{"id":4110,"date":"2019-03-09T09:56:46","date_gmt":"2019-03-09T02:56:46","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?p=4110"},"modified":"2021-11-30T10:00:18","modified_gmt":"2021-11-30T03:00:18","slug":"ema-cap-nhat-thong-tin-an-toan-ve-retinoid","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/ema-cap-nhat-thong-tin-an-toan-ve-retinoid\/","title":{"rendered":"EMA: C\u1eadp nh\u1eadt th\u00f4ng tin an to\u00e0n v\u1ec1 retinoid"},"content":{"rendered":"<p>Sau khi ho\u00e0n th\u00e0nh t\u1ed5ng h\u1ee3p d\u1eef li\u1ec7u v\u1ec1 c\u00e1c thu\u1ed1c ch\u1ee9a <a href=\"https:\/\/nhathuocngocanh.com\/hoat-chat\/retinoids\/\" rel=\"noopener\">retinoid<\/a>, C\u01a1 quan qu\u1ea3n l\u00ed d\u01b0\u1ee3c ch\u00e2u \u00c2u (EMA) \u0111\u00e3 x\u00e1c nh\u1eadn r\u1eb1ng c\u1ea7n ph\u1ea3i c\u1eadp nh\u1eadt c\u00e1c bi\u1ec7n ph\u00e1p d\u1ef1 ph\u00f2ng ti\u1ebfp x\u00fac retinoid trong thai k\u00ec. Ngo\u00e0i ra, c\u1ea3nh b\u00e1o v\u1ec1 kh\u1ea3 n\u0103ng xu\u1ea5t hi\u1ec7n c\u00e1c r\u1ed1i lo\u1ea1n th\u1ea7n kinh &#8211; t\u00e2m th\u1ea7n (nh\u01b0 tr\u1ea7m c\u1ea3m, lo \u00e2u v\u00e0 thay \u0111\u1ed5i kh\u00ed s\u1eafc) khi d\u00f9ng thu\u1ed1c c\u0169ng s\u1ebd \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o th\u00f4ng tin tr\u00ean nh\u00e3n thu\u1ed1c \u0111\u1ed1i v\u1edbi c\u00e1c retinoid \u0111\u01b0\u1eddng u\u1ed1ng.<\/p>\n<p>C\u00e1c thu\u1ed1c retinoid \u0111\u01b0\u1ee3c n\u00f3i \u0111\u1ebfn bao g\u1ed3m c\u00e1c ho\u1ea1t ch\u1ea5t acitretin, adapalene, alitretinoin, bexarotene, isotretinoin, tazarotene v\u00e0 tretinoin. C\u00e1c ho\u1ea1t ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng theo \u0111\u01b0\u1eddng u\u1ed1ng ho\u1eb7c kem hay gel b\u00f4i da \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u00e1c t\u00ecnh tr\u1ea1ng b\u1ec7nh l\u00ed n\u1eb7ng tr\u00ean da, bao g\u1ed3m m\u1ee5n tr\u1ee9ng c\u00e1 n\u1eb7ng v\u00e0 v\u1ea3y n\u1ebfn. M\u1ed9t s\u1ed1 retinoid c\u00f2n \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb m\u1ed9t s\u1ed1 b\u1ec7nh ung th\u01b0.<\/p>\n<p>T\u1ed5ng quan d\u1eef li\u1ec7u x\u00e1c nh\u1eadn r\u1eb1ng c\u00e1c thu\u1ed1c retinoid \u0111\u01b0\u1eddng u\u1ed1ng c\u00f3 th\u1ec3 g\u00e2y h\u1ea1i cho thai nhi v\u00e0 kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng trong th\u1eddi k\u00ec mang thai. Th\u00eam v\u00e0o \u0111\u00f3, c\u00e1c retinoid \u0111\u01b0\u1eddng u\u1ed1ng acitretin, alitretinoin v\u00e0 isotretinoin d\u00f9ng trong \u0111i\u1ec1u tr\u1ecb c\u00e1c t\u00ecnh tr\u1ea1ng b\u1ec7nh l\u00ed n\u1eb7ng tr\u00ean da ph\u1ea3i \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u ki\u1ec7n c\u1ee7a ch\u01b0\u01a1ng tr\u00ecnh v\u1ec1 d\u1ef1 ph\u00f2ng ti\u1ebfp x\u00fac trong l\u1ea7n mang thai m\u1edbi \u1edf ph\u1ee5 n\u1eef c\u00f3 kh\u1ea3 n\u0103ng sinh \u0111\u1ebb.<\/p>\n<p>C\u00e1c retinoid d\u00f9ng t\u1ea1i ch\u1ed7 (ngo\u00e0i da) c\u0169ng kh\u00f4ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 c\u00f3 d\u1ef1 \u0111\u1ecbnh mang thai.<\/p>\n<p>Xem th\u00eam th\u00f4ng tin t\u1ea1i\u00a0<a href=\"https:\/\/www.ema.europa.eu\/en\/news\/updated-measures-pregnancy-prevention-during-retinoid-use\" rel=\"noopener\">https:\/\/www.ema.europa.eu\/en\/news\/updated-measures-pregnancy-prevention-during-retinoid-use<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sau khi ho\u00e0n th\u00e0nh t\u1ed5ng h\u1ee3p d\u1eef li\u1ec7u v\u1ec1 c\u00e1c thu\u1ed1c ch\u1ee9a retinoid, C\u01a1 quan qu\u1ea3n l\u00ed d\u01b0\u1ee3c ch\u00e2u \u00c2u (EMA) \u0111\u00e3 x\u00e1c nh\u1eadn r\u1eb1ng c\u1ea7n ph\u1ea3i c\u1eadp nh\u1eadt c\u00e1c bi\u1ec7n ph\u00e1p d\u1ef1 ph\u00f2ng ti\u1ebfp x\u00fac retinoid trong thai k\u00ec. Ngo\u00e0i ra, c\u1ea3nh b\u00e1o v\u1ec1 kh\u1ea3 n\u0103ng xu\u1ea5t hi\u1ec7n c\u00e1c r\u1ed1i lo\u1ea1n th\u1ea7n kinh &#8211; [&#8230;]\n","protected":false},"author":1,"featured_media":4111,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4110","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/4110","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=4110"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/4110\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/4111"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=4110"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=4110"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=4110"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}