{"id":4025,"date":"2019-03-06T21:12:07","date_gmt":"2019-03-06T14:12:07","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?p=4025"},"modified":"2019-03-06T21:12:30","modified_gmt":"2019-03-06T14:12:30","slug":"ansm-cong-bo-tinh-hinh-tieu-thu-thuoc-giam-dau-opioid-tai-phap","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/ansm-cong-bo-tinh-hinh-tieu-thu-thuoc-giam-dau-opioid-tai-phap\/","title":{"rendered":"ANSM c\u00f4ng b\u1ed1 t\u00ecnh h\u00ecnh ti\u00eau th\u1ee5 thu\u1ed1c gi\u1ea3m \u0111au opioid t\u1ea1i Ph\u00e1p."},"content":{"rendered":"<p>Vi\u1ec7c ph\u00f2ng ng\u1eeba c\u00e1c r\u1ee7i ro li\u00ean quan \u0111\u1ebfn thu\u1ed1c gi\u1ea3m \u0111au opiod l\u00e0 m\u1ed9t trong nh\u1eefng m\u1ed1i quan t\u00e2m h\u00e0ng \u0111\u1ea7u c\u1ee7a c\u00e1c c\u01a1 quan y t\u1ebf t\u1ea1i Ph\u00e1p. <strong>ANSM v\u1eeba c\u00f4ng b\u1ed1 m\u1ed9t b\u00e1o c\u00e1o v\u1ec1 t\u00ecnh h\u00ecnh ti\u00eau th\u1ee5 thu\u1ed1c gi\u1ea3m \u0111au opiod t\u1ea1i Ph\u00e1p v\u00e0 \u0111\u00e2y l\u00e0 m\u1ed9t ph\u1ea7n trong ch\u01b0\u01a1ng tr\u00ecnh gi\u00e1m s\u00e1t to\u00e0n c\u1ea7u v\u1ec1 vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c gi\u1ea3m \u0111au<\/strong>. Trong v\u00f2ng 10 n\u0103m vi\u1ec7c ti\u00eau th\u1ee5 thu\u1ed1c gi\u1ea3m \u0111au \u0111\u00e3 t\u0103ng \u0111\u00e1ng k\u1ec3 \u1edf Ph\u00e1p. \u0110\u00e2y c\u00f3 th\u1ec3 l\u00e0 h\u1ec7 qu\u1ea3 c\u1ee7a ch\u00ednh s\u00e1ch c\u1ea3i thi\u1ec7n vi\u1ec7c ki\u1ec3m so\u00e1t c\u01a1n \u0111au \u0111\u01b0\u1ee3c B\u1ed9 y t\u1ebf Ph\u00e1p tri\u1ec3n khai t\u1eeb n\u0103m 1998.<\/p>\n<p>Trong v\u00f2ng 10 n\u0103m vi\u1ec7c ti\u00eau th\u1ee5 thu\u1ed1c gi\u1ea3m \u0111au \u0111\u00e3 t\u0103ng \u0111\u00e1ng k\u1ec3 \u1edf Ph\u00e1p. \u0110\u00e2y c\u00f3 th\u1ec3 l\u00e0 h\u1ec7 qu\u1ea3 c\u1ee7a ch\u00ednh s\u00e1ch c\u1ea3i thi\u1ec7n vi\u1ec7c ki\u1ec3m so\u00e1t c\u01a1n \u0111au \u0111\u01b0\u1ee3c B\u1ed9 y t\u1ebf Ph\u00e1p tri\u1ec3n khai t\u1eeb n\u0103m 1998.<\/p>\n<p>B\u00ean c\u1ea1nh \u0111\u00f3, ANSM c\u0169ng \u0111\u1ed3ng th\u1eddi quan s\u00e1t th\u1ea5y s\u1ef1 gia t\u0103ng t\u00ecnh tr\u1ea1ng l\u1ea1m d\u1ee5ng thu\u1ed1c gi\u1ea3m \u0111au g\u00e2y nghi\u1ec7n c\u0169ng nh\u01b0 ng\u1ed9 \u0111\u1ed9c v\u00e0 t\u1eed vong li\u00ean quan \u0111\u1ebfn vi\u1ec7c s\u1eed d\u1ee5ng gi\u1ea3m \u0111au opioid ho\u1ea1t l\u1ef1c y\u1ebfu v\u00e0 m\u1ea1nh.Tuy nhi\u00ean, t\u00ecnh h\u00ecnh n\u00e0y kh\u00f4ng t\u01b0\u01a1ng \u0111\u1ed3ng v\u1edbi nh\u1eefng quan s\u00e1t t\u01b0\u01a1ng t\u1ef1 t\u1ea1i Hoa K\u1ef3 v\u00e0 Canada.<\/p>\n<p>Th\u00e1ch th\u1ee9c \u0111\u1ed1i v\u1edbi c\u00e1c c\u01a1 quan \u00fd t\u1ebf t\u1ea1i Ph\u00e1p l\u00e0 b\u1ea3o \u0111\u1ea3m vi\u1ec7c s\u1eed d\u1ee5ng h\u1ee3p l\u00fd <strong>thu\u1ed1c gi\u1ea3m \u0111au opioid<\/strong> m\u00e0 kh\u00f4ng h\u1ea1n ch\u1ebf vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c n\u00e0y trong \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>T\u1ea1i Ph\u00e1p, ANSM th\u01b0\u1eddng xuy\u00ean th\u1ef1c hi\u1ec7n vi\u1ec7c ki\u1ec3m so\u00e1t thu\u1ed1c gi\u1ea3m \u0111au opioid trong c\u00e1c ho\u1ea1t \u0111\u1ed9ng k\u00ea \u0111\u01a1n v\u00e0 pha ch\u1ebf c\u0169ng nh\u01b0 trong cung c\u1ea5p th\u00f4ng tin cho c\u00e1c chuy\u00ean gia y t\u1ebf v\u00e0 c\u1ed9ng \u0111\u1ed3ng. ANSM li\u00ean t\u1ee5c theo d\u00f5i ch\u1eb7t ch\u1ebd vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c v\u00e0 nh\u1eefng nguy c\u01a1 li\u00ean quan.<\/p>\n<p>Nh\u1eefng n\u1ed9i dung ch\u00ednh c\u1ee7a b\u00e1o c\u00e1o g\u1ed3m:<\/p>\n<p>Theo d\u1eef li\u1ec7u b\u1ea3o hi\u1ec3m y t\u1ebf, g\u1ea7n 10 tri\u1ec7u ng\u01b0\u1eddi Ph\u00e1p \u0111\u01b0\u1ee3c k\u00ea \u0111\u01a1n thu\u1ed1c gi\u1ea3m \u0111au opioid n\u0103m 2015. N\u0103m 2017, thu\u1ed1c gi\u1ea3m \u0111au \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ph\u1ed5 bi\u1ebfn nh\u1ea5t t\u1ea1i Ph\u00e1p l\u00e0 tramadol, x\u1ebfp sau \u0111\u00f3 l\u00e0 codein d\u1ea1ng k\u1ebft h\u1ee3p v\u00e0 thu\u1ed1c nh\u00f3m opioid k\u1ebft h\u1ee3p v\u1edbi paracetamol, morphin, oxycodon (hi\u1ec7n \u0111\u01b0\u1ee3c ti\u00eau th\u1ee5 g\u1ea7n nh\u01b0 morphin) v\u00e0 sau \u0111\u00f3 fentanyl t\u00e1c d\u1ee5ng nhanh qua da v\u00e0 xuy\u00ean m\u00e0ng.<br \/>\nT\u1eeb n\u0103m 2006 \u0111\u1ebfn 2017, vi\u1ec7c k\u00ea \u0111\u01a1n thu\u1ed1c opioid c\u00f3 ho\u1ea1t t\u00ednh m\u1ea1nh t\u0103ng kho\u1ea3ng 150%. Oxycodine l\u00e0 thu\u1ed1c gi\u1ea3m \u0111au opioid \u0111\u00e1nh d\u1ea5u s\u1ef1 gia t\u0103ng l\u1edbn nh\u1ea5t.<br \/>\nNg\u01b0\u1ee3c l\u1ea1i, vi\u1ec7c ti\u00eau th\u1ee5 nh\u00f3m opioid c\u00f3 ho\u1ea1t t\u00ednh y\u1ebfu th\u00ec t\u01b0\u01a1ng \u0111\u1ed1i \u1ed5n \u0111\u1ecbnh. Vi\u1ec7c r\u00fat dextropropoxyphene ra kh\u1ecfi th\u1ecb tr\u01b0\u1eddng v\u00e0o n\u0103m 2011 d\u1eabn \u0111\u1ebfn vi\u1ec7c t\u0103ng ti\u00eau th\u1ee5 c\u00e1c thu\u1ed1c gi\u1ea3m \u0111au opioid y\u1ebfu kh\u00e1c, \u0111\u1eb7c bi\u1ec7t l\u00e0 tramadol. \u0110\u00e2y l\u00e0 thu\u1ed1c gi\u1ea3m \u0111au \u0111\u01b0\u1ee3c ti\u00eau th\u1ee5 nhi\u1ec1u nh\u1ea5t v\u1edbi m\u1ee9c t\u0103ng 68% t\u1eeb n\u0103m 2006 \u0111\u1ebfn 2017.<br \/>\nNh\u00f3m opioid l\u00e0 nh\u00f3m thu\u1ed1c quan tr\u1ecdng v\u00e0 kh\u00f4ng th\u1ec3 ph\u1ee7 nh\u1eadn vai tr\u00f2 trong vi\u1ec7c ki\u1ec3m so\u00e1t c\u01a1n \u0111au. Nh\u00f3m opioid v\u1eabn \u0111\u01b0\u1ee3c ti\u00eau th\u1ee5 \u00edt h\u01a1n so v\u1edbi thu\u1ed1c gi\u1ea3m \u0111au kh\u00f4ng streroid (paracetamol, aspirin, NSAID). Tuy nhi\u00ean, vi\u1ec7c s\u1eed d\u1ee5ng nh\u00f3m thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 d\u1eabn d\u1ebfn c\u00e1c bi\u1ebfn ch\u1ee9ng nghi\u00eam trong. V\u1ea5n \u0111\u1ebf n\u00e0y ch\u1ee7 y\u1ebfu \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn nh\u1eefng b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng thu\u1ed1c \u0111\u1ec3 gi\u1ea3m \u0111au v\u00e0 t\u0103ng d\u1ea7n s\u1ef1 l\u1ec7 thu\u1ed9c thu\u1ed1c v\u00e0 \u0111\u00f4i khi s\u1eed d\u1ee5ng ngo\u00e0i ch\u1ec9 \u0111\u1ecbnh ban \u0111\u1ea7u. Do \u0111\u00f3, s\u1ed1 ca nh\u1eadp vi\u1ec7n li\u00ean quan \u0111\u1ebfn thu\u1ed1c gi\u1ea3m \u0111au opioid \u0111\u01b0\u1ee3c k\u00ea \u0111\u01a1n c\u1ee7a b\u00e1c s\u0129 \u0111\u00e3 t\u0103ng 167% t\u1eeb n\u0103m 2000 \u0111\u1ebfn 2017 v\u00e0 t\u0103ng t\u1eeb 15 \u0111\u1ebfn 40 ca nh\u1eadp vi\u1ec7n tr\u00ean m\u1ed9t tri\u1ec7u d\u00e2n. S\u1ed1 c\u1ea3 t\u1eed vong li\u00ean quan \u0111\u1ebfn opioid t\u0103ng 146% t\u1eeb n\u0103m 2000 \u0111\u1ebfn 2015 v\u1edbi \u00edt nh\u1ea5t 4 tr\u01b0\u1eddng h\u1ee3p t\u1eed vong m\u1ed7i tu\u1ea7n.<br \/>\nV\u00ec v\u1eady, ANSM s\u1ebd t\u00edch c\u1ef1c tri\u1ec3n khai c\u00e1c bi\u1ec7n ph\u00e1p t\u0103ng c\u01b0\u1eddng s\u1eed d\u1ee5ng nh\u00f3m thu\u1ed1c n\u00e0y h\u1ee3p l\u00fd v\u00e0 an to\u00e0n, h\u1ea1n ch\u1ebf t\u00ecnh tr\u1ea1ng l\u1ea1m d\u1ee5ng v\u00e0 ph\u1ee5 thu\u1ed9c v\u00e0o thu\u1ed1c trong giai \u0111o\u1ea1n t\u1edbi.<\/p>\n<p>Ngu\u1ed3n: <a href=\"https:\/\/ansm.sante.fr\/S-informer\/Actualite\/Antalgiques-opioides-l-ANSM-publie-un-etat-des-lieux-de-la-consommation-en-France-Point-d-Information\" rel=\"noopener\">https:\/\/ansm.sante.fr\/S-informer\/Actualite\/Antalgiques-opioides-l-ANSM-publie-un-etat-des-lieux-de-la-consommation-en-France-Point-d-Information<\/a><\/p>\n<p>Ng\u01b0\u1eddi t\u1ed5ng h\u1ee3p: DS. V\u0169 \u0110\u1ee9c Ho\u00e0n \u2013 D\u01b0\u01a1ng Kh\u00e1nh Linh<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vi\u1ec7c ph\u00f2ng ng\u1eeba c\u00e1c r\u1ee7i ro li\u00ean quan \u0111\u1ebfn thu\u1ed1c gi\u1ea3m \u0111au opiod l\u00e0 m\u1ed9t trong nh\u1eefng m\u1ed1i quan t\u00e2m h\u00e0ng \u0111\u1ea7u c\u1ee7a c\u00e1c c\u01a1 quan y t\u1ebf t\u1ea1i Ph\u00e1p. ANSM v\u1eeba c\u00f4ng b\u1ed1 m\u1ed9t b\u00e1o c\u00e1o v\u1ec1 t\u00ecnh h\u00ecnh ti\u00eau th\u1ee5 thu\u1ed1c gi\u1ea3m \u0111au opiod t\u1ea1i Ph\u00e1p v\u00e0 \u0111\u00e2y l\u00e0 m\u1ed9t ph\u1ea7n trong ch\u01b0\u01a1ng [&#8230;]\n","protected":false},"author":1,"featured_media":4026,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4025","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/4025","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=4025"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/4025\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/4026"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=4025"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=4025"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=4025"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}