Esmya (ulipristal acetate 5 mg) l\u00e0 thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb u x\u01a1 t\u1eed cung. Ngay sau khi nh\u1eadn \u0111\u01b0\u1ee3c c\u00e1c b\u00e1o c\u00e1o d\u1ea5u hi\u1ec7u c\u1ea3nh gi\u00e1c d\u01b0\u1ee3c c\u1ee7a 4 tr\u01b0\u1eddng h\u1ee3p xu\u1ea5t hi\u1ec7n t\u1ed5n th\u01b0\u01a1ng gan n\u1eb7ng sau khi d\u00f9ng thu\u1ed1c n\u00e0y tr\u00ean l\u00e3nh th\u1ed5 ch\u00e2u \u00c2u, trong \u0111\u00f3 c\u00f3 3 tr\u01b0\u1eddng h\u1ee3p c\u1ea7n ph\u1ea3i gh\u00e9p gan, C\u01a1 quan Qu\u1ea3n l\u00ed d\u01b0\u1ee3c ch\u00e2u \u00c2u (EMA) \u0111\u00e3 b\u1eaft \u0111\u1ea7u \u0111\u00e1nh gi\u00e1 l\u1ea1i m\u1ed1i t\u01b0\u01a1ng quan l\u1ee3i \u00edch\/ nguy c\u01a1 c\u1ee7a Esmya. Trong th\u1eddi gian ch\u1edd \u0111\u1ee3i k\u1ebft lu\u1eadn c\u1ee7a EMA, C\u01a1 quan Qu\u1ea3n l\u00fd d\u01b0\u1ee3c Ph\u00e1p (ANSM), ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c chuy\u00ean gia y t\u1ebf c\u00f9ng Hi\u1ec7p h\u1ed9i b\u1ec7nh nh\u00e2n Fibrome info France, \u0111\u01b0a ra khuy\u1ebfn c\u00e1o th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng Esmya nh\u1eb1m b\u1ea3o \u0111\u1ea3m an to\u00e0n cho b\u1ec7nh nh\u00e2n.
\nC\u1ee5 th\u1ec3, c\u00e1c b\u00e1c s\u0129 khi k\u00ea \u0111\u01a1n Esmya c\u1ea7n tu\u00e2n th\u1ee7 c\u00e1c khuy\u1ebfn c\u00e1o sau \u0111\u00e2y:
\n– Y\u00eau c\u1ea7u ti\u1ebfn h\u00e0nh bilan gan tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Esmya;
\n– Kh\u00f4ng k\u00ea Esmya n\u1ebfu k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m b\u1ea5t th\u01b0\u1eddng (transaminase tr\u00ean 2 l\u1ea7n m\u1ee9c b\u00ecnh th\u01b0\u1eddng);
\n– \u0110\u1ed1i v\u1edbi c\u00e1c b\u1ec7nh nh\u00e2n \u0111ang \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c n\u00e0y, c\u00f3 th\u1ec3 ch\u1ec9 \u0111\u1ecbnh l\u00e0m bilan gan khi th\u0103m kh\u00e1m theo d\u00f5i;
\n– Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Esmya, n\u1ebfu b\u1ec7nh nh\u00e2n xu\u1ea5t hi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng nghi c\u00f3 th\u1ec3 do t\u1ed5n th\u01b0\u01a1ng gan (bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au h\u1ea1 s\u01b0\u1eddn ph\u1ea3i, ch\u00e1n \u0103n, suy nh\u01b0\u1ee3c, v\u00e0ng da…) ph\u1ea3i ng\u1eebng thu\u1ed1c ngay l\u1eadp t\u1ee9c v\u00e0 ch\u1ec9 \u0111\u1ecbnh l\u00e0m bilan gan. T\u00f9y theo k\u1ebft qu\u1ea3, b\u00e1c s\u0129 s\u1ebd cho s\u1eed d\u1ee5ng thu\u1ed1c tr\u1edf l\u1ea1i ho\u1eb7c kh\u00f4ng.
\nB\u1ec7nh nh\u00e2n c\u00f3 c\u00e2u h\u1ecfi ho\u1eb7c lo l\u1eafng g\u00ec li\u00ean quan t\u1edbi ch\u1ee7 \u0111\u1ec1 n\u00e0y ph\u1ea3i li\u00ean h\u1ec7 ngay v\u1edbi b\u00e1c s\u0129 ph\u1ee5 khoa.
\nC\u00e1c b\u00e1c s\u0129 v\u00e0 d\u01b0\u1ee3c s\u0129 c\u1ea7n cung c\u1ea5p l\u1ea1i cho b\u1ec7nh nh\u00e2n t\u00e0i li\u1ec7u th\u00f4ng tin li\u00ean quan \u0111\u1ebfn th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng Esmya khi k\u00ea \u0111\u01a1n ho\u1eb7c c\u1ea5p ph\u00e1t thu\u1ed1c.
\nL\u01b0u \u00fd, ho\u1ea1t ch\u1ea5t ulipristal c\u0169ng c\u00f3 trong th\u00e0nh ph\u1ea7n c\u1ee7a thu\u1ed1c tr\u00e1nh thai kh\u1ea9n c\u1ea5p EllaOne. Tuy nhi\u00ean, cho t\u1edbi nay ch\u01b0a ghi nh\u1eadn b\u1ea5t c\u1ee9 tr\u01b0\u1eddng h\u1ee3p t\u1ed5n th\u01b0\u01a1ng gan n\u1eb7ng n\u00e0o li\u00ean quan t\u1edbi EllaOne.
\n(T\u1ea1i Vi\u1ec7t Nam, Esmya v\u00e0 Ella \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p l\u01b0u h\u00e0nh t\u01b0\u01a1ng \u1ee9ng theo quy\u1ebft \u0111\u1ecbnh s\u1ed1 214\/QLD-\u0110K v\u00e0 210\/QLD-\u0110K c\u1ee7a C\u1ee5c Qu\u1ea3n l\u00fd D\u01b0\u1ee3c – B\u1ed9 Y t\u1ebf).<\/p>\n