lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng t\u00e1i ph\u00e1t ho\u1eb7c kh\u00e1ng tr\u1ecb<\/strong>.<\/p>\nPh\u01b0\u01a1ng ph\u00e1p nghi\u00ean c\u1ee9u<\/h2>\n
Ch\u00fang t\u00f4i \u0111\u00e3 t\u00ecm ki\u1ebfm s\u1ed5 \u0111\u0103ng k\u00fd chuy\u00ean ng\u00e0nh c\u1ee7a nh\u00f3m B\u1ec7nh l\u00fd \u0111\u01b0\u1eddng ti\u00eau h\u00f3a tr\u00ean v\u00e0 tuy\u1ebfn t\u1ee5y Cochrane, S\u1ed5 \u0111\u0103ng k\u00fd th\u1eed nghi\u1ec7m c\u00f3 ki\u1ec3m so\u00e1t trung t\u00e2m Cochrane (CENTRAL) trong Th\u01b0 vi\u1ec7n Cochrane, MEDLINE, EMBASE, Science Citation Index Expanded v\u00e0 s\u1ed5 \u0111\u0103ng k\u00fd th\u1eed nghi\u1ec7m cho \u0111\u1ebfn th\u00e1ng 9 n\u0103m 2015 \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh c\u00e1c th\u1eed nghi\u1ec7m ng\u1eabu nhi\u00ean v\u00e0 c\u00e1c nghi\u00ean c\u1ee9u kh\u00f4ng ng\u1eabu nhi\u00ean, s\u1eed d\u1ee5ng c\u00e1c chi\u1ebfn l\u01b0\u1ee3c t\u00ecm ki\u1ebfm. Ch\u00fang t\u00f4i c\u0169ng t\u00ecm ki\u1ebfm c\u00e1c t\u00e0i li\u1ec7u tham kh\u1ea3o c\u1ee7a c\u00e1c nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh c\u00e1c nghi\u00ean c\u1ee9u ti\u1ebfp theo.<\/p>\n
Ti\u00eau ch\u00ed l\u1ef1a ch\u1ecdn<\/h2>\n
Ch\u00fang t\u00f4i \u0111\u00e3 xem x\u00e9t c\u00e1c th\u1eed nghi\u1ec7m ng\u1eabu nhi\u00ean c\u00f3 \u0111\u1ed1i ch\u1ee9ng v\u00e0 c\u00e1c nghi\u00ean c\u1ee9u kh\u00f4ng ng\u1eabu nhi\u00ean so s\u00e1nh \u0111i\u1ec1u tr\u1ecb n\u1ed9i khoa v\u1edbi \u0111i\u1ec1u tr\u1ecb ph\u1eabu thu\u1eadt \u1edf nh\u1eefng ng\u01b0\u1eddi b\u1ecb lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng kh\u00e1ng tr\u1ecb ho\u1eb7c t\u00e1i ph\u00e1t, b\u1ea5t k\u1ec3 ng\u00f4n ng\u1eef, ph\u01b0\u01a1ng th\u1ee9c l\u00e0m m\u00f9 ho\u1eb7c xu\u1ea5t b\u1ea3n \u0111\u1ec3 \u0111\u01b0a v\u00e0o t\u1ed5ng quan.<\/p>\n
Thu th\u1eadp s\u1ed1 li\u1ec7u v\u00e0 ph\u00e2n t\u00edch<\/h2>\n
Hai t\u00e1c gi\u1ea3 \u0111\u00e1nh gi\u00e1 \u0111\u00e3 x\u00e1c \u0111\u1ecbnh \u0111\u1ed9c l\u1eadp c\u00e1c th\u1eed nghi\u1ec7m v\u00e0 tr\u00edch xu\u1ea5t d\u1eef li\u1ec7u. Ch\u00fang t\u00f4i \u0111\u00e3 l\u00ean k\u1ebf ho\u1ea1ch t\u00ednh to\u00e1n t\u1ef7 l\u1ec7 r\u1ee7i ro, ch\u00eanh l\u1ec7ch trung b\u00ecnh, ch\u00eanh l\u1ec7ch trung b\u00ecnh chu\u1ea9n h\u00f3a ho\u1eb7c t\u1ef7 l\u1ec7 nguy c\u01a1 v\u1edbi kho\u1ea3ng tin c\u1eady 95% b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng c\u1ea3 m\u00f4 h\u00ecnh fixed-eFect v\u00e0 random-eFects v\u1edbi Review Manager 5 d\u1ef1a tr\u00ean ph\u00e2n t\u00edch \u00fd \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n
Nh\u1eefng k\u1ebft qu\u1ea3 ch\u00ednh<\/h2>\n
Ch\u00fang t\u00f4i ch\u1ec9 thu th\u1eadp \u0111\u01b0\u1ee3c m\u1ed9t nghi\u00ean c\u1ee9u kh\u00f4ng ng\u1eabu nhi\u00ean \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 c\u00e1ch \u0111\u00e2y 30 n\u0103m trong b\u00e0i t\u1ed5ng quan n\u00e0y. Nghi\u00ean c\u1ee9u n\u00e0y bao g\u1ed3m 77 ng\u01b0\u1eddi tham gia b\u1ecb lo\u00e9t d\u1ea1 d\u00e0y v\u00e0 trong \u0111\u00f3 \u0111i\u1ec1u tr\u1ecb n\u1ed9i khoa (thu\u1ed1c \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 histamine H2, thu\u1ed1c kh\u00e1ng axit v\u00e0 ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang) \u0111\u00e3 th\u1ea5t b\u1ea1i trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb trung b\u00ecnh l\u00e0 29 th\u00e1ng. C\u00e1c t\u00e1c gi\u1ea3 kh\u00f4ng n\u00eau r\u00f5 \u0111\u00e2y l\u00e0 nh\u1eefng \u1ed5 lo\u00e9t t\u00e1i ph\u00e1t hay kh\u00e1ng tr\u1ecb. C\u00f3 v\u1ebb nh\u01b0 nh\u1eefng ng\u01b0\u1eddi tham gia kh\u00f4ng c\u00f3 c\u00e1c bi\u1ebfn ch\u1ee9ng tr\u01b0\u1edbc \u0111\u00f3 nh\u01b0 ch\u1ea3y m\u00e1u ho\u1eb7c th\u00f9ng. Trong s\u1ed1 77 ng\u01b0\u1eddi tham gia, 37 ng\u01b0\u1eddi tham gia ti\u1ebfp t\u1ee5c \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c trong khi 40 ng\u01b0\u1eddi tham gia \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng ph\u1eabu thu\u1eadt (c\u1eaft b\u1ecf hang v\u1ecb c\u00f3 ho\u1eb7c kh\u00f4ng c\u1eaft b\u1ecf d\u00e2y th\u1ea7n kinh ph\u1ebf v\u1ecb; c\u1eaft d\u1ea1 d\u00e0y b\u00e1n ph\u1ea7n c\u00f3 ho\u1eb7c kh\u00f4ng c\u00f3 c\u1eaft d\u00e2y th\u1ea7n kinh ph\u1ebf v\u1ecb; c\u1eaft d\u00e2y th\u1ea7n kinh ph\u1ebf v\u1ecb; t\u1ea1o h\u00ecnh m\u00f4n v\u1ecb v\u00e0 kh\u00e2u \u1ed5 lo\u00e9t, kh\u00e2u ho\u1eb7c \u0111\u00f3ng \u1ed5 lo\u00e9t m\u00e0 kh\u00f4ng c\u1ea7n c\u1eaft d\u00e2y th\u1ea7n kinh ph\u1ebf v\u1ecb ho\u1eb7c c\u1eaft b\u1ecf \u1ed5 lo\u00e9t, ch\u1ec9 ph\u1eabu thu\u1eadt c\u1eaft b\u1ecf ph\u1ea7n g\u1ea7n c\u1ee7a d\u1ea1 d\u00e0y ho\u1eb7c t\u1ebf b\u00e0o th\u00e0nh; kh\u00e2u ho\u1eb7c \u0111\u00f3ng \u1ed5 lo\u00e9t k\u00e8m ph\u1eabu thu\u1eadt c\u1eaft b\u1ecf ph\u1ea7n g\u1ea7n c\u1ee7a d\u1ea1 d\u00e0y ho\u1eb7c t\u1ebf b\u00e0o th\u00e0nh). Vi\u1ec7c s\u1eed d\u1ee5ng ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u1ed9i khoa hay ph\u1eabu thu\u1eadt \u0111\u01b0\u1ee3c quy\u1ebft \u0111\u1ecbnh b\u1edfi s\u1edf th\u00edch c\u1ee7a ng\u01b0\u1eddi tham gia ho\u1eb7c b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb.<\/p>\n
C\u00e1c t\u00e1c gi\u1ea3 nghi\u00ean c\u1ee9u \u0111\u00e3 b\u00e1o c\u00e1o r\u1eb1ng hai ng\u01b0\u1eddi tham gia trong nh\u00f3m \u0111i\u1ec1u tr\u1ecb n\u1ed9i khoa (2 trong s\u1ed1 37; 5,4%) b\u1ecb ung th\u01b0 d\u1ea1 d\u00e0y, \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh b\u1eb1ng sinh thi\u1ebft l\u1eb7p \u0111i l\u1eb7p l\u1ea1i. H\u1ecd kh\u00f4ng b\u00e1o c\u00e1o t\u1ef7 l\u1ec7 ng\u01b0\u1eddi tham gia b\u1ecb ung th\u01b0 d\u1ea1 d\u00e0y trong nh\u00f3m \u0111i\u1ec1u tr\u1ecb ph\u1eabu thu\u1eadt. H\u1ecd c\u0169ng kh\u00f4ng b\u00e1o c\u00e1o t\u00e1c \u0111\u1ed9ng c\u1ee7a vi\u1ec7c ch\u1ea9n \u0111o\u00e1n ung th\u01b0 d\u1ea1 d\u00e0y ch\u1eadm tr\u1ec5 trong nh\u00f3m \u0111i\u1ec1u tr\u1ecb n\u1ed9i khoa. H\u1ecd kh\u00f4ng b\u00e1o c\u00e1o b\u1ea5t k\u1ef3 k\u1ebft qu\u1ea3 \u0111\u00e1ng quan t\u00e2m n\u00e0o kh\u00e1c cho t\u1ed5ng quan n\u00e0y (\u0111\u00f3 l\u00e0 ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng li\u00ean quan \u0111\u1ebfn s\u1ee9c kh\u1ecfe (s\u1eed d\u1ee5ng b\u1ea5t k\u1ef3 thang \u0111o \u0111\u00e3 \u0111\u01b0\u1ee3c x\u00e1c nh\u1eadn n\u00e0o), t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng, xu\u1ea5t huy\u1ebft do lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng, th\u1ee7ng \u1ed5 lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng, \u0111au b\u1ee5ng v\u00e0 c\u00e1c tri\u1ec7u ch\u1ee9ng l\u00e2u d\u00e0i t\u1eed vong).<\/p>\n
K\u1ebft lu\u1eadn<\/h2>\n
Ch\u00fang t\u00f4i kh\u00f4ng t\u00ecm th\u1ea5y nghi\u00ean c\u1ee9u n\u00e0o cung c\u1ea5p l\u1ee3i \u00edch v\u00e0 t\u00e1c h\u1ea1i t\u01b0\u01a1ng \u0111\u1ed1i c\u1ee7a \u0111i\u1ec1u tr\u1ecb n\u1ed9i khoa so v\u1edbi ph\u1eabu thu\u1eadt \u0111\u1ed1i v\u1edbi lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng t\u00e1i ph\u00e1t ho\u1eb7c kh\u00e1ng tr\u1ecb. C\u00e1c nghi\u00ean c\u1ee9u \u0111\u00e1nh gi\u00e1 di\u1ec5n ti\u1ebfn t\u1ef1 nhi\u00ean c\u1ee7a lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng t\u00e1i ph\u00e1t v\u00e0 kh\u00e1ng tr\u1ecb c\u1ea7n \u0111\u01b0\u1ee3c \u0111\u1eb7t ra \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh li\u1ec7u c\u00e1c th\u1eed nghi\u1ec7m ng\u1eabu nhi\u00ean c\u00f3 ki\u1ec3m so\u00e1t so s\u00e1nh \u0111i\u1ec1u tr\u1ecb n\u1ed9i khoa v\u00e0 ph\u1eabu thu\u1eadt \u1edf b\u1ec7nh nh\u00e2n lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng t\u00e1i ph\u00e1t ho\u1eb7c kh\u00e1ng tr\u1ecb ho\u1eb7c c\u1ea3 hai c\u00f3 c\u1ea7n thi\u1ebft hay kh\u00f4ng. Nh\u1eefng nghi\u00ean c\u1ee9u nh\u01b0 v\u1eady c\u0169ng s\u1ebd cung c\u1ea5p th\u00f4ng tin cho vi\u1ec7c thi\u1ebft k\u1ebf c\u00e1c th\u1eed nghi\u1ec7m ng\u1eabu nhi\u00ean c\u00f3 \u0111\u1ed1i ch\u1ee9ng nh\u01b0 v\u1eady. Theo d\u00f5i t\u1ed1i thi\u1ec3u hai \u0111\u1ebfn ba n\u0103m s\u1ebd cho ph\u00e9p t\u00ednh to\u00e1n t\u1ef7 l\u1ec7 bi\u1ebfn ch\u1ee9ng v\u00e0 ung th\u01b0 d\u1ea1 d\u00e0y (ch\u1ec9 trong lo\u00e9t d\u1ea1 d\u00e0y) \u1edf lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng t\u00e1i ph\u00e1t v\u00e0 kh\u00e1ng tr\u1ecb. Ngo\u00e0i c\u00e1c bi\u1ebfn ch\u1ee9ng li\u00ean quan \u0111\u1ebfn \u0111i\u1ec1u tr\u1ecb v\u00e0 b\u1ec7nh t\u1eadt, ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng li\u00ean quan \u0111\u1ebfn s\u1ee9c kh\u1ecfe v\u00e0 m\u1ea5t n\u0103ng su\u1ea5t c\u0169ng c\u1ea7n \u0111\u01b0\u1ee3c \u0111o l\u01b0\u1eddng.<\/p>\n","protected":false},"excerpt":{"rendered":"
Gurusamy KS, Pallari E Ng\u01b0\u1eddi d\u1ecbch: BSNT. Nguy\u1ec5n Tr\u1ecdng Ph\u01b0\u1edbc \u2013 Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc Y H\u00e0 N\u1ed9i. Xem \u0111\u1ea7y \u0111\u1ee7 t\u1ea1i \u0111\u00e2y. T\u00d3M T\u1eaeT \u0110\u1eb7t v\u1ea5n \u0111\u1ec1 Lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng kh\u00e1ng tr\u1ecb l\u00e0 nh\u1eefng \u1ed5 lo\u00e9t trong d\u1ea1 d\u00e0y ho\u1eb7c t\u00e1 tr\u00e0ng kh\u00f4ng l\u00e0nh sau 8 \u0111\u1ebfn 12 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb n\u1ed9i khoa […]\n","protected":false},"author":1,"featured_media":109742,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-109739","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-y-te-suc-khoe"],"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/109739","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=109739"}],"version-history":[{"count":1,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/109739\/revisions"}],"predecessor-version":[{"id":109743,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/posts\/109739\/revisions\/109743"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/109742"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=109739"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/categories?post=109739"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/tags?post=109739"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}