{"id":22121,"date":"2019-09-30T09:28:32","date_gmt":"2019-09-30T02:28:32","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?p=22121"},"modified":"2020-10-31T12:17:49","modified_gmt":"2020-10-31T05:17:49","slug":"ciprofloxacin","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/ciprofloxacin\/","title":{"rendered":"Ciprofloxacin – Kh\u00e1ng sinh nh\u00f3m Fluoroquinolon th\u1ebf h\u1ec7 hai"},"content":{"rendered":"

Ciprofloxacin<\/strong> l\u00e0 kh\u00e1ng sinh th\u1ebf h\u1ec7 2 thu\u1ed9c nh\u00f3m Fluoroquinolon th\u01b0\u1eddng d\u00f9ng trong \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n n\u1eb7ng v\u00e0 nghi\u00eam tr\u1ecdng. Trong b\u00e0i n\u00e0y, ch\u00fang t\u00f4i xin g\u1eedi \u0111\u1ebfn \u0111\u1ed9c gi\u1ea3 nh\u1eefng th\u00f4ng tin chi ti\u1ebft v\u00e0 ch\u00ednh x\u00e1c nh\u1ea5t v\u1ec1 Ho\u1ea1t ch\u1ea5t Ciprofloxacin<\/strong>: l\u00e0 thu\u1ed1c g\u00ec<\/strong>? T\u00e1c d\u1ee5ng<\/strong> – C\u00f4ng d\u1ee5ng c\u1ee7a Ciprofloxacin<\/strong>? Li\u1ec1u d\u00f9ng v\u00e0 nh\u1eefng l\u01b0u \u00fd quan tr\u1ecdng khi d\u00f9ng thu\u1ed1c.<\/p>\n

Ciprofloxacin l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n
Ciprofloxacin<\/strong> l\u00e0 m\u1ed9t kh\u00e1ng sinh b\u00e1n t\u1ed5ng h\u1ee3p nh\u00f3m Fluoroquinolon th\u1ebf h\u1ec7 th\u1ee9 hai c\u00f3 ph\u1ed5 kh\u00e1ng khu\u1ea9n r\u1ed9ng. Th\u01b0\u1eddng d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb m\u1ed9t s\u1ed1 b\u1ec7nh nhi\u1ec5m khu\u1ea9n n\u1eb7ng m\u00e0 c\u00e1c kh\u00e1ng sinh th\u00f4ng th\u01b0\u1eddng kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng nh\u01b0 vi\u00eam \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u tr\u00ean v\u00e0 d\u01b0\u1edbi, nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng m\u1eadt, nhi\u1ec5m khu\u1ea9n x\u01b0\u01a1ng kh\u1edbp, nhi\u1ec5m khu\u1ea9n tai m\u0169i h\u1ecdng v\u00e0 \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p d\u01b0\u1edbi, vi\u00eam x\u01b0\u01a1ng ch\u1eadu, vi\u00eam ph\u00fac m\u1ea1c\u2026<\/p>\n
Ciprofloxacin \u0111\u01b0\u1ee3c d\u00f9ng d\u01b0\u1edbi c\u00e1c d\u1ea1ng:<\/p>\n
– D\u1ea1ng u\u1ed1ng: Vi\u00ean n\u00e9n, vi\u00ean n\u00e9n gi\u1ea3i ph\u00f3ng ch\u1eadm, nh\u0169 d\u1ecbch u\u1ed1ng<\/p>\n
– D\u1ea1ng thu\u1ed1c nh\u1ecf m\u1eaft, m\u1ee1 m\u1eaft ho\u1eb7c nh\u1ecf tai<\/p>\n
– D\u1ea1ng ti\u00eam truy\u1ec1n t\u0129nh m\u1ea1ch: thu\u1ed1c ti\u00eam truy\u1ec1n, thu\u1ed1c ti\u00eam (dung d\u1ecbch \u0111\u1eadm \u0111\u1eb7c)<\/p>\n
Ciprofloxacin \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p l\u1ea7n \u0111\u1ea7u v\u00e0o n\u0103m 1987, \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn v\u1edbi kh\u1ea3 n\u0103ng t\u00e1c d\u1ee5ng tr\u00ean tr\u1ef1c khu\u1ea9n m\u1ee7 xanh Pseudomona aeruginosa. Hi\u1ec7n nay \u0111\u01b0\u1ee3c WHO \u0111\u01b0a v\u00e0o danh m\u1ee5c thu\u1ed1c thi\u1ebft y\u1ebfu, Ciprofloxacin c\u0169ng n\u1eb1m trong danh m\u1ee5c thu\u1ed1c t\u00e2n d\u01b0\u1ee3c thi\u1ebft y\u1ebfu c\u1ee7a B\u1ed9 Y t\u1ebf v\u00e0 danh m\u1ee5c c\u00e1c thu\u1ed1c t\u00e2n d\u01b0\u1ee3c thu\u1ed9c ph\u1ea1m vi thanh to\u00e1n c\u1ee7a b\u1ea3o hi\u1ec3m y t\u1ebf.<\/p>\n
T\u00ean th\u01b0\u01a1ng m\u1ea1i: Amfacin, Cetraxal, Cifga, Ciloxan, Ciprobay, Cipmedic, Dophacipro, Furect I.V, Logiflox, Mekociprox, Scanax 500,\u2026<\/p>\n
$\"Thu\u1ed1c$
Thu\u1ed1c Ciprobay<\/figcaption><\/figure>\n
T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Ciprofloxacin<\/h2>\n
Ciprofloxacin<\/strong> c\u00f3 t\u00e1c d\u1ee5ng ti\u00eau di\u1ec7t vi khu\u1ea9n do \u1ee9c ch\u1ebf enzym ADN gyrase v\u00e0 topoisomerase IV l\u00e0 nh\u1eefng enzym c\u1ea7n thi\u1ebft cho s\u1ef1 t\u00e1i sinh s\u1ea3n ADN c\u1ee7a vi khu\u1ea9n, l\u00e0m cho vi khu\u1ea9n kh\u00f4ng th\u1ec3 sinh s\u1ea3n nhanh ch\u00f3ng. T\u00e1c d\u1ee5ng in vitro c\u1ee7a Ciprofloxacin m\u1ea1nh h\u01a1n c\u00e1c quinolon th\u1ebf h\u1ec7 1 kh\u00f4ng g\u1eafn fluor, di\u1ec7t khu\u1ea9n \u1edf c\u1ea3 giai \u0111o\u1ea1n ph\u00e1t tri\u1ec3n nhanh v\u00e0 ch\u1eadm. \u1ede n\u1ed3ng \u0111\u1ed9 \u0111i\u1ec1u tr\u1ecb, Ciprofloxacin kh\u00f4ng t\u00e1c \u0111\u1ed9ng l\u00ean topoisomerase \u1edf \u0111\u1ed9ng v\u1eadt c\u00f3 v\u00fa. Thu\u1ed1c c\u00f2n c\u00f3 t\u00e1c d\u1ee5ng h\u1eadu kh\u00e1ng sinh (post-antibiotic effect) v\u00e0 c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ebfn ch\u1ee9c n\u0103ng mi\u1ec5n d\u1ecbch.<\/p>\n
Ph\u1ed5 kh\u00e1ng khu\u1ea9n: Ciprofloxacin c\u00f3 ph\u1ed5 kh\u00e1ng khu\u1ea9n r\u1ed9ng , t\u00e1c \u0111\u1ed9ng l\u00ean ph\u1ea7n l\u1edbn vi khu\u1ea9n g\u00e2y b\u1ec7nh quan tr\u1ecdng:<\/p>\n
Vi khu\u1ea9n \u01b0a kh\u00ed Gram d\u01b0\u01a1ng: Staphylococci, bao g\u1ed3m ch\u1ee7ng sinh penicillinase v\u00e0 kh\u00f4ng sinh penicillinase, m\u1ed9t s\u1ed1 vi khu\u1ea9n MRSA (T\u1ee5 c\u1ea7u kh\u00e1ng Methicillin); Streptococci tuy nhi\u00ean Streptococcus pneumoniae v\u00e0 enterococci k\u00e9m nh\u1ea1y c\u1ea3m, Bacillus spp., Corynebacterium spp\u2026<\/p>\n
Vi khu\u1ea9n \u01b0a kh\u00ed gram \u00e2m: C\u00e1c Enterobacteriaceae, Pseudomonas aeruginosa, Neisseria gonorrhoeae, Haemophilus influenzae, Moraxella catarrharis v\u00e0 N. meningitindis, Helicobacter pylori, Vibro spp.<\/p>\n
Vi khu\u1ea9n k\u1ef5 kh\u00ed: h\u1ea7u h\u1ebft kh\u00e1ng Ciprofloxacin.<\/p>\n
Vi khu\u1ea9n n\u1ed9i b\u00e0o: Mycobacteria, Mycoplasma, Rickettsia, Chlamydia<\/p>\n
$\"Kh\u00e1ng$
Kh\u00e1ng sinh c\u00f3 t\u00e1c d\u1ee5ng tr\u00ean m\u1ed9t s\u1ed1 ch\u1ee7ng t\u1ee5 c\u1ea7u kh\u00e1ng Methicillin<\/figcaption><\/figure>\n
D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h2>\n
H\u1ea5p thu: Ciprofloxacin h\u1ea5p thu r\u1ea5t t\u1ed1t b\u1eb1ng \u0111\u01b0\u1eddng ti\u00eau ho\u00e1, th\u1ee9c \u0103n l\u00e0m ch\u1eadm h\u1ea5p thu nh\u01b0ng kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3. Tuy nhi\u00ean khi s\u1eed d\u1ee5ng th\u1ef1c ph\u1ea9m, s\u1eefa v\u00e0 c\u00e1c ch\u1ea5t c\u00f3 ion kim lo\u1ea1i ho\u00e1 tr\u1ecb II nh\u01b0 Ca^{++<\/sup>, Mg^{++<\/sup> l\u00e0m gi\u1ea3m h\u1ea5p thu Ciprofloxacin v\u00e0 c\u00e1c quinolon kh\u00e1c. Sinh kh\u1ea3 d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng kho\u1ea3ng 70 \u2013 80%, n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a trong m\u00e1u \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 1 \u2013 2 gi\u1edd.<\/p>\n}}
Ph\u00e2n b\u1ed1: Kho\u1ea3ng t\u1eeb 20 \u2013 40% n\u1ed3ng \u0111\u1ed9 thu\u1ed1c li\u1ebfn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng. Ciprofloxacin ph\u00e2n b\u1ed1 r\u1ed9ng kh\u1eafp c\u01a1 th\u1ec3 v\u00e0 th\u00e2m nh\u1eadp t\u1ed1t v\u00e0o c\u00e1c m\u00f4, \u0111\u1ea1t \u0111\u01b0\u1ee3c n\u1ed3ng \u0111\u1ed9 cao t\u1ea1i c\u00e1c v\u1ecb tr\u00ed nhi\u1ec5m khu\u1ea9n. N\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00f4 th\u01b0\u1eddng cao h\u01a1n n\u1ed3ng \u0111\u1ed9 huy\u1ebft thanh, n\u1ed3ng \u0111\u1ed9 trong d\u1ecbch b\u1ea1ch huy\u1ebft v\u00e0 d\u1ecbch ngo\u1ea1i b\u00e0o c\u0169ng g\u1ea7n t\u01b0\u01a1ng \u0111\u01b0\u01a1ng huy\u1ebft thanh. B\u00ecnh th\u01b0\u1eddng thu\u1ed1c kh\u00f3 th\u1ea5m qua d\u1ecbch n\u00e3o tu\u1ef7 tuy nhi\u00ean trong tr\u01b0\u1eddng h\u1ee3p m\u00e0ng n\u00e3o b\u1ecb vi\u00eam th\u00ec t\u1ef7 l\u1ec7 thu\u1ed1c qua nhi\u1ec1u h\u01a1n. Ciprofloxacin \u0111i qua nhau thai v\u00e0 b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9. Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 c\u1ee7a ciprofloxacin r\u1ea5t l\u1edbn (2-3 l\u00edt\/kg th\u1ec3 tr\u1ecdng).<\/p>\n
Chuy\u1ec3n ho\u00e1 v\u00e0 th\u1ea3i tr\u1eeb: Ciprofloxacin \u0111\u01b0\u1ee3c chuy\u1ec3n ho\u00e1 kho\u1ea3ng 1\/3 qua gan, b\u00e0i xu\u1ea5t qua m\u1eadt v\u00e0 th\u1ea3i tr\u1eeb v\u00e0o l\u00f2ng ru\u1ed9t. C\u00e1c ch\u1ea5t chuy\u1ec3n ho\u00e1 \u0111\u1ec1u c\u00f3 ho\u1ea1t t\u00ednh. Kho\u1ea3ng 40 \u2013 50% li\u1ec1u u\u1ed1ng \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 kho\u1ea3ng 15% \u1edf d\u1ea1ng chuy\u1ec3n ho\u00e1 trong khi 70% thu\u1ed1c \u0111\u00e0o th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u khi d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam. Th\u1eddi gian b\u00e1n th\u1ea3i cu\u1ea3 Ciprofloxacin kho\u1ea3ng 3 \u2013 5 gi\u1edd \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng, th\u1eddi gian b\u00e1n th\u1ea3i t\u0103ng l\u00ean \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn suy gi\u1ea3m tuy nhi\u00ean kh\u00f4ng c\u1ea7n ph\u1ea3i gi\u1ea3m li\u1ec1u khi d\u00f9ng cho c\u00e1c b\u1ec7nh nh\u00e2n suy th\u1eadn nh\u1eb9 c\u0169ng nh\u01b0 suy gan.<\/p>\n
C\u00f4ng d\u1ee5ng v\u00e0 ch\u1ec9 \u0111\u1ecbnh<\/h2>\n
Ciprofloxacin<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho c\u00e1c nhi\u1ec5m khu\u1ea9n n\u1eb7ng m\u00e0 c\u00e1c kh\u00e1ng sinh th\u00f4ng th\u01b0\u1eddng kh\u00f4ng c\u00f2n t\u00e1c d\u1ee5ng:<\/p>\n
– Vi\u00eam \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u tr\u00ean v\u00e0 d\u01b0\u1edbi<\/p>\n
– Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng m\u1eadt<\/p>\n
– Nhi\u1ec5m khu\u1ea9n h\u00f4 h\u1ea5p v\u00e0 tai m\u0169i h\u1ecdng<\/p>\n
– Vi\u00eam x\u01b0\u01a1ng \u2013 tu\u1ef7 x\u01b0\u01a1ng; nhi\u1ec5m khu\u1ea9n x\u01b0\u01a1ng kh\u1edbp<\/p>\n
– Vi\u00eam m\u00e0ng trong tim do vi khu\u1ea9n<\/p>\n
– Vi\u00eam d\u1ea1 d\u00e0y \u2013 ru\u1ed9t, l\u1ef5 tr\u1ef1c tr\u00e0ng, t\u1ea3, th\u01b0\u01a1ng h\u00e0n, vi\u00eam ph\u00fac m\u1ea1c<\/p>\n
– Nhi\u1ec5m khu\u1ea9n da v\u00e0 m\u00f4 m\u1ec1m<\/p>\n
– Nhi\u1ec5m khu\u1ea9n huy\u1ebft\u2026<\/p>\n
Ch\u1ec9 \u0111\u1ecbnh \u1edf tr\u1ebb em: Kh\u00f4ng khuy\u1ebfn c\u00e1o ch\u1ec9 \u0111\u1ecbnh cho tr\u1ebb em d\u01b0\u1edbi 18 tu\u1ed5i do nguy c\u01a1 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 ph\u00e1t tri\u1ec3n s\u1ee5n v\u00e0 x\u01b0\u01a1ng kh\u1edbp. Tuy nhi\u00ean trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng nh\u01b0 nhi\u1ec5m khu\u1ea9n Pseudomonas aeruginosa v\u1eabn \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p ch\u1ec9 \u0111\u1ecbnh v\u00e0 d\u1ef1 ph\u00f2ng trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p kh\u00e1c.<\/p>\n
Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng<\/h2>\n
Li\u1ec1u d\u00f9ng: Tu\u1ef3 thu\u1ed9c v\u00e0o lo\u1ea1i nhi\u1ec5m khu\u1ea9n v\u00e0 m\u1ee9c \u0111\u1ed9 n\u1eb7ng nh\u1eb9 c\u1ee7a b\u1ec7nh, li\u1ec1u d\u00f9ng c\u1ea7n thay \u0111\u1ed5i tu\u1ef3 theo \u0111\u00e1p \u1ee9ng l\u00e2m s\u00e0ng v\u00e0 vi sinh v\u1eadt. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb th\u01b0\u1eddng t\u1eeb 1 \u2013 2 tu\u1ea7n nh\u01b0ng c\u0169ng c\u00f3 th\u1ec3 d\u00e0i h\u01a1n tu\u1ef3 thu\u1ed9c t\u00ecnh tr\u1ea1ng b\u1ec7nh.<\/p>\n
Ng\u01b0\u1eddi l\u1edbn:<\/p>\n
U\u1ed1ng 250 \u2013 750 mg, c\u00e1ch 12 gi\u1edd \/ l\u1ea7n.<\/p>\n
Ti\u00eam t\u0129nh m\u1ea1ch: 200 \u2013 400 mg c\u00e1ch 12 gi\u1edd\/ l\u1ea7n<\/p>\n
Li\u1ec1u d\u00f9ng c\u00f3 th\u1ec3 s\u1ebd thay \u0111\u1ed5i kh\u00e1c nhau trong c\u00e1c b\u1ec7nh c\u1ee5 th\u1ec3<\/p>\n
Tr\u1ebb em:<\/p>\n
U\u1ed1ng: 20 mg\/kg (t\u1ed1i \u0111a 750mg) 2 l\u1ea7n m\u1ed7i ng\u00e0y<\/p>\n
Truy\u1ec1n t\u0129nh m\u1ea1ch: 10 mg\/kg (t\u1ed1i \u0111a 400mg) 3 l\u1ea7n m\u1ed7i ng\u00e0y cho tr\u1ebb t\u1eeb 1 tu\u1ed5i tr\u1edf l\u00ean<\/p>\n
Tr\u1ebb s\u01a1 sinh: 15 mg\/kg u\u1ed1ng ho\u1eb7c 10 mg\/kg truy\u1ec1n t\u0129nh m\u1ea1ch ng\u00e0y 2 l\u1ea7n<\/p>\n
Tr\u1ebb t\u1eeb 1 \u2013 18 th\u00e1ng tu\u1ed5i: 20 mg\/kg (t\u1ed1i \u0111a 750mg) u\u1ed1ng ng\u00e0y 2 l\u1ea7n ho\u1eb7c 10 mg\/kg (t\u1ed1i \u0111a 400mg) 3 l\u1ea7n m\u1ed7i ng\u00e0y.<\/p>\n
C\u00e1ch d\u00f9ng:<\/p>\n
\u0110\u01b0\u1eddng u\u1ed1ng: D\u1ea1ng h\u1ed7n d\u1ecbch ho\u1eb7c vi\u00ean u\u1ed1ng kh\u00f4ng ph\u1ee5 thu\u1ed9c b\u1eefa \u0103n. Tuy nhi\u00ean vi\u00ean n\u00e9n gi\u1ea3i ph\u00f3ng ch\u1eadm n\u00ean u\u1ed1ng c\u00f9ng b\u1eefa \u0103n \u0111\u1ec3 \u0111\u1ea1t hi\u1ec7u qu\u1ea3 t\u1ed1i \u0111a. Kh\u00f4ng u\u1ed1ng c\u00f9ng v\u1edbi s\u1eefa, s\u1eefa chua ho\u1eb7c c\u00e1c ch\u1ebf ph\u1ea9m c\u00f3 Calci do l\u00e0m gi\u1ea3m h\u1ea5p thu thu\u1ed1c, u\u1ed1ng nhi\u1ec1u n\u01b0\u1edbc v\u00e0 kh\u00f4ng n\u00ean u\u1ed1ng c\u00e1c thu\u1ed1c kh\u00e1ng acid tr\u01b0\u1edbc khi u\u1ed1ng Ciprofloxacin. Vi\u00ean n\u00e9n gi\u1ea3i ph\u00f3ng ch\u1eadm, khi u\u1ed1ng nu\u1ed1t nguy\u00ean vi\u00ean, kh\u00f4ng b\u1ebb, nghi\u1ec1n ho\u1eb7c nhai.<\/p>\n
\u0110\u01b0\u1eddng try\u1ec1n t\u0129nh m\u1ea1ch: Ciprofloxacin n\u00ean truy\u1ec1n v\u00e0o t\u0129nh m\u1ea1ch l\u1edbn v\u00e0 truy\u1ec1n ch\u1eadm trong 60 ph\u00fat \u0111\u1ec3 gi\u1ea3m \u0111au v\u00e0 k\u00edch \u1ee9ng m\u1ea1nh. Ch\u1ec9 ti\u00eam truy\u1ec1n t\u0129nh m\u1ea1ch khi b\u1ec7nh nh\u00e2n kh\u00f4ng dung n\u1ea1p \u0111\u01b0\u1ee3c qua \u0111\u01b0\u1eddng u\u1ed1ng v\u00e0 n\u00ean chuy\u1ec3n sang u\u1ed1ng khi tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng cho ph\u00e9p.<\/p>\n
$\"Thu\u1ed1c$
Thu\u1ed1c Ciproth<\/figcaption><\/figure>\n
T\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a Ciprofloxacin<\/h2>\n
Th\u01b0\u1eddng g\u1eb7p:<\/p>\n
\u00ad\u00ad\u00ad- Th\u1ea7n kinh trung \u01b0\u01a1ng: ch\u00f3ng m\u1eb7t, m\u1ea5t ng\u1ee7, b\u1ed3n ch\u1ed3n, lo l\u1eafng, m\u01a1 m\u00e0ng, thao th\u1ee9c, s\u1ed1t, \u0111au \u0111\u1ea7u.<\/p>\n
– Da: ph\u00e1t ban<\/p>\n
– Ti\u00eau ho\u00e1: bu\u1ed3n n\u00f4n, n\u00f4n, \u1ec9a ch\u1ea3y, \u0111au b\u1ee5ng, kh\u00f3 ti\u00eau<\/p>\n
– Gan: t\u0103ng AST v\u00e0 ALT<\/p>\n
– T\u1ea1i ch\u1ed7: \u0110au v\u00e0 s\u01b0ng \u0111\u1ecf n\u01a1i ti\u00eam<\/p>\n
– H\u00f4 h\u1ea5p: vi\u00eam m\u0169i<\/p>\n
\u00cdt g\u1eb7p:<\/p>\n
– To\u00e0n th\u00e2n: nh\u1ee9c \u0111\u1ea7u, s\u1ed1t do thu\u1ed1c<\/p>\n
– M\u00e1u: t\u0103ng b\u1ea1ch c\u1ea7u \u01b0a eosin, gi\u1ea3m b\u1ea1ch c\u1ea7u lympho, gi\u1ea3m b\u1ea1ch c\u1ea7u \u0111a nh\u00e2n, thi\u1ebfu m\u00e1u<\/p>\n
– Tim m\u1ea1ch:\u00a0 Nh\u1ecbp tim nhanh<\/p>\n
– TKTW: k\u00edch \u0111\u1ed9ng<\/p>\n
– Ti\u00eau ho\u00e1: R\u1ed1i lo\u1ea1n ti\u00eau ho\u00e1<\/p>\n
– Da: n\u1ed5i ban, ng\u1ee9a, vi\u00eam t\u0129nh m\u1ea1ch th\u00f4ng<\/p>\n
– C\u01a1 x\u01b0\u01a1ng: \u0111au \u1edf c\u00e1c kh\u1edbp, x\u01b0\u01a1ng kh\u1edbp<\/p>\n
Hi\u1ebfm g\u1eb7p:<\/p>\n
\u00ad- To\u00e0n th\u00e2n: ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7<\/p>\n
– TKTW: co gi\u1eadt, l\u00fa l\u1eabn, r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n\u2026<\/p>\n
– Ti\u00eau ho\u00e1: vi\u00eam \u0111\u1ea1i tr\u00e0ng gi\u1ea3 m\u1ea1c<\/p>\n
– Gan: vi\u00eam gan, v\u00e0ng da \u1ee9 m\u1eadt<\/p>\n
– C\u01a1: \u0111au c\u01a1, vi\u00eam g\u00e2n ( g\u00e2n Achile) v\u00e0 m\u00f4 bao quanh; \u0111\u1ee9t g\u00e2n \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi cao tu\u1ed5i khi d\u00f9ng v\u1edbi corticoid.<\/p>\n
Kh\u00e1c: nh\u1ea1y c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng, ph\u00f9 thanh qu\u1ea3n ho\u1eb7c kh\u00f3 th\u1edf, ph\u00f9 ph\u1ed5i, co th\u1eaft ph\u1ebf qu\u1ea3n.<\/p>\n
Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh<\/h2>\n
Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u1edbi b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn v\u1edbi Ciprofloxacin ho\u1eb7c v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c ho\u1eb7c quinolon kh\u00e1c; ng\u01b0\u1eddi b\u1ec7nh \u0111ang \u0111i\u1ec1u tr\u1ecb v\u1edbi tizanidin.<\/p>\n
Kh\u00f4ng d\u00f9ng cho ph\u1ee5 n\u1eef mang thai v\u00e0 \u0111ang cho con b\u00fa tr\u1eeb tr\u01b0\u1eddng h\u1ee3p b\u1eaft bu\u1ed9c.<\/p>\n
Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng Ciprofloxacin<\/h2>\n
– Th\u1eadn tr\u1ecdng khi d\u00f9ng v\u1edbi ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed \u0111\u1ed9ng kinh hay r\u1ed1i lo\u1ea1n h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng, ng\u01b0\u1eddi suy gi\u1ea3m ch\u1ee9c n\u0103ng gan hay ch\u1ee9c n\u0103ng th\u1eadn, ng\u01b0\u1eddi thi\u1ebfu\u00a0 enzym glucose \u2013 6 \u2013 phosphat dehydrogenase, ng\u01b0\u1eddi b\u1ecb nh\u01b0\u1ee3c c\u01a1<\/p>\n
– Kh\u00f4ng n\u00ean d\u00f9ng v\u1edbi ph\u1ee5 n\u1eef c\u00f3 thai, cho con b\u00fa v\u00e0 tr\u1ebb em d\u01b0\u1edbi 18 tu\u1ed5i tr\u1eeb khi th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft<\/p>\n
– Theo d\u00f5i c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n tr\u00ean h\u1ec7 x\u01b0\u01a1ng kh\u1edbp \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00e1c tr\u01b0\u1eddng h\u1ee3p vi\u00eam g\u00e2n, \u0111\u1ee9t g\u00e2n<\/p>\n
– Tr\u00e1nh ti\u1ebfp x\u00fac \u00e1nh s\u00e1ng m\u1eb7t tr\u1eddi v\u00e0 \u0111\u00e8n chi\u1ebfu c\u00f4ng su\u1ea5t l\u1edbn<\/p>\n
– Th\u1eadn tr\u1ecdng tr\u00ean ng\u01b0\u1eddi cao tu\u1ed5i v\u00ec t\u0103ng nguy c\u01a1 k\u00e9o d\u00e0i kho\u1ea3ng QT<\/p>\n
Th\u1eddi k\u1ef3 mang thai: Ciprofloxacin \u0111i qua nhau thai, tuy ch\u01b0a th\u1ea5y nguy c\u01a1 g\u00e2y qu\u00e1i thai tr\u00ean ng\u01b0\u1eddi v\u00e0 \u0111\u1ed9ng v\u1eadt th\u00ed nghi\u1ec7m tuy nhi\u00ean kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai do kh\u1ea3 n\u0103ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn h\u1ec7 x\u01b0\u01a1ng kh\u1edbp c\u1ee7a thu\u1ed1c l\u00ean thai nhi.<\/p>\n
Th\u1eddi k\u1ef3 cho con b\u00fa: Kh\u00f4ng d\u00f9ng cho ph\u1ee5 n\u1eef cho con b\u00fa do Ciprofloxacin b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9 v\u00e0 c\u00f3 th\u1ec3 \u0111\u1ea1t \u0111\u1ee7 n\u1ed3ng \u0111\u1ed9 g\u00e2y h\u1ea1i cho tr\u1ebb. N\u1ebfu d\u00f9ng Ciprofloxacin ph\u1ea3i ng\u1eebng cho con b\u00fa.<\/p>\n
T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h2>\n
– U\u1ed1ng \u0111\u1ed3ng th\u1eddi Ciprofloxacin v\u1edbi theophylin, clozapin, ropinirol, tizanidin c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 c\u00e1c thu\u1ed1c n\u00e0y trong huy\u1ebft thanh. Do \u0111\u00f3 c\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd n\u1ed3ng \u0111\u1ed9 c\u00e1c thu\u1ed1c n\u00e0y trong m\u00e1u.<\/p>\n
– Ciprofloxacin l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng c\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng \u0111\u01b0\u1eddng u\u1ed1ng v\u00e0 c\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng nh\u01b0 glibenclamid, do \u0111\u00f3 c\u1ea7n th\u01b0\u1eddng xuy\u00ean ki\u1ec3m so\u00e1t prothrombin huy\u1ebft ho\u1eb7c glucose m\u00e1u khi d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c n\u00e0y.<\/p>\n
– Methotrexat b\u1ecb \u1ee9c ch\u1ebf b\u00e0i ti\u1ebft qua \u1ed1ng th\u1eadn b\u1edfi Ciprofloxacin n\u00ean l\u00e0m t\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a thu\u1ed1c; c\u00e1c thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid v\u00e0 insulin l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u1ee7a ciprofloxacin.<\/p>\n
– Kh\u00f4ng n\u00ean d\u00f9ng Ciprofloxacin v\u1edbi c\u00e1c ch\u1ebf ph\u1ea9m c\u00f3 ion kim lo\u1ea1i do l\u00e0m gi\u1ea3m sinh kh\u1ea3 d\u1ee5ng c\u1ee7a thu\u1ed1c. U\u1ed1ng chung v\u1edbi didanosin, sulcralfat c\u0169ng l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00e1u.<\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed qu\u00e1 li\u1ec1u<\/h2>\n
Khi b\u1ecb qu\u00e1 li\u1ec1u Ciprofloxacin c\u1ea7n xem x\u00e9t t\u00ecnh tr\u1ea1ng c\u1ee5 th\u1ec3 \u0111\u1ec3 \u00e1p d\u1ee5ng nh\u1eefng bi\u1ec7n ph\u00e1p nh\u01b0: G\u00e2y n\u00f4n, r\u1eeda d\u1ea1 d\u00e0y, l\u1ee3i ti\u1ec3u. Theo d\u00f5i ng\u01b0\u1eddi b\u1ec7nh c\u1ea9n th\u1eadn v\u00e0 \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3, v\u00ed d\u1ee5 nh\u01b0 truy\u1ec1n b\u00f9 \u0111\u1ee7 d\u1ecbch.<\/p>\n
Gi\u00e1 b\u00e1n m\u1ed9t s\u1ed1 thu\u1ed1c c\u00f3 ch\u1ee9a Ciprofloxacin<\/h2>\n
\n
Ciprobay<\/a> c\u00f3 gia\u0301 150000 VN\u0110\/h\u1ed9p 10 vi\u00ean<\/li>\n
Thu\u1ed1c\u00a0Ciproth<\/a> gi\u00e1 300.000 \u0111\u1ed3ng 1 h\u1ed9p<\/li>\n
thu\u1ed1c Scanax 500<\/a> gi\u00e1 200 000 VN\u0110 1 h\u1ed9p<\/li>\n<\/ul>\n
Tr\u00ean \u0111\u00e2y l\u00e0 nh\u1eefng th\u00f4ng tin chu\u1ea9n x\u00e1c v\u00e0 \u0111\u1ea7y \u0111\u1ee7, \u0111\u01b0\u1ee3c tham kh\u1ea3o t\u1eeb c\u00e1c ngu\u1ed3n t\u00e0i li\u1ec7u khoa h\u1ecdc v\u00e0 uy t\u00edn tr\u00ean th\u1ebf gi\u1edbi. Qua b\u00e0i n\u00e0y, hi v\u1ecdng \u0111\u1ed9c gi\u1ea3 \u0111\u00e3 c\u00f3 c\u00e1i nh\u00ecn to\u00e0n di\u1ec7n v\u1ec1 kh\u00e1ng sinh Ciprofloxacin, bi\u1ebft \u0111\u01b0\u1ee3c Ciprofloxacin l\u00e0 thu\u1ed1c g\u00ec? T\u00e1c d\u1ee5ng v\u00e0 C\u00f4ng d\u1ee5ng c\u1ee7a Ciprofloxacin<\/p>\n
Ngu\u1ed3n tham kh\u1ea3o:<\/p>\n
https:\/\/en.wikipedia.org\/wiki\/Ciprofloxacin<\/a><\/p>\n
https:\/\/www.drugbank.ca\/drugs\/DB00537<\/a><\/p>\n
https:\/\/www.webmd.com\/drugs\/2\/drug-7748\/ciprofloxacin-oral\/details<\/a><\/p>\n
Copy vui l\u00f2ng ghi ngu\u1ed3n: vnras.com\/drug<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"
Ciprofloxacin l\u00e0 kh\u00e1ng sinh th\u1ebf h\u1ec7 2 thu\u1ed9c nh\u00f3m Fluoroquinolon th\u01b0\u1eddng d\u00f9ng trong \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n n\u1eb7ng v\u00e0 nghi\u00eam tr\u1ecdng. Trong b\u00e0i n\u00e0y, ch\u00fang t\u00f4i xin g\u1eedi \u0111\u1ebfn \u0111\u1ed9c gi\u1ea3 nh\u1eefng th\u00f4ng tin chi ti\u1ebft v\u00e0 ch\u00ednh x\u00e1c nh\u1ea5t v\u1ec1 Ho\u1ea1t ch\u1ea5t Ciprofloxacin: l\u00e0 thu\u1ed1c g\u00ec? T\u00e1c d\u1ee5ng – C\u00f4ng d\u1ee5ng c\u1ee7a Ciprofloxacin? Li\u1ec1u […]\n","protected":false},"author":490,"featured_media":22127,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-22121","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/22121","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=22121"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/22121\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/22127"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=22121"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=22121"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=22121"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}