% in the treatment of solar lentigines<\/em>, Pubmed. Truy c\u1eadp ng\u00e0y 1 th\u00e1ng 11 n\u0103m 2023, t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/15605971\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"
N\u00e1m da v\u00e0 c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 n\u00e1m lu\u00f4n l\u00e0 ch\u1ee7 \u0111\u1ec1 nh\u1eadn \u0111\u01b0\u1ee3c s\u1ef1 quan t\u00e2m c\u1ee7a nh\u1eefng ng\u01b0\u1eddi y\u00eau th\u00edch c\u00e1i \u0111\u1eb9p, c\u00f3 mong mu\u1ed1n s\u1edf h\u1eefu l\u00e0n da \u0111\u1eb9p. B\u00e0i vi\u1ebft n\u00e0y s\u1ebd \u0111\u1ec1 c\u1eadp t\u1edbi c\u00e1c lo\u1ea1i thu\u1ed1c tr\u1ecb n\u00e1m hi\u1ec7u qu\u1ea3 v\u00e0 th\u00f4ng d\u1ee5ng tr\u00ean th\u1ecb tr\u01b0\u1eddng. T\u00ecm hi\u1ec3u v\u1ec1 […]\n","protected":false},"author":1,"featured_media":54350,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-54347","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/54347","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=54347"}],"version-history":[{"count":1,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/54347\/revisions"}],"predecessor-version":[{"id":72465,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/54347\/revisions\/72465"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/54350"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=54347"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=54347"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=54347"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}