{"id":3805,"date":"2019-02-24T12:17:01","date_gmt":"2019-02-24T05:17:01","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?p=3805"},"modified":"2019-02-25T12:17:33","modified_gmt":"2019-02-25T05:17:33","slug":"fda-canh-bao-gia-tang-nguy-co-tu-vong-khi-su-dung-thuoc-dieu-tri-gout-uloric-febuxostat","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/fda-canh-bao-gia-tang-nguy-co-tu-vong-khi-su-dung-thuoc-dieu-tri-gout-uloric-febuxostat\/","title":{"rendered":"FDA: C\u1ea3nh b\u00e1o gia t\u0103ng nguy c\u01a1 t\u1eed vong khi s\u1eed d\u1ee5ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb Gout Uloric (Febuxostat)"},"content":{"rendered":"<p><strong>FDA \u0111\u00e3 \u0111\u01b0a ra k\u1ebft lu\u1eadn c\u00f3 nguy c\u01a1 gia t\u0103ng t\u1eed vong khi s\u1eed d\u1ee5ng thu\u1ed1c Uloric (Febuxostat) khi so s\u00e1nh v\u1edbi c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb Gout kh\u00e1c nh\u01b0 Allopurinol<\/strong>. K\u1ebft lu\u1eadn n\u00e0y d\u1ef1a tr\u00ean c\u00e1c k\u1ebft qu\u1ea3 thu \u0111\u01b0\u1ee3c c\u1ee7a m\u1ed9t \u0111\u00e1nh gi\u00e1 chuy\u00ean s\u00e2u v\u1ec1 c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng v\u1ec1 t\u00ednh an to\u00e0n v\u00e0 d\u1eef li\u1ec7u cho th\u1ea5y vi\u1ec7c s\u1eed d\u1ee5ng Uloric l\u00e0m t\u0103ng nguy c\u01a1 t\u1eed vong do c\u00e1c v\u1ea5n \u0111\u1ec1 tim m\u1ea1ch v\u00e0 c\u00e1c nguy\u00ean nh\u00e2n kh\u00e1c.<\/p>\n<p>FDA \u0111\u00e3 \u0111\u01b0a ra k\u1ebft lu\u1eadn c\u00f3 nguy c\u01a1 gia t\u0103ng t\u1eed vong khi s\u1eed d\u1ee5ng thu\u1ed1c Uloric (Febuxostat) khi so s\u00e1nh v\u1edbi c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb Gout kh\u00e1c nh\u01b0 Allopurinol. K\u1ebft lu\u1eadn n\u00e0y d\u1ef1a tr\u00ean c\u00e1c k\u1ebft qu\u1ea3 thu \u0111\u01b0\u1ee3c c\u1ee7a m\u1ed9t \u0111\u00e1nh gi\u00e1 chuy\u00ean s\u00e2u v\u1ec1 c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng v\u1ec1 t\u00ednh an to\u00e0n v\u00e0 d\u1eef li\u1ec7u cho th\u1ea5y vi\u1ec7c s\u1eed d\u1ee5ng Uloric l\u00e0m t\u0103ng nguy c\u01a1 t\u1eed vong do c\u00e1c v\u1ea5n \u0111\u1ec1 tim m\u1ea1ch v\u00e0 c\u00e1c nguy\u00ean nh\u00e2n kh\u00e1c.<\/p>\n<h2>Th\u00f4ng tin chung<\/h2>\n<p>Uloric \u0111\u01b0\u1ee3c FDA ch\u1ea5p thu\u1eadn v\u00e0o n\u0103m 2009 \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb Gout &#8211; m\u1ed9t b\u1ec7nh vi\u00eam kh\u1edbp \u1edf ng\u01b0\u1eddi l\u1edbn. Gout kh\u1edfi ph\u00e1t khi n\u1ed3ng \u0111\u1ed9 acid uric trong m\u00e1u t\u0103ng cao, g\u00e2y s\u01b0ng, \u0111\u1ecf, \u0111au \u1edf m\u1ed9t ho\u1eb7c nhi\u1ec1u kh\u1edbp. Uloric c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m h\u1ea1 n\u1ed3ng \u0111\u1ed9 acid uric trong m\u00e1u xu\u1ed1ng. Gout l\u00e0 m\u1ed9t b\u1ec7nh m\u00e3n t\u00ednh, \u1ea3nh \u0111\u1ebfn g\u1ea7n 8.3 tri\u1ec7u ng\u01b0\u1eddi \u1edf M\u1ef9. S\u1ed1 l\u01b0\u1ee3ng thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb Gout v\u1eabn c\u00f2n r\u1ea5t h\u1ea1n ch\u1ebf v\u00e0 nhu c\u1ea7u ch\u1eefa tr\u1ecb c\u0103n b\u1ec7nh n\u00e0y v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c \u0111\u00e1p \u1ee9ng \u0111\u1ea7y \u0111\u1ee7.<\/p>\n<h2>C\u00e1c khuy\u1ebfn c\u00e1o<\/h2>\n<p>B\u1ec7nh nh\u00e2n n\u00ean tham kh\u1ea3o \u00fd ki\u1ebfn chuy\u00ean gia y t\u1ebf n\u1ebfu c\u00f3 ti\u1ec1n s\u1eed m\u1eafc c\u00e1c b\u1ec7nh tim m\u1ea1ch ho\u1eb7c \u0111\u1ed9t qu\u1ef5, v\u00e0 c\u1ea7n c\u00e2n nh\u1eafc gi\u1eefa l\u1ee3i \u00edch v\u00e0 nguy c\u01a1 khi s\u1eed d\u1ee5ng Uloric \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb Gout. Kh\u00f4ng \u0111\u01b0\u1ee3c ng\u01b0ng s\u1eed d\u1ee5ng thu\u1ed1c m\u00e0 kh\u00f4ng c\u00f3 h\u01b0\u1edbng d\u1eabn c\u1ee7a c\u00e1n b\u1ed9 y t\u1ebf, v\u00ec c\u00f3 th\u1ec3 khi\u1ebfn b\u1ec7nh Gout chuy\u1ec3n bi\u1ebfn x\u1ea5u. Trong qu\u00e1 tr\u00ecnh s\u1eed d\u1ee5ng thu\u1ed1c, c\u1ea7n b\u00e1o ngay cho c\u00e1n b\u1ed9 y t\u1ebf n\u1ebfu b\u1ec7nh nh\u00e2n g\u1eb7p ph\u1ea3i c\u00e1c tri\u1ec7u ch\u1ee9ng sau:<\/p>\n<ul>\n<li>\u0110au ng\u1ef1c<\/li>\n<li>Kh\u00f3 th\u1edf<\/li>\n<li>Nh\u1ecbp tim nhanh ho\u1eb7c kh\u00f4ng \u0111\u1ec1u<\/li>\n<li>T\u00ea li\u1ec7t, y\u1ebfu n\u1eeda ng\u01b0\u1eddi<\/li>\n<li>Ch\u00f3ng m\u1eb7t<\/li>\n<li>Kh\u00f3 n\u00f3i<\/li>\n<li>\u0110au \u0111\u1ea7u d\u1eef d\u1ed9i k\u1ecbch ph\u00e1t<\/li>\n<\/ul>\n<p>C\u00e1n b\u1ed9 y t\u1ebf ch\u1ec9 n\u00ean ch\u1ec9 \u0111\u1ecbnh Uloric \u1edf b\u1ec7nh nh\u00e2n kh\u00f4ng dung n\u1ea1p ho\u1eb7c th\u1ea5t b\u1ea1i khi \u0111i\u1ec1u tr\u1ecb Gout b\u1eb1ng allopurinol. Khuy\u1ebfn c\u00e1o b\u1ec7nh nh\u00e2n v\u1ec1 c\u00e1c nguy c\u01a1 tim m\u1ea1ch do Uloric v\u00e0 d\u1eb7n d\u00f2 h\u1ecd c\u1ea7n b\u00e1o c\u00e1o ngay khi g\u1eb7p ph\u1ea3i c\u00e1c tri\u1ec7u ch\u1ee9ng k\u1ec3 tr\u00ean.<\/p>\n<p>Ngu\u1ed3n: <a href=\"https:\/\/www.fda.gov\/Safety\/MedWatch\/SafetyInformation\/SafetyAlertsforHumanMedicalProducts\/ucm631824.htm\" rel=\"noopener\">https:\/\/www.fda.gov\/Safety\/MedWatch\/SafetyInformation\/SafetyAlertsforHumanMedicalProducts\/ucm631824.htm<\/a><\/p>\n<p>Ng\u01b0\u1eddi t\u1ed5ng h\u1ee3p: \u0110\u1ed7 Thu Thanh &#8211; Nguy\u1ec5n Ph\u01b0\u01a1ng Th\u00fay<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>FDA \u0111\u00e3 \u0111\u01b0a ra k\u1ebft lu\u1eadn c\u00f3 nguy c\u01a1 gia t\u0103ng t\u1eed vong khi s\u1eed d\u1ee5ng thu\u1ed1c Uloric (Febuxostat) khi so s\u00e1nh v\u1edbi c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb Gout kh\u00e1c nh\u01b0 Allopurinol. K\u1ebft lu\u1eadn n\u00e0y d\u1ef1a tr\u00ean c\u00e1c k\u1ebft qu\u1ea3 thu \u0111\u01b0\u1ee3c c\u1ee7a m\u1ed9t \u0111\u00e1nh gi\u00e1 chuy\u00ean s\u00e2u v\u1ec1 c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng v\u1ec1 t\u00ednh [&#8230;]\n","protected":false},"author":1,"featured_media":3806,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3805","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/3805","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=3805"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/3805\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/3806"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=3805"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=3805"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=3805"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}