{"id":13881,"date":"2019-07-11T15:31:28","date_gmt":"2019-07-11T08:31:28","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?p=13881"},"modified":"2019-07-13T16:16:41","modified_gmt":"2019-07-13T09:16:41","slug":"natri-hyaluronat-mot-hoat-chat-nghin-ung-dung-va-gia-tri-trong-nhan-khoa","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/natri-hyaluronat-mot-hoat-chat-nghin-ung-dung-va-gia-tri-trong-nhan-khoa\/","title":{"rendered":"Natri hyaluronat \u2013 M\u1ed9t ho\u1ea1t ch\u1ea5t, ngh\u00ecn \u1ee9ng d\u1ee5ng v\u00e0 gi\u00e1 tr\u1ecb trong nh\u00e3n khoa"},"content":{"rendered":"

C\u00e1i t\u00ean ho\u1ea1t ch\u1ea5t kh\u00f3 \u0111\u1ecdc n\u00e0y c\u00f3 v\u1ebb l\u1ea1 l\u1eabm v\u1edbi \u0111\u1ea1i \u0111a s\u1ed1 ng\u01b0\u1eddi \u0111\u01b0\u1ee3c h\u1ecfi nh\u01b0ng n\u1ebfu nh\u1eafc \u0111\u1ebfn s\u1ea3n ph\u1ea9m l\u00e0m \u0111\u1eb9p g\u1ecdi t\u1eaft l\u00e0 \u201cFiller\u201d th\u00ec \u0111\u1ea3m b\u1ea3o s\u1ebd c\u00f3 nhi\u1ec1u ng\u01b0\u1eddi trong s\u1ed1 h\u1ecd c\u00f3 th\u1ec3 n\u00f3i r\u1ea5t c\u1eb7n k\u1ebd v\u1ec1 n\u00f3. Quay l\u1ea1i m\u1ed9t ch\u00fat v\u1edbi c\u00e1c s\u1ea3n ph\u1ea9m \u0111\u1ea7u ti\u00ean \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m, kho\u1ea3ng cu\u1ed1i nh\u1eefng n\u0103m 1970 v\u00e0 \u0111\u1ea7u nh\u1eefng n\u0103m 1980, bi\u1ec7t d\u01b0\u1ee3c c\u00f3 t\u00ean l\u00e0 Hylartin v\u00e0 Hylartin Vetused \u0111\u00e3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong c\u00e1c th\u1eed nghi\u1ec7m tr\u00ean ng\u01b0\u1eddi v\u00e0 ng\u1ef1a \u0111ua \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p. N\u0103m 1980, s\u1ea3n ph\u1ea9m th\u01b0\u01a1ng m\u1ea1i \u0111\u1ea7u ti\u00ean c\u00f3 ch\u1ee9a natri hyaluronate \u0111\u01b0\u1ee3c b\u00e1n ra th\u1ecb tr\u01b0\u1eddng c\u00f3 t\u00ean l\u00e0 Healon, \u0111\u01b0\u1ee3c t\u1ea1o ra b\u1edfi nh\u00e0 khoa h\u1ecdc Endre Alexander Balazs v\u00e0 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi h\u00e3ng d\u01b0\u1ee3c ph\u1ea9m Pharmacia AB t\u1ea1i Th\u1ee5y \u0110i\u1ec3n. \u0110\u1ebfn n\u0103m 1986, natri hyaluronate \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ti\u00eam v\u00e0o trong kh\u1edbp \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb vi\u00eam kh\u1edbp g\u1ed1i v\u1edbi bi\u1ec7t d\u01b0\u1ee3c Hyalart (Hyalgan sau n\u00e0y) c\u1ee7a h\u00e3ng Fidia \u2013 \u00dd. (https:\/\/en.wikipedia.org\/wiki\/Sodium_hyaluronate<\/a>)<\/p>\n

– \u1ee8ng d\u1ee5ng \u1edf tr\u00ean x\u01b0\u01a1ng kh\u1edbp ch\u1ec9 l\u00e0 m\u1ed9t ph\u1ea7n r\u1ea5t nh\u1ecf trong v\u00f4 v\u00e0n gi\u00e1 tr\u1ecb \u0111i\u1ec1u tr\u1ecb kh\u00e1c c\u1ee7a ho\u1ea1t ch\u1ea5t n\u00e0y. S\u1edf d\u0129 natri hyaluronat \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i nh\u01b0 v\u1eady l\u00e0 nh\u1edd v\u00e0o t\u00e1c d\u1ee5ng l\u00e0m ch\u1ea5t b\u00f4i tr\u01a1n m\u00f4 li\u00ean k\u1ebft v\u00e0 c\u00f3 tr\u1ecdng l\u01b0\u1ee3ng ph\u00e2n t\u1eed l\u1edbn gi\u00fap t\u1ea1o ra \u0111\u1ed9 \u0111\u00e0n h\u1ed3i \u0111\u1ec3 b\u1ea3o v\u1ec7 c\u00e1c c\u01a1 quan trong c\u01a1 th\u1ec3. M\u1ed9t \u1ee9ng d\u1ee5ng n\u1ed5i ti\u1ebfng kh\u00e1c c\u00f3 th\u1ec3 k\u1ec3 \u0111\u1ebfn nh\u01b0 ti\u00eam d\u01b0\u1edbi da \u0111\u1ec3 l\u00e0m gi\u1ea3m n\u1ebfp nh\u0103n tr\u00ean m\u1eb7t. T\u00ednh \u0111\u1ebfn n\u0103m 2017, c\u01a1 quan qu\u1ea3n l\u00fd th\u1ef1c ph\u1ea9m d\u01b0\u1ee3c ph\u1ea9m M\u1ef9 (FDA) \u0111\u00e3 ph\u00ea duy\u1ec7t cho 13 d\u1ea1ng b\u00e0o ch\u1ebf ch\u1ee9a natri hyaluronat \u0111\u01b0\u1ee3c g\u1ecdi chung l\u00e0 \u201cCh\u1ea5t l\u00e0m \u0111\u1ea7y da\u201d. C\u00e1c s\u1ea3n ph\u1ea9m \u0111\u00f3 c\u0169ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 l\u00e0m d\u1ea7y m\u00f4i v\u00e0 c\u00e1c b\u1ed9 ph\u1eadn kh\u00e1c c\u1ee7a c\u01a1 th\u1ec3 m\u1eb7c d\u00f9 kh\u00f4ng ph\u00ea duy\u1ec7t. T\u00e1c d\u1ee5ng \u201cl\u00e0m \u0111\u1ea7y\u201d \u0111\u00f3 ch\u1ec9 l\u00e0 t\u1ea1m th\u1eddi v\u00e0 th\u00f4ng th\u01b0\u1eddng k\u00e9o d\u00e0i kho\u1ea3ng h\u01a1n 06 th\u00e1ng \u1edf h\u1ea7u h\u1ebft ng\u01b0\u1eddi s\u1eed d\u1ee5ng r\u1ed3i t\u1ef1 \u0111\u00e0o th\u1ea3i ra kh\u1ecfi c\u01a1 th\u1ec3. (Juvederm\u00ae c\u1ee7a h\u00e3ng Allergan l\u00e0 m\u1ed9t trong nh\u1eefng lo\u1ea1i \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ph\u1ed5 bi\u1ebfn t\u1ea1i n\u01b0\u1edbc ta).<\/p>\n

\"Juvederm\"
H\u00ecnh \u1ea3nh: thu\u1ed1c l\u00e0m \u0111\u1ea7y Juvederm<\/figcaption><\/figure>\n

– M\u1eb7t kh\u00e1c, b\u1ea3n ch\u1ea5t h\u00f3a l\u00fd c\u1ee7a natri hyaluronat c\u00f2n \u0111\u01b0\u1ee3c t\u1eadn d\u1ee5ng \u1edf d\u1ea1ng b\u00f4i ngo\u00e0i da, ho\u1ea1t \u0111\u1ed9ng nh\u01b0 m\u1ed9t \u201cch\u1ea5t mang\u201d, gi\u00fap t\u0103ng h\u1ea5p thu c\u00e1c ph\u00e2n t\u1eed sinh h\u1ecdc kh\u00e1c v\u00e0o t\u1ebf b\u00e0o bi\u1ec3u m\u00f4 \u0111\u1ec3 t\u0103ng t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb t\u1ea1i ch\u1ed7. T\u00e1c d\u1ee5ng n\u00e0y thay \u0111\u1ed5i ph\u1ee5 thu\u1ed9c v\u00e0o s\u1ee9c kh\u1ecfe c\u1ee7a da v\u00e0 tr\u1ecdng l\u01b0\u1ee3ng ph\u00e2n t\u1eed, ngu\u1ed3n g\u1ed1c c\u1ee7a natri hyaluronat \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng. C\u0169ng ch\u00ednh v\u00ec s\u1ef1 bi\u1ebfn thi\u00ean n\u00e0y, natri hyaluronat \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf v\u1edbi r\u1ea5t nhi\u1ec1u d\u1ea1ng v\u00e0 n\u1ed3ng \u0111\u1ed9 kh\u00e1c nhau \u0111\u1ec3 s\u1eed d\u1ee5ng trong ph\u1eabu thu\u1eadt nh\u00e3n khoa nh\u01b0 thay th\u1ee7y tinh th\u1ec3 nh\u00e2n t\u1ea1o, gh\u00e9p gi\u00e1c m\u1ea1c, ph\u1eabu thu\u1eadt glaucoma, bong v\u00f5ng m\u1ea1c v\u00e0 \u0111\u1eb7c bi\u1ec7t quan tr\u1ecdng trong \u0111i\u1ec1u tr\u1ecb kh\u00f4 m\u1eaft. Trong qu\u00e1 tr\u00ecnh ph\u1eabu thu\u1eadt n\u1eeda ph\u1ea7n tr\u01b0\u1edbc nh\u00e3n c\u1ea7u, vi\u1ec7c b\u01a1m natri hyaluronat gi\u00fap duy tr\u00ec \u0111\u1ed9 s\u00e2u ti\u1ec1n ph\u00f2ng nh\u1edd v\u00e0o t\u00e1c d\u1ee5ng t\u1ea1o \u0111\u1ed9 nh\u1edbt \u0111\u1ec3 h\u1ea1n ch\u1ebf l\u01b0\u1ee3ng n\u01b0\u1edbc tho\u00e1t ra, l\u00e0m gi\u1ea3m t\u1ed5n th\u01b0\u01a1ng \u0111\u1ebfn t\u1ebf b\u00e0o bi\u1ec3u m\u00f4 gi\u00e1c m\u1ea1c v\u00e0 c\u00e1c m\u00f4 xung quanh, \u0111\u1ed3ng th\u1eddi t\u1ea1o ra \u00e1p l\u1ef1c \u0111\u1ec3 \u0111\u1ea9y ng\u01b0\u1ee3c d\u1ecbch k\u00ednh v\u1ec1 ph\u00eda sau, ng\u0103n c\u00e1c bi\u1ebfn ch\u1ee9ng sau ph\u1eabu thu\u1eadt. M\u1ed9t gi\u00e1 tr\u1ecb n\u1eefa trong nh\u00e3n khoa l\u00e0 t\u1ea1o ra m\u00f4i tr\u01b0\u1eddng trong su\u1ed1t \u0111\u1ec3 thu\u1eadn ti\u1ec7n cho vi\u1ec7c quan s\u00e1t trong ph\u1eabu thu\u1eadt v\u00e0 laser quang \u0111\u00f4ng v\u00f5ng m\u1ea1c.<\/p>\n

– Cu\u1ed1i c\u00f9ng, natri hyaluronat l\u00e0 th\u1ebf h\u1ec7 th\u1ee9 ba c\u1ee7a c\u00e1c d\u00f2ng \u201cn\u01b0\u1edbc m\u1eaft nh\u00e2n t\u1ea1o\u201d v\u00e0 c\u0169ng l\u00e0 ho\u1ea1t ch\u1ea5t duy nh\u1ea5t v\u1eeba c\u00f3 t\u00e1c d\u1ee5ng t\u1ea1o ra \u0111\u1ed9 nh\u1edbt \u0111\u1ec3 b\u00f4i tr\u01a1n b\u1ec1 m\u1eb7t nh\u00e3n c\u1ea7u v\u1eeba c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m t\u0103ng t\u1ed1c \u0111\u1ed9 h\u1ed3i ph\u1ee5c t\u1ebf b\u00e0o bi\u1ec3u m\u00f4 k\u1ebft \u2013 gi\u00e1c m\u1ea1c. C\u00e1c s\u1ea3n ph\u1ea9m th\u1ebf h\u1ec7 ba n\u00e0y \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n v\u00e0 n\u00e2ng c\u1ea5p v\u1ec1 m\u1eb7t b\u00e0o ch\u1ebf theo th\u1eddi gian \u2013 t\u1eeb d\u1ea1ng l\u1ecd c\u00f3 ch\u1ea5t b\u1ea3o qu\u1ea3n ph\u1ed5 th\u00f4ng (Benzalkonium clorid \u2013 Sanlein\u00ae0.1% v\u00e0 0.3% c\u1ee7a Santen) \u0111\u1ebfn d\u1ea1ng l\u1ecd c\u00f3 ch\u1ea5t b\u1ea3o qu\u1ea3n \u00edt \u0111\u1ed9c t\u00ednh h\u01a1n (TearBalance\u00ae c\u1ee7a Senju) r\u1ed3i \u0111\u1ebfn d\u1ea1ng t\u00e9p kh\u00f4ng c\u00f3 ch\u1ea5t b\u1ea3o qu\u1ea3n (Vismed\u00ae c\u1ee7a TRB Chemedica) v\u00e0 m\u1edbi nh\u1ea5t l\u00e0 d\u1ea1ng l\u1ecd kh\u00f4ng ch\u1ea5t b\u1ea3o qu\u1ea3n (th\u1eddi gian s\u1eed d\u1ee5ng sau khi m\u1edf n\u1eafp t\u1edbi 03 th\u00e1ng \u2013 Hylo Gel\u00ae c\u1ee7a Ursapharm). M\u1ed9t s\u1ef1 n\u00e2ng c\u1ea5p kh\u00e1c l\u00e0 thay \u0111\u1ed5i \u00e1p su\u1ea5t th\u1ea9m th\u1ea5u c\u1ee7a dung d\u1ecbch thu\u1ed1c t\u1eeb \u0111\u1eb3ng tr\u01b0\u01a1ng sang nh\u01b0\u1ee3c tr\u01b0\u01a1ng \u0111\u1ec3 t\u0103ng th\u1eddi gian l\u01b0u tr\u1eef t\u1ea1i m\u1eaft, ph\u00f9 h\u1ee3p v\u1edbi quan \u0111i\u1ec3m c\u1ee7a Hi\u1ec7p H\u1ed9i Kh\u00f4 M\u1eaft Qu\u1ed1c T\u1ebf DEWS II 2017 v\u1ec1 m\u1ed1i li\u00ean quan gi\u1eefa b\u1ec7nh l\u00fd kh\u00f4 m\u1eaft v\u1edbi s\u1ef1 m\u1ea5t c\u00e2n b\u1eb1ng \u00e1p su\u1ea5t th\u1ea9m th\u1ea5u c\u1ee7a m\u00e0ng phim n\u01b0\u1edbc m\u1eaft.<\/p>\n

\"Sanlein\"
H\u00ecnh \u1ea3nh: thu\u1ed1c Sanlein<\/figcaption><\/figure>\n

– S\u1ef1 thay \u0111\u1ed5i v\u1ec1 m\u1eb7t n\u1ed3ng \u0111\u1ed9 c\u0169ng \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng c\u1ee7a ho\u1ea1t ch\u1ea5t n\u00e0y. \u0110i\u1ec1u c\u1ea7n quan t\u00e2m b\u00e2y gi\u1edd c\u00f3 l\u1ebd l\u00e0 n\u00ean s\u1eed d\u1ee5ng n\u1ed3ng \u0111\u1ed9 n\u00e0o cho t\u1ed1i \u01b0u nh\u1ea5t? M\u1ed7i h\u00e3ng d\u01b0\u1ee3c \u0111\u1ec1u \u0111\u01b0a ra lu\u1eadn \u0111i\u1ec3m \u0111\u1ec3 b\u1ea3o v\u1ec7 s\u1ea3n ph\u1ea9m c\u1ee7a m\u00ecnh nh\u01b0ng n\u1ebfu \u0111\u1ec3 \u00fd th\u1eadt k\u1ef9 l\u00e0 nh\u1eefng nghi\u00ean c\u1ee9u \u0111\u00f3 ch\u1ec9 ti\u1ebfn h\u00e0nh tr\u00ean m\u1ed9t nh\u00f3m c\u00e1 th\u1ec3 ng\u01b0\u1eddi b\u1ec7nh nh\u1ea5t \u0111\u1ecbnh, ho\u1eb7c l\u00e0 kh\u00f4 m\u1eaft nh\u1eb9, ho\u1eb7c l\u00e0 kh\u00f4 m\u1eaft trung b\u00ecnh hay n\u1eb7ng. M\u1ed9t \u0111i\u1ec1u c\u1ea7n l\u01b0u \u00fd khi \u0111i\u1ec1u tr\u1ecb b\u1ec7nh kh\u00f4 m\u1eaft l\u00e0 b\u1ec7nh nh\u00e2n g\u1ea7n nh\u01b0 s\u1ebd ph\u1ea3i g\u1eafn b\u00f3 v\u1edbi thu\u1ed1c \u0111\u1ebfn h\u1ebft cu\u1ed9c \u0111\u1eddi, ngh\u0129a l\u00e0 chi ph\u00ed \u0111i\u1ec1u tr\u1ecb l\u00e2u d\u00e0i s\u1ebd r\u1ea5t c\u1ea7n \u0111\u01b0\u1ee3c t\u00ednh to\u00e1n theo sau hi\u1ec7u qu\u1ea3 c\u1ee7a thu\u1ed1c \u0111i\u1ec1u tr\u1ecb. M\u1ed9t b\u1ec7nh nh\u00e2n b\u1ecb kh\u00f4 m\u1eaft nh\u1eb9 c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng d\u1ea1ng l\u1ecd c\u00f3 ch\u1ea5t b\u1ea3o qu\u1ea3n v\u00e0 n\u1ed3ng \u0111\u1ed9 natri hyaluronat th\u1ea5p v\u00ec ng\u01b0\u1eddi n\u00e0y \u00edt b\u1ecb ph\u1ee5 thu\u1ed9c n\u1eb7ng n\u1ec1 v\u00e0o thu\u1ed1c \u0111\u1ec3 c\u1ea3i thi\u1ec7n tri\u1ec7u ch\u1ee9ng n\u00f3ng r\u00e1t v\u00e0 c\u00f3 th\u1ec3 \u201cc\u00f3 ng\u00e0y nh\u1ecf thu\u1ed1c c\u00f3 ng\u00e0y kh\u00f4ng\u201d, gi\u00fap l\u00e0m gi\u1ea3m nguy c\u01a1 b\u1ecb t\u00edch l\u0169y ch\u1ea5t b\u1ea3o qu\u1ea3n. N\u1ebfu b\u1ec7nh nh\u00e2n kh\u00f4ng ph\u1ea3i lo l\u1eafng v\u1ec1 m\u1eb7t t\u00e0i ch\u00ednh th\u00ec kh\u00f4ng ph\u1ea3i b\u00e0n l\u00e0m g\u00ec, h\u1ecd th\u01b0\u1eddng s\u1ebd ch\u1ecdn ngay c\u00e1c lo\u1ea1i \u201cn\u01b0\u1edbc m\u1eaft nh\u00e2n t\u1ea1o\u201d cao c\u1ea5p nh\u01b0ng n\u1ebfu t\u00e0i ch\u00ednh l\u00e0 v\u1ea5n \u0111\u1ec1 c\u1ea7n \u0111\u01b0\u1ee3c quan t\u00e2m th\u00ec vi\u1ec7c l\u1ef1a ch\u1ecdn thu\u1ed1c ph\u00f9 h\u1ee3p v\u1edbi t\u1eebng c\u00e1 th\u1ec3 s\u1ebd gi\u00fap l\u00e0m gi\u1ea3m g\u00e1nh n\u1eb7ng chi ph\u00ed \u0111i\u1ec1u tr\u1ecb cho b\u1ec7nh nh\u00e2n.<\/p>\n

– Tr\u01b0\u1edbc \u0111\u00e2y t\u1ea1i Vi\u1ec7t Nam, n\u1ed3ng \u0111\u1ed9 0.18% c\u1ee7a bi\u1ec7t d\u01b0\u1ee3c Vismed\u00ae \u0111\u01b0\u1ee3c coi l\u00e0 n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u01b0u nh\u1ea5t v\u00ec ph\u00f9 h\u1ee3p v\u1edbi nhi\u1ec1u m\u1ee9c \u0111\u1ed9 kh\u00f4 m\u1eaft h\u01a1n. Quan \u0111i\u1ec3m \u0111\u00f3 c\u00f3 l\u1ebd \u0111\u00e3 b\u1ecb \u1ea3nh h\u01b0\u1edfng ph\u1ea7n n\u00e0o khi h\u00e3ng Santen \u0111\u01b0a n\u1ed3ng \u0111\u1ed9 0.3% (Sanlein 0.3) v\u1ec1 th\u1ecb tr\u01b0\u1eddng Vi\u1ec7t Nam n\u0103m 2016. V\u00e0 g\u1ea7n \u0111\u00e2y nh\u1ea5t, n\u1ed3ng \u0111\u1ed9 0.5% c\u1ee7a s\u1ea3n ph\u1ea9m Ialuvit\u00ae l\u1ea1i th\u1ec3 hi\u1ec7n gi\u00e1 tr\u1ecb \u0111i\u1ec1u tr\u1ecb t\u1ed1t h\u01a1n n\u1eefa \u0111\u1ed1i v\u1edbi c\u00e1c b\u1ec7nh nh\u00e2n b\u1ecb kh\u00f4 m\u1eaft trung b\u00ecnh v\u00e0 n\u1eb7ng khi h\u1ecd ph\u1ea3n h\u1ed3i c\u1ea3m th\u1ea5y d\u1ec5 ch\u1ecbu h\u01a1n so v\u1edbi c\u00e1c lo\u1ea1i thu\u1ed1c tr\u01b0\u1edbc. Tuy nhi\u00ean, n\u1ebfu s\u1eed d\u1ee5ng n\u1ed3ng \u0111\u1ed9 0.5% tr\u00ean c\u00e1c b\u1ec7nh nh\u00e2n ch\u1ec9 b\u1ecb kh\u00f4 m\u1eaft nh\u1eb9 th\u00ec h\u1ecd l\u1ea1i c\u1ea3m th\u1ea5y kh\u00f4ng tho\u1ea3i m\u00e1i b\u1eb1ng n\u1ed3ng \u0111\u1ed9 0.1% ho\u1eb7c 0.18% v\u00ec b\u00e1m d\u00ednh qu\u00e1 l\u00e2u. \u0110i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c l\u00fd gi\u1ea3i l\u00e0 do thu\u1ed1c c\u00f3 \u0111\u1ed9 nh\u1edbt cao v\u00e0 c\u0169ng c\u00f3 c\u01a1 ch\u1ebf nh\u01b0\u1ee3c tr\u01b0\u01a1ng nh\u01b0 Vismed\u00ae. \u1ede ph\u1ea1m vi b\u00e0i vi\u1ebft n\u00e0y, ad xin ph\u00e9p ch\u1ec9 \u0111\u1ec1 c\u1eadp \u0111\u1ebfn t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m kh\u00f4 m\u1eaft c\u1ee7a ho\u1ea1t ch\u1ea5t natri hyaluronat, c\u00f2n t\u00e1c d\u1ee5ng l\u00e0m l\u00e0nh t\u1ebf b\u00e0o bi\u1ec3u m\u00f4 k\u1ebft \u2013 gi\u00e1c m\u1ea1c s\u1ebd \u0111\u01b0\u1ee3c b\u00e0n lu\u1eadn c\u1ee5 th\u1ec3 \u1edf c\u00e1c b\u00e0i vi\u1ebft sau.<\/p>\n

Nh\u00e0 thu\u1ed1c Chuy\u00ean Khoa M\u1eaft HD H\u00e0 N\u1ed9i c\u00f3 b\u00e1n m\u1ed9t s\u1ed1 lo\u1ea1i \u201cn\u01b0\u1edbc m\u1eaft nh\u00e2n t\u1ea1o\u201d th\u1ebf h\u1ec7 3:<\/p>\n

+ Hyaluron 0.1% (H\u1ed9p 30 \u1ed1ng 0.88ml ch\u1ee9a Natri hyaluronat 0.1%, kh\u00f4ng ch\u1ea5t b\u1ea3o qu\u1ea3n) c\u1ee7a h\u00e3ng Hanlim, s\u1ea3n xu\u1ea5t t\u1ea1i H\u00e0n Qu\u1ed1c. Gi\u00e1 b\u00e1n: 384.000\u0111\/ h\u1ed9p. Gi\u00e1 nh\u1eadp (gi\u00e1 tr\u00fang th\u1ea7u to\u00e0n qu\u1ed1c): 360.000\u0111\/ h\u1ed9p.<\/p>\n

\"hyaluron
H\u00ecnh \u1ea3nh: hyaluron eye drops<\/figcaption><\/figure>\n

+ Vismed 0.18% (H\u1ed9p 20 \u1ed1ng 0.3ml ch\u1ee9a Natri hyaluronat 0.18%, nh\u01b0\u1ee3c tr\u01b0\u01a1ng, kh\u00f4ng ch\u1ea5t b\u1ea3o qu\u1ea3n) c\u1ee7a h\u00e3ng TRB Chemedica, s\u1ea3n xu\u1ea5t t\u1ea1i \u0110\u1ee9c. Gi\u00e1 b\u00e1n: 218.000\u0111\/h\u1ed9p. Gi\u00e1 nh\u1eadp (gi\u00e1 tr\u00fang th\u1ea7u to\u00e0n qu\u1ed1c): 203.993\u0111\/h\u1ed9p.<\/p>\n

\"Thu\u1ed1c
H\u00ecnh \u1ea3nh: Vismed<\/figcaption><\/figure>\n

+ Gilan Comfort 0.18% (H\u1ed9p 30 \u1ed1ng 0.4ml ch\u1ee9a Natri hyaluronat 0.18%, kh\u00f4ng ch\u1ea5t b\u1ea3o qu\u1ea3n) c\u1ee7a h\u00e3ng Solopharm, s\u1ea3n xu\u1ea5t t\u1ea1i Nga. Gi\u00e1 b\u00e1n: 303.000\u0111\/h\u1ed9p. (\u0110\u0103ng k\u00fd d\u01b0\u1edbi d\u1ea1ng v\u1eadt t\u01b0 y t\u1ebf).<\/p>\n

\"Gilan
H\u00ecnh \u1ea3nh: thu\u1ed1c Gilan Comfort<\/figcaption><\/figure>\n

+ Sanlein 0.3% (L\u1ecd 5ml ch\u1ee9a Natri hyaluronat 0.3% c\u00f3 ch\u1ee9a b\u1ea3o qu\u1ea3n Benzalkonium clorid c\u1ea3i ti\u1ebfn) c\u1ee7a h\u00e3ng Santen, s\u1ea3n xu\u1ea5t t\u1ea1i Nh\u1eadt. Gi\u00e1 b\u00e1n: 132.000\u0111. Gi\u00e1 nh\u1eadp (gi\u00e1 tr\u00fang th\u1ea7u to\u00e0n qu\u1ed1c): 126.000\u0111.<\/p>\n

\"Sanlein\"
H\u00ecnh \u1ea3nh: Sanlein<\/figcaption><\/figure>\n

+ Ialuvit 0.5% (h\u1ed9p 15 \u1ed1ng 0.6ml ch\u1ee9a Natri hyaluronat 0.5% +Taurin 0.5% +Vitamin B12 0.05%, nh\u01b0\u1ee3c tr\u01b0\u01a1ng – kh\u00f4ng ch\u1ea5t b\u1ea3o qu\u1ea3n) c\u1ee7a h\u00e3ng Alfa Intes, s\u1ea3n xu\u1ea5t t\u1ea1i Italy. Gi\u00e1 b\u00e1n: 345.000\u0111\/h\u1ed9p. (\u0110\u0103ng k\u00fd d\u01b0\u1edbi d\u1ea1ng v\u1eadt t\u01b0 y t\u1ebf).<\/p>\n

\"Ialuvit\"
H\u00ecnh \u1ea3nh: Ialuvit<\/figcaption><\/figure>\n

+ S\u1ea3n ph\u1ea9m Hylo gel 0.2% 10ml c\u1ee7a h\u00e3ng Ursapharm, s\u1ea3n xu\u1ea5t t\u1ea1i \u0110\u1ee9c, d\u1ea1ng l\u1ecd kh\u00f4ng ch\u1ea5t b\u1ea3o qu\u1ea3n, \u0111\u1ebfn cu\u1ed1i th\u00e1ng 12 m\u1edbi nh\u1eadp v\u1ec1 Vi\u1ec7t Nam.<\/p>\n

\"Hylo
H\u00ecnh \u1ea3nh: Hylo Gel<\/figcaption><\/figure>\n

C\u1ea3m \u01a1n qu\u00fd kh\u00e1ch \u0111\u00e3 \u0111\u1ecdc b\u00e0i v\u00e0 mong nh\u1eadn \u0111\u01b0\u1ee3c nhi\u1ec1u s\u1ef1 chia s\u1ebb t\u1eeb m\u1ecdi ng\u01b0\u1eddi.<\/p>\n

T\u00e1c gi\u1ea3: Th\u1ea1c s\u0129 – D\u01b0\u1ee3c s\u0129\u00a0 Tr\u1ea7n H\u1ea3i \u0110\u00f4ng.<\/p>\n","protected":false},"excerpt":{"rendered":"

C\u00e1i t\u00ean ho\u1ea1t ch\u1ea5t kh\u00f3 \u0111\u1ecdc n\u00e0y c\u00f3 v\u1ebb l\u1ea1 l\u1eabm v\u1edbi \u0111\u1ea1i \u0111a s\u1ed1 ng\u01b0\u1eddi \u0111\u01b0\u1ee3c h\u1ecfi nh\u01b0ng n\u1ebfu nh\u1eafc \u0111\u1ebfn s\u1ea3n ph\u1ea9m l\u00e0m \u0111\u1eb9p g\u1ecdi t\u1eaft l\u00e0 \u201cFiller\u201d th\u00ec \u0111\u1ea3m b\u1ea3o s\u1ebd c\u00f3 nhi\u1ec1u ng\u01b0\u1eddi trong s\u1ed1 h\u1ecd c\u00f3 th\u1ec3 n\u00f3i r\u1ea5t c\u1eb7n k\u1ebd v\u1ec1 n\u00f3. Quay l\u1ea1i m\u1ed9t ch\u00fat v\u1edbi c\u00e1c s\u1ea3n […]\n","protected":false},"author":1,"featured_media":13899,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-13881","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/13881","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=13881"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/13881\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/13899"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=13881"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=13881"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=13881"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}