{"id":12709,"date":"2019-06-29T09:39:55","date_gmt":"2019-06-29T02:39:55","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?p=12709"},"modified":"2019-07-01T10:04:03","modified_gmt":"2019-07-01T03:04:03","slug":"ansm-dinh-chi-luu-hanh-decontractyl-mephenesin","status":"publish","type":"post","link":"https:\/\/vnras.com\/drug\/ansm-dinh-chi-luu-hanh-decontractyl-mephenesin\/","title":{"rendered":"ANSM: \u0110\u00ecnh ch\u1ec9 l\u01b0u h\u00e0nh Decontractyl (mephenesin)"},"content":{"rendered":"

Ng\u00e0y 28\/6\/2019, C\u01a1 quan Qu\u1ea3n l\u00fd D\u01b0\u1ee3c ph\u1ea9m Ph\u00e1p (ANSM) \u0111\u00e3 \u0111\u01b0a tin v\u1ec1 vi\u1ec7c \u0111\u00ecnh ch\u1ec9 l\u01b0u h\u00e0nh thu\u1ed1c gi\u00e3n c\u01a1 Decontractyl (d\u1ea1ng vi\u00ean n\u00e9n v\u00e0 thu\u1ed1c m\u1ee1), quy\u1ebft \u0111\u1ecbnh c\u00f3 hi\u1ec7u l\u1ef1c k\u1ec3 t\u1eeb ng\u00e0y ra c\u00f4ng b\u1ed1<\/h2>\n
Quy\u1ebft \u0111\u1ecbnh \u0111\u00ecnh ch\u1ec9 l\u01b0u h\u00e0nh Decontractyl<\/strong> (mephenesin) b\u1eaft ngu\u1ed3n t\u1eeb k\u1ebft qu\u1ea3 \u0111\u00e1nh gi\u00e1 l\u1ea1i c\u00e1c ch\u1ebf ph\u1ea9m c\u00f3 ch\u1ee9a mephenesin do ANSM kh\u1edfi x\u01b0\u1edbng. \u0110\u00e1nh gi\u00e1 \u0111\u01b0a \u0111\u1ebfn k\u1ebft lu\u1eadn r\u1eb1ng l\u1ee3i \u00edch kh\u00f4ng v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1 khi c\u00e2n nh\u1eafc \u0111\u1ebfn c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 nguy c\u01a1 l\u1ea1m d\u1ee5ng c\u0169ng nh\u01b0 l\u1ec7 thu\u1ed9c thu\u1ed1c trong khi d\u1eef li\u1ec7u v\u1ec1 hi\u1ec7u qu\u1ea3 khi s\u1eed d\u1ee5ng Decontractylch\u01b0a \u0111\u1ea7y \u0111\u1ee7. Do \u0111\u00f3, vi\u00ean n\u00e9n Decontractyl 500 mg v\u00e0 thu\u1ed1c m\u1ee1 Decontracyl Baume s\u1ebd b\u1ecb ng\u1eebng l\u01b0u h\u00e0nh t\u1ea1i Ph\u00e1p t\u1eeb ng\u00e0y 28\/6\/2019 v\u00e0 c\u00e1c l\u00f4 thu\u1ed1c ch\u01b0a s\u1eed d\u1ee5ng t\u1ea1i c\u00e1c nh\u00e0 thu\u1ed1c s\u1ebd b\u1ecb thu h\u1ed3i.<\/p>\n
$\"Mephenesin\"$ <\/p>\n
B\u00ean c\u1ea1nh \u0111\u00f3, ANSM khuy\u1ebfn c\u00e1o c\u00e1c nh\u00e2n vi\u00ean y t\u1ebf kh\u00f4ng k\u00ea \u0111\u01a1n c\u0169ng nh\u01b0 c\u1ea5p ph\u00e1t bi\u1ec7t d\u01b0\u1ee3c Decontractyl. Ng\u01b0\u1eddi b\u1ec7nh \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o kh\u00f4ng ti\u1ebfp t\u1ee5c s\u1eed d\u1ee5ng Decontractyl v\u00e0 tr\u1ea3 l\u1ea1i cho c\u00e1c nh\u00e0 thu\u1ed1c.<\/p>\n
$\"Decontractyl\"$ <\/p>\n
Vi\u00ean n\u00e9n Decontractyl 500 mg l\u00e0 thu\u1ed1c gi\u00e3n c\u01a1 c\u00f3 t\u00e1c d\u1ee5ng tr\u00ean th\u1ea7n kinh trung \u01b0\u01a1ng, \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n t\u1eeb n\u0103m 1949 v\u00e0 b\u1eaft \u0111\u1ea7u l\u01b0u h\u00e0nh t\u1eeb n\u0103m 1998. Thu\u1ed1c \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111au do co th\u1eaft c\u01a1, li\u1ec1u d\u00f9ng 1-2 vi\u00ean\/l\u1ea7n, 3 l\u1ea7n\/ng\u00e0y.<\/p>\n
Thu\u1ed1c m\u1ee1 Decontractyl Baume l\u00e0 ch\u1ebf ph\u1ea9m ph\u1ed1i h\u1ee3p g\u1ed3m c\u00f3 mephenesin v\u00e0 methyl nicotinat. \u0110\u00e2y l\u00e0 d\u1ea1ng thu\u1ed1c d\u00f9ng ngo\u00e0i \u0111\u1ec3 gi\u1ea3m \u0111au t\u1ea1i ch\u1ed7, \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u t\u1eeb n\u0103m 1955 v\u00e0 \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p l\u01b0u h\u00e0nh n\u0103m 1996. Thu\u1ed1c \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb t\u1ea1i ch\u1ed7 h\u1ed7 tr\u1ee3 gi\u1ea3m \u0111au c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb c\u01a1 \u1edf ng\u01b0\u1eddi l\u1edbn.<\/p>\n
$\"Decontractyl\"$ <\/p>\n
C\u1ea3 hai s\u1ea3n ph\u1ea9m \u0111\u1ec1u trong danh m\u1ee5c thu\u1ed1c kh\u00f4ng k\u00ea \u0111\u01a1n (PMF) v\u00e0 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e1t kh\u00f4ng c\u1ea7n \u0111\u01a1n v\u00e0 kh\u00f4ng \u0111\u01b0\u1ee3c b\u1ea3o hi\u1ec3m chi tr\u1ea3.<\/p>\n

L\u1ee3i \u00edch kh\u00f4ng v\u01b0\u1ee3t tr\u1ed9i so v\u1edbi nguy c\u01a1<\/h2>\n
T\u1eeb khi \u0111\u01b0\u1ee3c l\u01b0u h\u00e0nh, c\u00e1c ch\u1ebf ph\u1ea9m Decontractyl \u0111\u01b0\u1eddng u\u1ed1ng v\u00e0 d\u00f9ng t\u1ea1i ch\u1ed7 l\u00e0 c\u00e1c thu\u1ed1c nghi ng\u1edd g\u00e2y ph\u1ea3n \u1ee9ng c\u00f3 h\u1ea1i trong c\u00e1c b\u00e1o c\u00e1o v\u1ec1 c\u1ea3nh gi\u00e1c d\u01b0\u1ee3c (chi ti\u1ebft xem th\u00eam B\u00e1o c\u00e1o cu\u1ed9c h\u1ecdp c\u1ee7a \u1ee6y ban gi\u00e1m s\u00e1t v\u1ec1 th\u0103ng b\u1eb1ng l\u1ee3i \u00edch \u2013 nguy c\u01a1 c\u1ee7a c\u00e1c s\u1ea3n ph\u1ea9m y t\u1ebf, ng\u00e0y 19\/12\/2017). Do \u0111\u00f3, ANSM \u0111\u00e3 b\u1eaft \u0111\u1ea7u \u0111\u00e1nh gi\u00e1 l\u1ea1i c\u00e2n b\u1eb1ng l\u1ee3i \u00edch-nguy c\u01a1 c\u1ee7a c\u00e1c ch\u1ebf ph\u1ea9m n\u00e0y, \u0111\u1eb7c bi\u1ec7t:<\/p>\n
\n
V\u1edbi vi\u00ean n\u00e9n Decontractyl: c\u00e1c ca v\u1ec1 l\u1ea1m d\u1ee5ng v\u00e0 ph\u1ee5 thu\u1ed9c thu\u1ed1c, t\u0103ng li\u1ec1u, kh\u00f3 ch\u1ecbu, c\u1ea3m gi\u00e1c ch\u00f3ng m\u1eb7t v\u00e0 c\u00e1c ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7.<\/li>\n
V\u1edbi thu\u1ed1c m\u1ee1 Decontractyl Baume: ph\u1ea3n \u1ee9ng tr\u00ean da t\u1ea1i v\u1ecb tr\u00ed b\u00f4i thu\u1ed1c nh\u01b0 n\u00f3ng b\u1eebng v\u00e0 n\u1ed5i ban \u0111\u1ecf (m\u1ed9t s\u1ed1 bi\u1ebfn c\u1ed1 \u0111\u00e3 x\u1ea3y ra \u1edf tr\u1ebb em khi c\u00f3 s\u1ef1 ti\u1ebfp x\u00fac da v\u1edbi ng\u01b0\u1eddi l\u1edbn s\u1eed d\u1ee5ng thu\u1ed1c m\u1ee1).<\/li>\n<\/ul>\n
Tr\u00ean c\u01a1 s\u1edf d\u1eef li\u1ec7u hi\u1ec7n c\u00f3 trong \u0111\u00e1nh gi\u00e1 l\u1ea1i n\u00e0y, ANSM cho r\u1eb1ng l\u1ee3i \u00edch m\u00e0 c\u00e1c ch\u1ebf ph\u1ea9m n\u00e0y \u0111em l\u1ea1i kh\u00f4ng v\u01b0\u1ee3t tr\u1ed9i so v\u1edbi nguy c\u01a1, do hi\u1ec7u qu\u1ea3 h\u1ea1n ch\u1ebf trong khi nguy c\u01a1 g\u1eb7p c\u00e1c ph\u1ea3n \u1ee9ng c\u00f3 h\u1ea1i cao v\u00e0 c\u00f3 nhi\u1ec1u l\u1ef1a ch\u1ecdn thay th\u1ebf \u0111i\u1ec1u tr\u1ecb b\u1eb1ng c\u00e1c thu\u1ed1c ho\u1eb7c c\u00e1c bi\u1ec7n ph\u00e1p kh\u00f4ng d\u00f9ng thu\u1ed1c kh\u00e1c.<\/p>\n
Trong b\u1ea3n \u0111i\u1ec3m tin ng\u00e0y 21\/6\/2019, ANSM \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng vi\u1ec7c ng\u1eebng \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Decontractyl kh\u00f4ng l\u00e0m gia t\u0103ng nguy c\u01a1 v\u00e0 b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 \u00e1p d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p thay th\u1ebf kh\u00f4ng d\u00f9ng thu\u1ed1c (nh\u01b0 t\u1eadp th\u1ec3 thao, th\u01b0 gi\u00e3n, v\u1eadt l\u00fd tr\u1ecb li\u1ec7u).<\/p>\n
Do \u0111\u00f3 trong tr\u01b0\u1eddng h\u1ee3p c\u00f3 \u0111au k\u00e9o d\u00e0i, ANSM khuy\u1ebfn c\u00e1o b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c gi\u1ea3m \u0111au nh\u00f3m 1 (paracetamol, NSAID) t\u00f9y thu\u1ed9c v\u00e0o \u0111\u1eb7c \u0111i\u1ec3m c\u00e1 th\u1ec3 t\u1eebng ng\u01b0\u1eddi b\u1ec7nh. B\u1ec7nh nh\u00e2n c\u0169ng n\u00ean g\u1eb7p d\u01b0\u1ee3c s\u1ef9 ho\u1eb7c b\u00e1c s\u1ef9 \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n.<\/p>\n
Ngu\u1ed3n:<\/p>\n
https:\/\/www.vidal.fr\/actualites\/23435\/douleurs_musculaires_decontractyl_mephenesine_retire_du_marche_a_partir_du_28_juin_2019\/?cid=Eml_000487<\/a><\/p>\n
\u0110i\u1ec3m tin: V\u0169 \u0110\u1ee9c Ho\u00e0n, D\u01b0\u01a1ng Kh\u00e1nh Linh<\/p>\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
Ng\u00e0y 28\/6\/2019, C\u01a1 quan Qu\u1ea3n l\u00fd D\u01b0\u1ee3c ph\u1ea9m Ph\u00e1p (ANSM) \u0111\u00e3 \u0111\u01b0a tin v\u1ec1 vi\u1ec7c \u0111\u00ecnh ch\u1ec9 l\u01b0u h\u00e0nh thu\u1ed1c gi\u00e3n c\u01a1 Decontractyl (d\u1ea1ng vi\u00ean n\u00e9n v\u00e0 thu\u1ed1c m\u1ee1), quy\u1ebft \u0111\u1ecbnh c\u00f3 hi\u1ec7u l\u1ef1c k\u1ec3 t\u1eeb ng\u00e0y ra c\u00f4ng b\u1ed1 Quy\u1ebft \u0111\u1ecbnh \u0111\u00ecnh ch\u1ec9 l\u01b0u h\u00e0nh Decontractyl (mephenesin) b\u1eaft ngu\u1ed3n t\u1eeb k\u1ebft qu\u1ea3 \u0111\u00e1nh gi\u00e1 […]\n","protected":false},"author":1,"featured_media":12721,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-12709","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/12709","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=12709"}],"version-history":[{"count":0,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/12709\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/12721"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=12709"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=12709"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=12709"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}