{"id":5047,"date":"2019-03-19T10:45:08","date_gmt":"2019-03-19T03:45:08","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?p=5047"},"modified":"2019-03-19T11:09:21","modified_gmt":"2019-03-19T04:09:21","slug":"bang-chung-moi-ve-moi-lien-quan-giua-aspirin-lieu-thap-va-giam-nguy-co-ung-thu-phoi","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/bang-chung-moi-ve-moi-lien-quan-giua-aspirin-lieu-thap-va-giam-nguy-co-ung-thu-phoi\/","title":{"rendered":"B\u1eb1ng ch\u1ee9ng m\u1edbi v\u1ec1 m\u1ed1i li\u00ean quan gi\u1eefa aspirin li\u1ec1u th\u1ea5p v\u00e0 gi\u1ea3m nguy c\u01a1 ung th\u01b0 ph\u1ed5i"},"content":{"rendered":"<p>S\u1eed d\u1ee5ng aspirin li\u1ec1u th\u1ea5p t\u1eeb 5 \u0111\u1ebfn 9 n\u0103m c\u00f3 li\u00ean quan \u0111\u1ebfn gi\u1ea3m nguy c\u01a1 t\u01b0\u01a1ng \u0111\u1ed1i m\u1eafc ung th\u01b0 ph\u1ed5i.<\/p>\n<p>T\u1ed5ng h\u1ee3p: Ng\u00f4 Nguy\u00ean Nh\u1eadt Anh, Sinh vi\u00ean D15 \u0110\u1ea1i h\u1ecdc Y D\u01b0\u1ee3c TP HCM<\/p>\n<p>Hi\u1ec7u \u0111\u00ednh: D\u01b0\u1ee3c s\u0129 Tr\u01b0\u01a1ng C\u00f4ng B\u1eb1ng.<\/p>\n<h2>T\u1ed5ng quan<\/h2>\n<p>T\u00e1c \u0111\u1ed9ng \u1ee9c ch\u1ebf cyclooxygenase c\u1ee7a aspirin \u0111\u01b0\u1ee3c cho l\u00e0 nguy\u00ean nh\u00e2n l\u00e0m gi\u1ea3m nguy c\u01a1 ung th\u01b0 ph\u1ed5i. M\u1ed9t s\u1ed1 th\u1eed nghi\u1ec7m ng\u1eabu nhi\u00ean \u0111\u00e3 cho th\u1ea5y vi\u1ec7c s\u1eed d\u1ee5ng aspirin li\u1ec1u th\u1ea5p k\u00e9o d\u00e0i mang l\u1ea1i l\u1ee3i \u00edch cho b\u1ec7nh nh\u00e2n nh\u01b0ng c\u00e1c nghi\u00ean c\u1ee9u d\u1ecbch t\u1ec5 h\u1ecdc v\u00e0 \u0111o\u00e0n h\u1ec7 (\u0111\u1eb7c bi\u1ec7t \u1edf ph\u1ee5 n\u1eef) cho th\u1ea5y kh\u00f4ng c\u00f3 l\u1ee3i \u00edch.<\/p>\n<h2>Thi\u1ebft k\u1ebf nghi\u00ean c\u1ee9u<\/h2>\n<p>Trong nghi\u00ean c\u1ee9u n\u00e0y, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u H\u00e0n Qu\u1ed1c \u0111\u00e3 s\u1eed d\u1ee5ng c\u01a1 s\u1edf d\u1eef li\u1ec7u qu\u1ed1c gia v\u1edbi g\u1ea7n 13.000.000 b\u1ec7nh nh\u00e2n c\u00f3 th\u00f4ng tin v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng aspirin v\u00e0 ch\u1ea9n \u0111o\u00e1n ung th\u01b0 ph\u1ed5i<\/p>\n<p>S\u1eed d\u1ee5ng aspirin li\u1ec1u th\u1ea5p \u0111\u01b0\u1ee3c \u0111\u1ecbnh ngh\u0129a l\u00e0 s\u1eed d\u1ee5ng aspirin v\u1edbi li\u1ec1u \u2264100 mg\/ng\u00e0y, \u00edt nh\u1ea5t 2 ng\u00e0y\/tu\u1ea7n.<br \/>\nNh\u1eefng b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n ung th\u01b0 ph\u1ed5i tr\u01b0\u1edbc \u0111\u00f3 v\u00e0\/ho\u1eb7c s\u1eed d\u1ee5ng aspirin li\u1ec1u ti\u00eau chu\u1ea9n (\u2265325 mg) tr\u01b0\u1edbc \u0111\u00f3 b\u1ecb lo\u1ea1i kh\u1ecfi nghi\u00ean c\u1ee9u.<\/p>\n<h2>K\u1ebft qu\u1ea3<\/h2>\n<p>C\u00e1c bi\u1ebfn nh\u00e2n kh\u1ea9u h\u1ecdc v\u00e0 c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 tr\u00ean l\u00e2m s\u00e0ng \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh.<br \/>\nTrong th\u1eddi gian theo d\u00f5i 5 n\u0103m, kho\u1ea3ng 63.000 tr\u01b0\u1eddng h\u1ee3p ung th\u01b0 ph\u1ed5i \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n.<br \/>\nB\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng aspirin li\u1ec1u th\u1ea5p k\u00e9o d\u00e0i c\u00f3 nguy c\u01a1 m\u1eafc ung th\u01b0 ph\u1ed5i th\u1ea5p h\u01a1n \u0111\u00e1ng k\u1ec3 so v\u1edbi v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n kh\u00f4ng s\u1eed d\u1ee5ng aspirin (gi\u1ea3m l\u1ea7n l\u01b0\u1ee3t 4%, 6% v\u00e0 11% sau khi s\u1eed d\u1ee5ng aspirin trong 5-6 n\u0103m, 7-8 n\u0103m v\u00e0 9 n\u0103m).<br \/>\nTrong c\u00e1c ph\u00e2n t\u00edch d\u01b0\u1edbi nh\u00f3m, nh\u1eefng l\u1ee3i \u00edch t\u01b0\u01a1ng t\u1ef1 c\u0169ng \u0111\u01b0\u1ee3c ghi nh\u1eadn \u1edf b\u1ec7nh nh\u00e2n cao tu\u1ed5i (\u226565 tu\u1ed5i). \u1ede nh\u1eefng b\u1ec7nh nh\u00e2n &lt;65 tu\u1ed5i, \u0111\u1ed9 gi\u1ea3m nguy c\u01a1 t\u01b0\u01a1ng \u0111\u1ed1i nh\u1ecf v\u00e0 kh\u00f4ng c\u00f3 \u00fd ngh\u0129a th\u1ed1ng k\u00ea.<\/p>\n<h2>B\u00e0n lu\u1eadn<\/h2>\n<p>M\u1eb7c d\u00f9 nghi\u00ean c\u1ee9u quan s\u00e1t n\u00e0y c\u00f3 nhi\u1ec1u y\u1ebfu t\u1ed1 g\u00e2y nhi\u1ec5u, m\u1ed1i t\u01b0\u01a1ng quan gi\u1eefa vi\u1ec7c s\u1eed d\u1ee5ng aspirin li\u1ec1u th\u1ea5p k\u00e9o d\u00e0i v\u00e0 nguy c\u01a1 ung th\u01b0 ph\u1ed5i c\u1ee7ng c\u1ed1 th\u00eam c\u00e1c ph\u00e1t hi\u1ec7n trong nghi\u00ean c\u1ee9u tr\u01b0\u1edbc \u0111\u00e2y. Tuy nhi\u00ean, l\u1ee3i \u00edch th\u1ef1c s\u1ef1 kh\u00f4ng l\u1edbn v\u00e0 c\u1ea7n \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 to\u00e0n di\u1ec7n h\u01a1n.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Ye S, et al. Association of Long-term Use of Low-Dose Aspirin as Chemoprevention With Risk of Lung Cancer. JAMA Netw Open 2019 Mar 1; 2:e190185. Link\u00a0<a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2019.0185\" rel=\"noopener\">https:\/\/doi.org\/10.1001\/jamanetworkopen.2019.0185<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>S\u1eed d\u1ee5ng aspirin li\u1ec1u th\u1ea5p t\u1eeb 5 \u0111\u1ebfn 9 n\u0103m c\u00f3 li\u00ean quan \u0111\u1ebfn gi\u1ea3m nguy c\u01a1 t\u01b0\u01a1ng \u0111\u1ed1i m\u1eafc ung th\u01b0 ph\u1ed5i. T\u1ed5ng h\u1ee3p: Ng\u00f4 Nguy\u00ean Nh\u1eadt Anh, Sinh vi\u00ean D15 \u0110\u1ea1i h\u1ecdc Y D\u01b0\u1ee3c TP HCM Hi\u1ec7u \u0111\u00ednh: D\u01b0\u1ee3c s\u0129 Tr\u01b0\u01a1ng C\u00f4ng B\u1eb1ng. T\u1ed5ng quan T\u00e1c \u0111\u1ed9ng \u1ee9c ch\u1ebf cyclooxygenase c\u1ee7a aspirin \u0111\u01b0\u1ee3c [&#8230;]\n","protected":false},"author":1,"featured_media":5048,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-5047","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/5047","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=5047"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/5047\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/5048"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=5047"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=5047"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=5047"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}