{"id":22101,"date":"2019-09-29T11:30:56","date_gmt":"2019-09-29T04:30:56","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?p=22101"},"modified":"2020-09-16T17:07:43","modified_gmt":"2020-09-16T10:07:43","slug":"cefuroxim","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/cefuroxim\/","title":{"rendered":"Cefuroxim kh\u00e1ng sinh Cephalosporin th\u1ebf h\u1ec7 hai"},"content":{"rendered":"

Cefuroxim<\/strong><\/a> l\u00e0 m\u1ed9t kh\u00e1ng sinh \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ea5t ph\u1ed5 bi\u1ebfn trong \u0111i\u1ec1u tr\u1ecb vi\u00eam ph\u1ed5i, vi\u00eam d\u01b0\u1eddng ti\u1ebft ni\u1ec7u… d\u01b0\u1edbi t\u00ean th\u01b0\u01a1ng m\u1ea1i l\u00e0 Zinnat. B\u00e0i vi\u1ebft n\u00e0y, ch\u00fang t\u00f4i xin g\u1eedi \u0111\u1ebfn \u0111\u1ed9c gi\u1ea3 nh\u1eefng th\u00f4ng tin ch\u00ednh x\u00e1c v\u00e0 \u0111\u1ea7y \u0111\u1ee7 nh\u1ea5t v\u1ec1 ho\u1ea1t ch\u1ea5t Cefuroxim: Cefuroxim l\u00e0 thu\u1ed1c g\u00ec<\/strong>? T\u00e1c d\u1ee5ng<\/strong>, C\u00f4ng d\u1ee5ng c\u1ee7a Cefuroxim<\/strong>? Li\u1ec1u d\u00f9ng, nh\u1eefng l\u01b0u \u00fd khi s\u1eed d\u1ee5ng thu\u1ed1c n\u00e0y.<\/p>\n

Cefuroxim l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n
Cefuroxim<\/strong> l\u00e0 m\u1ed9t kh\u00e1ng sinh nh\u00f3m cephalosprorin th\u1ebf h\u1ec7 th\u1ee9 hai, \u0111\u01b0\u1ee3c d\u00f9ng \u0111i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng c\u00e1c b\u1ec7nh nhi\u1ec5m khu\u1ea9n nh\u01b0 vi\u00eam ph\u1ed5i v\u00e0, nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u, nhi\u1ec5m khu\u1ea9n huy\u1ebft, nhi\u1ec5m khu\u1ea9n da v\u00e0 m\u00f4 m\u1ec1m\u2026<\/p>\n
Cefuroxim \u0111\u01b0\u1ee3c d\u00f9ng d\u01b0\u1edbi c\u00e1c d\u1ea1ng<\/p>\n
Cefuroxim axetyl (d\u1ea1ng thu\u1ed1c u\u1ed1ng), li\u1ec1u d\u00f9ng bi\u1ec3u th\u1ecb theo cefuroxim<\/p>\n
H\u1ed7n d\u1ecbch u\u1ed1ng: 125 mg \/ 5 ml; 250 mg \/ 5 ml.<\/p>\n
Vi\u00ean n\u00e9n: 125 mg; 250 mg; 500 mg<\/p>\n
Cefuroxim natri (d\u1ea1ng thu\u1ed1c ti\u00eam), li\u1ec1u d\u00f9ng bi\u1ec3u th\u1ecb theo cefuroxim<\/p>\n
B\u1ed9t pha ti\u00eam: 250 mg, 750 mg, 1.5 g<\/p>\n
Pha v\u1edbi dung m\u00f4i l\u00e0 n\u01b0\u1edbc c\u1ea5t pha ti\u00eam \u0111\u1ec3 ti\u00eam b\u1eafp hay ti\u00eam t\u0129nh m\u1ea1ch ho\u1eb7c pha c\u00f9ng c\u00e1c thu\u1ed1c ti\u00eam truy\u1ec1n \u0111\u1ec3 truy\u1ec1n t\u0129nh m\u1ea1ch.<\/p>\n
Cefuroxim \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p \u0111\u01b0a v\u00e0o \u0111i\u1ec1u tr\u1ecb n\u0103m 1977 d\u1ea1ng thu\u1ed1c ti\u00eam Zinacef c\u1ee7a GSK, d\u1ea1ng thu\u1ed1c u\u1ed1ng Cefuroxim axetyl \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n sau v\u1edbi t\u00ean th\u01b0\u01a1ng m\u1ea1i Zinnat. Thu\u1ed1c n\u1eb1m trong danh m\u1ee5c thu\u1ed1c thi\u1ebft y\u1ebfu c\u1ee7a WHO v\u00e0 danh m\u1ee5c thu\u1ed1c t\u00e2n d\u01b0\u1ee3c thu\u1ed9c ph\u1ea1m vi thanh to\u00e1n c\u1ee7a B\u1ed9 Y t\u1ebf n\u0103m 2015.<\/p>\n
T\u00ean th\u01b0\u01a1ng m\u1ea1i: Actixim, Alaxime, Antinat, Bifumax, Cefaxil, Cefucap, Cefuroxime, Doroxim, Evacef, Furacin, Furonat, Haginat, Kefurox, Maxcefu, Oralfuxim, Phazinat, Tamecef, Travinat, Zinacef, Zinnat\u2026<\/p>\n
M\u00e3 ATC c\u1ee7a Cefuroxim l\u00e0:\u00a0QJ51DC02;\u00a0S01AA27;\u00a0J01DC02<\/p>\n
$\"Thu\u1ed1c$ Thu\u1ed1c Zinnat \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n h\u00f4 h\u00e1p, ti\u1ebft ni\u1ec7u<\/figcaption><\/figure>\n
T\u00e1c d\u1ee5ng c\u1ee7a Cefuroxim<\/h2>\n
D\u1ea1ng thu\u1ed1c u\u1ed1ng Cefuroxim axetyl l\u00e0 ti\u1ec1n thu\u1ed1c kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh, sau khi v\u00e0o c\u01a1 th\u1ec3 \u0111\u01b0\u1ee3c chuy\u1ec3n ho\u00e1 th\u00e0nh Cefuroxim l\u00e0 d\u1ea1ng thu\u1ed1c ti\u00eam m\u1edbi c\u00f3 ho\u1ea1t t\u00ednh. Cefuroxim c\u00f3 t\u00e1c d\u1ee5ng di\u1ec7t khu\u1ea9n do g\u1eafn v\u00e0o protein g\u1eafn v\u1edbi penicillin (PBP) l\u00e0 c\u00e1c protein tham gia v\u00e0o c\u1ea5u t\u1ea1o th\u00e0nh t\u1ebf b\u00e0o vi khu\u1ea9n, c\u0169ng l\u00e0 enzym x\u00fac t\u00e1c cho giai \u0111o\u1ea1n cu\u1ed1i c\u00f9ng trong ph\u1ea3n \u1ee9ng t\u1ea1o th\u00e0nh t\u1ebf b\u00e0o, d\u1eabn \u0111\u1ebfn th\u00e0nh t\u1ebf b\u00e0o vi khu\u1ea9n kh\u00f4ng \u0111\u01b0\u1ee3c t\u1ea1o th\u00e0nh l\u00e0m ti\u00eau di\u1ec7t vi khu\u1ea9n. T\u00e1c d\u1ee5ng di\u1ec7t khu\u1ea9n c\u1ee7a Cefuroxim ph\u1ee5 thu\u1ed9c v\u00e0o th\u1eddi gian, do \u0111\u00f3 m\u1ee5c ti\u00eau c\u1ea7n \u0111\u1ea1t \u0111\u01b0\u1ee3c l\u00e0 duy tr\u00ec n\u1ed3ng \u0111\u1ed9 c\u1ee7a cefuroxim trong huy\u1ebft t\u01b0\u01a1ng >MIC \u0111\u1ec3 t\u0103ng hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb<\/p>\n
$\"Thu\u1ed1c$
C\u00f4ng th\u1ee9c khung x\u01b0\u01a1ng c\u1ee7a Cefuroxime (skeletal formula)<\/figcaption><\/figure>\n
Ph\u1ed5 kh\u00e1ng khu\u1ea9n:<\/p>\n
Vi khu\u1ea9n hi\u1ebfu kh\u00ed Gram d\u01b0\u01a1ng:<\/p>\n
Staphylococcus aureus: ch\u1ee7ng sinh ho\u1eb7c kh\u00f4ng sinh beta lactamase, tr\u1eeb MRSA<\/p>\n
Streptococcus: li\u00ean c\u1ea7u beta tan m\u00e1u nh\u00f3m A; S. pneumoniae<\/p>\n
Ph\u1ea7n l\u1edbn Enterococci v\u00e0 Lysteria monocytogene \u0111\u1ec1u kh\u00e1ng Cefuroxim.<\/p>\n
Vi khu\u1ea9n hi\u1ebfu kh\u00ed Gram \u00e2m:<\/p>\n
C\u00e1c vi khu\u1ea9n thu\u1ed9c h\u1ecd Enterobacteriaceae: Citrobacter spp., Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella v\u00e0 Shigela<\/p>\n
C\u00e1c ch\u1ee7ng Proteus vulgaris, Legionella, Pseudomonas, Campylobacter, Serretia \u0111\u1ec1u kh\u00e1ng<\/p>\n
Cefuroxim c\u00f3 t\u00e1c d\u1ee5ng m\u1ea1nh tr\u00ean Hemophilus influenzae, H. parainfluenzae, Moraxella catarrhalis, Neisseria gonorrheae, N. meningitidis.<\/p>\n
Vi khu\u1ea9n k\u1ef5 kh\u00ed: Actinomyces, Eubacterium, Lactobacillus, Peptococcus, Propionibacterium, m\u1ed9t s\u1ed1 ch\u1ee7ng Clostridium nh\u01b0ng kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng tr\u00ean C. difficile, \u0111a s\u1ed1 Bacteroides fragillis \u0111\u1ec1u kh\u00e1ng Cefuroxim<\/p>\n
$\"Thu\u1ed1c$
Thu\u1ed1c Cefuroxime c\u00f3 t\u00e1c d\u1ee5ng m\u1ea1nh tr\u00ean vi khu\u1ea9n H.influenzae<\/figcaption><\/figure>\n
D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h2>\n
H\u1ea5p thu: M\u1ee9c \u0111\u1ed9 h\u1ea5p thu \u0111\u01b0\u1eddng u\u1ed1ng c\u1ee7a Cefuroxim axetyl thay \u0111\u1ed5i, ph\u1ee5 thu\u1ed9c v\u00e0o d\u1ea1ng b\u00e0o ch\u1ebf v\u00e0 s\u1ef1 c\u00f3 m\u1eb7t c\u1ee7a th\u1ee9c \u0103n: thu\u1ed1c \u0111\u01b0\u1ee3c h\u1ea5p thu t\u1ed1t nh\u1ea5t khi u\u1ed1ng c\u00f9ng b\u1eefa \u0103n. Sinh kh\u1ea3 d\u1ee5ng c\u1ee7a thu\u1ed1c thay \u0111\u1ed5i t\u1eeb 37% n\u1ebfu u\u1ed1ng l\u00fac \u0111\u00f3i v\u00e0 52% n\u1ebfu u\u1ed1ng ngay sau b\u1eefa \u0103n ho\u1eb7c trong b\u1eefa \u0103n. N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh thay \u0111\u1ed5i theo d\u1ea1ng vi\u00ean hay d\u1ea1ng h\u1ed7n d\u1ecbch. Sau khi v\u00e0o c\u01a1 th\u1ec3, cefuroxim axetyl \u0111\u01b0\u1ee3c chuy\u1ec3n ho\u00e1 th\u00e0nh cefuroxim v\u00e0o h\u1ec7 tu\u1ea7n ho\u00e0n. N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh d\u1ea1ng h\u1ed7n d\u1ecbch ch\u1ec9 b\u1eb1ng 71% d\u1ea1ng thu\u1ed1c vi\u00ean do \u0111\u00f3 hai d\u1ea1ng b\u00e0o ch\u1ebf kh\u00f4ng th\u1ec3 thay th\u1ebf nhau theo t\u01b0\u01a1ng quan mg\/mg.<\/p>\n
Ph\u00e2n b\u1ed1: Kho\u1ea3ng 33 \u2013 50% l\u01b0\u1ee3ng cefuroxim trong m\u00e1u li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng. Cefuroxim ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i trong c\u01a1 th\u1ec3, bao g\u1ed3m t\u1ed5 ch\u1ee9c tuy\u1ebfn ti\u1ec1n li\u1ec7t, d\u1ecbch m\u00e0ng ph\u1ed5i, \u0111\u1eddm, d\u1ecbch ti\u1ebft ph\u1ebf qu\u1ea3n, x\u01b0\u01a1ng, m\u1eadt, d\u1ecbch m\u00e0ng b\u1ee5ng, d\u1ecbch r\u1ec9 vi\u00eam, ho\u1ea1t d\u1ecbch v\u00e0 thu\u1ef7 d\u1ecbch. Thu\u1ed1c qua \u0111\u01b0\u1ee3c d\u1ecbch m\u00e0ng n\u00e3o m\u1ed9t ph\u1ea7n nh\u01b0ng ch\u1ec9 \u0111\u1ea1t \u0111\u01b0\u1ee3c n\u1ed3ng \u0111\u1ed9 \u0111i\u1ec1u tr\u1ecb khi m\u00e0ng n\u00e3o b\u1ecb vi\u00eam, tuy nhi\u00ean trong tr\u01b0\u1eddng h\u1ee3p vi\u00eam m\u00e0ng n\u00e3o Cefuroxim kh\u00f4ng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh m\u00e0 thay v\u00e0o \u0111\u00f3 l\u00e0 c\u00e1c cephalosporin th\u1ebf h\u1ec7 ba. Thu\u1ed1c qua \u0111\u01b0\u1ee3c nhau thai v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9. Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 \u1edf ng\u01b0\u1eddi l\u1edbn kho\u1ebb m\u1ea1nh t\u1eeb 9.3 \u2013 15.8 l\u00edt\/ 1.73 m^{2<\/sup><\/p>\n}
Chuy\u1ec3n ho\u00e1 v\u00e0 th\u1ea3i tr\u1eeb: Cefuroxim kh\u00f4ng b\u1ecb chuy\u1ec3n ho\u00e1, th\u1ea3i tr\u1eeb qua th\u1eadn theo c\u1ea3 hai c\u01a1 ch\u1ebf l\u1ecdc \u1edf c\u1ea7u th\u1eadn v\u00e0 b\u00e0i ti\u1ebft \u1edf \u1ed1ng th\u1eadn. Th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a thu\u1ed1c trong huy\u1ebft t\u01b0\u01a1ng t\u1eeb 1 \u2013 2 gi\u1edd, t\u0103ng l\u00ean trong tr\u01b0\u1eddng h\u1ee3p suy th\u1eadn v\u00e0 c\u00f3 th\u1ec3 l\u00ean \u0111\u1ebfn 9 \u2013 16 gi\u1edd, th\u1eddi gian b\u00e1n th\u1ea3i c\u0169ng t\u0103ng l\u00ean \u1edf tr\u1ebb s\u01a1 sinh. Thu\u1ed1c \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 cao trong n\u01b0\u1edbc ti\u1ec3u do kh\u00f4ng b\u1ecb chuy\u1ec3n ho\u00e1. Probenecid c\u1ea1nh tranh th\u1ea3i tr\u1eeb v\u1edbi cefuroxim \u1edf \u1ed1ng th\u1eadn do \u0111\u00f3 l\u00e0m t\u0103ng th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a cefuroxim. Th\u1ea9m ph\u00e2n m\u00e1u v\u00e0 th\u1ea9m ph\u00e2n ph\u00fac m\u1ea1c c\u00f3 th\u1ec3 lo\u1ea1i tr\u1eeb cefuroxim trong tu\u1ea7n ho\u00e0n.<\/p>\n
C\u00f4ng d\u1ee5ng v\u00e0 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a Cefuroxim<\/h2>\n
D\u1ea1ng u\u1ed1ng cefuroxim axetyl: \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n nh\u1eb9 \u0111\u1ebfn v\u1eeba \u1edf \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p do vi khu\u1ea9n g\u00e2y ra:<\/p>\n
– Ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam tai gi\u1eefa ( do S. pneumoniae, H. influenzae, Moraxella catarrhalis k\u1ec3 c\u1ea3 ch\u1ee7ng sinh beta lactamase ho\u1eb7c do S. pyogenes)<\/p>\n
– Ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam xoang t\u00e1i ph\u00e1t, vi\u00eam amidan (do S. pneumoniae, H. influenzae)<\/p>\n
– Ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam h\u1ecdng t\u00e1i ph\u00e1t (do S. pyogenes, li\u00ean c\u1ea7u tan huy\u1ebft nh\u00f3m A)<\/p>\n
– Ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam ph\u1ebf qu\u1ea3n (do S. pneumoniae ho\u1eb7c H. influenzae)<\/p>\n
– Ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb vi\u00eam ph\u1ed5i m\u1eafc ph\u1ea3i t\u1ea1i c\u1ed9ng \u0111\u1ed3ng<\/p>\n
– Ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb b\u1ec7nh l\u1eadu kh\u00f4ng c\u00f3 bi\u1ebfn ch\u1ee9ng v\u00e0 b\u1ec7nh Lyme th\u1eddi k\u1ef3 \u0111\u1ea7u.<\/p>\n
D\u1ea1ng ti\u00eam cefuroxim natri:<\/p>\n
– Ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n th\u1ec3 n\u1eb7ng \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p d\u01b0\u1edbi (k\u1ec3 c\u1ea3 vi\u00eam ph\u1ed5i)<\/p>\n
– Ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n da v\u00e0 m\u00f4 m\u1ec1m<\/p>\n
– Ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n x\u01b0\u01a1ng kh\u1edbp<\/p>\n
– Ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u \u2013 sinh d\u1ee5c<\/p>\n
– Ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n huy\u1ebft<\/p>\n
– D\u1ef1 ph\u00f2ng nhi\u1ec5m khu\u1ea9n trong ph\u1eabu thu\u1eadt<\/p>\n
C\u00e2n nh\u1eafc chuy\u1ec3n t\u1eeb d\u1ea1ng ti\u00eam sang d\u1ea1ng u\u1ed1ng n\u1ebfu t\u00ecnh tr\u1ea1ng nhi\u1ec5m tr\u00f9ng c\u1ee7a b\u1ec7nh nh\u00e2n \u0111\u00e3 \u0111i v\u00e0o \u1ed5n \u0111\u1ecbnh<\/p>\n
Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng<\/h2>\n
D\u1ea1ng u\u1ed1ng: vi\u00ean n\u00e9n v\u00e0 h\u1ed7n d\u1ecbch kh\u00f4ng t\u01b0\u01a1ng \u0111\u01b0\u01a1ng sinh kh\u1ea3 d\u1ee5ng theo li\u1ec1u mg\/mg n\u00ean kh\u00f4ng th\u1ec3 thay th\u1ebf nhau. \u0110\u1ed1i v\u1edbi tr\u1ebb em d\u01b0\u1edbi 3 tu\u1ed5i kh\u00f4ng c\u00f3 kh\u1ea3 n\u0103ng nu\u1ed1t vi\u00ean n\u00e9n n\u00ean d\u00f9ng d\u1ea1ng h\u1ed7n d\u1ecbch thay v\u00ec nghi\u1ec1n vi\u00ean n\u00e9n v\u00e0 tr\u1ed9n v\u1edbi c\u00e1c lo\u1ea1i th\u1ef1c ph\u1ea9m. H\u1ed7n d\u1ecbch n\u00ean \u0111\u01b0\u1ee3c l\u1eafc k\u1ef9 tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng v\u00e0 \u0111\u1eady n\u1eafp ch\u1eb7t sau m\u1ed7i l\u1ea7n l\u1ea5y thu\u1ed1c<\/p>\n
D\u1ea1ng ti\u00eam: Cefuroxim c\u00f3 th\u1ec3 d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam b\u1eafp, ti\u00eam t\u0129nh m\u1ea1ch tr\u1ef1c ti\u1ebfp, truy\u1ec1n t\u0129nh m\u1ea1ch ng\u1eaft qu\u00e3ng v\u00e0 truy\u1ec1n t\u0129nh m\u1ea1ch li\u00ean t\u1ee5c. Trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p c\u1ea7n pha h\u1ed7n d\u1ecbch hay b\u1ed9t pha ti\u00eam v\u1edbi dung m\u00f4i th\u00edch h\u1ee3p theo \u0111\u00fang khuy\u1ebfn c\u00e1o c\u1ee7a nh\u00e0 s\u1ea3n xu\u1ea5t.<\/p>\n
$\"Cefuroxime$
Cefuroxime d\u1ea1ng h\u1ed7n d\u1ecbch – Actixim<\/figcaption><\/figure>\n
Li\u1ec1u d\u00f9ng<\/p>\n
Li\u1ec1u d\u00f9ng cho ng\u01b0\u1eddi l\u1edbn:<\/p>\n
– Nhi\u1ec5m khu\u1ea9n tai m\u0169i h\u1ecdng: U\u1ed1ng 250 \u2013 500 mg, 12 gi\u1edd m\u1ed9t l\u1ea7n, th\u1eddi gian \u0111i\u1ec1u tr\u1ecb 10 ng\u00e0y<\/p>\n
– Nhi\u1ec5m khu\u1ea9n h\u00f4 h\u1ea5p d\u01b0\u1edbi: U\u1ed1ng 500 mg, 12 gi\u1edd m\u1ed9t l\u1ea7n, th\u1eddi gian \u0111i\u1ec1u tr\u1ecb 10 \u2013 14 ng\u00e0y, ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c kh\u00e1ng sinh kh\u00e1c<\/p>\n
– B\u1ec7nh l\u1eadu kh\u00f4ng c\u00f3 bi\u1ebfn ch\u1ee9ng: Ti\u00eam 1g li\u1ec1u duy nh\u1ea5t<\/p>\n
– B\u1ec7nh Lyme m\u1edbi m\u1eafc: U\u1ed1ng 500 mg, 12 gi\u1edd m\u1ed9t l\u1ea7n, th\u1eddi gian \u0111i\u1ec1u tr\u1ecb 20 ng\u00e0y.<\/p>\n
– D\u1ef1 ph\u00f2ng nhi\u1ec5m khu\u1ea9n trong ph\u1eabu thu\u1eadt: Ti\u00eam t\u0129nh m\u1ea1ch 1.5g li\u1ec1u duy nh\u1ea5t tr\u01b0\u1edbc khi ph\u1eabu thu\u1eadt 1 gi\u1edd.<\/p>\n
Li\u1ec1u d\u00f9ng cho tr\u1ebb em<\/p>\n
\u0110\u01b0\u1eddng u\u1ed1ng:<\/p>\n
– Tr\u1ebb em t\u1eeb 3 th\u00e1ng \u0111\u1ebfn 2 tu\u1ed5i: 10 mg\/kg\/l\u1ea7n (t\u1ed1i \u0111a 125mg\/l\u1ea7n), 12 gi\u1edd m\u1ed9t l\u1ea7n<\/p>\n
– Tr\u1ebb em t\u1eeb 2 tu\u1ed5i \u0111\u1ebfn 12 tu\u1ed5i: 15 mg\/kg\/l\u1ea7n (t\u1ed1i \u0111a 250mg\/l\u1ea7n), 12 gi\u1edd m\u1ed9t l\u1ea7n<\/p>\n
– Tr\u1ebb em t\u1eeb 12 \u2013 18 tu\u1ed5i: 250 mg, 12 gi\u1edd m\u1ed9t l\u1ea7n; li\u1ec1u d\u00f9ng c\u00f3 th\u1ec3 t\u0103ng l\u00ean trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m khu\u1ea9n n\u1eb7ng.<\/p>\n
\u0110\u01b0\u1eddng ti\u00eam<\/p>\n
– Tr\u1ebb s\u01a1 sinh \u0111\u1ebfn 7 ng\u00e0y tu\u1ed5i: 25 mg\/kg\/l\u1ea7n, 12 gi\u1edd m\u1ed9t l\u1ea7n, ch\u1ec9 ti\u00eam \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch, li\u1ec1u d\u00f9ng c\u00f3 th\u1ec3 t\u0103ng l\u00ean trong tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m khu\u1ea9n n\u1eb7ng<\/p>\n
– Tr\u1ebb t\u1eeb 7 \u2013 21 ng\u00e0y tu\u1ed5i: 25 mg\/kg\/l\u1ea7n, 8 gi\u1edd m\u1ed9t l\u1ea7n, ch\u1ec9 ti\u00eam \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch<\/p>\n
– Tr\u1ebb t\u1eeb 21 \u2013 28 ng\u00e0y tu\u1ed5i: 25 mg\/kg\/l\u1ea7n, 6 gi\u1edd m\u1ed9t l\u1ea7n, ch\u1ec9 ti\u00eam \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch<\/p>\n
– Tr\u1ebb t\u1eeb 1 th\u00e1ng tu\u1ed5i \u0111\u1ebfn 18 tu\u1ed5i: 20 mg\/kg\/l\u1ea7n (t\u1ed1i \u0111a 1.5g\/l\u1ea7n), 6 \u2013 8 gi\u1edd m\u1ed7i l\u1ea7n<\/p>\n
– D\u1ef1 ph\u00f2ng nhi\u1ec5m khu\u1ea9n trong ph\u1eabu thu\u1eadt: 50 mg\/kg (t\u1ed1i \u0111a 1.5g) ti\u00eam t\u0129nh m\u1ea1ch<\/p>\n
Tr\u01b0\u1eddng h\u1ee3p suy th\u1eadn: V\u1edbi b\u1ec7nh nh\u00e2n c\u00f3 Cl_{Cr <\/sub>> 20 ml\/ph\u00fat kh\u00f4ng c\u1ea7n gi\u1ea3m li\u1ec1u, v\u1edbi b\u1ec7nh nh\u00e2n c\u00f3 Cl_{Cr<\/sub> < 20 ml\/ph\u00fat c\u1ea7n gi\u1ea3m li\u1ec1u d\u00f9ng m\u1ed9t l\u1ea7n ho\u1eb7c t\u0103ng th\u1eddi gian gi\u1eefa hai l\u1ea7n d\u00f9ng thu\u1ed1c.<\/p>\n}}
T\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a Cefuroxim<\/h2>\n
Th\u01b0\u1eddng g\u1eb7p<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 to\u00e0n th\u00e2n: \u0111au r\u00e1t t\u1ea1i ch\u1ed7, vi\u00eam t\u0129nh m\u1ea1ch huy\u1ebft kh\u1ed1i t\u1ea1i n\u01a1i ti\u00eam truy\u1ec1n<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean ti\u00eau ho\u00e1: ti\u00eau ch\u1ea3y<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean da: m\u00e0y \u0111ay, ng\u1ee9a.<\/p>\n
\u00cdt g\u1eb7p<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 to\u00e0n th\u00e2n: ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7, b\u1ed9i nhi\u1ec5m Candida<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean m\u00e1u: t\u0103ng b\u1ea1ch c\u1ea7u \u01b0a eosin, gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean ti\u00eau ho\u00e1: ti\u00eau ch\u1ea3y, bu\u1ed3n n\u00f4n<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean da: m\u00e0y \u0111ay, ng\u1ee9a<\/p>\n
Hi\u1ebfm g\u1eb7p:<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 to\u00e0n th\u00e2n: s\u1ed1t<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean m\u00e1u: thi\u1ebfu m\u00e1u tan m\u00e1u<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean ti\u00eau ho\u00e1: vi\u00eam \u0111\u1ea1i tr\u00e0ng gi\u1ea3 m\u1ea1c do C. difficile<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean da: h\u1ed3ng ban \u0111a d\u1ea1ng, h\u1ed9i ch\u1ee9ng Steven \u2013 Johnson, ho\u1ea1i t\u1eed bi\u1ec3u b\u00ec nhi\u1ec5m \u0111\u1ed9c<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean gan: v\u00e0ng da \u1ee9 m\u1eadt, t\u0103ng enzym gan v\u00e0 bilirubin huy\u1ebft thanh<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean ti\u1ebft ni\u1ec7u \u2013 sinh d\u1ee5c: vi\u00eam th\u1eadn k\u1ebd, nhi\u1ec5m n\u1ea5m Candida \u00e2m \u0111\u1ea1o<\/p>\n
– T\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean th\u1ea7n kinh trung \u01b0\u01a1ng: c\u01a1n co gi\u1eadt, \u0111au \u0111\u1ea7u, k\u00edch \u0111\u1ed9ng, m\u1ea5t th\u00ednh l\u1ef1c<\/p>\n
Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh<\/h2>\n
– Ng\u01b0\u1eddi b\u1ec7nh c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi kh\u00e1ng sinh nh\u00f3m cephalosporin<\/p>\n
– Ng\u01b0\u1eddi b\u1ec7nh m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t c\u1ee9 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c<\/p>\n
Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng Cefuroxim<\/h2>\n
– Th\u1eadn tr\u1ecdng tr\u00ean b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi kh\u00e1ng sinh nh\u00f3m beta lactam \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00e1c kh\u00e1ng sinh nh\u00f3m cephalosprin. Do c\u00f3 ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn ch\u00e9o gi\u1eefa kh\u00e1ng sinh nh\u00f3m penicillin v\u1edbi kh\u00e1ng sinh nh\u00f3m cephalosporin n\u00ean c\u1ea7n \u0111i\u1ec1u tra v\u00e0 c\u00e2n nh\u1eafc k\u1ef9 tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng thu\u1ed1c<\/p>\n
– Ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn v\u1edbi bi\u1ec3u hi\u1ec7n \u0111a d\u1ea1ng: S\u1ed1t, ng\u1ee9a, \u0111\u1ecf da, m\u00e0y \u0111ay, h\u1ed9i ch\u1ee9ng Steven \u2013 Johnsons, h\u1ed3ng ban \u0111a d\u1ea1ng, ph\u00f9 m\u1ea1ch v\u00e0 c\u00f3 th\u1ec3 s\u1ed1c ph\u1ea3n v\u1ec7. Do \u0111\u00f3 c\u1ea7n chu\u1ea9n b\u1ecb k\u1ef9 c\u00e1c ph\u01b0\u01a1ng ti\u1ec7n v\u00e0 thu\u1ed1c \u0111\u1ec3 \u0111\u1ec1 ph\u00f2ng tr\u01b0\u1eddng h\u1ee3p s\u1ed1c ph\u1ea3n v\u1ec7<\/p>\n
– Th\u1eadn tr\u1ecdng tr\u00ean b\u1ec7nh nh\u00e2n suy th\u1eadn: c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u \u0111\u1ec3 kh\u00f4ng l\u00e0m t\u0103ng qu\u00e1 m\u1ee9c n\u1ed3ng \u0111\u1ed9 cefuroxim trong huy\u1ebft t\u01b0\u01a1ng<\/p>\n
– Th\u1eadn tr\u1ecdng khi \u0111i\u1ec1u tr\u1ecb kh\u00e1ng sinh d\u00e0i ng\u00e0y: cefuroxim c\u00f3 th\u1ec3 l\u00e0m ti\u00eau di\u1ec7t c\u00e1c h\u1ec7 vi khu\u1ea9n ch\u00ed \u0111\u01b0\u1eddng ru\u1ed9t g\u00e2y ti\u00eau ch\u1ea3y v\u00e0 n\u1eb7ng h\u01a1n l\u00e0 b\u1ed9i nhi\u1ec5m C. difficile g\u00e2y vi\u00eam \u0111\u1ea1i tr\u00e0ng gi\u1ea3 m\u1ea1c<\/p>\n
– M\u1ed9t s\u1ed1 kh\u00e1ng sinh (trong \u0111\u00f3 c\u00f3 cefuroxim) c\u00f3 th\u1ec3 g\u00e2y \u0111\u1ed9ng kinh, do \u0111\u00f3 trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb c\u1ea7n gi\u00e1m s\u00e1t ch\u1eb7t ch\u1ebd b\u1ec7nh nh\u00e2n.<\/p>\n
Th\u1eddi k\u1ef3 mang thai: Cefuroxim th\u01b0\u1eddng \u0111\u01b0\u1ee3c xem l\u00e0 an to\u00e0n cho ph\u1ee5 n\u1eef c\u00f3 thai tuy nhi\u00ean ch\u01b0a c\u00f3 \u0111\u1ea7y \u0111\u1ee7 b\u1eb1ng ch\u1ee9ng v\u1ec1 m\u1ee9c \u0111\u1ed9 an to\u00e0n c\u0169ng nh\u01b0 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn thai nhi cho n\u00ean ch\u1ec9 \u0111i\u1ec1u tr\u1ecb cho ph\u1ee5 n\u1eef c\u00f3 thai khi th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft.<\/p>\n
Th\u1eddi k\u1ef3 cho con b\u00fa: Cefuroxim b\u00e0i ti\u1ebft trong s\u1eefa m\u1eb9 v\u1edbi n\u1ed3ng \u0111\u1ed9 th\u1ea5p, nguy c\u01a1 \u1ea3nh h\u01b0\u1edfng tr\u00ean tr\u1ebb b\u00fa c\u00f2n ch\u01b0a \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 \u0111\u1ea7y \u0111\u1ee7. Do \u0111\u00f3 ch\u1ec9 s\u1eed d\u1ee5ng cefuroxim cho tr\u1ebb b\u00fa khi c\u00e2n nh\u1eafc nguy c\u01a1 \u2013 l\u1ee3i \u00edch ho\u1eb7c n\u1ebfu d\u00f9ng c\u00f3 th\u1ec3 ng\u1eebng cho tr\u1ebb b\u00fa<\/p>\n
T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h2>\n
– Probenecid c\u1ea1nh tranh th\u1ea3i tr\u1eeb v\u1edbi Cefuroxim \u1edf \u1ed1ng th\u1eadn do \u0111\u00f3 l\u00e0m t\u0103ng th\u1eddi gian t\u1ed3n t\u1ea1i v\u00e0 n\u1ed3ng \u0111\u1ed9 c\u1ee7a thu\u1ed1c trong huy\u1ebft t\u01b0\u01a1ng<\/p>\n
– T\u0103ng \u0111\u1ed9c t\u00ednh: D\u00f9ng \u0111\u1ed3ng th\u1eddi cefuroxim v\u1edbi kh\u00e1ng sinh nh\u00f3m aminosid ho\u1eb7c l\u1ee3i ti\u1ec3u m\u1ea1nh nh\u01b0 Furosemid c\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a c\u00e1c thu\u1ed1c n\u00e0y l\u00ean th\u1eadn<\/p>\n
– Cefuroxim axetyl c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng vi khu\u1ea9n ch\u00ed \u0111\u01b0\u1eddng ru\u1ed9t do \u0111\u00f3 l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng h\u1ea5p thu estrogen v\u00e0 progesteron, gi\u1ea3m t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c tr\u00e1nh thai \u0111\u01b0\u1eddng u\u1ed1ng<\/p>\n
– Do c\u00f3 t\u00ednh acid n\u00ean kh\u00f4ng pha cefuroxim v\u1edbi c\u00e1c thu\u1ed1c ti\u00eam truy\u1ec1n c\u00f3 t\u00ednh ki\u1ec1m nh\u01b0 Natri bicarbonat. C\u00e1c kh\u00e1ng sinh aminosid c\u0169ng t\u01b0\u01a1ng k\u1ef5 v\u1edbi cefuroxim v\u00ec v\u1eady kh\u00f4ng pha chung \u0111\u1ec3 ti\u00eam truy\u1ec1n.<\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed qu\u00e1 li\u1ec1u<\/h2>\n
Tri\u1ec7u ch\u1ee9ng: Bu\u1ed3n n\u00f4n, n\u00f4n v\u00e0 \u1ec9a ch\u1ea3y. Tuy nhi\u00ean c\u00f3 ph\u1ea3n \u1ee9ng t\u0103ng k\u00edch th\u00edch th\u1ea7n kinh c\u01a1 v\u00e0 co gi\u1eadt, nh\u1ea5t l\u00e0 \u1edf ng\u01b0\u1eddi suy th\u1eadn.<\/p>\n
X\u1eed tr\u00ed: B\u1ea3o v\u1ec7 \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh, h\u1ed7 tr\u1ee3 th\u00f4ng tho\u00e1ng kh\u00ed v\u00e0 truy\u1ec1n d\u1ecbch. N\u1ebfu ph\u00e1t tri\u1ec3n c\u00e1c c\u01a1n co gi\u1eadt, ng\u1eebng ngay vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c; c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng c\u00e1c li\u1ec7u ph\u00e1p ch\u1ed1ng co gi\u1eadt n\u1ebfu c\u00f3 ch\u1ec9 \u0111\u1ecbnh v\u1ec1 l\u00e2m s\u00e0ng. Th\u1ea9m t\u00e1ch m\u00e1u c\u00f3 th\u1ec3 lo\u1ea1i b\u1ecf thu\u1ed1c kh\u1ecfi m\u00e1u, nh\u01b0ng ph\u1ea7n l\u1edbn vi\u1ec7c \u0111i\u1ec1u tr\u1ecb l\u00e0 h\u1ed7 tr\u1ee3 gi\u1ea3i quy\u1ebft tri\u1ec7u ch\u1ee9ng.<\/p>\n
Gi\u00e1 b\u00e1n m\u1ed9t s\u1ed1 thu\u1ed1c c\u00f3 ch\u1ee9a Cefuroxim<\/h2>\n
\n
Thu\u1ed1c Amvifuxime 250<\/a> c\u00f3 gi\u00e1 37.000VN\u0110\/h\u1ed9p 1 v\u1ec9 x 10 vi\u00ean<\/li>\n
Thu\u1ed1c kh\u00e1ng sinh Zaniat<\/a>\u00a0gi\u00e1 52.000 VN\u0110\/ H\u1ed9p<\/li>\n
Thu\u1ed1c\u00a0Zinmax Domesco<\/a>\u00a0hi\u00ea\u0323n \u0111\u01b0\u01a1\u0323c ba\u0301n v\u01a1\u0301i gia\u0301 200.000 VN\u0110 tr\u00ean 1 h\u00f4\u0323p 10 vi\u00ean<\/li>\n<\/ul>\n
Ngu\u1ed3n tham kh\u1ea3o:<\/p>\n
https:\/\/en.wikipedia.org\/wiki\/Cefuroxime<\/a><\/p>\n
https:\/\/www.drugbank.ca\/drugs\/DB01112<\/a><\/p>\n
https:\/\/medlineplus.gov\/druginfo\/meds\/a601206.html<\/a><\/p>\n
Copy vui l\u00f2ng ghi ngu\u1ed3n:\u00a0 https:\/\/www.vnras.com\/drug\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"
Cefuroxim l\u00e0 m\u1ed9t kh\u00e1ng sinh \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ea5t ph\u1ed5 bi\u1ebfn trong \u0111i\u1ec1u tr\u1ecb vi\u00eam ph\u1ed5i, vi\u00eam d\u01b0\u1eddng ti\u1ebft ni\u1ec7u… d\u01b0\u1edbi t\u00ean th\u01b0\u01a1ng m\u1ea1i l\u00e0 Zinnat. B\u00e0i vi\u1ebft n\u00e0y, ch\u00fang t\u00f4i xin g\u1eedi \u0111\u1ebfn \u0111\u1ed9c gi\u1ea3 nh\u1eefng th\u00f4ng tin ch\u00ednh x\u00e1c v\u00e0 \u0111\u1ea7y \u0111\u1ee7 nh\u1ea5t v\u1ec1 ho\u1ea1t ch\u1ea5t Cefuroxim: Cefuroxim l\u00e0 thu\u1ed1c g\u00ec? T\u00e1c d\u1ee5ng, […]\n","protected":false},"author":490,"featured_media":22104,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-22101","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/22101","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/490"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=22101"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/22101\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/22104"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=22101"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=22101"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=22101"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}