{"id":4402,"date":"2019-03-13T14:08:15","date_gmt":"2019-03-13T07:08:15","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?p=4402"},"modified":"2019-03-13T14:08:15","modified_gmt":"2019-03-13T07:08:15","slug":"ve-benh-mat-ngu-man-tinh","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/ve-benh-mat-ngu-man-tinh\/","title":{"rendered":"V\u1ec1 b\u1ec7nh m\u1ea5t ng\u1ee7 m\u00e3n t\u00ednh"},"content":{"rendered":"

1. R\u1ed1i lo\u1ea1n m\u1ea5t ng\u1ee7<\/strong> \u0111\u01b0\u1ee3c \u0111\u1ecbnh ngh\u0129a l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n kh\u00f4ng do ho\u00e0n c\u1ea3nh hay c\u1ed1 \u00fd trong vi\u1ec7c kh\u1edfi \u0111\u1ea7u ho\u1eb7c duy tr\u00ec gi\u1ea5c ng\u1ee7 \u0111\u00eam m\u00e0 g\u00e2y ra nh\u1eefng \u1ea3nh h\u01b0\u1edfng n\u00e0o \u0111\u00f3 \u0111\u1ebfn t\u00ecnh tr\u1ea1ng th\u1ec3 ch\u1ea5t ng\u00e0y h\u00f4m sau. M\u1ea5t ng\u1ee7<\/strong> \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh l\u00e0 m\u00e3n t\u00ednh (Chronic Insomnia) khi n\u00f3 t\u1ed3n t\u1ea1i \u00edt nh\u1ea5t ba th\u00e1ng v\u1edbi t\u1ea7n su\u1ea5t \u00edt nh\u1ea5t ba l\u1ea7n m\u1ed7i tu\u1ea7n, ng\u01b0\u1ee3c l\u1ea1i, ch\u1ec9 l\u00e0 m\u1ea5t ng\u1ee7 t\u1ea1m th\u1eddi v\u00e0 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng nhi\u1ec1u \u0111\u1ebfn s\u1ee9c kh\u1ecfe t\u1ed5ng th\u1ec3, v\u00e0i th\u1ed1ng k\u00ea cho th\u1ea5y c\u00f3 t\u1ea7m 50% d\u00e2n s\u1ed1 c\u00f3 m\u1ea5t ng\u1ee7, trong \u0111\u00f3 c\u00f3 5-10% m\u1ea5t ng\u1ee7 m\u00e3n t\u00ednh.<\/p>\n

2. Tuy c\u00f3 nhi\u1ec1u ph\u00e1t hi\u1ec7n m\u1edbi v\u1ec1 c\u01a1 ch\u1ebf sinh h\u1ecdc c\u1ee7a chu k\u1ef3 Th\u1ee9c- Ng\u1ee7, c\u0103n nguy\u00ean c\u1ee7a m\u1ea5t ng\u0169 m\u00e3n t\u00ednh v\u1eabn c\u00f2n b\u00ed \u1ea9n, tin vui cho ng\u01b0\u1eddi m\u1ea5t ng\u1ee7 l\u00e0 h\u1ecd th\u01b0\u1eddng th\u00f4ng minh, nhi\u1ec1u n\u0103ng khi\u1ebfu, tin bu\u1ed3n l\u00e0 c\u00f3 m\u1ed1i li\u00ean quan t\u1eeb trung b\u00ecnh \u0111\u1ebfn cao gi\u1eefa m\u1ea5t ng\u1ee7 m\u00e3n t\u00ednh v\u1edbi c\u00e1c b\u1ec7nh l\u00fd t\u00e2m th\u1ea7n nh\u01b0 r\u1ed1i lo\u1ea1n lo \u00e2u, r\u1ed1i lo\u1ea1n c\u1ea3m x\u00fac, tr\u1ea7m c\u1ea3m, t\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t.<\/p>\n

3. C\u00e1c thu\u1ed1c an th\u1ea7n gi\u1ea3i lo h\u1ecd Benzodiazepines (BZD), thu\u1ed1c g\u00e2y ng\u0169 hypnotic non-BZD nh\u01b0 zolpidem, zolpidem gi\u1ea3i ph\u00f3ng ch\u1eadm, eszopiclone, zaleplon, v\u00e0 c\u00e1c thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m th\u01b0\u1eddng \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb m\u1ea5t ng\u1ee7 ngo\u00e0i tr\u1ecb li\u1ec7u \u0111i\u1ec1u ch\u1ec9nh h\u00e0nh vi, vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c cho m\u1ea5t ng\u1ee7 m\u00e3n t\u00ednh c\u00f3 nh\u1eefng quy \u0111\u1ecbnh ch\u1eb7t ch\u1ebb v\u1ec1 li\u1ec1u d\u00f9ng, th\u1eddi gian d\u00f9ng…nh\u1eb1m h\u1ea1n ch\u1ebf s\u1ef1 quen thu\u1ed1c hay l\u1ec7 thu\u1ed9c thu\u1ed1c, h\u1ea1n ch\u1ebf c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a thu\u1ed1c nh\u01b0 ng\u1ea7y ng\u1eadt ng\u00e0y h\u00f4m sau, d\u1ec3 g\u00e2y t\u00e9 ng\u00e3, gi\u1ea3m tr\u00ed nh\u1edb.<\/p>\n

4. M\u1eb7c d\u00f9 c\u00e1c thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m \u0111\u01b0\u1ee3c s\u1eed dung nhi\u1ec1u trong th\u1ef1c t\u1ebf \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb m\u1ea5t ng\u1ee7, b\u1eb1ng ch\u1ee9ng c\u1ee7a ch\u00fang v\u1eabn c\u00f2n thi\u1ebfu theo c\u00e1c \u0111\u00e1nh gi\u00e1 g\u1ea7n \u0111\u00e2y tr\u00ean th\u01b0 vi\u1ec7n y h\u1ecdc ch\u1ee9ng c\u1ee9 Cochrane. Ngo\u1ea1i tr\u1eeb Doxepin, c\u00e1c thu\u1ed1c SSRI hay TCA ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u x\u00e1c nh\u1eadn hi\u1ec7u qu\u1ea3 v\u00e0 t\u00ednh an to\u00e0n cho \u0111i\u1ec1u tr\u1ecb.<\/p>\n

5. H\u01b0\u1edbng d\u1eabn tr\u1ecb li\u1ec7u cho m\u1ea5t ng\u0169 m\u00e3n t\u00ednh c\u1ee7a AASM American Academy of Sleep Medicine 2017 bao g\u1ed3m c\u00e1c khuy\u1ebfn c\u00e1o sau<\/p>\n

– \u01afu ti\u00ean \u0111i\u1ec1u tr\u1ecb t\u00e2m l\u00fd v\u00e0 h\u00e0nh vi<\/p>\n

– \u0110i\u1ec1u tr\u1ecb thu\u1ed1c cho kh\u00f3 ng\u0169 \u0111\u1ea7u gi\u1ea5c : Eszopiclone, Zaleplon, Zolpidem, Triazolam, Temazepam, Ramelteon<\/p>\n

– \u0110i\u1ec1u tr\u1ecb thu\u1ed1c cho th\u1ee9c gi\u1ea5c n\u1eefa \u0111\u00eam v\u00e0 kh\u00f4ng ng\u0169 l\u1ea1i \u0111\u01b0\u1ee3c : Suvorexant, Eszopiclone, Zolpidem, Temazepam, Doxepin<\/p>\n

– C\u00e1c thu\u1ed1c kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng: Trazodone (ch\u1ed1ng tr\u1ea7m c\u1ea3m), Tiagabine (ch\u1ed1ng co gi\u1eadt) Diphenhydramine (kh\u00e1ng histamin), Melatonin (hormon tuy\u1ebfn t\u00f9ng t\u1ed5ng h\u1ee3p), Tryptophan (acid amin), Valerian (th\u1ea3o d\u01b0\u1ee3c)<\/p>\n

5. Ramelteon (Rozerem* Takeda) l\u00e0 m\u1ed9t ch\u1ea5t \u0111\u1ed3ng v\u1eadn th\u1ee5 th\u1ec3 melatonin (agonist MT1 v\u00e0 MT2). Melatonin l\u00e0 ch\u1ea5t \u0111i\u1ec1u h\u00f2a nh\u1ecbp sinh h\u1ecdc ng\u00e0y \u0111\u00eam hay l\u00e0 chu k\u1ef3 th\u1ee9c ng\u1ee7 circadian rhythme, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi tuy\u1ebfn t\u00f9ng \u1edf n\u00e3o v\u00e0 \u0111\u00e3 \u0111\u01b0\u1ee3c t\u1ed5ng h\u1ee3p, Rozerem \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn cho s\u1eed d\u1ee5ng th\u00e1ng 7\/2005<\/p>\n

5. Suvorexant (Belsomra* Merck) \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn th\u00e1ng 8\/2014, l\u00e0 m\u1ed9t \u0111\u1ed1i v\u1eadn ch\u1ecdn l\u1ecdc th\u1ee5 th\u1ebf orexin (dual orexin receptor antagonist, DORA, th\u1ee5 th\u1ec3 k\u1ebft h\u1ee3p G-protein, OX1R v\u00e0 OX2R), d\u1eabn \u0111\u1ebfn \u1ee9c ch\u1ebf t\u00e1c \u0111\u1ed9ng c\u1ee7a orexin, m\u1ed9t neuropeptide d\u1eabn truy\u1ec1n th\u1ea7n kinh c\u00f3 ch\u1ee9c n\u0103ng l\u00e0m t\u0103ng ho\u1ea1t h\u1ec7 giao c\u1ea3m, t\u0103ng v\u1eadn \u0111\u1ed9ng, t\u0103ng t\u1ec9nh th\u1ee9c, g\u00e2y th\u00e8m \u0103n hay kho\u00e1i c\u1ea3m…
\nFDA x\u00e1c \u0111\u1ecbnh hi\u1ec7u qu\u1ea3 c\u1ee7a suvorexant d\u1ef1a tr\u00ean 3 nghi\u00ean c\u1ee9u th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng v\u1edbi h\u01a1n 500 b\u1ec7nh nh\u00e2n. S\u1ed1 b\u1ec7nh nh\u00e2n d\u00f9ng suvorexant \u0111i v\u00e0o gi\u1ea5c ng\u1ee7 nhanh h\u01a1n v\u00e0 \u00edt th\u1ee9c gi\u1ea5c trong \u0111\u00eam h\u01a1n so v\u1edbi b\u1ec7nh nh\u00e2n nh\u00f3m d\u00f9ng gi\u1ea3 d\u01b0\u1ee3c, t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n th\u01b0\u1eddng g\u1eb7p l\u00e0 ng\u1ea7y ng\u1eadt ng\u00e0y h\u00f4m sau.
\nM\u1ed9t DORA kh\u00e1c l\u00e0 lemborexant (Essai Co)v\u1eeba \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn h\u1ed3 s\u01a1 NDA (new drug application) th\u00e1ng 1\/2019 sau khi c\u00f3 k\u1ebft qu\u1ea3 th\u1eed l\u00e2m s\u00e0ng pha II t\u1ed1t, v\u1edbi c\u00e1c DORA, hy v\u1ecdng nh\u1eefng th\u00e1ch th\u1ee9c c\u1ee7a m\u1ea5t ng\u1ee7 m\u00e3n t\u00ednh hay c\u1ea5p t\u00ednh s\u1ebd \u0111\u01b0\u1ee3c gi\u1ea3i quy\u1ebft.<\/p>\n

6. Tin bu\u1ed3n cho ng\u01b0\u1eddi m\u1ea5t ng\u1ee7 Vi\u1ec7t nam l\u00e0 t\u1ea5t c\u1ea3 c\u00e1c thu\u1ed1c \u0111\u01b0\u1ee3c AASM khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng n\u00f3i tr\u00ean \u0111\u1ec1u kh\u00f4ng c\u00f3 t\u1ea1i m\u1eb7t th\u1ecb tr\u01b0\u1eddng Vi\u1ec7t nam, ngo\u1ea1i tr\u1eeb \u00edt h\u00e0ng x\u00e1ch tay, c\u00e1c v\u0169 kh\u00ed cho y t\u1ebf VN trong vi\u1ec7c ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe t\u00e2m tr\u00ed v\u1eabn l\u00e0 m\u1ed9t v\u1ea5n \u0111\u1ec1 nan gi\u1ea3i (m\u1ed9t s\u1ed1 thu\u1ed1c m\u1edbi cho \u0111i\u1ec1u tr\u1ecb t\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t, tr\u1ea7m c\u1ea3m c\u0169ng ch\u01b0a s\u1eb5n c\u00f3)<\/p>\n

7. Tin vui l\u00e0 tr\u1ecb li\u1ec7u kh\u00f4ng d\u00f9ng thu\u1ed1c bao g\u1ed3m c\u00e1c bi\u1ec7n ph\u00e1p v\u1ec7 sinh gi\u1ea5c ng\u1ee7 (sleep hygiene), tr\u1ecb li\u1ec7u nh\u1eadn th\u1ee9c h\u00e0nh vi CBT (cognitive behavioral therapy) l\u00e0 bi\u1ec7n ph\u00e1p \u0111\u1ea7u ti\u00ean \u0111\u01b0\u1ee3c ch\u1ecdn l\u1ef1a, v\u00e0 th\u01b0\u1eddng c\u00f3 k\u1ebft qu\u1ea3 t\u1ed1t<\/p>\n

7.1 V\u1ec7 sinh gi\u1ea5c ng\u1ee7 :
\n– C\u1ed1 \u0111\u1ecbnh th\u1eddi \u0111i\u1ec3m \u0111i ng\u1ee7 (v\u00ed d\u1ee5 9-10 gi\u1edd t\u1ed1i), th\u1eddi gian th\u1ee9c d\u1eady v\u00e0o bu\u1ed5i s\u00e1ng (vi d\u1ee5 6 gi\u1edd)
\n– Kh\u00f4ng u\u1ed1ng tr\u00e0 cafe sau 3 gi\u1edd chi\u1ec1u
\n– B\u1ecf thu\u1ed1c l\u00e1, r\u01b0\u1ee3u, li\u1ec1u th\u1ea5p r\u01b0\u1ee3u g\u00e2y k\u00edch th\u00edch, li\u1ec1u cao g\u00e2y ng\u0169 ng\u1eafn h\u1ea1n v\u00e0 l\u00e0m th\u1ee9c gi\u1ea5c gi\u1eefa \u0111\u00eam
\n– Tr\u00e1nh u\u1ed1ng nhi\u1ec1u n\u01b0\u1edbc tr\u01b0\u1edbc khi ng\u1ee7 \u0111\u1ec3 h\u1ea1n ch\u1ebf \u0111i ti\u1ec3u, tr\u00e1nh \u0103n qu\u00e1 no tr\u01b0\u1edbc gi\u1edd ng\u0169.
\n– Kh\u00f4ng l\u00e0m vi\u1ec7c trong ph\u00f2ng ng\u1ee7, ph\u00f2ng ng\u1ee7 ch\u1ec9 d\u00f9ng cho vi\u1ec7c ng\u1ee7 v\u00e0 vi\u1ec7c \u1ea5y.
\n– Kh\u00f4ng d\u00f9ng \u0111i\u1ec7n tho\u1ea1i, ti vi, m\u00e1y t\u00ednh nhi\u1ec1u tr\u01b0\u1edbc khi ng\u1ee7
\n– N\u00ean t\u1eadp th\u1ec3 d\u1ee5c \u0111\u1ec1u \u0111\u1eb7n
\n– H\u1ea1n ch\u1ebf t\u1ed1i \u0111a ng\u1ee7 ng\u00e0y<\/p>\n

7.2 Tr\u1ecb li\u1ec7u nh\u1eadn th\u1ee9c h\u00e0nh vi
\n– \u0110i\u1ec1u tr\u1ecb nh\u1eadn th\u1ee9c : n\u1ed7i s\u01a1 m\u1ea5t ng\u1ee7 khi\u1ebfn ng\u01b0\u1eddi b\u1ec7nh kh\u00f3 ng\u1ee7 \u0111\u1ed3ng th\u1eddi lo l\u1eafng v\u1ec1 ch\u1ea5t l\u01b0\u1ee3ng s\u1ee9c kh\u1ecfe hay c\u00f4ng vi\u1ec7c ng\u00e0y h\u00f4m sau, nh\u1eb1m ph\u00e1 v\u1edf v\u00f2ng l\u1eabn qu\u1eabn n\u00e0y, b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c khuy\u00ean t\u00ecm c\u00e1ch r\u1ee7 b\u1ecf v\u00e0 tho\u00e1t kh\u1ecfi c\u00e1c suy ngh\u1ec9 g\u00e2y lo l\u1eafng, c\u00f3 th\u1ec3 d\u00f9ng m\u1ed9t nh\u1eadt k\u00fd ch\u00e9p l\u1ea1i c\u00e1c v\u1ea5n \u0111\u1ec1 ch\u01b0a gi\u1ea3i quy\u1ebft hay c\u00e1c v\u01b0\u1edbng b\u1eadn trong ng\u00e0y, v\u00ed d\u1ee5 c\u00f4 n\u00e0y \u0111\u1eb9p em kia xinh, h\u00f4m nay c\u00f3 li\u1ebfc m\u1eaft th\u1ea3 tim \u0111\u01b0a t\u00ecnh ai, sao th\u00e1ng n\u00e0y ch\u01b0a c\u00f3 l\u01b0\u01a1ng ch\u01b0a c\u00f3 period…
\n– Ki\u1ec3m so\u00e1t k\u00edch th\u00edch: ch\u1ec9 l\u00ean gi\u01b0\u1eddng ng\u1ee7 khi bu\u1ed3n ng\u1ee7 v\u00e0 r\u1eddi kh\u1ecfi gi\u01b0\u1eddng n\u1ebfu sau 20 ph\u00fat v\u1eabn ch\u01b0a ng\u1ee7 \u0111\u01b0\u1ee3c, \u0111i b\u1ed9, th\u01b0 gi\u00e3n, \u0103n u\u1ed1ng r\u1ea5t nh\u1eb9…sau \u0111\u00f3 tr\u1edf l\u1ea1i gi\u01b0\u1eddng. N\u1ebfu quay tr\u1edf l\u1ea1i gi\u01b0\u1eddng m\u00e0 v\u1eabn kh\u00f4ng th\u1ec3 ng\u1ee7 \u0111\u01b0\u1ee3c trong v\u00f2ng 20 ph\u00fat, quy tr\u00ecnh n\u1ea7y \u0111\u01b0\u1ee3c l\u1eb7p l\u1ea1i.
\n– Ph\u1ea3i th\u1ee9c gi\u1ea5c \u0111\u00fang gi\u1edd m\u1ed7i bu\u1ed5i s\u00e1ng, ngay c\u1ea3 ng\u00e0y ngh\u1ec9 cu\u1ed1i tu\u1ea7n
\n– Th\u01b0 gi\u00e3n : t\u1eadp th\u01b0 gi\u00e3n c\u01a1, l\u1ea7n l\u01b0\u1ee3t c\u00e1c c\u01a1 \u1edf m\u1eb7t vai c\u1ed5, sau \u0111\u00f3 xu\u1ed1ng tay v\u00e0 c\u00e1c chi d\u01b0\u1edbi, c\u00f3 th\u1ec3 k\u1ebft h\u1ee3p \u0111i\u1ec1u h\u00f2a nh\u1ecbp th\u1edf, ni\u1ec7m kinh, thi\u1ec1n hay yoga…<\/p>\n

8. M\u1ea5t ng\u0169 m\u00e3n t\u00ednh kh\u00f3 \u0111i\u1ec1u tr\u1ecb d\u1ee9t \u0111i\u1ec3m v\u00ec t\u00e1i \u0111i t\u00e1i l\u1ea1i, trong th\u1ef1c h\u00e0nh \u0111i\u1ec1u tr\u1ecb c\u1ea7n l\u01b0u \u00fd c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m c\u00e1 nh\u00e2n \u0111\u1ec3 c\u00e1 th\u1ec3 h\u00f3a \u0111i\u1ec1u tr\u1ecb, v\u00e0 tr\u01b0\u1edbc h\u1ebft c\u1ea7n \u0111i\u1ec1u tr\u1ecb t\u1ed1t c\u00e1c b\u1ec7nh th\u1ef1c th\u1ec3 hay t\u00e2m th\u1ea7n k\u00e8m theo…<\/p>\n

P\/S : B\u00e0i t\u1ed5ng h\u1ee3p c\u1ee7a m\u1ed9t d\u01b0\u1ee3c s\u0129, kh\u00f4ng ph\u1ea3i c\u1ee7a m\u1ed9t b\u00e1c s\u0129 n\u1ed9i khoa hay nh\u00e0 t\u00e2m th\u1ea7n h\u1ecdc, r\u1ea5t vui khi nh\u1eadn \u0111\u01b0\u1ee3c g\u00f3p \u00fd..\/.<\/p>\n

<\/p>\n

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1. R\u1ed1i lo\u1ea1n m\u1ea5t ng\u1ee7 \u0111\u01b0\u1ee3c \u0111\u1ecbnh ngh\u0129a l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n kh\u00f4ng do ho\u00e0n c\u1ea3nh hay c\u1ed1 \u00fd trong vi\u1ec7c kh\u1edfi \u0111\u1ea7u ho\u1eb7c duy tr\u00ec gi\u1ea5c ng\u1ee7 \u0111\u00eam m\u00e0 g\u00e2y ra nh\u1eefng \u1ea3nh h\u01b0\u1edfng n\u00e0o \u0111\u00f3 \u0111\u1ebfn t\u00ecnh tr\u1ea1ng th\u1ec3 ch\u1ea5t ng\u00e0y h\u00f4m sau. M\u1ea5t ng\u1ee7 \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh l\u00e0 m\u00e3n t\u00ednh (Chronic Insomnia) […]\n","protected":false},"author":1,"featured_media":4403,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4402","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/4402","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=4402"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/4402\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/4403"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=4402"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=4402"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=4402"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}